On the Diagnostic Role of Morphological Signs of Wild Rose (Rosa L.)

Identification and systematics of species of wild rose (Rosa L.) are often associated with difficulties due to the diversity and variability of morphological features used in this process. They also arise in establishing genetic links between taxa of different ranks. Clarity in the diagnostic role of specific or group of characters is not only theoretical but also of practical importance. Such an attempt is made on the example of species of the genus Rosa from different sections and subsections (R. canina. R. danaiorum, R. ruprechtii, R. marschalliana, R. obtusifolia, R. svanetica, Rosa mollis, R. buschiana, R. pulverulenta, R pomifera, R. iberica, R. pimpinnefolia, etc.) of Chechnya and adjacent territories. The set of signs of the vegetative and generative sphere used in identifying species, subsections, sections has been considered. There was a lack of representativeness for the intraspecific diagnostics of such signs as: “free, immersed columns”, or “sessile stigmas in the hemispherical head above the fetal throat”, “occasionally solid sepals, with downward directed fruits” and others used in sectional diagnoses, because they are characteristic of species of different sections. The authors noted the heterogeneity of the authors’ approach to the characterization of section rank taxa, the inadmissibility of the universal, and the need for a differentiated approach in using the same characteristics when identifying taxa of different levels

Anatomical Review of Certain Carnations of North Caucasus

The article provides an anatomical review of 32 species of the genus Dianthus L. representatives шт Caucasus, i.e. information about the anatomy of their stem. Most of the studied species have a narrow ecology and are confined to different altitudinal zones. The experience of the introduction of these species in the botanical garden of the Chechen State Pedagogical University of Grozny in the conditions of the steppe climate indicates wide ecological amplitude and potential adaptive capabilities of the species. The main limiting factor in the distribution of these species in natural conditions is probably their low competitiveness. Anatomical signs, apparently, do not have any taxonomic significance. The similarity of the anatomical structure of the stems of the Caucasus carnations is evident even in species that are well differentiated morphologically. Anatomical differences between them are mainly quantitative. The smallest taxonomic values for the anatomical features of carnations are the radial dimensions of the epidermal cells, the mechanical (sclerenchymal) ring, conducting system. The most significant for these purposes are the morphological features: the size of the calyx and capsule, the shape and degree of dissection of the lobule plate, the shape and size of the chaffs

Floristic Research of the Biological Reserve “Bragunsky”

Flora of the biological reserve “Bragunsky” of republican significance, located on the territory of three districts of the Chechen Republic (area of 17,000 hectares, forest land – 10.2 thousand hectares) is studied. Its boundaries are indicated. Preliminary studies in the summer-autumn flora of the reserve have revealed 237 species from 175 genera and 53 families, among which more than 15 endemics are of different statuses, 25 relict species are of different geological eras. Dominant by the number of family species are indicated (Asteraceae, Lamiaceae, Rosaceae, Poaceae, Fabaceae, Caryophyllaceae, Apiaceae, Brassicaceae, Cyperaceae, Scrophyliaceae, Orchidaceae), Geographic elements are considered. The general-holarctic and boreal nature of the flora is noted with a significant participation of ancient Mediterranean and binding elements. The prevalence of hemicryptophytes in the reserve flora has been noted – 115 (49.78 %) species, 48 therophytes (20.25 %) and 40 phanerophytes (10 %) and a slight presence of cryptophytes – 4.21 %. The economically and scientifically valuable, as well as rare, red book and protected species are listed

Halophytes of Tersko-kumsk Lowland Area, Their Protection and Rational Use

Article provides a brief analytical review of studies of halophilic flora species of Tersko- Kumsk lowland area. The most important representatives are indicated, the adaptive properties of different halophyte groups are considered. Their resource value is noted (fodder, medicinal, melliferous, tannic, etc.). In the systematic aspect, the halophilic flora exhibits Mediterranean features, dicotyledons dominate in it, club-moss and horsetails are completely absent, ferns are minimally present. In the edaphic relation, most species of halophytes are obligate, confined to one type of substrate, and the vast majority of halophytes are confined to the steppe belt, the subalpine belt, the belt of upland xerophytes and the alpine belt are in descending order, least of all halophytes in the forest belt, individual species live in subnival belt.The question of the protection of solonchak vegetation and solonchak steppes as a peculiar ecosystems, with a distinctive landscape and original flora containing a highly specialized ecological group of plants, which testifies to the relationship of the nature of plants with the environment. Halophilic cenoses can serve as indicators of the soil, chemical composition and depth of groundwater

Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial

Background: Oral semaglutide is the first oral glucagon-like peptide-1 (GLP-1) receptor agonist for glycaemic control in patients with type 2 diabetes. Type 2 diabetes is commonly associated with renal impairment, restricting treatment options. We aimed to investigate the efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment. Methods: This randomised, double-blind, phase 3a trial was undertaken at 88 sites in eight countries. Patients aged 18 years and older, with type 2 diabetes, an estimated glomerular filtration rate of 30–59 mL/min per 1·73 m2, and who had been receiving a stable dose of metformin or sulfonylurea, or both, or basal insulin with or without metformin for the past 90 days were eligible. Participants were randomly assigned (1:1) by use of an interactive web-response system, with stratification by glucose-lowering medication and renal function, to receive oral semaglutide (dose escalated to 14 mg once daily) or matching placebo for 26 weeks, in addition to background medication. Participants and site staff were masked to assignment. Two efficacy-related estimands were defined: treatment policy (regardless of treatment discontinuation or rescue medication) and trial product (on treatment without rescue medication) in all participants randomly assigned. Endpoints were change from baseline to week 26 in HbA1c (primary endpoint) and bodyweight (confirmatory secondary endpoint), assessed in all participants with sufficient data. Safety was assessed in all participants who received at least one dose of study drug. This trial is registered on ClinicalTrials.gov, number NCT02827708, and the European Clinical Trials Registry, number EudraCT 2015-005326-19, and is now complete. Findings: Between Sept 20, 2016, and Sept 29, 2017, of 721 patients screened, 324 were eligible and randomly assigned to oral semaglutide (n=163) or placebo (n=161). Mean age at baseline was 70 years (SD 8), and 168 (52%) of participants were female. 133 (82%) participants in the oral semaglutide group and 141 (88%) in the placebo group completed 26 weeks on treatment. At 26 weeks, oral semaglutide was superior to placebo in decreasing HbA1c (estimated mean change of −1·0 percentage point (SE 0·1; −11 mmol/mol [SE 0·8]) vs −0·2 percentage points (SE 0·1; −2 mmol/mol [SE 0·8]); estimated treatment difference [ETD]: −0·8 percentage points, 95% CI −1·0 to −0·6;

The tertiary relicts in woods of the Chechen Republic and Ingushetia

In article data on new sites of tertiary relicts are resulted and the state of their populations is characterised

Anatomical Review of Certain Carnations of North Caucasus

The article provides an anatomical review of 32 species of the genus Dianthus L. representatives шт Caucasus, i.e. information about the anatomy of their stem. Most of the studied species have a narrow ecology and are confined to different altitudinal zones. The experience of the introduction of these species in the botanical garden of the Chechen State Pedagogical University of Grozny in the conditions of the steppe climate indicates wide ecological amplitude and potential adaptive capabilities of the species. The main limiting factor in the distribution of these species in natural conditions is probably their low competitiveness. Anatomical signs, apparently, do not have any taxonomic significance. The similarity of the anatomical structure of the stems of the Caucasus carnations is evident even in species that are well differentiated morphologically. Anatomical differences between them are mainly quantitative. The smallest taxonomic values for the anatomical features of carnations are the radial dimensions of the epidermal cells, the mechanical (sclerenchymal) ring, conducting system. The most significant for these purposes are the morphological features: the size of the calyx and capsule, the shape and degree of dissection of the lobule plate, the shape and size of the chaffs

ANALYSIS OF ENDEMISM OF THE XEROPHILOUS FLORA IN THE RUSSIAN CAUCASUS

The aim of our research is to study the endemics of the xerophilous flora of the Russian Caucasus in connection with the matter of knowing the genesis.Methods. The study is based on the field research expeditions.Findings. The presence of endemic species in flora is an indicator of its originality, and the degree of originality is determined by the extent of the endemic species. In general, according to our geographic analysis, the number of endemic species in xerophilous flora of the Russian Caucasus accounts for 32% (326 species), of which 25% of all endemic species have natural habitats within entire Caucasus, 66% are widespread in the Greater Caucasus, and 9% in the Pre-Caucasian region.Conclusion. Endemic species of xerophytes of the flora, in their overwhelming majority, are euxerophytes, and most steno-endemics also belong to this group of xerophytes. In a systematic aspect, the leading family, containing the largest number of endemic species, is Asteraceae (in percentage terms - Lamiaceae) and Jurinea is a leading genus (in percentage terms - Psephellus). In relation to the substrate, calcixerophytes are the dominants and most saturated endemics in quantitative terms are the belt of mountain xerophytes. The predominant biomes are hemicryptophytes; as compared with the number of biomorphes, among chamaephytes there is the biggest quantity of endemics

Similar glycaemic control with less nocturnal hypoglycaemia in a 38-week trial comparing the IDegAsp co-formulation with insulin glargine U100 and insulin aspart in basal insulin-treated subjects with type 2 diabetes mellitus.

Aims: To confirm non-inferiority of insulin degludec/insulin aspart (IDegAsp) once-daily (OD) versus insulin glargine (IGlar) U100 OD + insulin aspart (IAsp) OD for HbA(1c) after 26 weeks, and compare efficacy and safety between groups at W26 + W38