On the merits of the Gaussian Mixture as a model for oriented edgel distributions

The aim of this report is to establish the credibility of the Gaussian Mixture Model (GMM) as a model for the distributions of oriented edgels of rigid and biological objects in noisy images. This is tackled in two stages: first, the response of the Soble filter to noisy pixels is analysed to show that the result holds for smooth ridid objects. Second, arguments are presented to support the proposition that the model can also effectively capture the added uncertainty introduced by natural shape variation, as found in images of biological objects. The result has particular application in the extension of the Generalized Hough Transform (GHT) to deformable shapes; in particular if offers a tailored and manipulable alternative to the non-parametric kernel density estimate used by Ecabert and Thiran

The development of the albino rat, Mus norvegicus albinus. I. From the pronuclear stage to the stage of mesoderm anlage; end of the first to the end of the ninth day

No Abstract.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/50236/1/1050260205_ftp.pd

Spatial distribution of early red lesions is a risk factor for development of vision-threatening diabetic retinopathy

Aims/hypothesis Diabetic retinopathy is characterised by morphological lesions related to disturbances in retinal blood flow. It has previously been shown that the early development of retinal lesions temporal to the fovea may predict the development of treatment-requiring diabetic maculopathy. The aim of this study was to map accurately the area where lesions could predict progression to vision-threatening retinopathy. Methods The predictive value of the location of the earliest red lesions representing haemorrhages and/or microaneurysms was studied by comparing their occurrence in a group of individuals later developing vision-threatening diabetic retinopathy with that in a group matched with respect to diabetes type, age, sex and age of onset of diabetes mellitus who did not develop vision-threatening diabetic retinopathy during a similar observation period. Results The probability of progression to vision-threatening diabetic retinopathy was higher in a circular area temporal to the fovea, and the occurrence of the first lesions in this area was predictive of the development of vision-threatening diabetic retinopathy. The calculated peak value showed that the risk of progression was 39.5% higher than the average. There was no significant difference in the early distribution of lesions in participants later developing diabetic maculopathy or proliferative diabetic retinopathy. Conclusions/interpretation The location of early red lesions in diabetic retinopathy is predictive of whether or not individuals will later develop vision-threatening diabetic retinopathy. This evidence should be incorporated into risk models used to recommend control intervals in screening programmes for diabetic retinopathy

Aardrijkskundige, plaatsbeschrijvende en geschiedkundige kaart van Palestina of het Heilige land

2 bladen aaneengeplakt op linnen | Rechtsonder met de pen geschreven : Proefdruk appr. E. Maaskamp | Gekleurd |

Spain and Portugal / drawn by. J. Assheton ; engraved by J. Shury

1 mapa. Al verso segell imprés: ""Spes mea in Deo. Monachan literary Society