Discordant responses to antiretroviral treatment: prevalence, risk factors and associated mortality in Rwanda

Mexico AIDS Conference 200

Risk factors for hepatotoxicity of nevirapine-containing antiretroviral drug regimens in a large antiretroviral treatment program in Rwanda

Mexico AIDS Conference 200

Effect of maize intercrop plant densities on yield and beta-carotene contents of orange-fleshed sweetpotatoes

Despite efforts to demonstrate the value of orange-fleshed sweetpotato (OFSP) (Ipomoea batatas L.) and quality protein maize (Zea mays L.) in combating vitamin A and protein malnutrition, small land holdings by rural poor farmers still limit the crops’ overall production in Africa. As such, intercropping and optimum plant density in cropping systems will help farmers to improve productivity of the crop, and hence, improve household food and nutrition security. This study determined the effect of maize plant population, in a sweetpotato-maize intercrop, on yields and β-carotene content of two popular OFSP cultivars, Ejumula and NASPOT 9 O (Kabode). Each variety was intercropped with maize variety Longe 5, at three plant densities (i.e. 41,666, 55,555 and 88,888 plants ha-1), at Ngetta Zonal Agricultural Research and Development Institute in Uganda. While 55,555 plants of each OFSP cultivar were used for both sole and intercrops, the sole maize plot was 44,444 plants ha-1. Maize and sweetpotato were harvested at 120 and 135 days after planting, respectively. β-carotene content and yield in sweetpotato roots were significantly (P<0.05) reduced by high maize density. Irrespective of maize density, NASPOT 9 O produced more root yields than Ejumula. Land Equivalent Ratios of >1.2 were obtained at maize intercrop densities of 41,666 and 55,555 plants ha-1.Keywords: Ipomoea batatas, land equivalent ratio, Zea may

Health service delay among pulmonary tuberculosis patients presenting to a National Referral Hospital, Kampala, Uganda: a cross sectional study

Introduction: Delay in the diagnosis of pulmonary tuberculosis (PTB) is common in many countries in Sub-Saharan Africa. Timely diagnosis of active tuberculosis is crucial in minimizing morbidity and mortality in the community as well as nosocomial transmission in health care facilities. This study aimed at determining factors associated with health service delay in the diagnosis and initiation of treatment among new PTB patients presenting to the National Referral Hospital-Mulago.Methods: This was a cross-sectional study among eligible new PTB patients presenting at the National referral TB treatment center Mulago hospital, between March to May 2009. The patients were consecutively recruited and interviewed using a semi-structured questionnaire to assess socio- demographic and health service factors. Multivariate logistic regression using odds ratios and 95% confidence intervals was done.Results: Two hundred and sixty six newly diagnosed PTB patients were enrolled, of which 65.4% experienced health systems delay. The median health service delay was 9days (IQR=8-19). Factors associated with health service delay were: 1n-patient (OR= 4.68, 95% CI: 1.91-11.45), secondary as highest level of education attained (OR= 3.56, 95% CI: 1.18-10.74), primary as highest level of education attained (OR= 6.70, 95% CI: 2.13-21.02), presence of fever (OR= 3.28, 95% CI: 1.05-10.79), and patient delay at health facility (OR= 5.01, 95% CI: 1.33-18.9). Conclusion: The study found a significant proportion of Health service delay among pulmonary tuberculosis patients presenting at the referral hospital. Being an in-patient and having fever as a symptom of tuberculosis needs further attention in order to have timely diagnosis. There is need for awareness on TB especially that most of the TB symptoms present like other febrile illnesses such as malaria and needs consideration when patients present to a health facility.Key words: Tuberculosis, health service delay, treatment delay, diagnostic delay, pulmonary tuberculosi

The significance of HIV and non-communicable diseases in Africa

No AbstractKeywords: Human Immunodeficiency Virus, communicable diseases, non-communicable diseases, Rwanda, sub-Saharan Afric

Weekend admission and mortality from acute exacerbations of chronic obstructive pulmonary disease in winter

Historically, acute medical staffing numbers have been lower on weekends and in winter numbers of medical admissions rise. An analysis of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) admissions to Portsmouth Hospitals over a seven-year period was undertaken to examine the effects of admission on a weekend, of winter, and with the opening of a medical admissions unit (MAU). In total, 9,915 admissions with AECOPD were identified. Weekend admissions accounted for 2,071 (20.9%) of cases, winter accounted for 3,026 (30.5%) admissions, and 522 (34.4%) deaths. Adjusted odds ratio (OR) for death on day 1 after winter weekend admission was 2.89 (95% confidence interval (CI) 1.035 to 8.076). After opening the MAU, the OR for death day 1 after weekend winter admission fell from 3.63 (95% CI 1.15 to 11.5) to 1.65 (95% CI 0.14 to 19.01). AECOPD patients have an increased risk of death after admission over a weekend in winter and this effect was reduced by opening a MAU. These findings have implications for the planning of acute care provision in different seasons. © Royal College of Physicians, 2011. All rights reserved

Surface run-off behaviour of bitumen emulsions used for the construction of seals

Paper presented at the 33rd Annual Southern African Transport Conference 7-10 July 2014 "Leading Transport into the Future", CSIR International Convention Centre, Pretoria, South Africa.The application of seals as surfacing on South African roads has increased due to its dual advantage in performance potential and sustainability. The field performance of spray seals depends on a number of factors, and its defects measured predominantly by bleeding and ravelling of the seals. During construction, viscosity is controlled such that the binder is sprayable, but not too low in viscosity as to run off the road surface. To avoid pavement distress resulting from loss of the binder or from inconsistent binder thickness after application, it is important to understand the run-off behaviour of seals. Run-off tests were conducted in the laboratory by constructing surfacing seals with varying texture depths. These seals were constructed on a surface that would allow the user to change the angle of application in order to simulate the spraying of the seals on different road gradients. A movable/mobile spraybar was used to simulate typical conditions as for a spray tanker during construction. Run-off was measured through a gutter system where the emulsions was collected and weighed. An analysis of the run-off results obtained from these experiments, revealed that the spray rate had the largest effect on run-off, followed by texture depth, and gradient.This paper was transferred from the original CD ROM created for this conference. The material was published using Adobe Acrobat 10.1.0 Technology. The original CD ROM was produced by CE Projects cc. Postal Address: PO Box 560 Irene 0062 South Africa. Tel.: +27 12 667 2074 Fax: +27 12 667 2766 E-mail: [email protected]

The tonal residue of the conjoint/disjoint alternation in Rukiga

The Bantu language Rukiga (JE14, Uganda) shows tonal reduction on the verb in a subset of tenses, similar to the conjoint/disjoint alternation in Haya. Whereas in other languages the conjoint/disjoint alternation is usually marked by segmental morphology in at least one tense, Rukiga is unique in showing only tonal reduction. Nevertheless, our analysis shows that tonal reduction in Rukiga is not merely a phonological rule, but it encodes the conjoint/disjoint alternation. Furthermore, we show that tonal reduction in Rukiga is determined by constituent-finality, and there is no direct relation to focus.Theoretical and Experimental Linguistic

Village Baseline Study: Site Analysis Report for Kagera Basin – Rakai, Uganda

The village baseline study of Kyengeza village in the CCAFS site Kagera Basin – Rakai in Uganda took place from 4 to 6 July 2011. Study participants are aware that their food security depends on protecting and appropriately managing natural resources. Nonetheless, there is a general decline in the state of natural resources such as rivers, lakes and forests, and the current use of the same resources is not sustainable over time. The main drivers of such changes in the region are population growth and government policies that have privatised forests and other natural areas previously managed by the village, effectively disempowering the community. There are more organisations operating beyond the locality than those operating in the community. The external organisations started delivering food, tools, medicines and other resources in response to HIV/AIDS. Their ability to mobilise resources, however, is undermining self-help capacity within the village, which is not conducive to sustainable rural development. Radio and organisations are the most frequently used sources of information for agricultural decision- making. There is a relatively active information network compared to other CCAFS sites, and a fair amount of consultation with all kinds of sources of information. This may be linked to high levels of uncertainty associated with climate change and food security

The multifunctionality of ‑o in Rukiga: pronoun, contrastive topic, and mirative marker

This paper discusses the particle -o in Rukiga (Bantu JE14, Uganda), aiming to establish its origin and function. At first sight, the particle appears to be an independent pronoun agreeing in noun class, reported in previous studies as an emphatic pronoun. Based on an extensive analysis of the particle, we argue that, through grammaticalisation, it has developed from a medial demonstrative via the independent pronoun to become a contrastive topic marker. This analysis is supported by various topic and focus tests carried out, which indicate that it combines with topics and is incompatible with focalised referents. We discovered that the particle is also used in exclamative/mirative contexts, expressing (a degree of) unexpectedness and surprise. Our findings indicate that independent morphological topic markers are present in East African languages just as they are in the more analytical West-African languages, and that exclamatives and miratives, which are extremely understudied in Bantu languages, may be associated with the morphological particle -o.NWO276-78-001Descriptive and Comparative Linguistic