Study on Forward Chaining and Reverse Chaining in Expert System

Expert systems are part of a general category of computer applications known as intelligence. Expert system are designed to solve complex problems. Expert Systems is a branch of AI designed to work within a particular domain. To solve expert-level problems, expert systems will need efficient access to a substantial domain knowledge base, and a reasoning mechanism to apply the knowledge to the problems they are given. Usually they will also need to be able to explain, to the users who rely on them, how they have reached their decisions. As an expert is a person who can solve a problem with the domain knowledge. This research paper introduces introduction, parts, application of expert system. and difference between forward chaining and Backward chaining and Exactly meaning of Chaining. ETL tools uses functionality to extract, transform and load data from one system into another system, but our expert advises they're not optimal for application-to-application communication. In artificial intelligence, an expert system is a computer system that emulates the decision-making ability of a human expert. The AI technology has become really advanced and its only matter of time when the machines will be able to learn almost anything. The machine learning algorithms are already very smart, however the Processing power has been a challenge in last decade .Now with the big data and distributed computing revolution this problem has become easy to solve. Many programmers and developers can start programming their own robots and other gadgets on their own. Artificial intelligence is a science and technology based on disciplines such as Computer Science, Biology, Psychology, Linguistics, Mathematics, and Engineering. A major thrust of AI is in the development of computer functions associated with human intelligence, such as reasoning, learning, and problem solving

Enhanced alpha-amylase production using Streptomyces gancidicus ASD by process optimization

845-852The present study was focused on purification and optimization of amylase from marine actinomycetes. Among 101 actinomycetes isolates from Andaman & Nicobar islands, Streptomyces sp gancidicus_ASD was isolated and further studied. The enzyme activity was studied at various physical parameters like temperature, pH, carbon source, Nitrogen source, metal ions, NaCl concentration etc. by maintaining all the factors with 100 ml of crude extract. Also, media optimization with response surface methodology was used to ameliorate the bioprocess economics. A central composite design was conducted to optimize the four selected factors. Statistical analyses of the data of model fitting were done by using Design expert 10.0 (stat-Ease). Results show a maximum predicted amylase yield of 11460.34 IU/ml when using 1.05% sucrose, 0.608% beef extract, 7.1 pH and 40.35 °C temperature. The predicted value is approximately 1.24-fold much higher than the original production (9248 IU/mL) determined by the conventional one-factor-at-a-time optimization method which can be applied in bioprocess for increased amylase yield

Analysis of Heavy Metals in Edible Jams-A Case Study

Heavy metals are present naturally in relatively low amounts in the earth’s crust. Through food, drinking water and the air, humans absorb trace amounts of these elements. Trace amounts of some heavy metals, such as selenium, zinc, and copper, are key to maintaining the metabolism of the human body. At high concentrations usually found in contaminated environments, such as and contaminated water, heavy metals can cause poisonings resulting in impaired mental and central nervous function, as well as damage to vital organs. Long-term exposure may result in slowly progressing physical, muscular, and neurological degenerative conditions including cancer. Arsenic, cadmium, mercury, lead and inorganic tin account for a majority of heavy metal poisoning cases involving food products. Levels of arsenic are naturally high in fish and seafood. Found in soil due to the presence of insecticides, fungicides, sludge and commercial fertilizers, cadmium can contaminate agricultural food products. Mercury is an industrial pollutant as well as a by-product of volcanic emission. In recent years, a number of products, ranging from protein shakes to baby formula to fresh produce, have been linked to heavy metal contamination. Spurred by consumer calls for safer products, regulatory agencies around the globe are taking steps to detect and minimize the presence of hazardous heavy metals in food. The Food and Drug Administration (FDA) enforces action levels for poisonous or deleterious substances in human food and animal feed, including cadmium, lead, mercury, and others. For most people, diet is the main route of exposure to trace metals, so the assessment risks of these elements to human via dietary intake is important. Cooking jams using fruits, sugar, pectin and edible acids is one of the oldest food preserving processes known to mankind and presents a way of making food stable by increasing the content in soluble solids. In the recent times lots of research findings revealed the presence of deleterious artificial colorants above the permissible levels as well as the heavy metals in sweets, cakes, ice creams etc. Hence Spurred and encouraged by the above reports we authors in our studies analyzed 5 different mixed fruit jam samples of 5 different brands collected from 5 different areas of Bangalore city for some of the heavy metals like Cadmium, Lead, Chromium and Mercury. Our preliminary analysis revealed the minimal permissible levels of all the above mentioned heavy metals in all the 5 different brands which clearly confirms the very presence of the heavy metals at first and secondly also incites a doubt of their usage for human consumption especially for young children who like the very taste of it as to how safe are these Food stuffs contaminated with heavy metals and with carcinogenic artificial food colorants and hence we strongly recommend the Scientific Community to hold a detailed research of these Fruit Jam samples in the near future

Clinicomicrobiological study of the removed intrauterine device

Background: Intrauterine contraceptive devices are one of the most efficient, cost effective long acting reversible contraceptives. But the worrying clinical symptoms, misconceptions and higher rates of genital tract infection have become a hurdle in its acceptance as the first choice of contraception. The objective of this study was to study the common reasons for removal of IUCD.Methods: An observational study was done involving 430 women who reported to the OBG Outpatient of the hospitals attached to Bangalore Medical College, over a period of 2 years, for IUCD removal. Socio-demographic details, clinical symptoms compelling IUCD removal were elicited. The removed IUCD was subjected to culture and sensitivity. Initial descriptive analysis was used and statistical tests of significance like chi-square were used to know the relation between genital infections and IUCD.  P value <0.05 was considered significant.Results: Of the 430 women, 46.9% were between 21-25 years of age, 49.3% were primipara, and 71% used IUCD for 1-3 years. Most common reason for removal in the first 2 years was heavy menstrual bleed followed by pain abdomen. 15.3% culture reports showed growth of bacteria, with maximum cultures positive in <5 years of usage, the association was statistically significant.Conclusions: Present study shows a lower risk of bacterial infections among IUCD users. Hence, effective counseling regarding the safety of IUCD over other spacing methods is essential to increase its acceptance

A CLINICAL OBSERVATIONAL STUDY TO EVALUATE THE COMBINED EFFECT OF DADRUGHNA LEPA AND PITTAKUSTAHARA KASHAYA IN MANAGEMENT OF DADRU (TINEA)

Dadru is one among the Kushta described in the classical text books of Ayurveda which bears greater resemblance with Tinea or Ringworm Infection. It is the commonest single fungus group of infectious skin disorders found in unhygienic conditions of tropical and subtropical countries and most encountered in clinical practice. Unless properly treated they become chronic. Dadru is a disease where all the treatment modalities can be applied as per the requirement of the disease condition. Here in this study, patients diagnosed with Dadru were treated with Dadrughna Lepa externally and Pittaja Kustahara Kashaya internally for a period of 30 days and observations were recorded. Methods: 50 patients fulfilling the diagnostic and inclusion criteria were considered for this single group study of 30 days for each patient. Periodical assessment done during the course of treatment and observations recorded as per case proforma. The data collected during study were Statistical analysed and resultant overall effect of therapy is noted. Results: As a result, Out of 50 patients, highly significant results (p&lt; 0.05) were obtained with respect to Kandu (Itching) (i.e. 75.61%), Raga (Redness)(79.61%), Daha (Burning sensation)(83.12%), Pidaka (Eruption) (84.21%), Rookshata (Dryness)(53.66%), Udgata Mandala (elevated lesion) (71.43%), Size and No. of Lesions (67.82%). Discussion: Out of 50 patients, 2 patients (4%) were getting No improvement, 4 patients (8%) observed to have Mild improvement, 16 patients (32%) were observed with Moderate improvement and 28 patients (56%) with Marked Improvement. Overall effect of the treatment observed is 75.25%

Analysis of caesarean sections according to Robson’s criteria at a tertiary care teaching hospital in central India

Background: The rate of caesarean section (CS) has been skyrocketed globally over the past three decades which makes it utmost essential to be reanalyzed. Hence, the Robson’s classification of international standards has become a need of an hour. This study aimed to analyze the trend of caesarean sections at a tertiary care teaching hospital, by using Robson’s criteria.Methods: This cross-sectional observational study was conducted at Government Medical College in Akola. The data was collected for the women delivered by CS during November 2017 to April 2019 and proportions in various groups as per Robson’s criteria were calculated.Results: The overall CS rate for the study period at our hospital was 63.89%. Robson Group 1 (24.5%) had the greatest representation in the study population followed by Group 5 (21.27%) and 3 (14.18%). While Groups 6 (10.13%) and 9 (0.63%) had the least representation. Group 5 was found to be the highest absolute contributor (20.5%) to overall CS rates followed by Group 1 (16.08%). Group 9 had a least possible share in the study population, but it had 100% CS rate.Conclusions: Robson’s classification must be implemented in all delivery units to avoid unnecessary caesarean sections. Every effort should be made to provide caesarean sections to women in need, rather than striving to achieve a specific rate and Robson’s criteria is a step forward in the same direction

Single Phase PV Microinverter based on Interleaved Flyback Inverter

In this paper, topology of a Grid connected solar microinverter is proposed. The DC power obtained from the solar panel is converted into a rectified AC signal. This conversion is realized by an Active Clamped Flyback Converter. A full-bridge inverter which switched at a high frequency converts this rectified AC into sinusoidal AC of power frequency and this also controls the power flow direction to the grid. The topology is designed and simulated in PSIM software. The designed output values are verified with the simulated result. DOI: 10.17762/ijritcc2321-8169.150517

ANTIPROLIFERATIVE ACTIVITY OF ELEPHANTOPUS SCABER MEDIATED SILVER NANOPARTICLES AGAINST MCF-7, A-549, SCC-40, AND COLO-205 HUMAN CANCER CELL LINES

Objective: To unearth the applications of nanotechnology in medicine has become imperative with all the advancements in the technique. In the current study, we have attempted to exploit the anticancer ability of the green synthesized silver nanoparticles (AgNPs). Methods: The AgNPs were synthesized using 60% methanol (H-MeOH) Elephantopus scaber leaf extract, characterized, and discussed priorly. The effect of AgNPs was studied on the human breast (MCF-7), lung (A-549), oral (SCC-40), and colon (COLO-205) cancer cell lines through sulforhodamine B assay. We also carried out the synergistic activity with standard drug adriamycin (ADR). Results: According to the results obtained, AgNPs showed good antiproliferative activity with GI50 &lt;10 μg/ml on MCF-7, A-549, and SCC-40 cell lines when compared with the standard drug ADR. However, for COLO-205 cell line, the impact was 17.4 μg/ml and thus the treatment was less effective. Conclusion: The synergistic effect of AgNPs+ADR was even better for all the four cell lines than that of the AgNPs alone

Potential anti-seizure activity of atorvastatin in rat models of seizure

Background: Atorvastatin belongs to the class of Hypolipidemic statins. Increasing evidence indicates that statins are neuroprotective in several conditions, including stroke, cerebral ischemia and traumatic brain injury. However, only scanty and controversial reports are available on anticonvulsant action of statins. The present study therefore aims at exploring the influence of atorvastatin on seizures as compared to standard anticonvulsants phenytoin and sodium valproate in Wistar rats.Methods: Rats were divided into 8 groups (n=6), each treated intraperitoneally (i.p) with atorvastatin, phenytoin or sodium valproate in their therapeutic equivalent doses. Their effects were evaluated on seizures induced by maximum electroshock seizure (MES) and pentylenetetrazole (PTZ). Hind limb extension (HLE) in MES model, number of seizures, duration of seizure, number of myoclonic jerks and time for onset as well as recovery from seizures in PTZ model were monitored. Statistical analysis was done using Kruskal-Wallis ANOVA and Mann-Whitney U test for significance.Results: Atorvastatin failed to protect rats against HLE in MES seizure model. However, atorvastatin significantly prolonged seizure onset time (p<0.0547), decreased seizure number (p<0.0082), seizure duration (p<0.0547) and recovery time (p<0.0040) in PTZ model indicating its potential antiepileptic activity in PTZ model.Conclusions: Atorvastatin exhibited protection against seizures only in PTZ seizure model. Hence, it could possess anti absence seizure activity. This needs to be established with further systematic animal and clinical studies