Conclusion of Viking Lander Imaging Investigation: Picture catalog of experiment data record

The images returned by the two Viking landers during the Viking Survey Mission are presented in this report. Listing of supplemental information which describe the conditions under which the images were acquired are included. Subsets of the images are listed in a variety of sequences to aid in locating images of interest. The format and organization of the digital magnetic tape storage of the images are described. A brief description of the mission and the camera system is also included

Suppression of erythropoiesis by dietary nitrate.

In mammals, hypoxia-triggered erythropoietin release increases red blood cell mass to meet tissue oxygen demands. Using male Wistar rats, we unmask a previously unrecognized regulatory pathway of erythropoiesis involving suppressor control by the NO metabolite and ubiquitous dietary component nitrate. We find that circulating hemoglobin levels are modulated by nitrate at concentrations achievable by dietary intervention under normoxic and hypoxic conditions; a moderate dose of nitrate administered via the drinking water (7 mg NaNO₃/kg body weight/d) lowered hemoglobin concentration and hematocrit after 6 d compared with nonsupplemented/NaCl-supplemented controls. The underlying mechanism is suppression of hepatic erythropoietin expression associated with the downregulation of tissue hypoxia markers, suggesting increased pO₂. At higher nitrate doses, however, a partial reversal of this effect occurred; this was accompanied by increased renal erythropoietin expression and stabilization of hypoxia-inducible factors, likely brought about by the relative anemia. Thus, hepatic and renal hypoxia-sensing pathways act in concert to modulate hemoglobin in response to nitrate, converging at an optimal minimal hemoglobin concentration appropriate to the environmental/physiologic situation. Suppression of hepatic erythropoietin expression by nitrate may thus act to decrease blood viscosity while matching oxygen supply to demand, whereas renal oxygen sensing could act as a brake, averting a potentially detrimental fall in hematocrit.This work was supported by British Heart Foundation Studentship FS/09/050 (to T.A.). A.J.M. thanks the Research Councils UK for supporting his academic fellowship and the WYNG Foundation of Hong Kong for support. J.L.G is supported by the European Union Framework 7 Inheritance project, R.S.J. is supported by a Wellcome Trust Principal research fellowship, and M.F. is supported by funds from the Faculty of Medicine, University of Southampton

Macromolecular and electrical coupling between inner hair cells in the rodent cochlea

Inner hair cells (IHCs) are the primary receptors for hearing. They are housed in the cochlea and convey sound information to the brain via synapses with the auditory nerve. IHCs have been thought to be electrically and metabolically independent from each other. We report that, upon developmental maturation, in mice 30% of the IHCs are electrochemically coupled in ‘mini-syncytia’. This coupling permits transfer of fluorescently-labeled metabolites and macromolecular tracers. The membrane capacitance, Ca2+-current, and resting current increase with the number of dye-coupled IHCs. Dual voltage-clamp experiments substantiate low resistance electrical coupling. Pharmacology and tracer permeability rule out coupling by gap junctions and purinoceptors. 3D electron microscopy indicates instead that IHCs are coupled by membrane fusion sites. Consequently, depolarization of one IHC triggers presynaptic Ca2+-influx at active zones in the entire mini-syncytium. Based on our findings and modeling, we propose that IHC-mini-syncytia enhance sensitivity and reliability of cochlear sound encoding

A New Gauge for Computing Effective Potentials in Spontaneously Broken Gauge Theories

A new class of renormalizable gauges is introduced that is particularly well suited to compute effective potentials in spontaneously broken gauge theories. It allows one to keep free gauge parameters when computing the effective potential from vacuum graphs or tadpoles without encountering mixed propagators of would-be-Goldstone bosons and longitudinal modes of the gauge field. As an illustrative example several quantities are computed within the Abelian Higgs model, which is renormalized at the two-loop level. The zero temperature effective potential in the new gauge is compared to that in $R_\xi$ gauge at the one-loop level and found to be not only easier to compute but also to have a more convenient analytical structure. To demonstrate renormalizability of the gauge for the non-Abelian case, the renormalization of an SU(2)-Higgs model with completely broken gauge group and of an SO(3)-Higgs model with an unbroken SO(2) subgroup is outlined and renormalization constants are given at the one-loop level.Comment: 24 pages, figures produced by LaTeX, plain LaTeX, THU-93/16. (Completely revised. Essential changes. New stuff added. To appear in Phys.Rev.D.

From arbitrariness to ambiguities in the evaluation of perturbative physical amplitudes and their symmetry relations

A very general calculational strategy is applied to the evaluation of the divergent physical amplitudes which are typical of perturbative calculations. With this approach in the final results all the intrinsic arbitrariness of the calculations due to the divergent character is still present. We show that by using the symmetry properties as a guide to search for the (compulsory) choices in such a way as to avoid ambiguities, a deep and clear understanding of the role of regularization methods emerges. Requiring then an universal point of view for the problem, as allowed by our approach, very interesting conclusions can be stated about the possible justifications of most intriguing aspect of the perturbative calculations in quantum field theory: the triangle anomalies.Comment: 16 pages, no figure

Decays of Scalar and Pseudoscalar Higgs Bosons into Fermions: Two-loop QCD Corrections to the Higgs-Quark-Antiquark Amplitude

As a first step in the aim of arriving at a differential description of neutral Higgs boson decays into heavy quarks, $h \to Q {\bar Q}X$, to second order in the QCD coupling $\alpha_S$, we have computed the $hQ{\bar Q}$ amplitude at the two-loop level in QCD for a general neutral Higgs boson which has both scalar and pseudoscalar couplings to quarks. This amplitude is given in terms of a scalar and a pseudoscalar vertex form factor, for which we present closed analytic expressions in terms of one-dimensional harmonic polylogarithms of maximum weight 4. The results hold for arbitrary four-momentum squared, $q^2$, of the Higgs boson and of the heavy quark mass, $m$. Moreover we derive the approximate expressions of these form factors near threshold and in the asymptotic regime $m^2/q^2 \ll 1$.Comment: 56 pages, 2 figure

Anomalous Commutator Algebra for Conformal Quantum Mechanics

The structure of the commutator algebra for conformal quantum mechanics is considered. Specifically, it is shown that the emergence of a dimensional scale by renormalization implies the existence of an anomaly or quantum-mechanical symmetry breaking, which is explicitly displayed at the level of the generators of the SO(2,1) conformal group. Correspondingly, the associated breakdown of the conservation of the dilation and special conformal charges is derived.Comment: 23 pages. A few typos corrected in the final version (which agrees with the published Phys. Rev. D article

Gauge and parametrization dependencies of the one-loop counterterms in the Einstein gravity.

The parametrization and gauge dependencies of the one-loop counterterms on the mass-shell in the Einstein gravity are investigated. The physical meaning of the loop calculation results on the mass shell and the parametrization dependence of the renormgroup functions in the nonrenormalizable theories are discussed.Comment: 14 pages in LATEX (Some references added

On-shell two-loop three-gluon vertex

The two-loop three-gluon vertex is calculated in an arbitrary covariant gauge, in the limit when two of the gluons are on the mass shell. The corresponding two-loop results for the ghost-gluon vertex are also obtained. It is shown that the results are consistent with the Ward-Slavnov-Taylor identities.Comment: 34 pages, LaTeX, including 5 figures, uses eps

Explicit results for all orders of the epsilon-expansion of certain massive and massless diagrams

An arbitrary term of the epsilon-expansion of dimensionally regulated off-shell massless one-loop three-point Feynman diagram is expressed in terms of log-sine integrals related to the polylogarithms. Using magic connection between these diagrams and two-loop massive vacuum diagrams, the epsilon-expansion of the latter is also obtained, for arbitrary values of the masses. The problem of analytic continuation is also discussed.Comment: 8 pages, late