322 research outputs found

    Flexible aircraft flying and ride qualities

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    A brief analytic exposition is presented to illustrate a central principle in flexible mode control, some of the pertinent pilot centered requirements are listed and discussed. The desired features of the control methodology are exposed and the methodology to be used is selected. The example Boeing supplied characteristics are discussed and approximated with a reduced order model and a simplified treatment of unsteady aerodynamics. The closed loop flight control system design follows, along with first level assessments of resulting handling and ride quality characteristics. Some of these do not meet the postulated requirements and remain problems to be solved possibly by further analysis or future simulation

    Analyses of shuttle orbiter approach and landing conditions

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    A study of one shuttle orbiter approach and landing conditions are summarized. Causes of observed PIO like flight deficiencies are identified and potential cures are examined. Closed loop pilot/vehicle analyses are described and path/attitude stability boundaries defined. The latter novel technique proved of great value in delineating and illustrating the basic causes of this multiloop pilot control problem. The analytical results are shown to be consistent with flight test and fixed base simulation. Conclusions are drawn relating to possible improvements of the shuttle orbiter/digital flight control system

    Flight dynamics analysis and simulation of heavy lift airships. Volume 1: Executive summary

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    A generic, yet comprehensive mathematical model and computer simulation of the HLA flight dynamics over its entire flight envelope was developed. Implicit in this simulation development are the data reviews and analyses which support the equations of motion and the calculation of forces and moments acting on the vehicle. The simulation, HYBRDS, is addressed to the broad requirements and is intended for use as a synthesis and analysis tool for the evaluation of competing HLA design concepts

    Flight dynamics analysis and simulation of heavy lift airships. Volume 5: Programmer's manual

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    The Programmer's Manual contains explanations of the logic embodied in the various program modules, a dictionary of program variables, a subroutine listing, subroutine/common block/cross reference listing, and a calling/called subroutine cross reference listing

    Mission-oriented requirements for updating MIL-H-8501. Volume 1: STI proposed structure

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    The structure of a new flying and ground handling qualities specification for military rotorcraft is presented. This preliminary specification structure is intended to evolve into a replacement for specification MIL-H-8501A. The new structure is designed to accommodate a variety of rotorcraft types, mission flight phases, flight envelopes, and flight environmental characteristics and to provide criteria for three levels of flying qualities, a systematic treatment of failures and reliability, both conventional and multiaxis controllers, and external vision aids which may also incorporate synthetic display content. Existing and new criteria were incorporated into the new structure wherever they could be substantiated

    Agent based modelling helps in understanding the rules by which fibroblasts support keratinocyte colony formation

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    Background: Autologous keratincoytes are routinely expanded using irradiated mouse fibroblasts and bovine serum for clinical use. With growing concerns about the safety of these xenobiotic materials, it is desirable to culture keratinocytes in media without animal derived products. An improved understanding of epithelial/mesenchymal interactions could assist in this. Methodology/Principal Findings: A keratincyte/fibroblast o-culture model was developed by extending an agent-based keratinocyte colony formation model to include the response of keratinocytes to both fibroblasts and serum. The model was validated by comparison of the in virtuo and in vitro multicellular behaviour of keratinocytes and fibroblasts in single and co-culture in Greens medium. To test the robustness of the model, several properties of the fibroblasts were changed to investigate their influence on the multicellular morphogenesis of keratinocyes and fibroblasts. The model was then used to generate hypotheses to explore the interactions of both proliferative and growth arrested fibroblasts with keratinocytes. The key predictions arising from the model which were confirmed by in vitro experiments were that 1) the ratio of fibroblasts to keratinocytes would critically influence keratinocyte colony expansion, 2) this ratio needed to be optimum at the beginning of the co-culture, 3) proliferative fibroblasts would be more effective than irradiated cells in expanding keratinocytes and 4) in the presence of an adequate number of fibroblasts, keratinocyte expansion would be independent of serum. Conclusions: A closely associated computational and biological approach is a powerful tool for understanding complex biological systems such as the interactions between keratinocytes and fibroblasts. The key outcome of this study is the finding that the early addition of a critical ratio of proliferative fibroblasts can give rapid keratinocyte expansion without the use of irradiated mouse fibroblasts and bovine serum
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