Evaluation of Groundwater Suitability for Irrigation in the Lambussie-Karni District of Ghana

The populace of the Lambussie-Karni District are mainly farmers who have resorted to the use of groundwater for irrigation during the dry season because of long drought and inadequate surface water bodies. The temporal variation of the groundwater quality for irrigation in the District was assessed using sixteen boreholes. Richard Plot indicates that groundwater in the study area is within the low salinity to low sodium hazard and medium salinity to low sodium hazard class. Wilcox Plot shows groundwater to be within excellent to good class in the catchment. Irrigation water quality index (IWQI) map was also developed to determine precisely the degree and areal extent of groundwater suitability for irrigation. ArcGIS 10.1 was used to generate thematic maps for sodium adsorption ratio (SAR), residual sodium carbonate (RSC), permeability index (PI), sodium percentage (Na %), HCO3-, pH and electrical conductivity. The results were compared to Food and Agricultural Organisations (FAO) standard guidelines. An IQWI map for the Lambussie- Karni District shows that groundwater is generally suitable for irrigation, about 24.57 % of the district will require crops which can tolerate high amount of salts. A percentage (39.82 %) of the catchment has groundwater, which is highly suitable for crops which are least resistant to salt. Keywords: Groundwater Suitability; Irrigation Water Quality; SAR; IWQI Map; Lambussie-Karni Distric

Testing for Randomness in Pseudo Random Number Generators Algorithms in a Cryptographic Application

The most effective cryptographic algorithm has more randomness in the numbers a generator generates, and the more secured it is to be used for protecting confidential data. Sometimes developers find it difficult to determine which Random Number Generators (RNGs) can provide a much secured Cryptographic System for secured enterprise application implementations. This research aims to find an effective Pseudo Random Number Generator algorithm among Fibonacci Random Numbers Generator Algorithms, Gaussian Random Numbers Generator Algorithm, Specific Range Random Numbers Generator Algorithms, and Secure Random numbers Generators, which are the most common Pseudo Random Numbers Generators Algorithms, that can be used to improve the security of Cryptographic software systems. The researchers employed Chi-Square test on the first 100 random numbers between 0 to 1000 generated using the above generators and it concluded that, Fibonacci Random Numbers Generator Algorithms can provide a more secured cryptographic application. Keywords Pseudo Random Number Generators, Randomness, Cryptography, Softwar

Evaluation of the Food and Drugs Authority, Ghana Regulatory Review Process: Challenges and Opportunities

© The Author(s) 2022. This article is licensed under a Creative Commons Attribution 4.0 International License,. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.Purpose: This study aimed to assess the current regulatory review process of the food and drugs authority (FDA) Ghana by identifying key milestones, target timelines, good review practices and quality decision-making practices and evaluating the overall regulatory performance from 2019 to 2021, as well as the challenges and opportunities for improvement. Methods: The FDA Ghana representatives completed the optimising efficiencies in regulatory agencies (OpERA) questionnaire, including data identifying the milestones and overall approval times for all products registered by the FDA Ghana from 2019 to 2021. Results: Of the new active substances approved from 2019 to 2021, 91% were biologicals processed by full or abridged reviews pathways. Timelines for these reviews were within authority targets but were longer compared with generics. Of generics approved from 2019 to 2021, 97% were pharmaceuticals processed by the full review pathway, with timelines within authority targets and shorter compared with new active substances. Regardless of the review model used, approval times for new active substances increased from 84 to 355 calendar days 2019–2021 due to the impact of the pandemic. Guidelines, standard operating procedures and review templates were in place and the majority of indicators for good review practices were implemented. Several quality decision-making practices were implemented, although currently there is not a systematic structured approach. Conclusion: The FDA Ghana monitors regulatory performance and currently meets its target timelines. To achieve World Health Organization Maturity Level 4 status, an electronic tracking system, benefit-risk assessment framework and template and the publication of assessment reports are recommended.Peer reviewe

Nutritional Status of Boarding and Non-Boarding Children in Selected Schools in the Accra Metropolis

Malnutrition is highly prevalent in developing countries. Children are at high nutritional risk of being malnourished because of their physiological demands at this age. However, the nutritional status of school age children is poorly documented in Ghana. The aim of this study was to assess and compare the nutritional status of boarding and non-boarding pupils aged 8 to 10 years in the Accra Metropolis, Ghana. A cross-sectional study was conducted among 124 children in three private schools which have boarding facilities (optional) in the Accra Metropolis, Ghana. Dietary intakes of children between the ages of 8 and 10 years were assessed using a two-day 24 hour recall.  Weight and height measurements were taken. WHO Anthroplus software was used to determine WAZ, HAZ and BAZ. Ghanaian food composition tables were used to calculate the nutritional components of foods eaten by subjects. T-tests were used to analyse differences between variables. The prevalence of stunting, underweight, overweight and obesity among the children were 0.8%, 0.8%, 12.1% and 11.3% respectively. The total energy and nutrient intake of calcium among children (both boarders and non-boarders) was inadequate. There was no significant difference in the nutritional status and mean nutrient intake between boarding and non-boarding children. Nutritional status between boarders and non boarders were found to be similar. Key words: School children, boarders, non-boarders, Ghanaian, nutritional statu

Land Use / Land Cover Change And Impact On Carbon Stocks In The Atacora Chain Of Mountains, A Biodiversity Hotspot In Benin (West Africa)

Mountain areas are fragile ecosystems that play important roles in people’s livelihoods and maintenance of the global ecosystem through the provision of many ecosystem services. Land use/cover (LULC) change is considered one of the major threats to mountain areas due to its effects on ecosystem services including carbon stocks. In this study we assessed LULC change between 1987 and 2015 and its impact on aboveground carbon stocks in the Atacora Chain of Mountains (ACM) in Benin, West Africa. Supervised classification was performed to delineate LULC classes on three dates (1987, 2001 and 2015), and forest measurements carried out in the land cover classes, to estimate the aboveground biomass and the subsequent carbon stocks. Seven land cover classes were delineated: gallery forests, woodlands, savanna, water, settlements, bare lands and farm lands. LULC changes were characterized by three transitions: 1) the change of man-made land cover into savanna, 2) the change of natural vegetation into man-made land cover and 3) the degradation of gallery forests and woodland into less wooded vegetation. The aboveground carbon stock in gallery forests, woodland and tree savanna were significantly greater than in shrub savanna. During the 28 years of assessment, LULC change in gallery forests, woodland and savanna caused an estimated overall aboveground carbon release of 17.10% in the ACM. From the aboveground carbon quantity in the ACM, it appeared that this ecosystem is a potential carbon reservoir. Because the aboveground carbon stock in shrub savanna is significantly lower as compared to gallery forests, woodland and tree savanna and the rates of degradation from gallery forests and woodland to savanna are high, 53.62% and 59.99% respectively in 28 years, LULC change may undermine the ACM ability to store carbon and contribute to climate change mitigation. There is a need to investigate the drivers of this degradation for actions to preserve the natural vegetation in the ACM. Keywords: Atacora Chain of Mountains; Land use/land cover (LULC); Benin; West Africa; Carbon stock DOI: 10.7176/JEES/10-6-13 Publication date:June 30th 202

Built-in premium effects within exotic FX options

Purpose: This paper explains the analysis of built-in premium within ‘premium-free’ FX Option strategies, also known as ‘exotic options’. The aim is to analyse whether such an increase in built-in premium would have an effect on the outcome of the strategies. Methodology: The analysis was conducted through three different currency pairs, namely, the EURUSD, EURJPY and EURGBP, throughout a period between 2007 to 2014. The authors used the Bloomberg terminal to design two different option strategies: Window Forward Extra and At Expiry Forward Extra. These strategies are known as low risk hedging strategies within the FX options industry. The authors examined different combinations of changes in built-in premium and analysed the respective outcome with each combination. The outcomes were compared to analyse whether an increase in built-in premium would have an effect on the outcome of the strategy. A test was also conducted should these strategies be used as a speculative tool. The strategies were built on a 1 year tenor which is rolled over every month. Hence, each month a hedge using the strategy for 1 year was conducted. The authors used back dated implied volatilies when performing the back-testing in order for results to be realistic. Findings: In most cases it was found that there was no effect on the outcome of the strategy. However, this was only valid if an expiry at a time is taken. On the other hand, when taking into account the whole sample, even though only 3% of the times there was an effect on the outcome of the strategy, the total result finds that an increase in built-in premium has an effect on the outcome of the strategy. Such result was found to be statistically significant using a paired sample t-test. This applied for all currency pairs under review. When analysing the exotic option strategies for speculative purposes, the authors found that in most cases it would have been better for brokers to take higher risk and receive an upfront Premium.peer-reviewe

A typical presentation of COVID-19 in a patient with type 2 diabetes at an urban primary care facility in Accra, Ghana

This is a case report of a 55-year-old man with Type 2 Diabetes Mellitus who presented with progressive breathlessness, chest pain and hyperglycaemia. An initial impression of a chest infection was made. Management was initiated with antibiotics, but this was unsuccessful, and he continued to desaturate. A screen for Coronavirus Disease of 2019 (COVID-19) returned positive. There was no prodrome of fever or flu-like illness or known contact with a patient known to have COVID-19. This case is instructive as he didn’t fit the typical case definition for suspected COVID-19. There is significant community spread in Ghana, therefore COVID-19 should be a differential diagnosis in patients who present with hyperglycaemia and respiratory symptoms in the absence of a febrile illness. Primary care doctors must have a high index of suspicion in cases of significant hyperglycaemia and inability to maintain oxygen saturation.Patients known to have diabetes and those not known to have diabetes may develop hyperglycaemia subsequent to COVID-19. A high index of suspicion is crucial for early identification, notification for testing, isolation, treatment, contact tracing and possible referral or coordination of care with other specialists. Early identification will protect healthcare workers and patients alike from cross-infection

Plant & its Bioactive Components Uses in Cardio-Potential Diseases: A Sectional Study for Different Herbs

Thirty percent of all deaths that occur each year can be attributed to heart disease, stroke, and other forms of cardiovascular disease. The World Health Organisation (WHO) predicts that by the year 2030, the annual death toll from cardiovascular diseases will have increased to 22.2 million, up from the present annual total of 17.9 million. Mortality rates tend to go up in populations as they get older. The chance of dying from cardiovascular disease is significantly higher for females (51%) than it is for males (42%). The majority of people treat and prevent cardiovascular disease by using plant-based medications (also known as phytochemicals), either in addition to or in instead of pharmaceuticals that are readily available on the market. In this study, the efficacy of treating cardiovascular illness is evaluated using 92 different plants, including 15 terrestrial plants. A number of different medicinal herbs, including Daucus carota, Nerium oleander, Amaranthus Viridis, Ginkgo biloba, Terminalia arjuna, Picrorhiza kurroa, Salvia miltiorrhiza, Tinospora cordifolia, Mucuna pruriens, Hydrocotyle asiatica, Bombax ceiba, and Andrographis paniculate, are utilised to treat cardiovascular disease. There are a variety of active phytochemicals found in these plants, some of which include flavonoids, polyphenols, plant sterols, plant sulphur compounds, and terpenoids. Flavonoids, in general, are known to increase vasodilation by inhibiting the oxidation of low-density lipoprotein (LDL). Plant sterols reduce the amount of cholesterol in the blood, which in turn protects against cardiovascular disease. Plant sulphur compounds protect against cardiovascular disease in addition to their role in the activation of nuclear factor-erythroid factor 2-related factor 2 (Nrf2) and the inhibition of cholesterol formation. The incidence of cardiovascular disease can be reduced by increasing the synthesis of ATP in mitochondria, and terpenoids can diminish atherosclerotic lesion in the aortic valve. Even though several physiologically active compounds with acknowledged biological functions have been found in a wide variety of plants, the prevalence of cardiovascular disease continues to rise, making it imperative that effective CVD prevention and treatment strategies be developed. More research is required to understand both the mechanism and the individual phytochemicals in plants that treat CVD. GRAPHICAL ABSTRAC

Protracted cholera outbreak in the Central Region, Ghana, 2016

Objective: On 24th October 2016, the Central Regional Health Directorate received report of a suspected cholera outbreak in the Cape Coast Metropolis (CCM). We investigated to confirm the diagnosis, identify risk factors and implement control measures.Design: We used a descriptive study followed by 1:2 unmatched case-control study.Data source: We reviewed medical records, conducted active case search and contact tracing, interviewed case-patients and their contacts and conducted environmental assessment. Case-patients' stool samples were tested with point of care test kits (SD Bioline Cholera Ag 01/0139) and sent to the Cape Coast Teaching Hospital Laboratory for confirmation.Main outcomes: Cause of outbreak, risk factors associated with spread of outbreakResults: Vibrio cholerae serotype Ogawa caused the outbreak. There was no mortality. Of 704 case-patients, 371(52.7%) were males and 55(7.8%) were aged under-five years. The median age was 23 years (interquartile range: 16-32 years). About a third 248(35.2%) of the case patients were aged 15-24 years. The University of Cape Coast subdistrict was the epicenter with 341(48.44%) cases. Compared to controls, cholera case-patients were more likely to have visited Cholera Treatment Centers (CTC) (aOR=12.1, 95%CI: 1.5-101.3), drank pipe-borne water (aOR=11.7, 95%CI: 3.3-41.8), or drank street-vended sachet water (aOR=11.0, 95%CI: 3.7-32.9). Open defecation and broken sewage pipes were observed in the epicenter.Conclusion: Vibrio cholerae serotype Ogawa caused the CCM cholera outbreak mostly affecting the youth. Visiting CTC was a major risk factor. Prompt case-management, contact tracing, health education, restricting access to CTC and implementing water sanitation and hygiene activities helped in the control.Keywords: Cholera outbreak, Vibrio cholerae serotype Ogawa, Cholera treatment center, Water sanitation and hygiene, Cape Coast MetropolisFunding: This work was supported by Ghana Field Epidemiology and Laboratory Training Program (GFELTP), University of Ghan