Cardiovascular Risk Factors Among People being Treated for HIV in Nepal: a Cross-Sectional Study.

Background: Human Immunodeficiency Virus (HIV) and antiretroviral therapy (ART) are found to be strongly associated with cardiovascular diseases. Data are sparse on the prevalence and distribution of cardiovascular risk factors among people being treated for HIV in South Asia region. Methods: A cross-sectional study of 103 HIV patients (51 women and 52 men) attending routine follow-up consultations at the largest ART centre in Nepal was conducted. Data on several cardiovascular risk factors were collected through interview questionnaires, biophysical measurements and consulting medical records. Results: The most common cardiovascular risk factors observed were central obesity [34.6%, 95% Confidence Interval (CI): 25.3% to 43.9%], chronic kidney disease [20.7% (95% CI: 11.6% to 29.7%)] and tachycardia [20.6% (95% CI: 12.7% to 28.5%)]. Females were significantly more likely to have central obesity (male 9.8% vs. female 60%, p=0.016) and chronic kidney disease (male 15.4% vs. female 26.3%, p=0.003) as compared to the males. Participants were fairly active but a large proportion, especially men, had smoked [65% (95% CI: 57%-72.3%)], used tobacco products [66% (95% CI: 56.4%-74.4%)] or drugs (53.8% of the men) and consumed alcohol [60.2% (95% CI: 50.5%-69.1%)]. Conclusion: A high prevalence of several cardiovascular risk factors was observed among patients being treated for HIV in Nepal. Further larger studies are warranted to better understand the relevance and public health impact of cardiovascular risk factors in this region

Application of the Truncated Skew Laplace Probability Distribution in Maintenance System

A random variable X is said to have the skew-Laplace probability distribution if its pdf is given by f(x) = 2g(x)G(λx), where g (.) and G (.), respectively, denote the pdf and the cdf of the Laplace distribution. When the skew Laplace distribution is truncated on the left at 0 it is called it the truncated skew Laplace (TSL) distribution. This article provides a comparison of TSL distribution with twoparameter gamma model and the hypoexponential model, and an application of the subject model in maintenance system is studied

Adoption of Goat Production Technology and Its Impact Among Rural Farmers in Nawalparsi District of Nepal

Nayabelhani VDC of Nawalparasi district was chosen to judge the effectiveness of goat production technology supported by Heifer International Nepal. Field survey with before and after approach was employed in the study. Information obtained from Stratified random sampling technique from 90 households with structured questionnaire and was compared with the baseline data. Adoption index was calculated through scoring technique after content validation. Participatory rural appraisal for problems identification. The research revealed that the extent of adoption of scientific goat production technology after project was higher than before project (80% Vs 32%, P<0.01). Further, the average herd size after the project was slightly decreased from 6.585 to 5.677 while the kid mortality dropped from 15% to 11%. The average number of kidding in 2 years was increased from 2 to 3 and the average number of kids per kidding was increased from 1 to 2. Goats were more frequently marketed at an average age of 12 months with an average weight of 24kg after the project. Similarly, the average annual income from the goat per household was found to be almost doubled from Nrs. 8,489 to Nrs. 15,084. Predator was found to be the most serious problem out of seven identified problems

Neck shrivel in European plum is caused by cuticular microcracks, resulting from rapid lateral expansion of the neck late in development

Susceptibility to the commercially important fruit disorder ‘neck shrivel’ differs among European plum cultivars. Radial cuticular microcracking occurs in the neck regions of susceptible cultivars, but not in non-susceptible ones, so would seem to be causal. However, the reason for the microcracking is unknown. The objective was to identify potential relationships between fruit growth pattern and microcracking incidence in the neck (proximal) and stylar (distal) ends of selected shrivel-susceptible and non-susceptible cultivars. Growth analysis revealed two allometric categories: The first category, the ‘narrow-neck’ cultivars, showed hypoallometric growth in the neck region (i.e., slower growth than in the region of maximum diameter) during early development (stages I + II). Later (during stage III) the neck region was ‘filled out’ by hyperallometric growth (i.e., faster than in the region of maximum diameter). The second category, the ‘broad-neck’ cultivars, had more symmetrical, allometric growth (all regions grew equally fast) throughout development. The narrow-neck cultivars exhibited extensive radial cuticular microcracking in the neck region, but little microcracking in the stylar region. In contrast, the broad-neck cultivars exhibited little microcracking overall, with no difference between the neck and stylar regions. Across all cultivars, a positive relationship was obtained for the level of microcracking in the neck region and the difference in allometric growth ratios between stage III and stages I + II. There were no similar relationships for the stylar region. The results demonstrate that accelerated stage III neck growth in the narrow-neck plum cultivars is associated with more microcracking and thus with more shrivel

Agro-morphological Diversity of High Altitude Bean Landraces in the Kailash Sacred Landscape of Nepal

Many varieties of bean are widely grown across diverse agro-ecological zones in Nepal. And opportunities exist for improving the crops and enhancing their resilience to various biotic and abiotic stressors. In this context, an experiment was conducted from June to October 2016 in Khar VDC of Darchula district to study the phenotypic traits of nine landraces of bean (Phaseolus vulgaris L.). The bean landraces were planted using randomized complete block design in three sites (Dhamidera, Dallekh and Sundamunda villages), with three replications in each site for their comparative analysis. The study considered the following phenotypic traits: days to emergence, days to 50% flowering, days to 90% pod maturity, number of nodes, pod length, pod width, number of pods, number of seeds per pod and weight and grain yield for 100 seeds. Kruskal-Wallis test showed significant differences in the landraces both within and among locations. KA-17-08-FB and KA-17-04-FB were late  flowering (63 and 65 days respectively) compared to other landraces whereas KA-17-07-FB flowered earliest (within 42 days). In all three sites, three landraces namely KA-17-07-FB, KA-17-04-FB and KA-17-06-FB were found to be relatively more resistant to pest and diseases than other landraces. Eight out of nine landraces in Dhamidera and Dallekh villages and seven out of nine in Sundamunda village produced seeds greater than 1.0 t/ha. Among the nine varieties KA-17-02-FB was the highest yielding variety, with an average yield of 3.8 t/ha. This study is useful for identifying suitable landraces for future promotion based on their maturity, grain yield, diseases resistance and other qualitative and quantitative characteristics

CONSERVATION THROUGH UTILISATION: AN ANALYSIS OF INDIGENOUS PEOPLE’S DEPENDENCY ON FOREST RESOURCES FOR LIVELIHOOD SUPPORT IN THE MIDDLE HILLS OF NEPAL

The principle aim of this paper was to analyze the richness, status and contribution of uncultivated plants for the livelihoods of two indigenous ethnic groups of Nepal. The uncultivated plants are used for foods, medicines, and for cultural and economical reasons. Initially, exploratory techniques such as diversity fairs, key informant interviews and group discussions were conducted, followed by more detailed household surveys. A total of 105 households (62 in Dhading and 43 in Kaski) were included. Altogether 112 plant species were documented; including 61 species with multiple functions as food, vegetables, and medicines. The highest richness of uncultivated plants (99) was found in the forest environments. Uncultivated foods contributed significantly to food requirements and filled the gap of about 2 months per year. More than 58% of the households in Dhading use these resources at least 3.5 months a year compared to 5% in Kaski. Many species have large cultural importance and are important source of local medicines. The availability of these resources has been declining over time. However, people have started conservation and management initiatives. The uncultivated plant species are crucial to both ethnic groups, but are neglected by authorities

Thorny Spheres and Black Holes with Strings

We consider thorny spheres, that is 2-dimensional compact surfaces which are everywhere locally isometric to a round sphere $S^2$ except for a finite number of isolated points where they have conical singularities. We use thorny spheres to generate, from a spherically symmetric solution of the Einstein equations, new solutions which describe spacetimes pierced by an arbitrary number of infinitely thin cosmic strings radially directed. Each string produces an angle deficit proportional to its tension, while the metric outside the strings is a locally spherically symmetric solution. We prove that there can be arbitrary configurations of strings provided that the directions of the strings obey a certain equilibrium condition. In general this equilibrium condition can be written as a force-balance equation for string forces defined in a flat 3-space in which the thorny sphere is isometrically embedded, or as a constraint on the product of holonomies around strings in an alternative 3-space that is flat except for the strings. In the case of small string tensions, the constraint equation has the form of a linear relation between unit vectors directed along the string axes.Comment: 37 pages, 11 figure

New Country Records and Annotated Checklist of the Dacine Fruit Flies (Diptera: Tephritidae: Dacini) of Nepal

Preliminary surveys for Dacine fruit flies were carried out in May 2015 and June 2017, with male lure (cue-lure, methyl eugenol, zingerone) traps maintained at 55 sites, (110–1,780 m elevation range), comprised mostly of Nepal Agricultural Research Council research stations. Twenty species were collected, including 11 new country occurrence and 2 new male lure association records. The most common species were fruit pests Bactrocera dorsalis (60.4% of all captures) and B. zonata (15.2%), and cucurbit pests Zeugodacus tau (9.5%) and Z. cucurbitae (8.7%). We present an annotated checklist of the 26 species now known to occur in Nepal, including 5 fruit and 6 cucurbit pests

In Situ and Ex Situ Studies of Molybdenum Thin Films Deposited by rf and dc Magnetron Sputtering as a Back Contact for CIGS Solar Cells

Molybdenum thin films were deposited by rf and dc magnetron sputtering and their properties analyzed with regards to their potential application as a back contact for CIGS solar cells. It is shown that both types of films tend to transition from tensile to compressive strain when the deposition pressure increases, while the conductivity and the grain size decreas. The nucleation of the films characterized by in situ and real time spectroscopic ellipsometry shows that both films follow a Volmer-Weber growth, with a higher surface roughness and lower deposition rate for the rf deposited films. The electronic relaxation time was then extracted as a function of bulk layer thickness for rf and dc films by fitting each dielectric function to a Drude free-electron model combined with a broad Lorentz oscillator. The values were fitted to a conical growth mode and demonstrated that the rf-deposited films have already smaller grains than the dc films when the bulk layer thickness is 30 nm