Final Report: Wall Effects in Cavity Flows

The wall effects in cavity flows past an arbitrary two-dimensional body is investigated for both pure-drag and lifting cases based on an inviscid nonlinear flow theory. The over-all features of various theoretical flow models for inviscid cavity flows under the wall effects are discussed from the general momentum consideration in comparison with typical viscous, incompressible wake flows in a channel. In the case of pure drag cavity flows, three theoretical models in common use, namely, the open-wake, Riabouchinsky and re-entrant jet models, are applied to evaluate the solution. Methods of numerical computation are discussed for bodies of arbitrary shape, and are carried out in detail for wedges of all angles. The final numerical results are compared between the different flow models, and the differences pointed out. Further analysis of the results has led to development of several useful formulas for correcting the wall effect. In the lifting flow case, the wall effect on the pressure and hydrodynamic forces acting on arbitrary body is formulated for the choked cavity flow in a closed water tunnel of arbitrary shape, and computed for the flat plate with a finite cavity in a straight tunnel

Foundations of character: methodological aspects of a study of character development in three- to six-year-old children with a focus on sharing behaviours

This article focuses on methodological issues arising in a study of character development, using illustrations of ‘sharing behaviours.’ Based primarily in six early years settings in southeast England the research records naturalistic observations of peer interactions for 55 children aged three to six years. Applying grounded theory to the processes of observing, analysing and interpreting evidence required a cautious and collectively reflective approach. The methodology sought to moderate the influence of the researchers' prior knowledge of ‘grand theories’ of moral development and assumptions about relevance to the observation records. The study's originality lay in the exploration of moral development without reference to any particular grand theory as an explanatory framework; and in the reluctance to be drawn to potentially simplistic rationalisations of the children's intentions on the basis of their observed behaviours. Exploring young children's subjective experiences, this research provides insights into the intricacy of this process, steering away from ‘neat’ findings and attempting to reflect the sophistication of the children's skilful and sometimes surprising negotiations of moral dilemmas. Implications for practice relate to the complexities involved in attempts to unravel the developing moral characters of young children and the practice through which this may be nurtured

Merging multiple-partial-depth data time series using objective empirical orthogonal function fitting

Author Posting. © IEEE, 2010. This article is posted here by permission of IEEE for personal use, not for redistribution. The definitive version was published in IEEE Journal of Oceanic Engineering 35 (2010): 710-721, doi:10.1109/JOE.2010.2052875.In this paper, a method for merging partial overlapping time series of ocean profiles into a single time series of profiles using empirical orthogonal function (EOF) decomposition with the objective analysis is presented. The method is used to handle internal waves passing two or more mooring locations from multiple directions, a situation where patterns of variability cannot be accounted for with a simple time lag. Data from one mooring are decomposed into linear combination of EOFs. Objective analysis using data from another mooring and these patterns is then used to build the necessary profile for merging the data, which is a linear combination of the EOFs. This method is applied to temperature data collected at a two vertical moorings in the 2006 New Jersey Shelf Shallow Water Experiment (SW06). Resulting profiles specify conditions for 35 days from sea surface to seafloor at a primary site and allow for reliable acoustic propagation modeling, mode decomposition, and beamforming.This work was supported by the U.S. Office of Naval Research (ONR) under Grants N00014-04-1-0146 and N00014-05-1- 0482, theONRPostdoctoral FellowshipAward under Grant N00014-08-1-0204, and by E. Livingston and T. Pawluskiewicz. The work of P. F. J. Lermusiaux and P. J. Haley was supported by the ONR under Grants N00014-07-1-1061, N00014-07-1-0501, and N00014-08-1-1097 to the Massachusetts Institute of Technology

The Impact of Assimilating Precipitation-affected Radiance on Cloud and Precipitation in Goddard WRF-EDAS Analyses

High-frequency TMI and AMSR-E radiances, which are sensitive to precipitation over land, are assimilated into the Goddard Weather Research and Forecasting Model- Ensemble Data Assimilation System (WRF-EDAS) for a few heavy rain events over the continental US. Independent observations from surface rainfall, satellite IR brightness temperatures, as well as ground-radar reflectivity profiles are used to evaluate the impact of assimilating rain-sensitive radiances on cloud and precipitation within WRF-EDAS. The evaluations go beyond comparisons of forecast skills and domain-mean statistics, and focus on studying the cloud and precipitation features in the jointed rainradiance and rain-cloud space, with particular attentions on vertical distributions of height-dependent cloud types and collective effect of cloud hydrometers. Such a methodology is very helpful to understand limitations and sources of errors in rainaffected radiance assimilations. It is found that the assimilation of rain-sensitive radiances can reduce the mismatch between model analyses and observations by reasonably enhancing/reducing convective intensity over areas where the observation indicates precipitation, and suppressing convection over areas where the model forecast indicates rain but the observation does not. It is also noted that instead of generating sufficient low-level warmrain clouds as in observations, the model analysis tends to produce many spurious upperlevel clouds containing small amount of ice water content. This discrepancy is associated with insufficient information in ice-water-sensitive radiances to address the vertical distribution of clouds with small amount of ice water content. Such a problem will likely be mitigated when multi-channel multi-frequency radiances/reflectivity are assimilated over land along with sufficiently accurate surface emissivity information to better constrain the vertical distribution of cloud hydrometers

Particle entrapment as a feedback effect

We consider a suspension of polarizable particles under the action of traveling wave dielectrophoresis (DEP) and focus on particle induced effects. In a situation where the particles are driven by the DEP force, but no external forces are exerted on the fluid, the joint motion of the particles can induce a steady fluid flow, which leads to particle entrapment. This feedback effect is proven to be non-negligible even for small volume concentration of particles.Comment: 4 pages, 4 figures, submitte

A three-dimensional underwater sound propagation model for offshore wind farm noise prediction.

Author Posting. © Acoustical Society of America, 2019. This article is posted here by permission of Acoustical Society of America for personal use, not for redistribution. The definitive version was published in Journal of the Acoustical Society of America 145(5), (2019):EL335-EL340, doi: 10.1121/1.5099560.A three-dimensional underwater sound propagation model with realistic ocean environmental conditions has been created for assessing the impacts of noise from offshore wind farm construction and operation. This model utilizes an existing accurate numerical solution scheme to solve the three-dimensional Helmholtz wave equation, and it is compared and validated with acoustic transmission data between 750 and 1250 Hz collected during the development of the Block Island Wind Farm (BIWF), Rhode Island. The variability of underwater sound propagation conditions has been investigated in the BIWF area on a temporal scale of months and a spatial scale of kilometers. This study suggests that future offshore wind farm developments can exploit the seasonal variability of underwater sound propagation for mitigating noise impact by scheduling wind farm construction during periods of high acoustic transmission loss. Discussions on other applications of soundscape prediction, planning, and management are provided.The authors would like to acknowledge Captain Ken Houlter and First Mate Ian Hanley of the WHOI R/V Tioga. The authors would also like to acknowledge Dr. Steven Crocker from the Naval Undersea Warfare Center in Newport, Rhode Island for the design of the tetrahedral hydrophone array. Study concept, oversight, and funding under the Real-time Opportunity for Development Environmental Operations (RODEO) were provided by the U.S. Department of the Interior, Bureau of Ocean Energy Management, Environmental Studies Program, Washington, DC under Contract No. M16PD00025. The Program Manager at BOEM is Dr. Mary Boatman. The prime contractor for this work is HDR, Inc. (Program Manager Anwar Khan).2019-11-0

The effects of pentoxifylline on lipopolysaccharide (LPS) fever, plasma interleukin 6 (IL 6), and tumor necrosis factor (TNF) in the rat

The purpose of these studies was to test whether pentoxifylline, a drug that can inhibit the production and action of cytokines hypothesized to be endogenous pyrogens (for example, interleukin 1 and tumor necrosis factor [TNF]), is antipyretic. We also tested the effects of pentoxifylline on plasma activities of interleukin 6 (IL 6) and TNF in response to an injection of a fever-inducing dose of lipopolysaccharide (LPS). Our results showed that a high dose of pentoxifylline (200 mg/kg) caused hypothermia in control rats and blocked LPS fever, while a low dose (50 mg/kg) did not have these effects. Injection of the high dose of pentoxifylline in control rats caused a rise in plasma IL 6 but not in plasma TNF. However, the peak levels of plasma IL 6 and TNF activities following an injection of LPS were significantly reduced by pretreatment with pentoxifylline. Overall, the data are consistent with the hypothesis that pentoxifylline is an antipyretic drug, which may act at least in part by inhibiting the secretion of pyrogenic cytokines.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/28504/1/0000301.pd

The effects of psychological stress on plasma interleukin-6 activity in rats

The purpose of this study was to determine the effects of a particular psychological stress, exposure to an open-field, on plasma IL-6 activity in rats. Plasma IL-6 activity was 40.6+/-7.2 units/ml in control rats, 105+/-6.8 units/ml after 30 minutes exposure to an open-field, and 221+/-17 units/ml after 60 minutes of exposure (p=0.0003). There was a positive correlation (r=.71, p=0.043) between the change in plasma IL-6 activity and body temperature. However, we conclude, based on earlier data relating plasma IL-6 activity to body temperature changes following injection of lipopolysaccharide, that the plasma levels of IL-6 following exposure to an open-field are not high enough to account for the rise in body temperature observed in rats during this stress. In conclusion, these experiments indicate that exposure to psychological stress can elevate the plasma concentration of IL-6, a known mediator of the acute phase response.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/28610/1/0000422.pd

Influenza Virus Infection in Travelers to Tropical and Subtropical Countries

Background. Influenza outbreaks have been reported among travelers, but attack rates and incidence are unknown. Methods. A cohort study was conducted. Travelers to subtropical and tropical countries recruited at the University of Zurich Travel Clinic (Switzerland), January 1998 to March 2000, were investigated with pre- and posttravel assessment of hemagglutination inhibition and by questionnaire. Results. Among 1450 travelers recruited who completed questionnaires and provided serum samples before departure, 289 (19.9%) reported febrile illness during or after traveling abroad; of these, 211 (73.0%) provided paired serum samples. Additionally, paired serum samples were collected from 321 frequency-matched afebrile control subjects among the remaining 1161 subjects of the study population. Seroconversion for influenza virus infection was demonstrated in 40 (2.8%) of all travelers; 18 participants (1.2%) had a ⩾4-fold increase in antibody titers. This corresponds to an incidence of 1.0 influenza-associated events per 100 person-months abroad. Among the 211 febrile participants, 27 (12.8%) had seroconversion, 13 (6.2%) with a ⩾4-fold increase; among the 321 afebrile control subjects, 13 (4.0%) had seroconversion, 5 (1.6%) with a ⩾4-fold increase. Twenty-five seroconverters (62.5%; P = .747) acquired influenza outside of the European epidemic season. Sixteen patients (40.0%) sought medical attention either abroad or at home, and 32 (80.0%) were asymptomatic at the time of completion of the survey. Conclusions. This survey indicates that influenza is the most frequent vaccine-preventable infection among travelers to subtropical and tropical countries. Infections occur mainly outside the domestic epidemic season, and they have a considerable impact. Pretravel vaccination should be considered for travelers to subtropical and tropical countrie