Effects of Recreational Activity on Leisure Barriers between Students

Recreation, which means relaxing and pleasant activities that people do voluntarily in their free time, is a concept that provides the physical and psychological renewal of individuals. The study was conducted on a total of 497 students, 248 men participating in recreational sports activities and 249 men who did not participate in any recreational activities. For this purpose “Leisure Constraints Scale”, which was developed by Alexandris and Carroll (1997) and was conducted in the study of the validity and reliability for Turkish Society by Karaküçük and Gürbüz (2007) was used. Statistical analysis of the study was performed by using SPSS 22,0 package program. The normality hypothesis of the data was analyzed by Kolmogorov-Smirnov test. Since all variables showed normal distribution, parametric tests were applied to the independent variables related to the sub-problems and the leisure time scale subscales. Independent t test was used for paired comparisons and Pearson correlation was used for the relationship between variables. Statistical results were evaluated at 95% confidence interval and p <0.05 significance level. As a result, statistically significant differences were found between the students participating in sportive recreation activity in the field and those who did not participate in any recreational activity in terms of leisure time barriers in terms of Individual Psychology, Social Environment, Service and Transportation, Time, Lack of Friends and Lack of Interest. (p<0, 05)

Evaluation of The Number of Rainy Days Observed for Long Years Due to Global Climate Change in Nevşehir /Turkey

In this research caried out Nevsehir province, Avanos and Ürgüp districts of Turkey's Central Anatolia Nevsehir. In the study, it is aimed to reveal the trends of years by changing the number of long year total rainy days by Mann Kendall and Sperman's Rho correlation tests. Within the scope of the study, 34 years long total monthly rainy days data between 1986-2019, which were obtained from automatic meteorology stations, were evaluated. According to the results of the trend analysis, the average total number of rainy days in Nevşehir province was 77 days minimum, the maximum number of rainy days was 142 days, and the average of the average number of rainy days was 109 days. In Avanos district, the average number of rainy days for a long time was 57 days, and the maximum number of rainy days was 129 days, while the average of the number of rainy days for long years was 89 days. In Ürgüp district, the average number of rainy days for a long time was 65 days, the maximum number of rainy days was 129 days, and the average of the number of rainy days for long years was 95 days. As a result, considering the number of long year rainy days, it is concluded that there is no significant trend in Nevşehir province, Avanos and Ürgüp district stations

IN VITRO EFFECTS OF NEW GENERATION BISOXADIAZOLE SUBSTITUTED SULFONAMIDE DERIVATIVES ON HUMAN SERUM PARAOXONASE1 (PON1)

In this study, new bisoxadiazole substituted sulfonamide compounds were synthesized and in vitro inhibition effects of the compouds on purified human serum paraoxonase 1 (PON I) were investigated by using the method of Gan et al. The results showed that all the synthesized compounds inhibited the paraoxonase 1 enzyme activity. The compounds 6d and 6e were found to be most active compounds (IC50=26.5 mu M and 28.6 mu M) for PON1, respectively

Comparison between rest technetium-99m-tetrofosmin and rest-redistribution thallium-201 SPECT in stable patients with healed myocardial infarction

Resting Tc-99m-tetrofosmin (TF) uptake was compared with thallium (Tl-201) rest-redistribution (R-RD) uptake in patients with previous myocardial infarction (MI) and significant coronary artery disease (CAD) to assess the ability of TF to detect viable myocardium. We studied 30 patients (21 males and nine females, mean age 53.9 +/- 12.5 years) with prior MI and left ventricular dysfunction who had been referred for coronary revascularization procedures. Myocardial single photon emission computed tomography (SPECT) images were obtained 1 h after injection of 750 MBq of TF. Within I week of the TT study, R-RD Tl-201 SPECT imaging was performed after injection of 111 MBq of Tl-201. Quantitative analysis was performed in 21 segments. Viability was defined as the presence of tracer uptake greater than 50% of the peak activity on baseline studies or after reversibility. There was significant correlation between the quantitative regional R-RD Tl-201 activity and the resting TF activity (r=0.88, P<0.001). Quantitative analysis showed that the uptake of the two tracers was comparable in normal segments as well as in segments with fixed Tl-201 defects. In contrast, in segments with reversible Tl-201 defects, TF uptake was significantly greater than resting Tl-201 uptake, but lower than R-RD Tl-201 uptake. There were 52 segments (47% of the severely reduced segments on TF images) that showed no viability with TF, but were viable on the redistribution Tl-201 studies. We conclude that quantitative resting TF SPECT underestimates the presence of viable myocardium compared with R-RD Tl-201 imaging on the basis of using 50% of the peak activity as the viability threshold. ((C) 2001 Lippincott Williams & Wilkins)

Combination of First Generation Proteasome Inhibitor Bortezomib with Temozolomide and Radiotherapy in Glioblastoma 2D and 3D Cell Cultures

Glioblastoma is the most common high-grade brain tumor in adults, which has a rapidly developing radiotherapy/chemotherapy resistance and high recurrence rate. The aim of our study is to determine the effects of bortezomib that is a quite important proteasome inhibitor on glioblastoma tumors in the 3D environment. In this study, we have performed bortezomib and temozolomide drug treatments and radiation applications to U251 cell line in 2D and 3D cultures with PCL/gelatin/graphene nanofibrous scaffolds. The best result was reached in the combination of drugs with radiation therapy that has the most decreased viability in the experiment group

Possible death mechanisms other than respiratory asphyxia in a suicidal hanging case

Hanging is the most common suicide method that has seen in the routine autopsy practice. Known mechanisms of death include asphyxiation due to airway obstruction, cerebral ischemia due to arterial blockage, vagal inhibition (reflex cardiac arrest) due to carotid sinus compression, congestion due to venous blockage, fractures in cervical vertebral column with the cord injury

Evaluation of the Relationship of Blood Heavy Metal, Trace Element Levels and Antioxidative Metabolism in Cattle Which Are Living Near The Trunk Roads

In this study, detection of a possible relationship of some trace element levels of copper (Cu), zinc (Zn), and iron (Fe), toxic heavy metals, cadmium (Cd) and lead (Pb), and antioxidant functions in cattle, which are living near the trunk roads for at least 3 years, was aimed. Totally, 70 cattle, which were in different herds, were used. Fifty-four cattle (3-13 years), which were living near the trunk roads at about 0-500 m were used for the experiment group. Also, 16 cattle (3-12 years), which were living far from trunk roads at about 2-3 km were used for the control groups. Blood samples were collected and Cd, Pb, Cu, Zn, Fe levels, lipid peroxidation product malondialdehyde (MDA) and antioxidative defense system indicators, erythrocyte superoxide dismutase (SOD) activity, catalase (CAT) activity, and plasma ceruloplasmin (CP) level were measured. Cd and Pb levels of the experimental animals were determined to be higher than the control group (P<0.01 and P<0.001, respectively). However, Zn level of the experiment group was found lower than the control animals (P<0.001). MDA increased about three times and CP increased about two times more than the control group (P<0.001). Significantly correlations were observed among Pb, MDA and CP levels. Also, important correlations were found between Fe and CP, also Cu and MDA levels. Besides, MDA and CAT levels of the animals increased with CP and SOD together, respectively. At the end of the study, Cd and Pb accumulation was observed in cattle, which were living near the road with intensive traffic for at least three years when compared with the control group. In addition, the results showed significant interactions among toxic heavy metals, physiological trace elements, enzymatic and non-enzymatic antioxidants and the lipid peroxidation