Simplified numerical models to simulate hollow monopile wind turbine foundations

The majority of wind turbine foundations consist of hollow monopiles inserted in the soil, requiring high computational effort to be numerically simulated. Alternative simplified models are very often employed instead. Three-dimensional solid models, in which the hollow structure and pile are substituted by solid cylinders with equivalent properties, are the most extended simplifications. Very few 2D models can be found in the literature due to the challenge of finding suitable equivalent properties and loads to fully represent the 3D nature of the problem. So far, very limited attention has been devoted to the accuracy of both 3D and 2D simplified models under dynamic and even static actions. Thus, in this paper, simplified 3D and 2D solid models are proposed and justified. An elasto-plastic constitutive model with accumulative degradation is used to simulate the soil behaviour, and frictional contact elements are implemented between the soil and pile to model their interaction. These simplified approaches are compared with the full 3D hollow model, under static and cyclic loads. The results demonstrate that the proposed simplified approaches are a reasonable alternative to the 3D hollow model, which allows researchers and designers to drastically reduce the computational effort in the simulations under long term conditions

Cooperative learning as a methodology to learn mechanical properties of materials in Civil Engineering

[EN] The current work presents an activity developed by first-year undergraduate students of Civil Engineering at the University of Castilla-La Mancha. Due to the character of this activity and the type of organisation of the students in small groups (3 people in each group), this activity can be defined as Cooperative Learning (CL). In this process, students must estimate by using an experimental design the Young’s Modulus of a rubber elastic band, which has been previously delivered to the students by the professor. Before the beginning of this task, students have studied all the necessary theoretical concepts to develop this experiment, however neither kind of extra indications have been given to them about how to resolve it, so that they should elucidate on their own a testing methodology which allow them to reach the goal of this task. This activity has been carried out for five years, and in spite of its non mandatory character, students have showed a great interest and motivation for it. Paying attention to several criteria such as evaluation, reached objectives or the involvement of the students. The results obtained from the activity have been highly satisfactory both for professors and students.The content of this document is structured as follow: first, the educational context is exposed including the development the subject and the most singular characteristics of the degree. After that, both the curriculum of the subject and the traditional way of teaching Elasticity are exposed. Moreover, it is described the learning strategy proposal and some of the solutions adopted by students. Finally, the most relevant conclusions are drawn.[ES] En el presente artículo se muestra una actividad propuesta a los alumnos de primer curso de Ingeniería Civil en la Escuela de Ingenieros de Caminos, Canales y Puertos de la Universidad de Castilla-La Mancha. Por la orientación del trabajo y la distribución en pequeños grupos (3 alumnos por grupo) se trata de una actividad clasificada dentro de la tipología de Aprendizaje Cooperativo (AC). Dicha actividad consiste en calcular de forma experimental el módulo de elasticidad de una banda elástica de goma, previamente entregada por el profesor.Los alumnos poseen los conocimientos teóricos necesarios para afrontar dicho experimento, pero no se les ha dado ninguna indicación previa de cómo llevarlo a cabo, así pues deberán dilucidar una metodología de ensayo propia que les lleve hasta la solución del problema. La actividad propuesta, se ha desarrollado durante seis cursos académicos y aunque de carácter voluntario, tiene una gran acogida por parte del alumnado. Los resultados obtenidos atendiendo a criterios como: evaluación, consecución de objetivos, implicación del alumnado, etc. han sido muy satisfactorios.En este documento, en primer lugar se realiza una presentación del contexto educativo en el que queda inmersa la asignatura y algunas de las características más singulares de la titulación. A continuación se presenta el curriculum de la asignatura y se describe la metodología clásica de enseñanza del concepto de elasticidad para, posteriormente, describir la estrategia docente propuesta. Finalmente se muestran algunas de las soluciones adoptadas por los alumnos para realizar la actividad y se presentan las conclusiones más relevantes.Porras, R.; Arias-Trujillo, J. (2016). El aprendizaje cooperativo como metodología para estudiar las propiedades mecánicas de los materiales en la Ingeniería Civil. REDU. Revista de Docencia Universitaria. 14(2):37-55. doi:10.4995/redu.2016.5677.SWORD375514

Effect of polymer emulsion of the bearing capacity of Aeolian sand under extreme confinement conditions

An experimental investigation, aimed at evaluating the improvement of Aeolian sand (from Saudi Arabia) when treated with low dosages of a vinyl acrylic (a polymer emulsion), is reported in this paper. Special attention is devoted to the influence of the lateral confinement, particularly in terms of compaction and bearing capacity (represented by CBR), for which a modification of the standard test has been developed trying to simulate extreme confinement conditions. Experimental results demonstrate that this kind of chemical stabilizers can be considered as a suitable alternative for these materials. The main modifications induced in the sand by this additive are highlighted and quantified by means of the modification achieved for different geotechnical properties as well as Scanning Electron Microscope (SEM) and Energy-Dispersive X-Ray Spectroscopy (EDX) analyses

A numerical approach for liquefaction potential definition

Liquefaction phenomenon in saturated granular soil is not that frequent as amplification cases but can cause heavy damages on buildings and infrastructures whenever is occurs especially within superficial strata. In fact the lack of shear resistance of soil due to liquefaction affects mostly shallow foundations and road surfaces. Up now, several studies have been addressed to overpass the inadequacy of liquefaction safety factor by means of introducing the liquefaction potential. Nevertheless, the difficulty in (1) defining a scale of damage related to liquefaction potential values and (2) collecting field data from damages caused prevalently by liquefaction makes the punctual factor of safety still popular in engineering practice. In this paper a new approach to liquefaction potential estimation is proposed based on finite element dynamic analyses and on the concept of “significant volume” according to possible effects suffered by shallow foundations. One-dimensional simulation of liquefaction occurrence is performed by means of the Pastor-Zienkiewicz constitutive law. Hence the estimation of liquefaction potential is gained as well as the stress influence factor from Westergaard solution is calculated

Simplified Numerical Models to Simulate Hollow Monopile Wind Turbine Foundations

© 2020 by the authors. The majority of wind turbine foundations consist of hollow monopiles inserted in the soil, requiring high computational effort to be numerically simulated. Alternative simplified models are very often employed instead. Three-dimensional solid models, in which the hollow structure and pile are substituted by solid cylinders with equivalent properties, are the most extended simplifications. Very few 2D models can be found in the literature due to the challenge of finding suitable equivalent properties and loads to fully represent the 3D nature of the problem. So far, very limited attention has been devoted to the accuracy of both 3D and 2D simplified models under dynamic and even static actions. Thus, in this paper, simplified 3D and 2D solid models are proposed and justified. An elasto-plastic constitutive model with accumulative degradation is used to simulate the soil behaviour, and frictional contact elements are implemented between the soil and pile to model their interaction. These simplified approaches are compared with the full 3D hollow model, under static and cyclic loads. The results demonstrate that the proposed simplified approaches are a reasonable alternative to the 3D hollow model, which allows researchers and designers to drastically reduce the computational effort in the simulations under long term conditions

Improvement of the bearing capacity of confined and unconfined cement-stabilized aeolian sand

The improvement reached on the compaction and bearing capacity of aeolian sand collected in Jeddah (Saudi Arabia) after its stabilization with Portland cement is evaluated, comparing the behavior for both treated and untreated samples. With the aim of using this type of soil in the construction of embankments for road or railway applications, the results obtained have been evaluated in terms of maximum dry density, optimum moisture content (compaction test) and bearing capacity (CBR). Special attention has been paid to the influence of the confining conditions on the results, scarcely analyzed in the literature, by comparing the load-displacement curves during penetration stage in the CBR tests for both confined and unconfined specimens. Different contents of Portland cement have been explored (out of 6% of dry soil weight) to stabilize this material. The results obtained show a clear linear correlation between of compaction characteristics and CBR respect to the percentage of cement, obtaining, as expected, higher improvement for treated-material with higher content of cement, also strongly influenced by the confinement state. Thanks to this treatment, it is possible to employ this material in applications with low-confinement support, which is impossible without a previous proper stabilization. Finally, two practical indices have been defined to measure the degree of improvement reached, involving both cement content and confinement

4-1BBL as a Mediator of Cross-Talk between Innate, Adaptive, and Regulatory Immunity against Cancer

The ability of tumor cells to evade the immune system is one of the main challenges we confront in the fight against cancer. Multiple strategies have been developed to counteract this situation, including the use of immunostimulant molecules that play a key role in the anti-tumor immune response. Such a response needs to be tumor-specific to cause as little damage as possible to healthy cells and also to track and eliminate disseminated tumor cells. Therefore, the combination of immunostimulant molecules and tumor-associated antigens has been implemented as an antitumor therapy strategy to eliminate the main obstacles confronted in conventional therapies. The immunostimulant 4-1BBL belongs to the tumor necrosis factor (TNF) family and it has been widely reported as the most effective member for activating lymphocytes. Hence, we will review the molecular, pre-clinical, and clinical applications in conjunction with tumor-associated antigens in antitumor immunotherapy, as well as the main molecular pathways involved in this association

Hawksbill turtle terra incognita: conservation genetics of eastern Pacific rookeries

Prior to 2008 and the discovery of several important hawksbill turtle (Eretmochelys imbricata) nesting colonies in the EP (Eastern Pacific), the species was considered virtually absent from the region. Research since that time has yielded new insights into EP hawksbills, salient among them being the use of mangrove estuaries for nesting. These recent revelations have raised interest in the genetic characterization of hawksbills in the EP, studies of which have remained lacking to date. Between 2008 and 2014, we collected tissue samples from 269 nesting hawksbills at nine rookeries across the EP and used mitochondrial DNA sequences (766 bp) to generate the first genetic characterization of rookeries in the region. Our results inform genetic diversity, population differentiation, and phylogeography of the species. Hawksbills in the EP demonstrate low genetic diversity: We identified a total of only seven haplotypes across the region, including five new and two previously identified nesting haplotypes (pooled frequencies of 58.4% and 41.6%, respectively), the former only evident in Central American rookeries. Despite low genetic diversity, we found strong stock structure between the four principal rookeries, suggesting the existence of multiple populations and warranting their recognition as distinct management units. Furthermore, haplotypes EiIP106 and EiIP108 are unique to hawksbills that nest in mangrove estuaries, a behavior found only in hawksbills along Pacific Central America. The detected genetic differentiation supports the existence of a novel mangrove estuary “reproductive ecotype” that may warrant additional conservation attention. From a phylogeographic perspective, our research indicates hawksbills colonized the EP via the Indo‐Pacific, and do not represent relict populations isolated from the Atlantic by the rising of the Panama Isthmus. Low overall genetic diversity in the EP is likely the combined result of few rookeries, extremely small reproductive populations and evolutionarily recent colonization events. Additional research with larger sample sizes and variable markers will help further genetic understanding of hawksbill turtles in the EP

Why Are Outcomes Different for Registry Patients Enrolled Prospectively and Retrospectively? Insights from the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF).

Background: Retrospective and prospective observational studies are designed to reflect real-world evidence on clinical practice, but can yield conflicting results. The GARFIELD-AF Registry includes both methods of enrolment and allows analysis of differences in patient characteristics and outcomes that may result. Methods and Results: Patients with atrial fibrillation (AF) and ≥1 risk factor for stroke at diagnosis of AF were recruited either retrospectively (n = 5069) or prospectively (n = 5501) from 19 countries and then followed prospectively. The retrospectively enrolled cohort comprised patients with established AF (for a least 6, and up to 24 months before enrolment), who were identified retrospectively (and baseline and partial follow-up data were collected from the emedical records) and then followed prospectively between 0-18 months (such that the total time of follow-up was 24 months; data collection Dec-2009 and Oct-2010). In the prospectively enrolled cohort, patients with newly diagnosed AF (≤6 weeks after diagnosis) were recruited between Mar-2010 and Oct-2011 and were followed for 24 months after enrolment. Differences between the cohorts were observed in clinical characteristics, including type of AF, stroke prevention strategies, and event rates. More patients in the retrospectively identified cohort received vitamin K antagonists (62.1% vs. 53.2%) and fewer received non-vitamin K oral anticoagulants (1.8% vs . 4.2%). All-cause mortality rates per 100 person-years during the prospective follow-up (starting the first study visit up to 1 year) were significantly lower in the retrospective than prospectively identified cohort (3.04 [95% CI 2.51 to 3.67] vs . 4.05 [95% CI 3.53 to 4.63]; p = 0.016). Conclusions: Interpretations of data from registries that aim to evaluate the characteristics and outcomes of patients with AF must take account of differences in registry design and the impact of recall bias and survivorship bias that is incurred with retrospective enrolment. Clinical Trial Registration: - URL: http://www.clinicaltrials.gov . Unique identifier for GARFIELD-AF (NCT01090362)