23 research outputs found

    Providing Personalized Guidance in Arithmetic Problem Solving

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    Supervising a student's resolution of an arithmetic word problem is a cumbersome task. Di erent students may use di erent lines of reasoning to reach the nal solution, and the assistance provided should be consistent with the resolution path that the student has in mind. In addition, further learning gains can be achieved if the previous student's background is also considered in the process. In this paper, we outline a relatively simple method to adapt the hints given by an Intelligent Tutoring System to the line of reasoning that the student is currently following. We also outline possible extensions to build a model of the student's most relevant skills, by tracking user's actions

    Functional proteomics outlines the complexity of breast cancer molecular subtypes

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    Breast cancer is a heterogeneous disease comprising a variety of entities with various genetic backgrounds. Estrogen receptor-positive, human epidermal growth factor receptor 2-negative tumors typically have a favorable outcome; however, some patients eventually relapse, which suggests some heterogeneity within this category. In the present study, we used proteomics and miRNA profiling techniques to characterize a set of 102 either estrogen receptor-positive (ER+)/progesterone receptorpositive (PR+) or triple-negative formalin-fixed, paraffin-embedded breast tumors. Protein expressionbased probabilistic graphical models and flux balance analyses revealed that some ER+/PR+ samples had a protein expression profile similar to that of triple-negative samples and had a clinical outcome similar to those with triple-negative disease. This probabilistic graphical model-based classification had prognostic value in patients with luminal A breast cancer. This prognostic information was independent of that provided by standard genomic tests for breast cancer, such as MammaPrint, OncoType Dx and the 8-gene Score

    Banbuaren karakterizazio mekanikoa eta kimikoa

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    The bamboo, a tubular geometry plant, it is a promising replacement of traditional synthetic materials in the construction sector. In addition, it is renewable and environmentally sustainable. However, in order to promote its use, mechanical and chemical properties of bamboo must be known. This work analyses chemical and mechanical characteristics of three bamboo species not used in the construction sector, but widely used for other purposes: Phyllostachys aurea (PA), Arundinaria amabilis (AA) and Dendrocalamus strictus (DS). TAPPI standards have been used for the chemical analysis, while mechanical properties have been studied in compression and three-point flexion tests. The results have shown that the density of bamboo has a direct influence on mechanical properties, both in resistance and stiffness: for the analysed three bamboo species, the higher density the higher resistance and stiffness.; Banbuak, geometria tubularreko landareak, material sintetiko tradizionalen ordezko aukera interesgarriak aurkezten ditu eraikuntzaren sektorerako. Gainera, ingurumenaren aldetik jasangarria eta berriztagarria da. Hala ere, bere erabilera sustatzeko, beharrezkoa da banbuen propietate mekanikoak eta kimikoak ezagutzea. Lan honek gaur egun eraikuntzan ezezagunak diren baina tradizionalki oso erabiliak izan diren hiru espezie aztertzen ditu, kimikoki eta mekanikoki: dendrocalamus strictus (DS), Arundinaria amabilis (AA) eta Phyllostachys aurea (PA). Azterketa kimikorako, TAPPI arauak erabili dira, eta ezaugarri mekanikoak konpresioan eta dinamometroarekin makurdura hiru puntutan neurtuta aztertu dira. Propietate mekanikoen emaitzek erakutsi dute banbuaren dentsitateak eragin zuzena duela bai erresistentzian, bai zurruntasunean. Aztertutako hiru banbu-espezieetan, dentsitatea zenbat eta handiagoa izan, erresistentzia eta zurruntasuna orduan eta handiagoak direla ikusi da

    Banbuaren karakterizazio mekanikoa eta kimikoa

    Get PDF
    The bamboo, a tubular geometry plant, it is a promising replacement for traditional synthetic materials in the construction sector. In addition, it is renewable and environmentally sustainable. However, in order to promote its use, mechanical and chemical properties of bamboo must be known. This work analyses chemical and mechanical characteristics of three bamboo species not used in the construction sector, but widely used for other purposes: Dendrocalamus strictus (DS), Arundinaria amabilis (AA) and Phyllostachys aurea (PA). TAPPI standards have been used for the chemical analysis, while mechanical properties have been studied in compression and three-point flexion tests. The results have shown that the density of bamboo has a direct influence on mechanical properties, both in resistance and stiffness: for the analysed three bam-boo species, the higher density the higher resistance and stiffness.; Banbua, geometria tubularra duen landarea den aldetik, hautagai interesgarria da eraikuntzaren sektorerako material sintetiko tradizionalen ordezko gisa erabiltzeko. Gainera, iraunkorra eta berriztagarria da ingurumenarekiko arretari dagokionez. Hala ere, haren erabilera sustatzeko, beharrezkoa da dituen propietate mekanikoak eta kimikoak ezagutzea. Lan honek kimikaren eta mekanikaren ikuspegitik aztertzen ditu gaur egun eraikuntzan ezezagunak diren baina tradizionalki oso erabiliak izan diren hiru banbu-espezie: Dendrocalamus strictus (DS), Arundinaria amabilis (AA) eta Phyllostachys aurea (PA). Azterketa kimikorako TAPPI arauak erabili dira, eta ezaugarri mekanikoak konpresioan eta dinamometroa baliatuz makurdura hiru puntutan neurtuta aztertu dira. Propietate mekanikoen emaitzek erakutsi dute banbuaren dentsitateak eragin zuzena duela bai erresistentzian eta bai zurruntasunean. Aztertutako hiru banbu espezieetan, dentsitatea zenbat eta handiagoa izan, erresistentzia eta zurruntasuna handiagoak direla ikusi da

    Optogenetic control of gene expression in plants in the presence of ambient white light

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    Optogenetics is the genetic approach for controlling cellular processes with light. It provides spatiotemporal, quantitative and reversible control over biological signaling and metabolic processes, overcoming limitations of chemically inducible systems. However, optogenetics lags in plant research because ambient light required for growth leads to undesired system activation. We solved this issue by developing plant usable light-switch elements (PULSE), an optogenetic tool for reversibly controlling gene expression in plants under ambient light. PULSE combines a blue-light-regulated repressor with a red-light-inducible switch. Gene expression is only activated under red light and remains inactive under white light or in darkness. Supported by a quantitative mathematical model, we characterized PULSE in protoplasts and achieved high induction rates, and we combined it with CRISPR–Cas9-based technologies to target synthetic signaling and developmental pathways. We applied PULSE to control immune responses in plant leaves and generated Arabidopsis transgenic plants. PULSE opens broad experimental avenues in plant research and biotechnology

    Cognitive Reasoning and Inferences through Psychologically based Personalised Modelling of Emotions Using Associative Classifiers

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    Presentation available from: http://www.slideshare.net/AladdinAyesh/v1-cognitive-informaticspresentation201

    Estrategias de aprendizaje activo basado en trabajos de curso

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    Los trabajos de curso y boletines de ejercicios de entrega periódica son un elemento útil para desarrollar competencias y promover el aprendizaje fuera del aula. Sin embargo, generalmente esta técnica requiere la corrección de una gran cantidad de trabajos para proporcionar una realimentación adecuada y constante al alumno, una actividad que consume una parte importante del tiempo del profesor. En este artículo presentamos una estrategia que permite proporcionar niveles de realimentación adecuados reduciendo el tiempo de dedicación del docente, al tiempo que sirve como guía para el desarrollo de contenidos y para la consecución de objetivos de la asignatura. Esta propuesta, junto con otras actividades transversales, se ha puesto en marcha en diversas asignaturas. En este artículo presentamos los resultados obtenidos en un caso particular, siendo éstos representativos del resto.SUMMARY -- Course Works and exercise bulletins are useful to develop transferrable skills and foster learning outside the classroom. However, these usually imply dedicating a large amount of resources for marking and providing adequate feedback to the student. In this article, we present a strategy that allows the lecturer to provide adequate feedback with a lesser effort. In addition, the method can be used as an aid to content development and to achieve the learning objectives of the module. This proposal, together with other activities, has been employed in several modules. In this article, results for a particular case which is representative for all other cases are presented.Peer Reviewe
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