Renormalization of Poincare Transformations in Hamiltonian Semiclassical Field Theory

Semiclassical Hamiltonian field theory is investigated from the axiomatic point of view. A notion of a semiclassical state is introduced. An "elementary" semiclassical state is specified by a set of classical field configuration and quantum state in this external field. "Composed" semiclassical states viewed as formal superpositions of "elementary" states are nontrivial only if the Maslov isotropic condition is satisfied; the inner product of "composed" semiclassical states is degenerate. The mathematical proof of Poincare invariance of semiclassical field theory is obtained for "elementary" and "composed" semiclassical states. The notion of semiclassical field is introduced; its Poincare invariance is also mathematically proved.Comment: LaTeX, 40 pages; short version of hep-th/010307

BIOINFORMATION SEARCH AND ANALYSIS OF STRUCTURES OF CRISPR/CAS SYSTEMS IN PHAGE STAPHYLOCOCUS AUREUS GENOME AND ESTIMATION OF PROFILES OF PHAGE DETECTED THROUGH CRISPR-CASSETTE BACTERIA

The emergence of resistance among the most important bacterial pathogens is generally recognized as one of the major public health problems. The most important of these organisms are penicillin-resistant Streptococcus pneumoniae, vancomycin-resistant enterococci and methicillin- and vancomycin-resistant Staphylococcus aureus. These antibiotic resistance in common pathogens have made antimicrobial therapy of many infections. Scientists need to look for new ways of treating bacterial infections in the work, using the developed algorithm from the methods of search software in the genomic structure of Staphylococcus aureus subsp. aureus ST228, the CRISPR/Cas locus and the division structures of its CRISPR cassette. The results of the bacteriophage search through the decoded spacer sequences of CRISPR-cassettes of this strain were also obtained using the developed algorithm of the software methods of bioinformatics. It was determined that the CRISPR/Cas system of strain of ST228 of S. aureus was of type IIIA. It is shown that cas-genes are in the immediate vicinity of CRISPR cassettes. The spacer structures in the detected CRISPR cassette are the Staphylococcus, Mycobacterium, Streptococcus, Bacillus, Gordonia, Arthrobacter, Streptomyces. The implementation of the algorithm of program methods for locating CRISPR/Cas-loci can be applied to many other decoded bacterial genomes to return bacteriophage therapy

Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis

Supported by F. Hoffmann–La Roche

THE USE OF BIOLOGICAL PRODUCTS IN ABDOMINAL SURGERY AND LIVER TRANSPLANTATION

This article provides an overview of new approaches to the prevention of infectious complications of bacterial nature after the high-technology operations in the abdominal surgery, first of all, after liver transplantation. At- tention is drawn to the first positive results of randomized studies on the use of biological preparations - probi- otics, prebiotics and synbiotics in patients after liver transplantation. The authors prove the prospects of further development of this subject based on successful model experiments on animals and various operational interven- tions in abdominal surgery

ИСПОЛЬЗОВАНИЕ БИОПРЕПАРАТОВ В АБДОМИНАЛЬНОЙ ХИРУРГИИ И ТРАНСПЛАНТАЦИИ ПЕЧЕНИ

This article provides an overview of new approaches to the prevention of infectious complications of bacterial nature after the high-technology operations in the abdominal surgery, first of all, after liver transplantation. At- tention is drawn to the first positive results of randomized studies on the use of biological preparations - probi- otics, prebiotics and synbiotics in patients after liver transplantation. The authors prove the prospects of further development of this subject based on successful model experiments on animals and various operational interven- tions in abdominal surgery. В статье представлен обзор новых подходов к профилактике инфекционных осложнений бактериаль- ной природы после проведения высокотехнологичных операций в абдоминальной хирургии, прежде всего, трансплантации печени. Обращается внимание на первые положительные результаты рандоми- зированных исследований по использованию биологических препаратов – пробиотиков, пребиотиков и симбиотиков у пациентов после трансплантации печени. Обосновывается перспективность дальнейшей разработки этого вопроса успешными модельными экспериментами на животных и различными опера- тивными вмешательствами в абдоминальной хирургии.