5,009 research outputs found

    Applying Abstract Argumentation Theory to Cooperative Game Theory

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    We apply ideas from abstract argumentation theory to study cooperative game theory. Building on Dung's results in his seminal paper, we further the correspondence between Dung's four argumentation semantics and solution concepts in cooperative game theory by showing that complete extensions (the grounded extension) correspond to Roth's subsolutions (respectively, the supercore). We then investigate the relationship between well-founded argumentation frameworks and convex games, where in each case the semantics (respectively, solution concepts) coincide; we prove that three-player convex games do not in general have well-founded argumentation frameworks.Comment: 15 pages, 1 tabl

    Validity of self-reported smoking status: comparison of patients admitted to hospital with acute coronary syndrome and the general population

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    Many studies rely on self-reported smoking status. We hypothesized that patients with acute coronary syndrome (ACS), a smoking-related condition, would be more prone to misclassify themselves as ex-smokers, because of pressure to quit. We compared patients admitted with ACS with a general population survey conducted in the same country at a similar time. We determined whether ACS patients who classified themselves as ex-smokers (n = 635) were more likely to have cotinine levels suggestive of smoking deception than self-reported ex-smokers in the general population (n = 289). On univariate analysis, the percentage of smoking deceivers was similar among ACS patients and the general population (11% vs. 12%, p = .530). Following adjustment for age, sex and exposure to environmental tobacco smoke, ACS patients were significantly more likely to misclassify themselves (adjusted OR = 14.06, 95% CI 2.13-93.01, p = .006). There was an interaction with age whereby the probability of misclassification fell significantly with increasing age in the ACS group (adjusted OR = 0.95, 95% CI 0.93-0.97, p<.001), but not in the general population. Overall, smoking deception was more common among ACS patients than the general population. Studies comparing patients with cardiovascular disease and healthy individuals risk introducing bias if they rely solely on self-reported smoking status. Biochemical confirmation should be undertaken in such studies

    A Graph-Based Context-Aware Model to Understand Online Conversations

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    Online forums that allow for participatory engagement between users have been transformative for the public discussion of many important issues. However, such conversations can sometimes escalate into full-blown exchanges of hate and misinformation. Existing approaches in natural language processing (NLP), such as deep learning models for classification tasks, use as inputs only a single comment or a pair of comments depending upon whether the task concerns the inference of properties of the individual comments or the replies between pairs of comments, respectively. But in online conversations, comments and replies may be based on external context beyond the immediately relevant information that is input to the model. Therefore, being aware of the conversations' surrounding contexts should improve the model's performance for the inference task at hand. We propose GraphNLI, a novel graph-based deep learning architecture that uses graph walks to incorporate the wider context of a conversation in a principled manner. Specifically, a graph walk starts from a given comment and samples "nearby" comments in the same or parallel conversation threads, which results in additional embeddings that are aggregated together with the initial comment's embedding. We then use these enriched embeddings for downstream NLP prediction tasks that are important for online conversations. We evaluate GraphNLI on two such tasks - polarity prediction and misogynistic hate speech detection - and found that our model consistently outperforms all relevant baselines for both tasks. Specifically, GraphNLI with a biased root-seeking random walk performs with a macro-F1 score of 3 and 6 percentage points better than the best-performing BERT-based baselines for the polarity prediction and hate speech detection tasks, respectively.Comment: 25 pages, 9 figures. arXiv admin note: text overlap with arXiv:2202.0817

    Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1

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    TYW1 is a radical S-adenosyl-l-methionine (SAM) enzyme that catalyzes the condensation of pyruvate and N-methylguanosine to form the posttranscriptional modification, 4-demethylwyosine, in situ on transfer RNA (tRNA). Two mechanisms have been proposed for this transformation, with one of the possible mechanisms invoking a Schiff base intermediate formed between a conserved lysine residue and pyruvate. Utilizing a combination of mass spectrometry and X-ray crystallography, we have obtained evidence to support the formation of a Schiff base lysine adduct in TYW1. When 13 C labeled pyruvate is used, the mass shift of the adduct matches that of the labeled pyruvate, indicating that pyruvate is the source of the adduct. Furthermore, a crystal structure of TYW1 provides visualization of the Schiff base lysine-pyruvate adduct, which is positioned directly adjacent to the auxiliary [4Fe-4S] cluster. The adduct coordinates the unique iron of the auxiliary cluster through the lysine nitrogen and a carboxylate oxygen, reminiscent of how the radical SAM [4Fe-4S] cluster is coordinated by SAM. The structure provides insight into the binding site for tRNA and further suggests how radical SAM chemistry can be combined with Schiff base chemistry for RNA modification.National Science Foundation (U.S.) (Grant 1122374

    Who has the last word? Understanding How to Sample Online Discussions

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    In online debates individual arguments support or attack each other, leading to some subset of arguments being considered more relevant than others. However, in large discussions readers are often forced to sample a subset of the arguments being put forth. Since such sampling is rarely done in a principled manner, users may not read all the relevant arguments to get a full picture of the debate. This paper is interested in answering the question of how users should sample online conversations to selectively favour the currently justified or accepted positions in the debate. We apply techniques from argumentation theory and complex networks to build a model that predicts the probabilities of the normatively justified arguments given their location in online discussions. Our model shows that the proportion of replies that are supportive, the number of replies that comments receive, and the locations of un-replied comments all determine the probability that a comment is a justified argument. We show that when the degree distribution of the number of replies is homogeneous along the discussion, for acrimonious discussions, the distribution of justified arguments depends on the parity of the graph level. In supportive discussions the probability of having justified comments increases as one moves away from the root. For discussion trees that have a non-homogeneous in-degree distribution, for supportive discussions we observe the same behaviour as before, while for acrimonious discussions we cannot observe the same parity-based distribution. This is verified with data obtained from the online debating platform Kialo. By predicting the locations of the justified arguments in reply trees, we can suggest which arguments readers should sample to grasp the currently accepted opinions in such discussions. Our models have important implications for the design of future online debating platforms

    ‘Dominant ethnicity’ and the ‘ethnic-civic’ dichotomy in the work of A. D. Smith

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    This article considers the way in which the work of Anthony Smith has helped to structure debates surrounding the role of ethnicity in present-day nations. Two major lines of enquiry are evident here. First, the contemporary role of dominant ethnic groups within 'their' nations and second, the interplay between ethnic and civic elements in nationalist argument. The two processes are related, but maintain elements of distinctiveness. Smith's major contribution to the dominant ethnicity debate has been to disembed ethnicity from the ideologically-charged and/or anglo-centric discourse of ethnic relations and to place it in historical context, thereby opening up space for dominant group ethnicity to be considered as a distinct phenomenon. This said, Smith's work does not adequately account for the vicissitudes of dominant ethnicity in the contemporary West. Building on the classical works of Hans Kohn and Friedrich Meinecke, Anthony Smith has also made a seminal contribution to the debate on civic and ethnic forms of national identity and nationalist ideology. As well as freeing this debate from the strong normative overtones which it has often carried, he has continued to insist that the terms civic and ethnic should be treated as an ideal-typical distinction rather than a scheme of classification

    Vailulu’u Seamount

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    Author Posting. © Oceanography Society, 2010. This article is posted here by permission of Oceanography Society for personal use, not for redistribution. The definitive version was published in Oceanography 23, 1 (2010): 164-165.Vailulu’u seamount is an active underwater volcano that marks the end of the Samoan hotspot trail
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