Nasopharyngeal angiofibroma: review of literature

Angiofibroma of nasopharynx is a highly vascular, rare and benign tumor, with a high a incidence of recurrence and local invasity which nature always defied the researchers on the subject. The controversies start on its site of origin, till therapeutical modalities, passing by clinical and diagnostic aspects. The most serious and baffling feature, however, is the occurrence of hemorrhagic outbreaks, sometimes very intense, which may lead the patient to death. In view of this, the efforts developed towards of minimizing this problematic fact have been many, aiming adequate control of the illness. The present article presents a global review on this subject and intends to discuss the main aspects related to angiofibroma of nasopharynx in a simple and didatic form.O angiofibroma de nasofaringe é um tumor benigno, raro, altamente vascularizado, com elevado índice de recorrência e invasividade local, cuja natureza sempre desafiou os estudiosos do assunto. As controvérsias vão desde o seu local de origem, até modalidades terapêuticas, passando por aspectos clínicos e diagnósticos. A característica mais grave e desconcertante, no entanto, é a ocorrência de surtos hemorrágicos, por vezes muito intensos, podendo levar o paciente à morte. Frente a esse fato, muitos foram os esforços desenvolvidos no sentido de minimizar esse problema, visando o controle adequado da doença. Esse estudo apresenta uma revisão global sobre o tema e se propõe a expor de forma simples e didática os principais aspectos relacionados ao angiofibroma nasofaríngeo.Instituto de Assistência Médica ao Servidor Público Estadual de São PauloUNIFESP-EPMHSPE FMO Departamento de OtorrinolaringologiaHospital do Servidor Público Municipal Serviço de OtorrinolaringologiaUniversidade de São Paulo Faculdade de MedicinaHospital do Servidor Público Estadual FMO Departamento de OtorrinolaringologiaUNIFESP, EPMSciEL

Effect of adjuvant chemoradiotherapy on overall survival of gastric cancer patients submitted to D2 lymphadenectomy

Abstract Background Adjuvant chemoradiotherapy (CRT) is the standard treatment in Western countries for gastric cancer patients submitted to curative resection. However, the role of adjuvant CRT in gastric cancer treated with D2 lymphadenectomy has not been well defined. Conclusions In the present study, adjuvant CRT was associated with a lower risk of death over a 3-year period in gastric cancer patients treated with D2 lymphadenectomy

Paraganglioma carotídeo bilateral Bilateral carotid body paraganglioma

Os paragangliomas do corpo carotídeo são lesões incomuns, embora representem a maioria dos paragangliomas da cabeça e pescoço. A presença de lesão bilateral é rara. Os autores apresentam um caso de paraganglioma bilateral, dando ênfase aos aspectos clínicos, diagnósticos e tratamento.<br>Carotid body paragangliomas are uncommon lesions although in the head and neck region, these lesions are the most frequent ones. Bilateral lesions are rare. The authors present a case of bilateral paraganglioma, its clinical aspects, diagnosis and treatment

Histopathological analysis of corticosteroid-antibiotic preparation and propolis paste formulation as intracanal medication after pulpectomy: an in vivo study

Intracanal medication in pulpectomy therapy is used between appointments with the objective of reducing pain and inflammatory processes in pulp and periapical tissues. Propolis has been known as a natural antibiotic and has been subject of medical and dental research due to its therapeutic properties such as antibiotic, analgesic and anti-inflammatory effects. OBJECTIVE: The aim was to carry out an in vivo evaluation of the periapical tissue response to propolis paste when used as an intracanal medication in the teeth of dogs after pulpectomy. MATERIAL AND METHODS: 72 dog's incisors were selected for the experiment. After biomechanical preparation the root canal was filled with a corticosteroid-antibiotic preparation, experimental propolis paste, non-medicament (negative control) or non-pulpectomy at all (positive control). The medications were left inside the root canal for 7, 14 or 28 days. At the end of the experimental period histological sections were prepared and all laboratories processes for Harris hematoxylin and eosin staining was proceeded followed by the analysis using an optical microscope. Sections were classified according to a score representing the inflammatory events observed: the presence of polymorphonuclear neutrophils, polymorphonuclear eosinophils, lymphocytes and plasma cells, macrophages and/or giant cells, fibrous condensation and abscesses. RESULTS: There were statistically significant differences between the tissue reactions caused by the two substances being tested, after different experimental periods, with the periapical tissue that was in contact with propolis paste exhibiting fewer inflammatory reactions in comparison to corticosteroid-antibiotic preparation. CONCLUSIONS: The low tissue responses from propolis paste suggest that this material could be considered as an option for root canal medication after pulpectomy

Workshop report: Organ preservation strategies in advanced head and neck cancer—Current status and future directions Presented at the Fifth Research Workshop on the Biology, Prevention and Treatment of Head and Neck Cancer, McLean, Virginia, August 27–30, 1998. Head & Neck 21: 689–693, 1999

No abstract.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/35114/1/2_ftp.pd