Coordination of a bifunctional ligand to a rhodium(III) dimethyl complex : Lewis acidity enhancement by chelation

The addition of the ambiphilic compound (Me2PCH2AlMe2)2 (1) to Cp*RhMe2(DMSO) (DMSO ) dimethylsulfoxide) (2) gives Cp*RhMe2(PMe2CH2AlMe2‚DMSO) (3‚DMSO). The addition of Lewis acids (LA) such as La(dbm)3 (dbm ) dibenzoylmethane) and AlMe3 to a solution of complex 3‚DMSO gives a competition reaction that results in the formation of LA‚DMSO and Cp*RhMe2(PMe2CH2AlMe2) (3). When heated to 40 °C, complex 3 ionizes to a putative zwitterionic species, Cp*Rh+Me(PMe2CH2AlMe3 -) (3′), which is converted to [Cp*Rh(Me)(µ2 -η2 -Me2PCH2)]2 (4) irreversibly. Spin saturation transfer experiments demonstrated that the rate of the methyl abstraction by the alane moiety was 0.76 ( 0.09 s-1 , while the rate of abstraction of the methyl in Cp*RhMe2(PMe3) by AlMe3 was 0.10 ( 0.02 s-1 . The zwitterionic species 3′ could be trapped in solution by addition of PMe3 to afford both Cp*Rh+Me(PMe3)(Me2- PCH2AlMe3 -) (5) and [Cp*Rh+Me(PMe3)(Me2PCH2AlMe2)]AlMe4 - (6). When compound 1 was added to complex 3′, the formation of the zwitterionic complex Cp*Rh+Me(η2 -Me2PCH2Al-Me2CH2PMe2) (7) was observed

High clustering of acute HCV infections and high rate of associated STIs among Parisian HIV-positive male patients.

BACKGROUND: Increasing incidence of hepatitis C virus (HCV) infection in human immunodeficiency virus (HIV)-positive men having sex with men (MSM) has been described in recent years. Phylogenetic analyses of acute HCV infections were undertaken to characterize the dynamics during the epidemic in Paris, and associated sexually transmitted infections (STIs) were evaluated. METHODS: Sanger sequencing of polymerase gene was performed. Maximum likelihood phylogenies were reconstructed using FastTree 2.1 under a GTR+CAT model. Transmission chains were defined as clades with a branch probability ≥0.80 and intraclade genetic distances <0.02 nucleotide substitutions per sites. STIs detected ≤1 month before HCV diagnosis were considered. RESULTS: Among the 85 studied patients, at least 81.2% were MSM. Respectively, 47.6%, 39.0%, 11.0% and 2.4% were infected with genotypes 1a, 4d, 3a and 2k. At least 91.8% were co-infected with HIV. HCV re-infection was evidenced for 24.7% of patients and STIs for 20.0% of patients. Twenty-two transmission chains were identified, including 52 acute hepatitis C (11 pairs and 11 clusters from three to seven patients). CONCLUSIONS: These results revealed strong clustering of acute HCV infections. Thus, rapid treatment of both chronic and acute infections is needed among this population to decrease the prevalence of HCV, in combination with preventive behavioural interventions

Mémento 2 : Résidences 1999-2000

This richly illustrated catalogue documents the work of 35 artists who took part in six residencies (including two events - La Cueillette and La Ruche) that took place in 1999 and 2000 at Centre Est-Nord-Est. The centre’s director, F. Michel, describes the nature and purpose of the residencies as well as that of the catalogue : to reflect each participant’s experience. Includes brief comments by the artist on their work and on their stay. Text in French and English. Biographical notes

La radiologie en odontologie pédiatrique

La prise de cliché radiologique est indissociable de l'art dentaire notamment en odontologie pédiatrique. En effet chez les enfants il est important de suivre l'évolution des germes dentaires et seule la radiologie nous permet de le faire de manière sérieuse. L'enfant est un patient à part entière avec ses particularités, il n'est pas un " adulte de taille réduite ". Chaque technique a ses indications, ses avantages et ses limites, qu'il est important de bien connaître pour une utilisation adéquate. La réglementation en matière de radioprotection a changé ces dernières années avec l'arrivée des directives européennes. Il est important de la connaître pour mettre en application ces nouveautés. Tout cela permet une meilleure protection du patient, du personnel, mais aussi du praticien.REIMS-BU Santé (514542104) / SudocPARIS-BIUM (751062103) / SudocLILLE2-UFR Odontologie (593502202) / SudocSudocFranceF

Les documents de la chambre des cultures

Addressing the question of the document in the visual arts, Bénichou explores Thibault’s multidisciplinary practice (drawing, photography, installation, video), which blends artistic creation with experimental science. The author analyzes the artist’s career since 1995 and shows how she uses scientific documentation in projects that combine biology, fiction and ancient and modern scientific imagery. Texts in English and French. Biographical notes on artist and author. 11 bibl. ref

Enjeux du travail policier en milieux autochtones au Québec : La méthode d’analyse en groupe au service de la recherche de solutions

Bien que quelques auteurs se soient penchés sur la police autochtone, très peu, voire aucun, ne s’y sont intéressés dans une visée compréhensive et qualitative à partir du point de vue des policiers. Adoptant une perspective participative, cette étude vise à expérimenter la méthode d’analyse en groupe auprès de sept policiers issus de corps de police autochtones québécois pour documenter les principaux enjeux du travail en milieux autochtones et formuler des pistes de solutions adaptées aux réalités des communautés. Les résultats mettent notamment en évidence des enjeux liés à la non-reconnaissance de leur rôle au sein de la communauté autochtone et même policière, au manque de soutien organisationnel, à la proximité citoyenne et politique, à l’isolement social et professionnel, ainsi qu’à l’accessibilité lacunaire aux services partenaires pour soutenir leurs interventions. Ces défis se juxtaposent aux importants problèmes sociaux auxquels ces policiers font face quotidiennement. Cette démarche donne lieu à des pistes de solutions reposant sur la variété de représentations, lesquelles ont également permis l’élaboration d’un projet de recherche visant à approfondir la compréhension de la perception des policiers intervenant auprès des Premières Nations, Métis ou Inuits.Although some authors have studied Indigenous policing, very few, if any, have examined Indigenous policing from a comprehensive and qualitative approach and from the perspective of police officers. Adopting a participative method, this study used the group analysis method with seven police officers from Indigenous police forces in Quebec to document the main policing issues and formulate possible solutions adapted to the realities of the community. The results highlight, among other things, issues related to the non-recognition of the role of police within the Indigenous and even the police community, citizen and political proximity, social and professional isolation, and the lack of organizational support, as well as the lack of accessibility of partner services to support their interventions. These challenges are juxtaposed with the important social problems in the communities that police officers encounter daily. This approach gives rise to possible solutions based on the variety of representations and also led to the development of a research project aimed at gaining a better understanding of the perception of police officers who work with First Nations, Métis, or Inuit communities.A pesar de que varios autores se han interesado por la policía indígena, muy pocos, o ninguno, se han interesado desde una aproximación comprensiva y cualitativa, desde el punto de vista de los policías. Adoptando una perspectiva participativa, este proyecto busca experimentar el método de análisis de grupo con siete policías de diferentes fuerzas de policía indígena quebequense para documentar los dilemas principales del trabajo de los policías en medios autóctonos y formular pistas de solución adaptadas a las realidades de las comunidades. Los resultados evidencian dilemas ligados al no reconocimiento de su rol en la comunidad indígena y policial, a la falta de apoyo organizacional, a la proximidad ciudadana y política, al aislamiento profesional, así como al acceso insuficiente de los servicios de los socios en apoyo a sus intervenciones. Estos desafíos se yuxtaponen a las problemáticas sociales importantes enfrentadas por estos policías en su vida diaria. Este método lleva a proponer pistas de solución sustentadas en la diversidad de representaciones, las cuales permitieron, igualmente, la elaboración de un proyecto de investigación que buscaba profundizar la comprensión de la percepción de los policías que intervienen con las Primeras Naciones, los Mestizos, o los Inuit