Protist predation can favour cooperation within bacterial species

Here, we studied how protist predation affects cooperation in the opportunistic pathogen bacterium Pseudomonas aeruginosa, which uses quorum sensing (QS) cell-to-cell signalling to regulate the production of public goods. By competing wild-type bacteria with QS mutants (cheats), we show that a functioning QS system confers an elevated resistance to predation. Surprisingly, cheats were unable to exploit this resistance in the presence of cooperators, which suggests that resistance does not appear to result from activation of QS-regulated public goods. Instead, elevated resistance of wild-type bacteria was related to the ability to form more predation-resistant biofilms. This could be explained by the expression of QS-regulated resistance traits in densely populated biofilms and floating cell aggregations, or alternatively, by a pleiotropic cost of cheating where less resistant cheats are selectively removed from biofilms. These results show that trophic interactions among species can maintain cooperation within species, and have further implications for P. aeruginosa virulence in environmental reservoirs by potentially enriching the cooperative and highly infective strains with functional QS system

A statistical approach to identify superluminous supernovae and probe their diversity

We investigate the identification of hydrogen-poor superluminous supernovae (SLSNe I) using a photometric analysis, without including an arbitrary magnitude threshold. We assemble a homogeneous sample of previously classified SLSNe I from the literature, and fit their light curves using Gaussian processes. From the fits, we identify four photometric parameters that have a high statistical significance when correlated, and combine them in a parameter space that conveys information on their luminosity and color evolution. This parameter space presents a new definition for SLSNe I, which can be used to analyse existing and future transient datasets. We find that 90% of previously classified SLSNe I meet our new definition. We also examine the evidence for two subclasses of SLSNe I, combining their photometric evolution with spectroscopic information, namely the photospheric velocity and its gradient. A cluster analysis reveals the presence of two distinct groups. `Fast' SLSNe show fast light curves and color evolution, large velocities, and a large velocity gradient. `Slow' SLSNe show slow light curve and color evolution, small expansion velocities, and an almost non-existent velocity gradient. Finally, we discuss the impact of our analyses in the understanding of the powering engine of SLSNe, and their implementation as cosmological probes in current and future surveys.Comment: 16 pages, 9 figures, accepted by ApJ on 23/01/201

Soft X-ray Excess in the Coma Cluster from a Cosmic Axion Background

We show that the soft X-ray excess in the Coma cluster can be explained by a cosmic background of relativistic axions converting into photons in the cluster magnetic field. We provide a detailed self-contained review of the cluster soft X-ray excess, the proposed astrophysical explanations and the problems they face, and explain how a 0.1-1 keV axion background naturally arises at reheating in many string theory models of the early universe. We study the morphology of the soft excess by numerically propagating axions through stochastic, multi-scale magnetic field models that are consistent with observations of Faraday rotation measures from Coma. By comparing to ROSAT observations of the 0.2-0.4 keV soft excess, we find that the overall excess luminosity is easily reproduced for $g_{a\gamma\gamma} \sim 2 \times 10^{-13}$ GeV$^{-1}$. The resulting morphology is highly sensitive to the magnetic field power spectrum. For Gaussian magnetic field models, the observed soft excess morphology prefers magnetic field spectra with most power in coherence lengths on ${\cal O}(3 {\rm ~kpc})$ scales over those with most power on ${\cal O}(12 {\rm ~kpc})$ scales. Within this scenario, we bound the mean energy of the axion background to $50\, {\rm eV}\lesssim \langle E_a \rangle \lesssim 250\, {\rm eV}$, the axion mass to $m_a \lesssim 10^{-12}\,\hbox{eV}$, and derive a lower bound on the axion-photon coupling $g_{a\gamma\gamma} \gtrsim \sqrt{0.5/\Delta N_{\rm eff}}\, 1.4 \times 10^{-13}$ GeV$^{-1}$.Comment: 43 pages, 11 figure

Temporal trend in the transfer of Sellafield-derived 14C into different size fractions of the carbonate component of NE Irish Sea sediment

From 1994 onwards, 14C discharges from the Sellafield nuclear fuel reprocessing plant have been made largely to the Northeast Irish Sea. They represent the largest contributor to UK and European populations of the collective dose commitment derived from the entire nuclear industry discharges. Consequently, it is important to understand the long-term fate of 14C in the marine environment. Research undertaken in 2000 suggested that the carbonate component of Northeast Irish Sea sediments would increase in 14C activity as mollusc shells, which have become enriched in Sellafield-derived 14C, are broken down by physical processes including wave action and incorporated into intertidal and sub-tidal sediments. The current study, undertaken in 2011, tested this hypothesis. The results demonstrate significant increases in 14C enrichments found in whole mussel shells compared to those measured in 2000. Additionally, in 2000, there was an enrichment above ambient background within only the largest size fraction (>500 μm) of the intertidal inorganic sediment at Nethertown and Flimby (north of Sellafield). In comparison, the present study has demonstrated 14C enrichments above ambient background in most size fractions at sites up to 40 km north of Sellafield, confirming the hypothesis set out more than a decade ago

Analogue Cosmological Particle Creation: Quantum Correlations in Expanding Bose Einstein Condensates

We investigate the structure of quantum correlations in an expanding Bose Einstein Condensate (BEC) through the analogue gravity framework. We consider both a 3+1 isotropically expanding BEC as well as the experimentally relevant case of an elongated, effectively 1+1 dimensional, expanding condensate. In this case we include the effects of inhomogeneities in the condensate, a feature rarely included in the analogue gravity literature. In both cases we link the BEC expansion to a simple model for an expanding spacetime and then study the correlation structure numerically and analytically (in suitable approximations). We also discuss the expected strength of such correlation patterns and experimentally feasible BEC systems in which these effects might be detected in the near future.Comment: Reference adde

Nitrogen Mineralization from Root Residues of Subterranean Clover and Lucerne

To understand why crops grown in the first or second year after lucerne (Medicago sativa L.) yielded less than crops grown after subterranean clover (Trifolium subterraneum L.) despite greater nitrogen (N) fixation by the lucerne, we studied the N mineralization patterns of their root residues in soil incubation assays. Fine roots of both species produced more mineral N than the control soil with no root residues. In contrast, coarse roots mineralized less N than the control soil. These differences in N mineralization were not explained by the physical size and therefore surface area differences between fine and coarse roots. Rather, the differences in N mineralization were explained by differences in the carbon to nitrogen ratio (C:N) of fine and coarse roots. Fine roots of both species had a C:N of about 11, while the C:N of coarse roots ranged from 28 to 37. Empirical evidence suggests that a mineralization / immobilization threshold occurs at a C:N of 20 to 30, and these results are in accordance with this interpretation. However, subterranean clover had mainly fine roots giving a weighted average C:N of 19 for the whole root system, while lucerne had mainly coarse roots giving an average C:N of 26, suggesting that root residues of subterranean clover result in a net mineralization of N while lucerne roots cause a net immobilization of N

Functional network changes and cognitive control in schizophrenia

Cognitive control is a cognitive and neural mechanism that contributes to managing the complex demands of day-to-day life. Studies have suggested that functional impairments in cognitive control associated brain circuitry contribute to a broad range of higher cognitive deficits in schizophrenia. To examine this issue, we assessed functional connectivity networks in healthy adults and individuals with schizophrenia performing tasks from two distinct cognitive domains that varied in demands for cognitive control, the RiSE episodic memory task and DPX goal maintenance task. We characterized general and cognitive control-specific effects of schizophrenia on functional connectivity within an expanded frontal parietal network (FPN) and quantified network topology properties using graph analysis. Using the network based statistic (NBS), we observed greater network functional connectivity in cognitive control demanding conditions during both tasks in both groups in the FPN, and demonstrated cognitive control FPN specificity against a task independent auditory network. NBS analyses also revealed widespread connectivity deficits in schizophrenia patients across all tasks. Furthermore, quantitative changes in network topology associated with diagnostic status and task demand were observed. The present findings, in an analysis that was limited to correct trials only, ensuring that subjects are on task, provide critical insights into network connections crucial for cognitive control and the manner in which brain networks reorganize to support such control. Impairments in this mechanism are present in schizophrenia and these results highlight how cognitive control deficits contribute to the pathophysiology of this illness

Abnormal phosphomonoester signals in 31P MR spectra from patients with hepatic lymphoma. A possible marker of liver infiltration and response to chemotherapy.

Hepatic infiltration by lymphoma can be difficult to detect by conventional methods. We have studied 22 patients in vivo 31P magnetic resonance spectroscopy of the liver and compared the results with the clinical staging and assessment of liver involvement by computed tomography (CT), ultrasound (US), and liver function tests (LFTs). We find that the phosphomonoester (PME) to ATP, and the PME to Pi ratios are the best indication of liver involvement as in all the patients with liver involvement apparent on CT or US, these ratios were elevated (greater than 2 s.d. above the control mean). Of the patients with deranged LFTs but normal CT or US, five out of nine showed increased PME/ATP and PME/Pi ratios, and in the patients with normal LFTs and normal CT or US, three out of eight patients had raised PME ratios. Extracts of lymphomatous lymph nodes contain high concentrations of phosphoethanolamine which suggests that this compound is responsible for the increase in the PME peak. Eleven patients were studied again after chemotherapy, and those with initially raised PME/ATP and PME/Pi ratios all showed a decrease in these ratios towards normal. The patients with initially normal ratios showed no changes

Playing for high stakes: Findings from the Irish neighbourhood play research project and their implications for education

The Irish Neighbourhood Play Research Project included almost 1700 families and 240 communities throughout Ireland. The findings hold clear implications for educational policy and practice. Using surveys, interviews and naturalistic observation, data was secured on how children in modern Ireland aged 0 - 15 are playing. An all-island approach was taken incorporating cities, towns and rural areas across a variety of socio-economic groupings. Interesting findings arose from the data relating to generational differences in levels of freedom, play, exercise, engagement with risk, with nature, with scheduled/timetabled extracurricular activities, with homework, with electronics, with creative activities and with traditional play types and games. Differences in play choices and experiences were also evident across socio-economic groupings, community types, gender lines, age ranges and housing types. This paper presents the data and asks what it means within a framework of educational implication. Most importantly: what can education do to redress these implications? Innovations in pedagogy and policy are required to meet the educational challenges implicit within this data. This ground breaking research on the changing face of childhood points clearly to the need for collaborative, co- participative, democratic, empowering and playful pedagogies and educational policies which support them