Analysis of the influence of the anisotropy induced by cold rolling on duplex and super-austenitic stainless steels

This report contains the results obtained from the mechanical characterization tests carried out on two different stainless steel (duplex 6%Ni, 22%Cr and super-austenitic 31%Ni, 28%Cr) used for the manufacturing of pipes which are employed in the oil production. The activity has been performed in order to evaluate the effects of anisotropy, induced by cold rolling, on the mechanical characteristics of the investigated steels, measured in the three main directions. Considering the small size of the component, the method and the specimens used for the tests were not the standard one. The procedure carried out provided the strain measurement of the specimen during testing by means of resistive strain gages, bonded on the specimens

Scar-Free Laparoscopy in BRCA-Mutated Women

Background and Objectives: BRCA 1 and 2 mutations have a cumulative risk of developing ovarian cancer at 70 years of 41% and 15%, respectively, while a cumulative risk of breast cancer by 80 years of age was 72% for BRCA1 mutation carriers and 69% for BRCA2 mutation carriers. The NCCN recommends risk-reducing salpingo-oophorectomy (RRSO), typically between 35 and 40 years, and upon completion of childbearing in BRCA1 mutation, while it is reasonable to delay RRSO for management of ovarian cancer risk until age 40–45 years in patients with BRCA2. In recent years there have been two main lines of evolution in laparoscopy. The former concerning the development of a single-site laparoscopic and the latter concerning the miniaturisation of laparoscopic instruments (mini/micro-laparoscopy). Materials and Methods: In this case report, we show our experience in prophylactic adnexectomy, on a mutated-BRCA patient, using the MiniLap® percutaneous surgical system. Results: This type of technique is safe and effective and does not require a particular learning curve compared to single-port laparoscopy. Conclusions: The considerable aesthetic advantage of the scars, we believe, albeit to a lesser extent, is useful to find in these patients burdened by an important stress loa

Proceedings of the 17th national conference of Italian group of fracture

4+319hal.;24c

Role of blue dye for sentinel lymph node detection in early endometrial cancer

Background: Sentinel Lymphonode analysis has become a barely new and innovative way to treat early stages of endometrial cancer (Ballester et al., Lancet Oncol 469\ue2\u80\u93476, 2011; Buda et al., Ann Surg Oncol 2975-81, 2016). Indocyanine green cervical injection is considered gold standard for mapping nodes\ue2\u80\u99 drainage. Blue dye is used as a valid alternative in many centers, due to the lower cost of execution. The objective of this video is to prove that methylene blue dye\ue2\u80\u99s cervical injection is a valid and \ue2\u80\u9clow-cost\ue2\u80\u9d method to obtain mapping of lymphatic drainage in patient with early endometrial cancer. Methods: Fifty-four-year old women, with a recent diagnosis of endometrial cancer IA G2, we performed a radical Hysterectomy type A. We diluted in equal proportions the blue dye and saline and injected 1\uc2\ua0cl in depth and 1\uc2\ua0cl on the surface of the cervix, at 3 o\ue2\u80\u99clock and 9 o\ue2\u80\u99clock. After 20\uc2\ua0min, it was shown with precision the lymphatic drainage until the first lymph node station from both sides. Results: One external iliac lymph node and one obturator were resected on the left side and one external iliac on the right side. On histological analysis, none of the lymph nodes had any location of metastasis, neither micro-metastasis. Myometrial infiltration was 8/19\uc2\ua0mm. Conclusions: Blue dye cervical injection is a \ue2\u80\u9clow-cost\ue2\u80\u9d, safe, and satisfactory procedure to point out Sentinel Lymph Node of uterus drainage. Other tracers, such as indocyanine green, are widely used in gynecological oncology, but with a higher cost of the product and the needing of a dedicated optical filter to be shown on human view

We are What We Eat: Impact of Food from Short Supply Chain on Metabolic Syndrome

Food supply in the Mediterranean area has been recently modified by big retail distribution; for instance, industrial retail has favored shipments of groceries from regions that are intensive producers of mass food, generating a long supply chain (LSC) of food that opposes short supply chains (SSCs) that promote local food markets. However, the actual functional role of food retail and distribution in the determination of the risk of developing metabolic syndrome (MetS) has not been studied hitherto. The main aim of this study was to test the effects of food chain length on the prevalence of MetS in a population accustomed to the Mediterranean diet. We conducted an observational study in Southern Italy on individuals adhering to the Mediterranean diet. We examined a total of 407 subjects (41% females) with an average age of 56 ± 14.5 years (as standard deviation) and found that being on the Mediterranean diet with a SSC significantly reduces the prevalence of MetS compared with the LSC (SSC: 19.65%, LSC: 31.46%; p: 0.007). Our data indicate for the first time that the length of food supply chain plays a key role in determining the risk of MetS in a population adhering to the Mediterranean diet

Laparoscopic Approach for Shull Repair of Pelvic Floor Defects

Study Objective: To prove the feasibility of the Shull technique by a laparoscopic approach in a patient affected by pelvic organ prolapse (POP) with apical loss of support. Design: A step-by-step video demonstration (Canadian Task Force classification III). Setting: University hospital. Ethics Committee ruled that approval was not required for this study. Patient: A 53-year-old woman with a POP-Q stage IV, left ovarian cyst. Intervention: Laparoscopic uterosacral ligament suspension. Measurements and Main Results: According to the National Health and Nutrition Examination Survey, approximately 3% of women in the United States report symptoms linked to POP, with approximately 300 000 POP surgeries each year in the United States. More recent studies show a lower reoperation rate of approximately 6% to 30%, and this lower reoperation rate may reflect improvement in surgical technique and POP surgery that includes suspension of the vaginal apex, which is associated with a decreased reoperation rate, commonly done by vaginal vault suspension to uterosacral ligaments. Suturing the apex to the high (proximal) portion of each uterosacral ligament is more commonly performed vaginally, although abdominal and laparoscopic approaches are suitable. It represents a modification of the uterosacral ligament suspension procedure described by Shull. A 53-year-old woman with a POP-Q stage IV, left ovarian cyst and an "elongatio colli" underwent a total hysterectomy and bilateral ovariectomy with vaginal dome uterosacral ligament suspension performed laparoscopically. The total operating time was 80 minutes, with a blood loss volume of less than 50 mL. The patient was hospitalized for 2 days. There were no postoperative complications in 30 days. Conclusion: The Shull laparoscopic surgery for advance POP with reconstruction of the anterior compartment is technically feasible

Vitamin D, parathyroid hormone and cardiovascular risk: The good, the bad and the ugly

25-Hydroxyvitamin D insufficiency and increased cardiovascular risk (CVR) association is still debated. The vitamin D (VitD)-dependent parathyroid hormone (PTH) is considered as the possible actuator of VitD effects on CVR. To investigate the association of CVR, PTH and VitD, we carried out blood pressure measurements and blood samples and collected information on dietary habits, anamnestic, clinical and metabolic data of 451 participants in the Salerno area (Southern Italy) during the World Hypertension Day (17 May). CVR was calculated according to the Framingham CVR charts. The overall population mean age was 51.6±0.7 years, and female sex was slightly prevalent (55%). VitD deficiency (<20ng/ml) was most frequent (59.7%). In this population, VitD and CVR did not correlate. VitD and PTH inversely correlated (r=-0.265, P<0.001) as expected. PTH was in direct correlation (r=0.225, P<0.001) with CVR. Elevated PTH (75 percentile; â\u89¥49.5pg/ml) levels identify a population with higher CVR (11.8±0.5 vs. 8.5±0.3, P<0.001). In a multivariate analysis, both age and PTH correlate to CVR, but not VitD. In conclusion, VitD does not directly affect CVR in the overall population. Rather, increased PTH might be a better predictor of CVR