Why carers use adult day respite: a mixed method case study

BACKGROUND: We need to improve our understanding of the complex interactions between family carers’ emotional relationships with care-recipients and carers use of support services. This study assessed carer’s expectations and perceptions of adult day respite services and their commitment to using services. METHODS: A mixed-method case study approach was used with psychological contract providing a conceptual framework. Data collection was situated within an organisational case study, and the total population of carers from the organisation’s day respite service were approached. Fifty respondents provided quantitative and qualitative data through an interview survey. The conceptual framework was expanded to include Maslow’s hierarchy of needs during analysis. RESULTS: Carers prioritised benefits for and experiences of care-recipients when making day respite decisions. Respondents had high levels of trust in the service and perceived that the major benefits for care-recipients were around social interaction and meaningful activity with resultant improved well-being. Carers wanted day respite experiences to include all levels of Maslow’s hierarchy of needs from the provision of physiological care and safety through to the higher levels of belongingness, love and esteem. CONCLUSION: The study suggests carers need to trust that care-recipients will have quality experiences at day respite. This study was intended as a preliminary stage for further research and while not generalizable it does highlight key considerations in carers’ use of day respite services

Physical and biological controls on fine sediment transport and storage in rivers

Excess fine sediment, comprising particles <2 mm in diameter, is a major cause of ecological degradation in rivers. The erosion of fine sediment from terrestrial or aquatic sources, its delivery to the river, and its storage and transport in the fluvial environment are controlled by a complex interplay of physical, biological and anthropogenic factors. Whilst the physical controls exerted on fine sediment dynamics are relatively well-documented, the role of biological processes and their interactions with hydraulic and physico-chemical phenomena has been largely overlooked. The activities of biota, from primary producers to predators, exert strong controls on fine sediment deposition, infiltration and resuspension. For example, extracellular polymeric substances (EPS) associated with biofilms increase deposition and decrease resuspension. In lower energy rivers, aquatic macrophyte growth and senescence are intimately linked to sediment retention and loss, whereas riparian trees are dominant ecosystem engineers in high energy systems. Fish and invertebrates also have profound effects on fine sediment dynamics through activities that drive both particle deposition and erosion depending on species composition and abiotic conditions. The functional traits of species present will determine not only these biotic effects but also the responses of river ecosystems to excess fine sediment. We discuss which traits are involved and put them into context with spatial processes that occur throughout the river network. Whilst strides towards better understanding of the impacts of excess fine sediment have been made, further progress to identify the most effective management approaches is urgently required through close communication between authorities and scientists

An Analysis of the Characteristics and Practices of Selected Florida Small Livestock Producers: A Focus on Production and Processing

The study assessed the characteristics and practices of small livestock producers, emphasizing production and processing. Data were obtained from a convenience sample of seventy small producers from selected counties in Florida, and analyzed using descriptive statistics, including chi-square tests. The socioeconomic characteristics showed that part-time producers, White producers, middle-aged producers, fairly educated producers, and moderate-income producers dominated the group. A majority of the producers practiced rotational grazing, fed a combination of forage and concentrate, and less than half conducted soil tests regularly. Moreover, over half had parasite problems and treated them primarily with anthelmintics. Nearly all producers sold animals live, implying very little processing. Therefore, some processing could be encouraged as value-added products fetch more than raw products. The chi-square tests also revealed that household income, race, farming status, and gender had statistically significant relationships with selected production characteristics. Keywords: Livestock Producers, Small Producers, Characteristics and Practices, Production and Processin

An Analysis of the Characteristics and Practices of Selected Florida Small Livestock Producers: A Focus on Economics and Marketing

Issues regarding economics and marketing are of importance to small livestock producers, who produce and sell locally or regionally. This study, thus, assessed the characteristics and practices of selected Florida small livestock producers, emphasizing economics and marketing. Data were collected from a convenience sample of seventy small producers from several Florida counties, and were analyzed using descriptive statistics, including chi-square tests. The findings showed that there were many more: full-time producers; producers with at least a two-year/technical degree, and producers with at, least, a $40,000 annual household income. Most had been farming more than fifteen years, on at least 50 acres, and had small herds. Furthermore, very few of them made profits; they mainly sold animals live on-farm or at the auction/stockyard, and many of them kept records. Chi-square tests showed that gender, age, education, and household income had statistically significant effects on selected marketing characteristics. The findings suggest that educational programs that emphasize economic and marketing issues should be taken into consideration when designing programs for small producers in the study area. Keywords: Livestock Producers, Small Producers, Characteristics and Practices, Economics and Marketin

The Impact of Socioeconomic Factors on Selected Practices by Small Livestock Producers in Florida

Socioeconomic factors could affect the practices of small livestock producers who produce and sell locally or regionally. Yet, there is limited research on the issue in the Southeastern U.S., for example, Florida. Thus, this study assessed the impact of socioeconomic factors on practices of small livestock producers in Florida. The data were obtained from a sample of seventy producers from several counties in Florida, and were analyzed using descriptive statistics and logistic regression analysis. The results showed that a majority practiced rotational grazing; did not test soil regularly; had parasite problems; did not use veterinary services, and practiced record keeping. Further, the binary logistic regression analyses showed that selected socioeconomic factors had statistically significant effects on selected practices. For instance, gender had a statistically significant effect on soil testing; household income had a statistically significant effect on parasite problem; gender had a statistically significant effect on the use of veterinary services; and farming status, race/ethnicity, education, and household income had statistically significant effects on record keeping. The findings suggest that socioeconomic factors may be important in producers adopting practices. Keywords: Socioeconomic Factors, Selected Practices, Farm Practices, Small Livestock Producers, Small Producer

A Comparative Analysis of Selected Producer Characteristics and Production Practices of Small Livestock Producers in Three Southeastern States of The US

It is germane to know the characteristics and practices of small livestock producers in order to assist them; however, there are a paucity of investigations on the subject in the Southeastern US. Thus, this study assessed selected producer characteristics and production practices of small livestock producers in three Southeastern States. The data were collected from three samples of producers in several counties of Alabama, Georgia, and Florida, and were analyzed using descriptive statistics. The results showed that, a majority of producers practiced rotational grazing, had parasite problems, quarantined newly acquired animals, and used veterinary services. Additionally, a majority sold their animals live, and many kept records manually or on a computer. The findings indicate commonalities across the three states, in terms of rotational grazing, parasite problems, quarantine, how animals are sold, and record keeping. There is a need to assist small producers in certain aspects of production practices and in value-added processe

A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.

The identification of the genes associated with chromosomal translocation breakpoints has fundamentally changed understanding of the molecular basis of hematological malignancies. By contrast, the study of chromosomal deletions has been hampered by the large number of genes deleted and the complexity of their analysis. We report the generation of a mouse model for human 5q- syndrome using large-scale chromosomal engineering. Haploinsufficiency of the Cd74-Nid67 interval (containing Rps14, encoding the ribosomal protein S14) caused macrocytic anemia, prominent erythroid dysplasia and monolobulated megakaryocytes in the bone marrow. These effects were associated with defective bone marrow progenitor development, the appearance of bone marrow cells expressing high amounts of the tumor suppressor p53 and increased bone marrow cell apoptosis. Notably, intercrossing with p53-deficient mice completely rescued the progenitor cell defect, restoring common myeloid progenitor and megakaryocytic-erythroid progenitor, granulocyte-monocyte progenitor and hematopoietic stem cell bone marrow populations. This mouse model suggests that a p53-dependent mechanism underlies the pathophysiology of the 5q- syndrome

Delayed Imitation of Lipsmacking Gestures by Infant Rhesus Macaques (Macaca mulatta)

Human infants are capable of accurately matching facial gestures of an experimenter within a few hours after birth, a phenomenon called neonatal imitation. Recent studies have suggested that rather than being a simple reflexive-like behavior, infants exert active control over imitative responses and ‘provoke’ previously imitated gestures even after a delay of up to 24 h. Delayed imitation is regarded as the hallmark of a sophisticated capacity to control and flexibly engage in affective communication and has been described as an indicator of innate protoconversational readiness. However, we are not the only primates to exhibit neonatal imitation, and delayed imitation abilities may not be uniquely human. Here we report that 1-week-old infant rhesus macaques (Macaca mulatta) who show immediate imitation of a lipsmacking gesture also show delayed imitation of lipsmacking, facilitated by a tendency to refrain from lipsmacking toward a still face during baseline measurements. Individual differences in delayed imitation suggest that differentially matured cortical mechanisms may be involved, allowing some newborns macaques to actively participate in communicative exchanges from birth. Macaque infants are endowed with basic social competencies of intersubjective communication that indicate cognitive and emotional commonality between humans and macaques, which may have evolved to nurture an affective mother-infant relationship in primates

Research Priorities in CKD: Report of a National Workshop Conducted in Australia

Research aims to improve health outcomes for patients. However, the setting of research priorities is usually performed by clinicians, academics, and funders, with little involvement of patients or caregivers and using processes that lack transparency. A national workshop was convened in Australia to generate and prioritize research questions in chronic kidney disease (CKD) among diverse stakeholder groups. Patients with CKD (n = 23), nephrologists/surgeons (n = 16), nurses (n = 8), caregivers (n = 7), and allied health professionals and researchers (n = 4) generated and voted on intervention questions across 4 treatment categories: CKD stages 1 to 5 (non–dialysis dependent), peritoneal dialysis, hemodialysis, and kidney transplantation. The 5 highest ranking questions (in descending order) were as follows: How effective are lifestyle programs for preventing deteriorating kidney function in early CKD? What strategies will improve family consent for deceased donor kidney donation, taking different cultural groups into account? What interventions can improve long-term post-transplant outcomes? What are effective interventions for post hemodialysis fatigue? How can we improve and individualize drug therapy to control post-transplant side effects? Priority questions were focused on prevention, lifestyle, quality of life, and long-term impact. These prioritized research questions can inform funding agencies, patient/consumer organizations, policy makers, and researchers in developing a CKD research agenda that is relevant to key stakeholders

Pathogenesis of Candida albicans Infections in the Alternative Chorio-Allantoic Membrane Chicken Embryo Model Resembles Systemic Murine Infections

Alternative models of microbial infections are increasingly used to screen virulence determinants of pathogens. In this study, we investigated the pathogenesis of Candida albicans and C. glabrata infections in chicken embryos infected via the chorio-allantoic membrane (CAM) and analyzed the virulence of deletion mutants. The developing immune system of the host significantly influenced susceptibility: With increasing age, embryos became more resistant and mounted a more balanced immune response, characterized by lower induction of proinflammatory cytokines and increased transcription of regulatory cytokines, suggesting that immunopathology contributes to pathogenesis. While many aspects of the chicken embryo response resembled murine infections, we also observed significant differences: In contrast to systemic infections in mice, IL-10 had a beneficial effect in chicken embryos. IL-22 and IL-17A were only upregulated after the peak mortality in the chicken embryo model occurred; thus, the role of the Th17 response in this model remains unclear. Abscess formation occurs frequently in murine models, whereas the avian response was dominated by granuloma formation. Pathogenicity of the majority of 15 tested C. albicans deletion strains was comparable to the virulence in mouse models and reduced virulence was associated with significantly lower transcription of proinflammatory cytokines. However, fungal burden did not correlate with virulence and for few mutants like bcr1Δ and tec1Δ different outcomes in survival compared to murine infections were observed. C. albicans strains locked in the yeast stage disseminated significantly more often from the CAM into the embryo, supporting the hypothesis that the yeast morphology is responsible for dissemination in systemic infections. These data suggest that the pathogenesis of C. albicans infections in the chicken embryo model resembles systemic murine infections but also differs in some aspects. Despite its limitations, it presents a useful alternative tool to pre-screen C. albicans strains to select strains for subsequent testing in murine models