145 research outputs found

    Global Outsourcing: A Study of Student Attitudes

    Get PDF
    The practice of global outsourcing by U.S.A. companies is frequently the source of heated debate. Recently a Wall Street Journal-NBC News poll found that 86% of Americans believe that outsourcing is the number one factor contributing to the country’s continuing economic distress. This study presents the results of a survey designed to assess the attitudes toward global outsourcing among business students and non business students at a large regional university in the Southeast U.S.A. A survey of attitudes toward global outsourcing was administered to 284 undergraduate and graduate students. Descriptive statistics, frequencies and MANOVA methods were used to analyze the data collected. Statistically significant differences with attitudes were found among the students\u27 level of knowledge, age, gender, major, and classification. The results indicate business majors are more positive toward global outsourcing than are non-business majors. Another finding is that older students (\u3e25) and MBA students are more pessimistic toward global outsourcing. Those “older” and MBA’s were mostly concerned with the impact of such outsourcing on jobs. Implications for teaching international business are discussed

    Global Outsourcing: A Study of Student Attitudes

    Get PDF
    This paper presents the results of a survey designed to assess students’ attitudes toward global outsourcing. A survey of attitudes toward outsourcing jobs abroad was administered to 284 undergraduate and graduate university students. Descriptive statistics, frequencies and MANOVA methods were used to analyze the data collected. Statistically significant differences with attitudes were found among the students’ level of knowledge, age, gender, major, and classification. Essentially what was learned is that overall, business majors are more positive toward global outsourcing than are non-business majors. However, it was also learned that older students (\u3e25) and MBA students are more pessimistic toward global outsourcing. Those “older” and MBA’s were mostly concerned with the impact of such outsourcing on jobs. Implications for teaching international business are also discussed

    The correlation-consistent composite approach: Application to the G3/99 test set

    Get PDF
    Article discussing research on the correlation consistent composite approach (ccCA) and an application to the G3/99 test set

    Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

    Get PDF
    We performed a meta-analysis of five genome-wide association studies to identify common variants influencing colorectal cancer (CRC) risk comprising 8,682 cases and 9,649 controls. Replication analysis was performed in case-control sets totaling 21,096 cases and 19,555 controls. We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 × 10(-10)), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 × 10(-10)) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 × 10(-10)) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC.Swedish Research Council et al.Manuscrip

    The history of Coast Salish “woolly dogs” revealed by ancient genomics and Indigenous Knowledge

    Get PDF
    Ancestral Coast Salish societies in the Pacific Northwest kept long-haired “woolly dogs” that were bred and cared for over millennia. However, the dog wool–weaving tradition declined during the 19th century, and the population was lost. In this study, we analyzed genomic and isotopic data from a preserved woolly dog pelt from “Mutton,” collected in 1859. Mutton is the only known example of an Indigenous North American dog with dominant precolonial ancestry postdating the onset of settler colonialism. We identified candidate genetic variants potentially linked with their distinct woolly phenotype. We integrated these data with interviews from Coast Salish Elders, Knowledge Keepers, and weavers about shared traditional knowledge and memories surrounding woolly dogs, their importance within Coast Salish societies, and how colonial policies led directly to their disappearance

    A prenylated dsRNA sensor protects against severe COVID-19

    Get PDF
    Inherited genetic factors can influence the severity of COVID-19, but the molecular explanation underpinning a genetic association is often unclear. Intracellular antiviral defenses can inhibit the replication of viruses and reduce disease severity. To better understand the antiviral defenses relevant to COVID-19, we used interferon-stimulated gene (ISG) expression screening to reveal that OAS1, through RNase L, potently inhibits SARS-CoV-2. We show that a common splice-acceptor SNP (Rs10774671) governs whether people express prenylated OAS1 isoforms that are membrane-associated and sense specific regions of SARS-CoV-2 RNAs, or only express cytosolic, nonprenylated OAS1 that does not efficiently detect SARS-CoV-2. Importantly, in hospitalized patients, expression of prenylated OAS1 was associated with protection from severe COVID-19, suggesting this antiviral defense is a major component of a protective antiviral response

    stairs and fire

    Get PDF
    • 

    corecore