Alcohol Prohibition and Cirrhosis

This paper uses state-level data on cirrhosis death rates to examine the impact of state prohibitions, pre-1920 federal anti-alcohol policies, and constitutional prohibition on cirrhosis State prohibitions had a minimal impact on cirrhosis, especially during the pre-1920 period. Pre-1920 federal anti-alcohol policies may have contributed to the decline in cirrhosis that occurred before 1920, although other factors were likely substantial influences as well. Constitutional prohibition reduced cirrhosis by about 10-20 percent.

What Do Economists Know About Crime?

In this paper we evaluate what economists have learned over the past 40 years about the determinants of crime. We base our evaluation on two kinds of evidence: an examination of aggregate data over long time periods and across countries, and a critical review of the literature. We argue that economists know little about the empirically relevant determinants of crime. Even hypotheses that find some support in U.S. data for recent decades are inconsistent with data over longer horizons or across countries. This conclusion applies both to policy variables like arrest rates or capital punishment and to less conventional factors such as abortion or gun laws. The hypothesis that drug prohibition generates violence, however, is generally consistent with the long times-series and cross-country facts. This analysis is also consistent with a broader perspective in which government policies that affect the nature and amount of dispute resolution play an important role in determining violence.

Charter School Funding: Dispelling Myths about EMOs, Expenditure Patterns, & Nonpublic Dollars

Three decades after the first charter school law passed in the United States, myths about these public schools not only persist but continue to fuel strong claims and divisive debates. Commentators point to education management organizations (EMOs), for-profit organizations which manage or operate a network of charter schools, as examples of private entities supposedly profiting off public education. In this report, we dispel three common myths about charter schools and their funding, spending, and management (see box). We draw upon comprehensive school funding data collected from traditional public schools (TPS) and public charter schools in 18 cities during fiscal year (FY) 2018. In a November 2020 report, Charter School Funding: Inequity Surges in the Cities, we demonstrated that the public charter schools in those 18 cities received on average one-third less funding than their respective TPS. Here we drill down deeply into those data to test claims about public charter schools and the myths surrounding them

Correction: Expanding the clinical phenotype of individuals with a 3-bp in-frame deletion of the NF1 gene (c.2970_2972del): an update of genotype–phenotype correlation

n/

Expanding the clinical phenotype of individuals with a 3-bp in-frame deletion of the NF1 gene (c.2970_2972del): an update of genotype–phenotype correlation

Purpose: Neurofibromatosis type 1 (NF1) is characterized by a highly variable clinical presentation, but almost all NF1-affected adults present with cutaneous and/or subcutaneous neurofibromas. Exceptions are individuals heterozygous for the NF1 in-frame deletion, c.2970_2972del (p.Met992del), associated with a mild phenotype without any externally visible tumors. Methods: A total of 135 individuals from 103 unrelated families, all carrying the constitutional NF1 p.Met992del pathogenic variant and clinically assessed using the same standardized phenotypic checklist form, were included in this study. Results: None of the individuals had externally visible plexiform or histopathologically confirmed cutaneous or subcutaneous neurofibromas. We did not identify any complications, such as symptomatic optic pathway gliomas (OPGs) or symptomatic spinal neurofibromas; however, 4.8% of individuals had nonoptic brain tumors, mostly low-grade and asymptomatic, and 38.8% had cognitive impairment/learning disabilities. In an individual with the NF1 constitutional c.2970_2972del and three astrocytomas, we provided proof that all were NF1-associated tumors given loss of heterozygosity at three intragenic NF1 microsatellite markers and c.2970_297

We thank Sam Peltzman and Kevin Lang for useful comments. Alcohol Prohibition and Cirrhosis

This paper uses state-level data on cirrhosis death rates to examine the impact of state prohibitions, pre-1920 federal anti-alcohol policies, and constitutional prohibition on cirrhosis. State prohibitions had a minimal impact on cirrhosis, especially during the pre-1920 period. Pre-1920 federal anti-alcohol policies may have contributed to the decline in cirrhosis that occurred before 1920, although other factors were likely substantial influences as well. Constitutional prohibition reduced cirrhosis by about 10-20 percent

Social host liability for minors and underage drunk-driving accidents

Social host laws for minors aim to reduce teenage alcohol consumption by imposing liability on adults who host parties. Parents cite safety reasons as part of their motivation for hosting parties, preferring their teens and their teens' friends to drink in a supervised and safe locale. Both sides predict an effect of social host liability for minors on alcohol-related traffic accident rates for under-aged drinkers; the effects, however, work in opposite directions. This paper finds that, among 18-20 year olds, social host liability for minors reduced the drunk-driving fatality rate by 9%. I find no effect on sober traffic fatalities. Survey data on drinking and drunk driving suggest the declines resulted mostly from reductions in drunk driving and not reductions in drinking.Drunk driving Social host Alcohol Traffic fatalities