1,418 research outputs found
The Chinese zombie firm: dilemma and resolution
The problems of over-capacity of zombie firms in China have
attracted much attention. However, little is known theoretically,
and even less empirically, about the boundaries and causes of
zombie enterprises. This article extends a model to identify the
characteristics of zombie firms in consideration of supply-side
structural reform in China. We focus on the cause of zombie firms
under the background of the ‘de-capacity’ strategy in China.
Using a sample of Chinese listed companies over the period
2006–2018, we find that the proportion of zombie firms in the
manufacturing industry declined significantly due to expansionary
fiscal policy in 2011. Moreover, the structure of ownership, operational
capabilities, and debt-paying ability co-varies positively,
with state-owned enterprises being most prone to becoming
zombie firms. The results allow us to construct various insights
into how to govern the zombie firm. These results offer a frame
for dealing with zombie firms. Our results are also robust in the
sensitivity test of changing the measurement of zombie firms
Readiness of Congregate Nutrition Sites to Deliver Nutrition Education to Older Adults
Title III of the Older Americans Act requires congregate nutrition sites (CNSs) to provide nutrition education. In 2015, we assessed 19 CNSs in Appalachian South Carolina for nutrition education readiness. Nutrition education readiness and general education readiness were both low. Overall, the CNSs were not ready to deliver education interventions due to lack of training/education, funds, drivers, and communication technologies. Addressing these problems could improve the likelihood that education would be effective. The readiness concepts described here can be used by Extension educators to determine whether delivery sites are ready to effectively provide education programs
Cooking Healthy, Eating Smart: A Strategically Timed Formative Evaluation of a Community-Based Nutrition and Food Safety Program for Rural Older Adults
The use of focus groups to formatively evaluate community-based curricula after development and before pilot testing is not highlighted in the literature. In the study discussed in this article, research with four focus groups, composed of 46 women aged 65 years and older and belonging to eight South Carolina Family and Community Leaders clubs, was conducted to evaluate the Cooking Healthy, Eating Smart (CHES) curriculum. The CHES curriculum was tailored based on suggestions from the older adults. Extension professionals can better prepare a curriculum for pilot testing in the community by conducting a formative evaluation using focus groups with community members at this particular stage of development
Interactive influence of self and other language behaviors: Evidence from switching between bilingual production and comprehension
The neural mechanisms underlying one's own language production and the comprehension of language produced by other speakers in daily communication remain elusive. Here, we assessed how self-language production and other-language comprehension interact within a language switching context using event-related functional Magnetic Resonance Imaging (er-fMRI) in 32 unbalanced Chinese-English bilinguals. We assessed within-modality language interference during language production and comprehension as well as cross-modality interference when switching from production to comprehension and vice versa. Results revealed that the overall effect of production (across switch and repeat trials) was larger in the cross-modality than within-modality condition in a series of attentional control areas, namely the left dorsolateral prefrontal cortex, anterior cingulate cortex and left precuneus. Furthermore, the left precuneus was recruited more strongly in switch trials compared to repeat trials (i.e., switching costs) in within-production conditions but not in the cross-modality condition. These findings suggest that switching from production to comprehension recruits cognitive control areas to successfully implement switches between modalities. However, cross-language interference (in the form of language switching costs) mainly stems from the self-language production system
The study of broomrape diversity in different sunflower cultivating countries based on morphological arameters of parasite seeds
The root holoparasite Orobanche cumana Wallr. produces a very high number of extremely small seeds, which remain viable in the soil for decades and could be easily disseminated through the use of machinery or contaminated seeds. Due this fact and considering the global scale of sunflower seeds exchange, the control of parasite is extremely difficult. Currently broomrape is present in the majority of sunflower cultivation countries and spreads very quickly to new areas. In this context, it is of interest to analyze and highlight distinctive morphological features of O. cumana seeds collected from different European and Asian countries, such as the Republic of Moldova, Romania, Bulgaria, Ukraine, Serbia, Spain, Turkey and China. The morphometric analysis (seed length, width and length/width ratio) of broomrape samples did not show significant differences in their size. O. cumana seeds ranged between 0.316-0.393 mm x 0.148-
0.176 mm, with a L/W ratio of 2.022-2,596. A moderate positive correlation (r=0.485) between length and width of broomrape seeds has been revealed. The mean value of L/W ratio in all investigated populations (38) was around 2.3, being in agreement with the results obtained by other authors and showing that O. cumana has preferentially elongated shape of seeds comparative to other broomrape species. Comparing to other studies, the mean value of L/W ratio was higher than 2.0 (2.18) even in Chinese populations. The coefficients of variation indicated low values, especially in the case of seed length (6.73-19.56%), which suggests a moderate level of intrapopulational variability, all studied populations being relative homogenous. The analysis of Euclidean distance showed small distances (0.001-0.577) between broomrape populations, the most distant being those collected from Seville (Spain), Tulcea (Romania), Xin Jiang (China),
ORSR11 (Serbia), Popeasca and Sarata Mereseni (Republic of Moldova) and Edirne, Kesar (Turkey) in different combinations
Modeling the effect of reduced traffic due to COVID-19 measures on air quality using a chemical transport model : Impacts on the Po Valley and the Swiss Plateau regions
Publisher Copyright: © 2021 The Author(s).The spread of COVID-19 has posed serious challenges for the global communities. To reduce the circulation of the infection, governmental bodies have imposed different lockdown measures at various levels of complexity and duration. As a result, a substantial reduction in mobility might have important, yet unknown, implications for air quality. In this study, we applied the Comprehensive Air quality Model with eXtensions (CAMx) to investigate potential changes in air quality and its chemical composition over northern Italy and Switzerland during periods when lockdown measures were enforced. Our results indicated that lockdown measures reduced nitrogen dioxide (NO2) air concentrations by up to 46% and 25% in the Po Valley and Swiss Plateau regions, respectively, whereas fine particulate matter (PM2.5) air concentrations were reduced only by up to 10% and 6%. This highlights the importance of other emission categories other than traffic for the total PM2.5 levels. The analysis of the PM2.5 components indicated that elemental carbon (EC) and particulate nitrate (NO3 -) were the species most affected by the lockdown measures, whereas a mild increase in the secondary organic aerosol (SOA) concentrations occurred in the Po Valley, and specifically over the metropolitan area of Milan. Our results indicated that an increase in the oxidation capacity of the atmosphere, i.e. in the cOH and cNO3 radicals, was mainly responsible for the mild increase in SOA concentrations.Peer reviewe
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Multi-parametric and multi-regional histogram analysis of MRI: modality integration reveals imaging phenotypes of glioblastoma
Introduction Glioblastoma is characterized by its remarkable heterogeneity and dismal prognosis. Histogram analysis of quantitative magnetic resonance imaging (MRI) is an important in vivo method to study intratumoral heterogeneity. With large amounts of histogram features generated, integrating these modalities effectively for clinical decision remains a challenge. Methods A total of 80 patients with supratentorial primary glioblastoma were recruited. All patients received surgery and standard regimen of temozolomide chemoradiotherapy. Diagnosis was confirmed by pathology. Anatomical T2-weighted, T1-weighted post-contrast and FLAIR images, as well as dynamic susceptibility contrast (DSC), diffusion tensor imaging (DTI) and chemical shift imaging were acquired preoperatively using a 3T MRI scanner. DTI-p, DTI-q, relative cerebral blood volume (rCBV), mean transit time (MTT) and relative cerebral blood flow (rCBF) maps were generated. Contrast-enhancing (CE) and non-enhancing (NE) regions of interest were manually delineated. Voxel intensity histograms were constructed from the CE and NE regions independently. Patient clustering was performed by the Multi-View Biological Data Analysis (MVDA) approach. Kaplan-Meier and Cox proportional hazards regression analyses were performed to evaluate the relevance of the patient clustering to survival. The histogram features selected from MVDA approach were evaluated using receiver operator characteristics (ROC) curve analysis. The metabolic signatures of the patient clusters were analyzed by multivoxel MR spectroscopy (MRS). Results The MVDA approach yielded two final patient clusters, consisting of 53 and 27 patients respectively. The two patient subgroups showed significance for overall survival (p = 0.007, HR = 0.32) and progression-free survival (p Discussion This study demonstrated that integrating multi-parametric and multi-regional MRI histogram features may help to stratify patients. The histogram features selected from the proposed approach may be used as potential imaging markers in personalized treatment strategy and response determination.The research was supported by the National Institute for Health
Research (NIHR) Brain Injury MedTech Cooperative based at Cambridge
University Hospitals NHS Foundation Trust and University of
Cambridge. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR, or the Department of Health and
Social Care (SJP, project reference NIHR/CS/009/011); CRUK core grant
C14303/A17197 and A19274 (FM lab); Cambridge Trust and China
Scholarship Council (CL & SW); the Chang Gung Medical Foundation
and Chang Gung Memorial Hospital, Keelung, Taiwan (JLY); the
Commonwealth Scholarship Commission and Cambridge
Commonwealth Trust (NRB); CRUK & EPSRC Cancer Imaging
Centre in Cambridge & Manchester (FM & TT, grant C197/A16465);
and NIHR Cambridge Biomedical Research Centre (TM & SJP)
Multi-parametric and multi-regional histogram analysis of MRI: modality integration reveals imaging phenotypes of glioblastoma
Introduction Glioblastoma is characterized by its remarkable heterogeneity and dismal prognosis. Histogram analysis of quantitative magnetic resonance imaging (MRI) is an important in vivo method to study intratumoral heterogeneity. With large amounts of histogram features generated, integrating these modalities effectively for clinical decision remains a challenge. Methods A total of 80 patients with supratentorial primary glioblastoma were recruited. All patients received surgery and standard regimen of temozolomide chemoradiotherapy. Diagnosis was confirmed by pathology. Anatomical T2-weighted, T1-weighted post-contrast and FLAIR images, as well as dynamic susceptibility contrast (DSC), diffusion tensor imaging (DTI) and chemical shift imaging were acquired preoperatively using a 3T MRI scanner. DTI-p, DTI-q, relative cerebral blood volume (rCBV), mean transit time (MTT) and relative cerebral blood flow (rCBF) maps were generated. Contrast-enhancing (CE) and non-enhancing (NE) regions of interest were manually delineated. Voxel intensity histograms were constructed from the CE and NE regions independently. Patient clustering was performed by the Multi-View Biological Data Analysis (MVDA) approach. Kaplan-Meier and Cox proportional hazards regression analyses were performed to evaluate the relevance of the patient clustering to survival. The histogram features selected from MVDA approach were evaluated using receiver operator characteristics (ROC) curve analysis. The metabolic signatures of the patient clusters were analyzed by multivoxel MR spectroscopy (MRS). Results The MVDA approach yielded two final patient clusters, consisting of 53 and 27 patients respectively. The two patient subgroups showed significance for overall survival (p = 0.007, HR = 0.32) and progression-free survival (p Discussion This study demonstrated that integrating multi-parametric and multi-regional MRI histogram features may help to stratify patients. The histogram features selected from the proposed approach may be used as potential imaging markers in personalized treatment strategy and response determination.The research was supported by the National Institute for Health
Research (NIHR) Brain Injury MedTech Cooperative based at Cambridge
University Hospitals NHS Foundation Trust and University of
Cambridge. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR, or the Department of Health and
Social Care (SJP, project reference NIHR/CS/009/011); CRUK core grant
C14303/A17197 and A19274 (FM lab); Cambridge Trust and China
Scholarship Council (CL & SW); the Chang Gung Medical Foundation
and Chang Gung Memorial Hospital, Keelung, Taiwan (JLY); the
Commonwealth Scholarship Commission and Cambridge
Commonwealth Trust (NRB); CRUK & EPSRC Cancer Imaging
Centre in Cambridge & Manchester (FM & TT, grant C197/A16465);
and NIHR Cambridge Biomedical Research Centre (TM & SJP)
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