Infections of the upper respiratory tract and counting of leukocytes in volleyball athletes

Submaximal and regular exercise tends to improve the immune response. On the other hand, athletes have a higher incidence of infection of the upper respiratory tract (URTI). The objective of the present study was to correlate the total episodes of URTI with the relative count of circulating neutrophils and lymphocytes in volleyball female athletes, aged 18.92±0.76 years (n=12), within the periods of training. The blood was collected at the end of the periods: Pre-competitive (M1), Competitive-I (M2) and Competitive-II (M3) and the URTI weekly. The athletes participated of 30 weeks of training and competitions. The Pearson correlation coefficient was used, p≤0.05. The results showed moderate to high correlations with 0.8 (p=0.001) and -0.76 (p=0.004) in M1; 0.68 (p=0.014) and -0.59 (p=0.042) in M2; followed by no significant correlations of 0.35 and -0.62 in M3, respectively for neutrophils and lymphocytes when coupled with URTI. The increased number of neutrophils and decreased number of lymphocytes were correlated to URTI and may be useful tools during long time training periods to prevent overload induced immunesuppression

Effect of oat bran on time to exhaustion, glycogen content and serum cytokine profile following exhaustive exercise

The aim of this study was to evaluate the effect of oat bran supplementation on time to exhaustion, glycogen stores and cytokines in rats submitted to training. The animals were divided into 3 groups: sedentary control group (C), an exercise group that received a control chow (EX) and an exercise group that received a chow supplemented with oat bran (EX-O). Exercised groups were submitted to an eight weeks swimming training protocol. In the last training session, the animals performed exercise to exhaustion, (e.g. incapable to continue the exercise). After the euthanasia of the animals, blood, muscle and hepatic tissue were collected. Plasma cytokines and corticosterone were evaluated. Glycogen concentrations was measured in the soleus and gastrocnemius muscles, and liver. Glycogen synthetase-α gene expression was evaluated in the soleus muscle. Statistical analysis was performed using a factorial ANOVA. Time to exhaustion of the EX-O group was 20% higher (515 ± 3 minutes) when compared with EX group (425 ± 3 minutes) (p = 0.034). For hepatic glycogen, the EX-O group had a 67% higher concentrations when compared with EX (p = 0.022). In the soleus muscle, EX-O group presented a 59.4% higher glycogen concentrations when compared with EX group (p = 0.021). TNF-α was decreased, IL-6, IL-10 and corticosterone increased after exercise, and EX-O presented lower levels of IL-6, IL-10 and corticosterone levels in comparison with EX group. It was concluded that the chow rich in oat bran increase muscle and hepatic glycogen concentrations. The higher glycogen storage may improve endurance performance during training and competitions, and a lower post-exercise inflammatory response can accelerate recovery

Influência do exercício físico agudo realizado até a exaustão sobre o número de leucócitos, linfócitos e citocinas circulantes

O objetivo deste estudo foi verificar os efeitos do exercício agudo sobre o número de leucócitos totais, linfócitos e citocinas circulantes. Foram utilizados ratos Wistar, + 2 meses, divididos em 3 grupos (n=6, por grupo): 1) controle sedentário, (C) 2) exercitado em intensidade leve até a exaustão (sem sobrecarga adicional), (EXL) e 3) exercitado em intensidade moderada até a exaustão (sobrecarga de 5% do peso corporal acoplado na região dorsal), (EXM). Foram analisados os leucócitos, linfócitos circulantes e dos linfonodos mesentéricos e concentração de citocinas. Aplicou-se o teste estatístico ANOVA two way, seguido de Post Hoc Tukey, com p?0.05. Foi observado aumento nos leucócitos e linfócitos circulantes para os grupos EXL e EXM comparados ao controle; redução nos linfócitos mesentéricos no EXL em relação ao controle. Foi observado redução no TNF-? no grupo EXM e aumento na IL-6 circulante no EXL quando comparados ao controle. Concluiu-se que, o exercício realizado até a exaustão pode promover leucocitose e linfocitose. O exercício realizado por 10 horas em média (EXL) induz a redução nos linfócitos teciduais, podendo contribuir para a linfocitose nesta mesma situação. O exercício de 10 horas em média eleva a IL-6 e o exercício realizado até a exaustão com sobrecarga reduz o TNF-?

Effects Of Concurrent Training On Interleukin-6, Tumour Necrosis Factor-alpha And C-reactive Protein In Middle-aged Men.

The purpose of this study was to evaluate the effects of moderate- to high-intensity resistance and concurrent training on inflammatory biomarkers and functional capacity in sedentary middle-aged healthy men. Participants were selected on a random basis for resistance training (n = 12), concurrent training (n = 11) and a control group (n = 13). They performed three weekly sessions for 16 weeks (resistance training: 10 exercises with 3 × 8-10 repetition maximum; concurrent training: 6 exercises with 3 × 8-10 repetition maximum, followed by 30 minutes of walking or running at 55-85% [Vdot]O(2peak)). Maximal strength was tested in bench press and leg press. The peak oxygen uptake ([Vdot]O(2peak)) was measured by an incremental exercise test. Tumour necrosis factor-α, interleukin-6 and C-reactive protein were determined. The upper- and lower-body maximal strength increase for both resistance (+42.52%; +20.9%, respectively) and concurrent training (+28.35%; +21.5%, respectively) groups (P = 0.0001).[Vdot]O(2peak) increased in concurrent training when comparing pre- and post-training (P = 0.0001; +15.6%). No differences were found in tumour necrosis factor-α and interleukin-6 for both groups after the exercise. C-reactive protein increased in resistance training (P = 0.004). These findings demonstrated that 16 weeks of moderate- to high-intensity training could improve functional capacity, but did not decrease inflammatory biomarkers in middle-aged men.291573-8