ANTIOVULATORY AND ESTROGENIC ACTIVITY OF LEAVES OF DATURA STRAMONIUM LINN. IN FEMALE ALBINO RATS

The effect of petroleum ether (60-8

Effect of Prenatal Dietary Pattern on Maternal Anemia and Low Birth Weight in Rural Areas of Kanpur

Background: In India, the dietary pattern of women from low socioeconomic status are almost same during pre-pregnant, pregnant and lactating periods. Additional foods are required to improve weight gain in pregnancy and birth weight of infants. Aim & Objective: To identify the impact of prenatal dietary pattern on maternal anemia and low birth weight in rural areas of Kanpur Nagar. Methods: This study was a cross sectional study conducted amongst mothers who recently delivered (RDW) in rural blocks of District Kanpur Nagar. Data was collected by interviewing study subjects using a semi-structured interview schedule after applying multistage random sampling technique. Results: Out of 102 women studied, 39.2% women had consumed >90 IFA tablets, 49.1% of mothers had practiced MMF and 47.1% of women practiced MDD during their prenatal period and 40.1% babies of current pregnancy were born as LBW. IFA consumption during pregnancy was significantly associated with maternal anemia. MMF during pregnancy was significantly associated with LBW. Conclusions: In our study it was found that IFA consumption, MMF and MDD during antenatal is a key preventive measure to reduce anemia status in pregnant females and birth weight of baby during prenatal period

6-Oxo-3-phenyl-5,6-dihydropyridazine-1(4H)-carbohydrazide

We report herein the synthesis of 6-oxo-3-phenyl-5,6-dihydropyridazine-1(4H)-carbohydrazide from β-benzoylpropionic acid and carbohydrazide by refluxing in absolute ethanol in presence of sodium acetate. The structure of the newly synthesized compound was established on the basis of IR, 1H-NMR, 13C-NMR and mass spectral data

Eslicarbazepine acetate: A therapeutic agent of paramount importance in acute anticonvulsant therapy

Eslicarbazepine acetate (ESL) is a new, once daily, orally administered, third generation antiepileptic drug which is indicated in the treatment of partial-onset seizures. ESL is known to exert it’s anticonvulsant effect by blocking the voltage-gated sodium channels. Several clinical trials and pharmacological studies have revealed that seizure control was better with ESL monotherapy (1 200 or 1 600 mg once daily) following a switch from other antiepileptic drugs in comparison with pseudo-placebo patients. The studies have indicated the ESL to be well tolerated and produced only mild to moderate emergent adverse events with the therapy. Being a dibenzazepine family member, structure and chemistry of ESL resembles more or less to carbamazepine and oxcarbazepine. ESL differs structurally from carbamazepine and oxcarbazepine at the 10, 11 position of dibenazepine nucleus. This molecular variation results in differences in metabolism and thus helps to prevent the formation of toxic epoxide metabolites. ESL following oral administration is rapidly metabolised to active metabolite namely S-licarbazepine which is responsible for its pharmacological activity. ESL exhibits acceptable pharmacokinetic profile and shows insignificant drug-drug interactions. In phase III clinical program, ESL was found to be efficacious and well tolerated in adult patients with partial onset seizures previously not controlled with treatment with one or two other antiepileptic drugs

EFFECT OF BEHAVIOUR CHANGE COMMUNICATION ON BREASTFEEDING PRACTICES IN PERIURBAN AREA OF ALIGARH

Objectives: 1.To assess the behavior of pregnant women regarding breastfeeding practices. 2. Assessing impact of Behavior Change Communication Package among pregnant women regarding breastfeeding practices. Study design: A community based intervention study Setting: Field practice areas of Urban Health Training Center, Department of Community Medicine, JNMCH, AMU, Aligarh. Participants: 200 pregnant women (100 pregnant women from each intervention and non-intervention group) Sampling: Purposive sampling method. Statistical Analysis: Data analysed with Epi Info version 3.5.1. Percentages, Relative Risk and Chi Square Test used. Results: Due to implementation of BCC Package in intervention, good practices like giving colostrum were increased two times. Initiation of breastfeeding within 1 hour was increased 4.7 times, exclusive breastfeeding was gone up 3.8 times for first seven days of delivery. There was significant difference (P–value <0.05) between the two groups regarding breastfeeding on 7th day of delivery. The differences were significant (P–value-<0.05) on 7th and 28th days of delivery. Conclusion: Good practices of breastfeeding within one hour, using colostrum, exclusive breastfeeding were improved significantly after implementation of behavior change communication package

Open Access Article│www.njcmindia.org pISSN 0976 3325│eISSN 2229 6816

ABSTRACT Background: Child birth is a normal physiological process, which can become pathological due to the adoption of certain practices and consequently affect the health and survival of the newborn. This will require a renewed and intensified scale up of evidencebased interventions and programs focused on preventing deaths of newborn