171 research outputs found
Trends of Macroeconomic Models
This article provides an overview and analysis of the ideas of the leading macroeconomists expressed in the issue “Rebuilding Macroeconomic Theory”, Oxford Review of Economic Policy journal. These ideas were expressed in connection with the discussion of the future of macroeconomic models. The motivation for the discussion lies in the poor performance of macroeconomic models before the global economic crisis of 2007–2008 and in the subsequent period of recovery. The main issue considered by economists is the possible changes in the basic neoKeynesian model and DSGE-models as a whole. It was found that there are three directions for the solution of the issue. First, the rejection of the primary role of DSGE-models in the analysis of modern macroeconomics and the use of other types of models. Secondly, the elimination of defciencies of existing models associated with poor justifcation at the micro level, as well as an unsatisfactory description of fnancial frictions. Thirdly, it is possible not to make any targeted efforts, since the class of DSGE-models is still the most efcient. The paper concludes that the second path of development is more preferable
Efficacy of Esophageal Protector in Treating Gastroesophageal Reflux Disease with Extraesophageal Symptoms: a Multicenter, Open-Label, Observational Study
Aim: to assess effects of esophageal protector Alfasoxx on extraesophageal symptoms in patients with GERD.Materials and methods. A prospective open multicenter post-registration observational study was conducted. The study included 546 patients aged 6 to 85 years (the average age of patients is 42.4 ± 16.9 years) with a verified diagnosis of GERD (endoscopically and/or pH-metrically), the presence of extraesophageal symptoms of the disease (according to the results of an objective examination and consultations of specialists), to whom the attending physician prescribed a course of treatment with a medical device Alfasoxx in accordance with the instructions for medical use. The patients were recruited by 51 researchers in 26 cities of Russia. The study in chronological order consisted of a screening visit and two recorded visits (the observation period within the framework of the use of the Alfasoxx esophagoprotector). The screening visit was conducted on the day of the patient's admission. Visit 1 could be conducted on the same day as the screening visit, whereas visit 2 was conducted 4–5 weeks after visit 1 at the end of the course of treatment.Results. According to the results obtained, at the end of the study, 42.7 % (95 % CI: 38.5–46.9) had complete disappearance of extraesophageal GERD symptoms (questionnaire RSI = 0 points). When comparing the average values of the total RSI score before and after treatment, there was also a statistically significant regression from 13.8 points (95 % CI: 13.2–14.4) at visit 1 to 2.0 points (95 % CI: 1.8–2.2) at visit 2. Thus, the decrease in the total score was significant and exceeded 80 % of the initial value. When analyzing the dynamics of individual indicators of the RSI scale before and after treatment, a significant regression in the severity of all symptoms of the disease was noted. In addition, the results showed that the proportion of patients taking antacid-containing drugs at visit 1 significantly decreased from 58.2 % (95 % CI: 54.0–62.4) to 15.2 % (95 % CI: 12.1–18.3) by visit 2. The average score on the Likert scale of satisfaction with treatment was 4.8 (95 % CI: 4.8–4.9), whereas the convenience of using Alfasoxx is 4.7.Conclusion. This prospective observational multicenter study demonstrated that the addition of Alfasoxx to standard GERD therapy contributes to a significant regression of both esophageal and extraesophageal symptoms, as well as a decrease in the need for antacid medications
Simulation of Light Antinucleus-Nucleus Interactions
Creations of light anti-nuclei (anti-deuterium, anti-tritium, anti-He3 and
anti-He4) are observed by collaborations at the LHC and RHIC accelerators. Some
cosmic ray experiments are aimed to find the anti-nuclei in cosmic rays. To
support the experimental studies of the anti-nuclei a Monte Carlo simulation of
anti-nuclei interactions with matter is implemented in the Geant4 toolkit. The
implementation combines practically all known theoretical approaches to the
problem of antinucleon-nucleon interactions.Comment: 8 pages, 5 figure
A proposed reaction channel for the synthesis of the superheavy nucleus Z = 109
We apply a statistical-evaporation model (HIVAP) to calculate the cross
sections of superheavy elements, mainly about actinide targets and compare with
some available experimental data. A reaction channel Si + Am is
proposed for the synthesis of the element Z = 109 and the cross section is
estimated.Comment: 4 pages, 2 figures, 2 tables; two typos are corrected in Ref. [12]
and [19
Early onset of ground-state deformation in the neutron-deficient polonium isotopes
In-source resonant ionization laser spectroscopy of the even- polonium
isotopes Po has been performed using the
to ( nm) transition in the polonium atom
(Po-I) at the CERN ISOLDE facility. The comparison of the measured isotope
shifts in Po with a previous data set allows to test for the first
time recent large-scale atomic calculations that are essential to extract the
changes in the mean-square charge radius of the atomic nucleus. When going to
lighter masses, a surprisingly large and early departure from sphericity is
observed, which is only partly reproduced by Beyond Mean Field calculations.Comment: As submitted to PR
Study of polonium isotopes ground state properties by simultaneous atomic- and nuclear-spectroscopy
On inconsistency of experimental data on primary nuclei spectra with sea level muon intensity measurements
For the first time a complete set of the most recent direct data on primary
cosmic ray spectra is used as input into calculations of muon flux at sea level
in wide energy range GeV. Computations have been performed
with the CORSIKA/QGSJET and CORSIKA/VENUS codes. The comparison of the obtained
muon intensity with the data of muon experiments shows, that measurements of
primary nuclei spectra conform to sea level muon data only up to several tens
of GeV and result in essential deficit of muons at higher energies. As it
follows from our examination, uncertainties in muon flux measurements and in
the description of nuclear cascades development are not suitable to explain
this contradiction, and the only remaining factor, leading to this situation,
is underestimation of primary light nuclei fluxes. We have considered
systematic effects, that may distort the results of the primary cosmic ray
measurements with the application of the emulsion chambers. We suggest, that
re-examination of these measurements is required with the employment of
different hadronic interaction models. Also, in our point of view, it is
necessary to perform estimates of possible influence of the fact, that sizable
fraction of events, identified as protons, actually are antiprotons. Study of
these cosmic ray component begins to attract much attention, but today nothing
definite is known for the energies GeV. In any case, to realize whether
the mentioned, or some other reasons are the sources of disagreement of the
data on primaries with the data on muons, the indicated effects should be
thoroughly analyzed
Large-Scale Sidereal Anisotropy of Galactic Cosmic-Ray Intensity Observed by the Tibet Air Shower Array
We present the large-scale sidereal anisotropy ofgalactic cosmic-ray
intensity in the multi-TeV region observed with the Tibet-IIIair shower array
during the period from 1999 through 2003. The sidereal daily variation of
cosmic rays observed in this experiment shows an excess of relative intensity
around hours local sidereal time, as well as a deficit around 12
hours local sidereal time. While the amplitude of the excess is not significant
when averaged over all declinations, the excess in individual declinaton bands
becomes larger and clearer as the viewing direction moves toward the south. The
maximum phase of the excess intensity changes from 7 at the northern
hemisphere to 4 hours at the equatorial region. We also show that both
the amplitude and the phase of the first harmonic vector of the daily variation
are remarkably independent of primary energy in the multi-TeV region. This is
the first result determining the energy and declination dependences of the full
24-hour profiles of the sidereal daily variation in the multi-TeV region with a
single air shower experiment.Comment: 13 pages, 3 figures, 1 table. Accepted for publication in ApJ
- …