The Measurement of Medicaid Coverage in the SIPP : Evidence from a Comparison of Matched Records

This paper studies the accuracy of reported Medicaid coverage in the Survey of Income and Program Participation (SIPP) using a unique data set formed by matching SIPP survey responses to administrative records from the State of California. Overall, we estimate that the SIPP underestimates Medicaid coverage in the California population by about 10 percent. The probability that a SIPP respondent who is covered by Medicaid in a given month correctly reports their coverage is around 85 percent. The corresponding probability for low-income children is higher – around 90 percent. Under-reporting by those who are actually in the Medicaid system is partially offset by over-reporting of coverage by people who are not. Some of these false positive responses are attributable to errors and missing data in the administrative system, rather than to problems in the SIPP. Taking account of these errors, the estimated false positive rate for the population as a whole is about 1.5 percent, and 4-5 percent for poor children.

The Measurement of Medicaid Coverage in the SIPP: Evidence from California, 1990-1996

This paper studies the accuracy of reported Medicaid coverage in the Survey of Income and Program Participation (SIPP) using a unique data set formed by matching SIPP survey responses to administrative records from the State of California. Overall, we estimate that the SIPP underestimates Medicaid coverage in the California population by about 10 percent. Among SIPP respondents who can be matched to administrative records, we estimate that the probability someone reports Medicaid coverage in a month when they are actually covered is around 85 percent. The corresponding probability for low-income children is even higher - at least 90 percent. These estimates suggest that the SIPP provides reasonably accurate coverage reports for those who are actually in the Medicaid system. On the other hand, our estimate of the false positive rate (the rate of reported coverage for those who are not covered in the administrative records) is relatively high: 2.5 percent for the sample as a whole, and up to 20 percent for poor children. Some of this is due to errors in the recording of Social Security numbers in the administrative system, rather than to problems in the SIPP.

High speed quantum gates with cavity quantum electrodynamics

Cavity quantum electrodynamic schemes for quantum gates are amongst the earliest quantum computing proposals. Despite continued progress, and the dramatic recent demonstration of photon blockade, there are still issues with optimal coupling and gate operation involving high-quality cavities. Here we show dynamic control techniques that allow scalable cavity-QED based quantum gates, that use the full bandwidth of the cavities. When applied to quantum gates, these techniques allow an order of magnitude increase in operating speed, and two orders of magnitude reduction in cavity Q, over passive cavity-QED architectures. Our methods exploit Stark shift based Q-switching, and are ideally suited to solid-state integrated optical approaches to quantum computing.Comment: 4 pages, 3 figures, minor revision

The Neon Abundance in the Ejecta of QU Vul From Late-Epoch IR Spectra

We present ground-based SpectroCam-10 mid-infrared, MMT optical, and Spitzer Space Telescope IRS mid-infrared spectra taken 7.62, 18.75, and 19.38 years respectively after the outburst of the old classical nova QU Vulpeculae (Nova Vul 1984 #2). The spectra of the ejecta are dominated by forbidden line emission from neon and oxygen. Our analysis shows that neon was, at the first and last epochs respectively, more than 76 and 168 times overabundant by number with respect to hydrogen compared to the solar value. These high lower limits to the neon abundance confirm that QU Vul involved a thermonuclear runaway on an ONeMg white dwarf and approach the yields predicted by models of the nucleosynthesis in such events.Comment: ApJ 2007 accepted, 18 pages, including 5 figures, 1 tabl

Constructive control of quantum systems using factorization of unitary operators

We demonstrate how structured decompositions of unitary operators can be employed to derive control schemes for finite-level quantum systems that require only sequences of simple control pulses such as square wave pulses with finite rise and decay times or Gaussian wavepackets. To illustrate the technique it is applied to find control schemes to achieve population transfers for pure-state systems, complete inversions of the ensemble populations for mixed-state systems, create arbitrary superposition states and optimize the ensemble average of dynamic observables.Comment: 28 pages, IoP LaTeX, principal author has moved to Cambridge University ([email protected]

Landau-Zener Problem for Trilinear Hamiltonians

We consider a nonlinear version of the Landau-Zener problem, focusing on photoassociation of a Bose-Einstein condensate as a specific example. Contrary to the exponential rate dependence obtained for the linear problem, a series expansion technique indicates that, when the resonance is crossed slowly, the probability for failure of adiabaticity is directly proportional to the rate at which the resonance is crossed.Comment: 4.5 pages, 1 figure, transferred to PRA; v2 adds discussion, clarification, and explicit numbers for Na and 87R

A comparative approach to understanding tissue-specific expression of uncoupling protein 1 expression in adipose tissue

Peer reviewedPublisher PD

Crustal and Upper-mantle Structure Beneath Ice-covered Regions in Antarctica from S-wave Receiver Functions and Implications for Heat Flow

S-wave receiver functions (SRFs) are used to investigate crustal and upper-mantle structure beneath several ice-covered areas of Antarctica. Moho S-to-P (Sp) arrivals are observed at ~6–8 s in SRF stacks for stations in the Gamburtsev Mountains (GAM) and Vostok Highlands (VHIG), ~5–6 s for stations in the Transantarctic Mountains (TAM) and the Wilkes Basin (WILK), and ~3–4 s for stations in the West Antarctic Rift System (WARS) and the Marie Byrd Land Dome (MBLD). A grid search is used to model the Moho Sp conversion time with Rayleigh wave phase velocities from 18 to 30 s period to estimate crustal thickness and mean crustal shear wave velocity. The Moho depths obtained are between 43 and 58 km for GAM, 36 and 47 km for VHIG, 39 and 46 km for WILK, 39 and 45 km for TAM, 19 and 29 km for WARS and 20 and 35 km for MBLD. SRF stacks for GAM, VHIG, WILK and TAM show little evidence of Sp arrivals coming from upper-mantle depths. SRF stacks for WARS and MBLD show Sp energy arriving from upper-mantle depths but arrival amplitudes do not rise above bootstrapped uncertainty bounds. The age and thickness of the crust is used as a heat flow proxy through comparison with other similar terrains where heat flow has been measured. Crustal structure in GAM, VHIG and WILK is similar to Precambrian terrains in other continents where heat flow ranges from ~41 to 58 mW m−2, suggesting that heat flow across those areas of East Antarctica is not elevated. For the WARS, we use the Cretaceous Newfoundland–Iberia rifted margins and the Mesozoic-Tertiary North Sea rift as tectonic analogues. The low-to-moderate heat flow reported for the Newfoundland–Iberia margins (40–65 mW m−2) and North Sea rift (60–85 mW m−2) suggest that heat flow across the WARS also may not be elevated. However, the possibility of high heat flow associated with localized Cenozoic extension or Cenozoic-recent magmatic activity in some parts of the WARS cannot be ruled out

Single photon quantum non-demolition in the presence of inhomogeneous broadening

Electromagnetically induced transparency (EIT) has been often proposed for generating nonlinear optical effects at the single photon level; in particular, as a means to effect a quantum non-demolition measurement of a single photon field. Previous treatments have usually considered homogeneously broadened samples, but realisations in any medium will have to contend with inhomogeneous broadening. Here we reappraise an earlier scheme [Munro \textit{et al.} Phys. Rev. A \textbf{71}, 033819 (2005)] with respect to inhomogeneities and show an alternative mode of operation that is preferred in an inhomogeneous environment. We further show the implications of these results on a potential implementation in diamond containing nitrogen-vacancy colour centres. Our modelling shows that single mode waveguide structures of length $200 \mu\mathrm{m}$ in single-crystal diamond containing a dilute ensemble of NV$^-$ of only 200 centres are sufficient for quantum non-demolition measurements using EIT-based weak nonlinear interactions.Comment: 21 pages, 9 figures (some in colour) at low resolution for arXiv purpose

Real-world outcomes of sipuleucel-T treatment in PROCEED, a prospective registry of men with metastatic castration-resistant prostate cancer.

BackgroundThe large registry, PROVENGE Registry for the Observation, Collection, and Evaluation of Experience Data (PROCEED)(NCT01306890), evaluated sipuleucel-T immunotherapy for asymptomatic/minimally symptomatic metastatic castration-resistant prostate cancer (mCRPC).MethodsPROCEED enrolled patients with mCRPC receiving 3 biweekly sipuleucel-T infusions. Assessments included overall survival (OS), serious adverse events (SAEs), cerebrovascular events (CVEs), and anticancer interventions (ACIs). Follow-up was for ≥3 years or until death or study withdrawal.ResultsIn 2011-2017, 1976 patients were followed for 46.6 months (median). The median age was 72 years, and the baseline median prostate-specific antigen level was 15.0 ng/mL; 86.7% were white, and 11.6% were African American. Among the patients, 1902 had 1 or more sipuleucel-T infusions. The median OS was 30.7 months (95% confidence interval [CI], 28.6-32.2 months). Known prognostic factors were independently associated with OS in a multivariable analysis. Among the 1255 patients who died, 964 (76.8%) died of prostate cancer (PC) progression. The median time from the first infusion to PC death was 42.7 months (95% CI, 39.4-46.2 months). The incidence of sipuleucel-T-related SAEs was 3.9%. The incidence of CVEs was 2.8%, and the rate per 100 person-years was 1.2 (95% CI, 0.9-1.6). The CVE incidence among 11,972 patients with mCRPC from the Surveillance, Epidemiology, and End Results-Medicare database was 2.8%; the rate per 100 person-years was 1.5 (95% CI, 1.4-1.7). One or more ACIs (abiraterone, enzalutamide, docetaxel, cabazitaxel, or radium 223) were received by 77.1% of the patients after sipuleucel-T; 32.5% and 17.4% of the patients experienced 1- and 2-year treatment-free intervals, respectively.ConclusionsPROCEED provides contemporary survival data for sipuleucel-T-treated men in a real-world setting of new life-prolonging agents, which will be useful in discussing treatment options with patients and in powering future trials with sipuleucel-T. The safety and tolerability of sipuleucel-T in PROCEED were consistent with previous findings