3,145 research outputs found

    How important are labor markets to the welfare of the poor in Indonesia?

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    A majority of the poor in Indonesia come from agricultural and self-employed households. Moreover, the largest single contribution to poverty reduction between 1990 and 1993 came from within-sector welfare gains to self-employed farm households. Data show that the role of the labor market in reducing poverty has increased since the mid-1980s. Wage labor markets can be expected to play an increasingly important impact on the welfare of Indonesia's poor as the economy continues to undergo structural change, and as the workforce moves out of agriculture into manufacturing and services. Because poverty remains largely an agricultural and self-employed phenomenon, the most direct way to reduce poverty is to focus on improving the operation of product, land, and capital markets. At the same time, labor market policy can play an important role in the Government's poverty reduction efforts by helping to facilitate labor mobility across sectors. But if they reduce labor mobility, labor market policies can be counterproductive to Indonesia's poverty reduction efforts. Recent empirical evidence suggests that increases in the minimum wage may have hurt employment growth, particularly among small firms. As such, using minimum wage policy to ensure high wages to a limited number of workers will almost certainly diminish the poverty reducing potential of the labor markets.Health Economics&Finance,Environmental Economics&Policies,Labor Policies,Services&Transfers to Poor,Poverty Monitoring&Analysis,Rural Poverty Reduction,Environmental Economics&Policies,Poverty Assessment,Health Economics&Finance,Safety Nets and Transfers

    Shocks and coffee : lessons from Nicaragua

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    Using household level panel data from Nicaragua, this paper explores the impact of the recent coffee crisis on rural households engaged in coffee production, and coffee labor work. Taking advantage of the panel structure of the data, a number of findings emerge: a) while overall growth between 1998, and 2001 was widespread in rural Nicaragua, coffee households saw large declines in various socioeconomic outcomes; b) among coffee households, it is small farm households that were affected the most, and not poor labor households as previously expected; c) even though coffee households used various risk management strategies to address the shock, it was pre shock, ex-ante strategies (like income diversification) that were the most effective in allowing coffee households insulate against the shock. By contrast, the coffee households that used ex-post coping instruments, did not manage to mitigate the adverse impact as well, with additional potential long run implications via extensive uses of harmful coping strategies (like increases in child labor); and, d) the coffee shock affected upward mobility, and downward poverty vulnerability of coffee households. Such findings seem to confirm the widespread impact of shocks on overall household behavior, and indicate the importance of incorporating risk management in the policy agenda of poverty reduction.Housing&Human Habitats,Regional Rural Development,Crops&Crop Management Systems,VN-Acb Mis -- IFC-00535908,Environmental Economics&Policies

    Potential implication of Paxillin in cancer establishment within the bone environment

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    Background: Bone metastases are a common feature of advanced prostatic malignancies. They are characterised by a unique prevalence of osteoblastic phenotype and a poor prognosis. Paxillin is a 68-kDa signal transduction adaptor and scaffold protein that contains motifs involved in the mediation of protein–protein interactions. The state of paxillin phosphorylation is central to determining a cell's ability to adhere, detach and migrate and hence has been linked to processes such as wound repair and tumour metastasis. The current study explored the impact of paxillin suppression on prostate and breast cancer cell function and their responsiveness to hepatocyte growth factor (HGF) and bone matrix extract (BME) in order to assess its potential to influence bone colonization and homing. Materials and Methods: Hammerhead ribozyme transgenes were used to knockdown the expression of paxillin in breast and prostate cancer cell lines. The impact on the cell growth, migration, adhesion and invasion was assessed using in vitro functional assays. In order to explore potential mechanisms, focal adhesion kinase (FAK) inhibitor was also used. Results: Knockdown of paxillin expression was observed in all tested cell lines following transfection with the ribozyme transgene. The knockdown of paxillin increased proliferation and invasiveness of LNCaP cells, with no effect on their attachment abilities. The opposite, however, is true for PC-3 cells where, following knockdown, cellular attachment was significantly reduced, while no significant changes in growth and invasiveness were detected. In the MDA-MB-231 breast cancer knockdown model, cells had little difference in proliferative rates and generally increased attachment and reduced invasive abilities. Treatments with HGF and BME had differential effects on targeted cells when compared to controls. Conclusion: These data suggest that paxillin appears to influence major cell functions in a diverse range of prostate and breast cancer models. The responsiveness of cells to environmental factors such as HGF or BME may be influenced by paxillin status, although this seems to be dependent on cell type

    A Microinstrumentation System for Remote Environmental Monitoring

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    This paper reports on a hybrid micro-instrumentation system that includes a embedded micro-controller, transducers for monitoring environmental parameters, interface/readout electronics for linking the controller and the transducers, and custom circuitry for system power management. Sensors for measuring temperature, pressure, humidity, and acceleration are included in the initial system, which operates for more than 180 days and dissipates less than 700 microW from a 6V battery supply. The sensor scan rate is adaptive and can be event triggered. The system communicates internally over a 1 MHz, nine-line intramodule sensor bus and outputs data over a hard-wired serial interface or a 315MHz wireless link. The use of folding platform packaging allows an internal system volume as small as 5 cc

    Flux expulsion with dynamics

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    In the process of flux expulsion, a magnetic field is expelled from a region of closed streamlines on a TR1/3 m time scale, for magnetic Reynolds number Rm ≫ 1 (T being the turnover time of the flow). This classic result applies in the kinematic regime where the flow field is specified independently of the magnetic field. A weak magnetic ‘core’ is left at the centre of a closed region of streamlines, and this decays exponentially on the TR1/2 m time scale. The present paper extends these results to the dynamical regime, where there is competition between the process of flux expulsion and the Lorentz force, which suppresses the differential rotation. This competition is studied using a quasi-linear model in which the flow is constrained to be axisymmetric. The magnetic Prandtl number Rm/Re is taken to be small, Rm large, and a range of initial field strengths b0 is considered. Two scaling laws are proposed and confirmed numerically. For initial magnetic fields below the threshold bcore = O(UR−1/3 m ), flux expulsion operates despite the Lorentz force, cutting through field lines to result in the formation of a central core of magnetic field. Here U is a velocity scale of the flow and magnetic fields are measured in AlfvÂŽen units. For larger initial fields the Lorentz force is dominant and the flow creates AlfvÂŽen waves that propagate away. The second threshold is bdynam = O(UR−3/4 m ), below which the field follows the kinematic evolution and decays rapidly. Between these two thresholds the magnetic field is strong enough to suppress differential rotation leaving a magnetically controlled core spinning in solid body motion, which then decays slowly on a time scale of order TRm

    An assessment of chemical contaminants in the marine sediments of southwest Puerto Rico

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    This report summarizes the results of a characterization of chemical contaminants in the sediments in southwest Puerto Rico. The report is part of a project to integrate various analytical specialties to assess linkages between chemical contaminants and the condition of coral reefs. In this phase of the project, over 120 chemical contaminants were analyzed in sediments collected, including a number of organic (e.g., hydrocarbons), inorganic (e.g., metals), and biological (bacterial) compounds/analytes. The report also provides a preliminary analysis of the association between sediment contaminants and coral species richness. Overall, the levels of chemical contaminants in the study area between Guanica Bay and the town of La Parguera were fairly low. At most of the sites sampled, particularly adjacent to the town of La Parguera, concentrations of organic and inorganic contaminants were below the median values from NOAA’s National Status and Trends Program, which monitors the Nation’s coastal and estuarine waters for chemical contaminants. Elevated levels of a number of contaminant classes were seen at the two sites sampled within Guanica Bay. An initial analysis of modeled PAH (hydrocarbon) data and coral species richness (reef building species) indicated a strong negative correlation between the presence of PAHs in the sediments and coral species richness. Additional work is needed to assess possible reasons for this observed pattern. (PDF contains 126 pages)

    IL-17B Can Impact on Endothelial Cellular Traits Linked to Tumour Angiogenesis

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    IL-17B is a member of the IL-17 cytokine family which have been implicated in inflammatory response and autoimmune diseases such as rheumatoid arthritis. The founding member of this family, IL-17 (or IL-17A), has also been implicated in promoting tumour angiogenesis through the induction of other proangiogenic factors. Here we examine the potential of recombinant human IL-17B to contribute to the angiogenic process. In vitro rhIL-17B was able to inhibit HECV endothelial cell-matrix adhesion and cellular migration and also, at higher concentrations, could substantially reduce tubule formation compared to untreated HECV cells in a Matrigel tubule formation assay. This data suggests that IL-17B may act in an antiangiogenic manner

    Structure and dielectric response in the high TcT_c ferroelectric Bi(Zn,Ti)O3_3-PbTiO3_3 solid solutions

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    Theoretical {\em ab initio} and experimental methods were used to investigate the xxBi(Zn,Ti)O3_3-(1-xx)PbTiO3_3 (BZT-PT) solid solution. We find that hybridization between Zn 4pp and O 2pp orbitals allows the formation of short, covalent Zn-O bonds, enabling favorable coupling between A-site and B-site displacements. This leads to large polarization, strong tetragonality and an elevated ferroelectric to paraelectric phase transition temperature. nhomogeneities in local structure near the 90∘^\circ domain boundaries can be deduced from the asymetric peak broadening in the neutron and x-ray diffraction spectra. These extrinsic effects make the ferroelectric to paraelectric phase transition diffuse in BZT-PT solid solutions

    Targeting the Poor in Rural Java

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    Summaries This article examines the regional and household characteristics of poverty in rural Java to assess the efficacy of targeted anti?poverty programmes. Analysis of household data shows important geographic and spatial features to rural poverty in Java. However, it also highlights the limitations of geographic targeting; 43 per cent of remaining poor in rural Java live in non?poor regions. The article suggests that an effective anti?poverty strategy for rural Java would focus on continued broad?based growth, judicious use of geographic targeting, and special efforts to enhance the poor's access to productive assets, regardless of where they live
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