Body composition in clinical practice

Nutritional status is the results of nutrients intake, absorption and utilization, able to influence physiological and pathological conditions. Nutritional status can be measured for individuals with different techniques, such as CT Body Composition, quantitative Magnetic Resonance Imaging, Ultrasound, Dual-Energy X-Ray Absorptiometry and Bioimpendance. Because obesity is becoming a worldwide epidemic, there is an increasing interest in the study of body composition to monitor conditions and delay in development of obesity-related diseases. The emergence of these evidence demonstrates the need of standard assessment of nutritional status based on body weight changes, playing an important role in several clinical setting, such as in quantitative measurement of tissues and their fluctuations in body composition, in survival rate, in pathologic condition and illnesses. Since body mass index has been shown to be an imprecise measurement of fat-free and fat mass, body cell mass and fluids, providing no information if weight changes, consequently there is the need to find a better way to evaluate body composition, in order to assess fat-free and fat mass with weight gain and loss, and during ageing. Monitoring body composition can be very useful for nutritional and medical interventional. This review is focused on the use of Body Composition in Clinical Practice

Planejamento da atividade leiteira: sugestões para os produtores iniciantes.

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Water activity in lamellar stacks of lipid bilayers: "Hydration forces" revisited

Water activity and its relationship with interactions stabilising lamellar stacks of mixed lipid bilayers in their fluid state are investigated by means of osmotic pressure measurements coupled with small-angle x-ray scattering. The (electrically-neutral) bilayers are composed of a mixture in various proportions of lecithin, a zwitterionic phospholipid, and Simulsol, a non-ionic cosurfactant with an ethoxylated polar head. For highly dehydrated samples the osmotic pressure profile always exhibits the "classical" exponential decay as hydration increases but, depending on Simulsol to lecithin ratio, it becomes either of the "bound" or "unbound" types for more water-swollen systems. A simple thermodynamic model is used for interpreting the results without resorting to the celebrated but elusive "hydration forces"Comment: 24 pages, 12 figures. Accepted for publication in The European Physical Journal

Sludge Treatment and Disposal

"Sludge Treatment and Disposal is the sixth volume in the series Biological Wastewater Treatment. The book covers in a clear and informative way the sludge characteristics, production, treatment (thickening, dewatering, stabilisation, pathogens removal) and disposal (land application for agricultural purposes, sanitary landfills, landfarming and other methods). Environmental and public health issues are also fully described. About the series: The series is based on a highly acclaimed set of best selling textbooks. This international version is comprised by six textbooks giving a state-of-the-art presentation of the science and technology of biological wastewater treatment. Other titles in the series are: Volume 1: Waste Stabilisation Ponds; Volume 2: Basic Principles of Wastewater Treatment; Volume 3: Waste Stabilization Ponds; Volume 4: Anaerobic Reactors; Volume 5: Activated Sludge and Aerobic Biofilm Reactors

A low-energy perspective on the minimal left-right symmetric model

We perform a global analysis of the low-energy phenomenology of the minimal left-right symmetric model (mLRSM) with parity symmetry. We match the mLRSM to the Standard Model Effective Field Theory Lagrangian at the left-right-symmetry breaking scale and perform a comprehensive fit to low-energy data including mesonic, neutron, and nuclear $\beta$-decay processes, $\Delta F=1$ and $\Delta F=2$ CP-even and -odd processes in the bottom and strange sectors, and electric dipole moments (EDMs) of nucleons, nuclei, and atoms. We fit the Cabibbo-Kobayashi-Maskawa and mLRSM parameters simultaneously and determine a lower bound on the mass of the right-handed $W_R$ boson. In models where a Peccei-Quinn mechanism provides a solution to the strong CP problem, we obtain $M_{W_R} \gtrsim 5.5$ TeV at $95\%$ C.L. which can be significantly improved with next-generation EDM experiments. In the $P$-symmetric mLRSM without a Peccei-Quinn mechanism we obtain a more stringent constraint $M_{W_R} \gtrsim 17$ TeV at $95\%$ C.L., which is difficult to improve with low-energy measurements alone. In all cases, the additional scalar fields of the mLRSM are required to be a few times heavier than the right-handed gauge bosons. We consider a recent discrepancy in tests of first-row unitarity of the CKM matrix. We find that, while TeV-scale $W_R$ bosons can alleviate some of the tension found in the $V_{ud,us}$ determinations, a solution to the discrepancy is disfavored when taking into account other low-energy observables within the mLRSM.Comment: 42 pages plus appendices. Published versio

Hepatic Steatosis and Thyroid Function Tests in Overweight and Obese Children

Objectives. Associations between thyroid function and nonalcoholic fatty liver disease (NAFLD) are unknown in childhood. Thus, the aim of the present study was to investigate in 402 consecutive overweight/obese children the association between thyroid function tests and hepatic steatosis as well as metabolic variables. Methods. Hepatic steatosis was diagnosed by ultrasound after exclusion of infectious and metabolic disorders. Fasting serum samples were taken for determination of thyroid function (TSH, FT4, and FT3), along with alanine aminotransferase (ALT), lipid profile, glucose, insulin, and insulin resistance (IR). Results. Eighty-eight children (21.9%) had TSH above the normal range (>4.0 mIU/L). FT3 and FT4 were within the reference intervals in all subjects. Elevated TSH was associated with increased odds of having hepatic steatosis (OR 2.10 (95% CI, 1.22–3.60)), hepatic steatosis with elevated ALT (2.42 (95% CI, 1.29–4.51)), hypertriglyceridemia, elevated total cholesterol, and IR as well as metabolic syndrome (considered as a single clinical entity), after adjustment for age, gender, pubertal status, and body mass index-SD score (or waist circumference). Conclusions. In overweight/obese children, elevated TSH concentration is a significant predictor of hepatic steatosis and lipid and glucose dysmetabolism, independently of the degree of total and visceral obesity

Epidemiological surveillance of human enteric viruses by monitoring of different environmental matrices.

In the aim of studying possible relations between viruses detected in clinical specimens and the ones found in different environmental matrices, in the period May 2004 to April 2005, the collection of faecal samples from gastroenteritis cases and the monthly monitoring of raw and treated wastewater, river water, seawater and mussels were carried out. The viruses considered for environmental monitoring were adenovirus, rotavirus, enterovirus, norovirus, hepatitis A virus (HAV) and Torque teno virus (TTV): they were searched for with PCR and RT-PCR and confirmed by gene sequencing. Faecal coliforms and somatic coliphages' counts were also determined. The surveillance of case detected 45 positive faecal samples out of 255 (17.6%) while 35 of 56 environmental samples (62.5%) resulted positive for at least one of the considered viruses. The detection of the same viral strain in the faeces of gastroenteritis cases and in water was possible for adenovirus and rotavirus, which were also predominant in environmental matrices; thus they could be considered as a reference for risk assessment

Acrylamide levels in cooked rice, tomato sauces and some fast food on the Italian market

This study reports the results of evaluation of acrylamide levels in some foods that are common on the Italian market. Three foods commonly found in the national diet (rice, tomato sauce and fast food), were examined with the gas chromatograph (GC)/mass spectrometer (MS) analytical method. Results show that rice differs from risotto with respect to acrylamide levels: values of less than 50 \u3bcg/kg, for boiled rice, increase to 113 \u3bcg/kg when various ingredients are added to produce risotto. Similar results were found for tomato sauce on the Italian market: acrylamide values were less than 50 \u3bcg/kg for simple tomato sauce, to 124 \u3bcg/kg when other ingredients such as olives and capers were added. Fast foods (e.g., fried potatoes) contained the highest observed acrylamide levels, probably from cooking methods and acrylamide-rich precursors. For two fried potatoes of the same type, very differentiated values resulted (136 and 294 \u3bcg/kg)