Breuil-Mézard conjectures for central division algebras

We give a parametrization of the inertial classes of smooth representations of inner forms of GL(n) over a p-adic field, based on type-theoretic invariants. Then we give a complete description of the behaviour of this parametrization under the Jacquet–Langlands correspondence, proving a conjecture of Broussous, Sécherre and Stevens on preservation of endo-classes. As an application of this result, we construct a Jacquet–Langlands transfer of types and Serre weights for central division algebras, and use it to deduce a form of the Breuil–Mézard conjecture, for discrete series Galois deformation rings and types of central division algebras, from the conjectural statement for GL(n).Open Acces

Localization of smooth p-power torsion representations of GL_2(Q_p)

We show that the category of smooth representations of GL_2(Q_p) on p-power torsion modules localizes over a certain projective scheme, and give some applications.Comment: 64 pages; fixing a couple of typo

Adsorption and recovery of phosphate from aqueous solution by the construction and demolition wastes sludge and its potential use as phosphate-based fertiliser

This study aimed to investigate phosphate removal from aqueous effluents by an inorganic sludge from the inert part of construction and demolition wastes (CSW) as adsorbent. It is also discussed the application of the loaded P adsorbent as potential fertiliser. The CSW was also thermally treated at 800¿°C for 2¿h (CSW-T), and its influence in the P removal was also investigated. The characterisation techniques highlighted low porosity on CSW and CSW-T adsorbents and that they are mainly formed by oxides which could enhance the P uptake and recovery. In pH experiments, P adsorption increased as initial pH increased, at pH higher than 7.8 the P removal sharply increased due to the formation of calcium phosphate precipitate. The mechanism of the P adsorption onto CSW indicated that the process was mainly controlled by chemical bonding or chemisorption. The results showed that CSW-T was more effective for P removal in comparison to CSW based on the Liu isotherm, the maximum sorption capacity attained was 24.04 (CSW) and 57.64¿mg¿g-1 (CSW-T). Based on the Avrami’s kinetic models, the time for attaining 95% of saturation was 212.6 (CSW), and 136.6¿min (CSW-T). CSW and CSW-T showed the highest phosphate-removal performance among many adsorbents found in the literature; therefore, this kind of waste can be used widely as an inexpensive phosphate-recovery adsorbent. Besides, the P loaded adsorbents could be used as potential fertilisers which could be an interesting and efficient way of reuse for this waste.Peer ReviewedPostprint (published version

Lymphocyte-to-monocyte ratio and clinical outcomes in Cholangiocarcinoma: A systematic review and meta-analysis

Antecedentes y objetivos: La relación de linfocitos a monocitos (LMR) ha demostrado una asociación con los resultados de supervivencia en varias enfermedades oncológicas. Este estudio tuvo como objetivo evaluar la asociación entre LMR y los resultados clínicos para pacientes con colangiocarcinoma. Material y métodos: Se realizó una revisión sistemática y un metaanálisis para evaluar la asociación entre los valores de LMR y la supervivencia general (SG), la supervivencia libre de enfermedad (DFS), la supervivencia libre de recurrencia (RFS) y el tiempo hasta la recurrencia (TTR) en pacientes con colangiocarcinoma. Utilizamos el cociente de riesgos (HR) y el intervalo de confianza (IC) del 95 % como medida del efecto para el metaanálisis del modelo de efectos aleatorios. Se utilizó la escala de Newcastle-Ottawa para la evaluación de la calidad. La prueba de Egger y el gráfico en embudo se desarrollaron para abordar el sesgo de publicación. Resultados: En este estudio se incluyeron un total de 19 estudios (n = 3860). El metaanálisis mostró que los pacientes con colangiocarcinoma con valores bajos de LMR se asociaron con peor SG (HR: 0,82; IC 95 %: 0,71–0,96; I2 = 86 %) y peor TTR (HR: 0,71; IC 95 %: 0,58- 0,86; I2 = 0%). También se evaluaron DFS y RFS; sin embargo, no mostraron asociaciones estadísticamente significativas.Background and aims: Lymphocyte-to-Monocyte Ratio (LMR) has shown an association with survival outcomes in several oncological diseases. This study aimed to evaluate the association between LMR and survival outcomes for cholangiocarcinoma patients. Materials and Methods: A systematic review and meta-analysis was performed to assess the association between LMR and overall survival (OS), disease-free survival (DFS), recurrence-free survival (RFS) and time to recurrence (TTR) in cholangiocarcinoma patients. We used hazard ratios (HRs) and their 95% confidence intervals (CIs) as a measure of effect for the random effect model meta-analysis. The Newcastle-Ottawa Scale was used for quality assessment. The Egger test and funnel plot were developed for approaching publication bias. Results: A total of 19 studies were included in this study (n=3860). The meta-analysis showed that cholangiocarcinoma patients with low values of LMR were associated with worse OS (HR: 0.82; 95% CI: 0.71-0.96; I2=86%) and TTR (HR: 0.71; 95% CI: 0.58-0.86; I2=0%). DFS and RFS also were evaluated; however, they did not show statistically significant associations. Conclusion: Low LMR values were associated with worse OS and TTR.Tesi

Nanoparticles from evaporite materials in Colombian coal mine drainages

Ultrathin and nanometric materials (minerals and amorphous phases) are detected in transitory deposits of potential hazardous elements (PHEs), especially in acidic coal mine drainages. The main goal of this work was to evaluate the occurrence of PHEs in nanoparticles (NPs) in evaporative structures in coal mining areas with high concentrations of PHEs. The precipitates were sampled in several coal mining areas in Colombia, with the purpose of evaluating the geochemical and environmental structures. In the present work, to better diagnose areas affected by coal mining, an innovative analytical procedure is proposed to define the association between PHEs in mine drainage sediments. The procedure includes the analytical study with X-Ray Diffraction (XRD) and advanced electron microscopy, before and after a series of sequential extractions to separate amorphous, magnetic, and crystalline compounds. Of the three main types of precipitates identified, the yellowish precipitates had the highest amounts of PHEs while the white precipitates had only small amounts of PHEs and the greenish precipitates contained TiO2 nanoparticles. The results from this study will be usable for more than fifty countries that have coal mine drainages

The Active Component of Aspirin, Salicylic Acid, Promotes Staphylococcus aureus Biofilm Formation in a PIA-dependent Manner

Aspirin has provided clear benefits to human health. But salicylic acid (SAL) -the main aspirin biometabolite- exerts several effects on eukaryote and prokaryote cells. SAL can affect, for instance, the expression of Staphyiococcus aureus virulence factors. SAL can also form complexes with iron cations and it has been shown that different iron chelating molecules diminished the formation of S. aureus biofilm. The aim of this study was to elucidate whether the iron content limitation caused by SAL can modify the S. aureus metabolism and/or metabolic regulators thus changing the expression of the main polysaccharides involved in biofilm formation. The exposure of biofilm to 2mM SAL induced a 27% reduction in the intracellular free Fe2+ concentration compared with the controls. In addition, SAL depleted 23% of the available free Fe2+ cation in culture media. These moderate iron-limited conditions promoted an intensificaron of biofilms formed by strain Newman and by S. aureus clinical isolates related to the USA300 and USA100 clones. The slight decrease in iron bioavailability generated by SAL was enough to induce the increase of PIA expression in biofilms formed by methicillin-resistant as well as methicillin-sensitive S. aureus strains. S. aureus did not produce capsular polysaccharide (CP) when it was forming biofilms under any of the experimental conditions tested. Furthermore, SAL diminished aconitase activity and stimulated the lactic fermentation pathway in bacteria forming biofilms. The polysaccharide composition of S. aureus biofilms was examined and FTIR spectroscopic analysis revealed a clear impact of SAL in a codY-dependent manner. Moreover, SAL negatively affected codY transcription in mature biofilms thus relieving the CodY repression of the ica operon. Treatment of mice with SAL induced a significant increase of S aureus colonization. It is suggested that the elevated PIA expression induced by SAL might be responsible for the high nasal colonization observed in mice. SAL-induced biofilms may contribute to S. aureus infection persistence in vegetarian individuals as well as in patients that frequently consume aspirin.Facultad de Ciencias Médica

Crescimento de feijão-caupi cultivado em Plintossolo Pétrico Concrecionário

Os Plintossolos com a presença de cascalho de petroplintita nos horizontes superficiais do solo apresentam características indesejadas do ponto de vista agronômico. Logo, o feijão-caupi, Vigna unguiculata, é considerado uma planta rústica a qual consegue se desenvolver em condições adversas no contexto nutricional e hídrico do solo. Diante disso, o objetivo do trabalho foi de avaliar o desenvolvimento do feijão-caupi cultivado em solo com e sem concreções de petroplintita. Dois tratamentos, solo com concreções de petroplintita e solo sem concreções foram montados. Trocas gasosas foram determinadas e a parte aérea e radicular foram separadas, secas e pesadas. Os resultados foram comparados por meio de teste de Wilcoxon independente e Kruskal-Wallis a 5% de probabilidade. Transpiração, condutância estomática e temperatura foliar, mostraram diferença estatística aos 45 dias após a emergência (DAE) com menores valores no feijão cultivado em solo sem petroplintita. O feijão cultivado em solo com petroplintita apresentou maior massa seca radicular e menor relação parte aérea radicular. Os resultados demonstram que cascalhos de petroplintita interferiram nas trocas gasosas e sistema radicular do feijão-caupi, mas que a espécie se mostrou rústica, capaz de se desenvolver em um ambiente radicular adverso