4,412 research outputs found

    "Патриотические граффити" к проблеме использования диалогической и монологической форм коммуникации в рамках государственной пропаганды в работе с молодежью (социально-философский аспект)

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    Научно-квалификационная работа посвящена исследованию социально-культурного явления, возникшего в конце 2000-х годов и получившего называние "патриотические граффити". Данное явление исследуется в аспекте деятельности российского государства по пропаганде патриотизма.Scientific qualification work is devoted to the study of social and cultural phenomena that arose in the late 2000s and was called "Patriotic graffiti". This phenomenon is studied in the aspect of the Russian state's activities topropagandize patriotism

    Dispersion relations for the time-fractional Cattaneo-Maxwell heat equation

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    In this paper, after a brief review of the general theory of dispersive waves in dissipative media, we present a complete discussion of the dispersion relations for both the ordinary and the time-fractional Cattaneo-Maxwell heat equations. Consequently, we provide a complete characterization of the group and phase velocities for these two cases, together with some non-trivial remarks on the nature of wave dispersion in fractional models.Comment: 18 pages, 7 figure

    Application of a photo-identification based assessment model to southern right whales in South African waters

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    The three-mature-stages (receptive, calving and resting) model of Cooke et al. (2003) is applied to photo-identification data available from 1979 to 2010 for southern right whales in South African waters. The 2010 number of females having reached the age at first parturition is estimated to be 1 205, the total population (including males and calves) 4 725, and the annual population growth rate 6.8%. The probability (average 11%) that a resting mature whale rests for a further year appears to vary annually, whereas the probability (7%) that a receptive whale rest (or aborts) rather than calves the next year appears to be constant. Information from resightings of grey blazed calves as adults with calves allows estimation of first year survival rate of 0.914 (compared to a subsequent annual rate of 0.987, and an age at 50% maturity of 6.4 years. However this suggests also that 27% (s.e. 6%) of grey blazed calves lose their marking before becoming adults. In contrast, the relative proportions of grey blazed animals amongst calves and amongst calving adults suggest rather a value of 10% (s.e. 8%). If the proportion losing markings is in fact 10%, first year survival rates estimate drops to 0.837 and the population growth rate to 6.4% pa

    Prognostic value of clinical and MRI features in the screening of lipomatous lesions

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    BACKGROUND AND OBJECTIVES: Differentiation of lipomatous tumors mostly requires diagnostic biopsy but is essential to decide for the most adequate therapy. This study aims to investigate the prognostic value of available clinical and radiological features with regard to malignancy of the lesion, recurrence and survival. METHODS: In this retrospective cohort study, 104 patients with a biopsy-proven lipomatous tumor between 2010 and 2015 and a minimum clinical follow-up of two years were enrolled. Next to clinical features (age, gender, location of the lesion, histopathologic diagnosis, stage of disease, time to recurrence and death), MRI parameters were recorded retrospectively and blinded to the histological diagnosis. RESULTS: Malignant lipomatous tumors were associated with location in the lower extremities and MRI features like thick septation (>2 mm), presence of a non-adipose mass, foci of high T2/STIR signal and contrast agent enhancement. A non-adipose mass was a predictor for recurrence and inferior overall survival, while lesions with high T2/STIR signal showed higher risk of recurrence only. In combination, clinical and radiological features (lower extremities, septation > 2 mm, existence of non-adipose mass, contrast enhancement, and foci of high T2/STIR signal) predicted a malignant lipomatous tumor with an accuracy of 0.941 (95% CI of 0.899-0.983; 87% sensitivity, 86% specificity). CONCLUSION: Localization and characteristic MR features predict malignancy in most lipomatous lesions. Non-adipose masses are a poor prognostic factor, being associated with tumor recurrence and disease-related death

    Estimating the abundance of common dolphins on the southern coast of South Africa

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    Sightings made on an aerial survey in December 1982 and on a ship-based survey in January/February 1983 have been used to assess the size of the population of common dolphins (Delphinus capensis) occurring over the continental shelf south of South Africa. Thirteen sightings (12 primary) were made in 2,445.7 n. miles flown on the aerial survey and 10 sightings (6 primary) in 1,772.2 n. miles steamed on the ship-based survey. Sightings and effort in both surveys have been stratified by water depth (0-100 m, 100- 200 m) and geographical region (west coast, south coast). Because of difficulties in accurately estimating the size of schools in this highly gregarious species, numbers of individuals were counted in composite aerial photographs taken of the school. Radial distance and angle estimates to sightings from the ship were smeared to allow for estimation errors. Assuming g(0) = 1.0, both data sets resulted in roughly similar estimates of the number of schools (52-58 for aerial, 40-59 for ship-based across a range of sensitivity tests), but mean school size estimates differed significantly (454 SE 90 for aerial, 159 SE 27 for ship-based). As the aerial estimates were based on counts of animals in composite vertical photographs, they are considered more reliable than the ship-based estimates that were made from a lower vantage point and at a greater angle. Given the small number of primary sightings on each survey, it was considered preferable to produce a combined estimate using school density estimates from both surveys weighted by their inverse variances but applying the mean school size from the aircraft. The resultant population estimate of 49 schools (CV = 0.29) and 22200 individuals (CV = 0.35) is discussed in relation to known or estimated incidental mortalities in South African waters

    Neural Network Parametrization of Deep-Inelastic Structure Functions

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    We construct a parametrization of deep-inelastic structure functions which retains information on experimental errors and correlations, and which does not introduce any theoretical bias while interpolating between existing data points. We generate a Monte Carlo sample of pseudo-data configurations and we train an ensemble of neural networks on them. This effectively provides us with a probability measure in the space of structure functions, within the whole kinematic region where data are available. This measure can then be used to determine the value of the structure function, its error, point-to-point correlations and generally the value and uncertainty of any function of the structure function itself. We apply this technique to the determination of the structure function F_2 of the proton and deuteron, and a precision determination of the isotriplet combination F_2[p-d]. We discuss in detail these results, check their stability and accuracy, and make them available in various formats for applications.Comment: Latex, 43 pages, 22 figures. (v2) Final version, published in JHEP; Sect.5.2 and Fig.9 improved, a few typos corrected and other minor improvements. (v3) Some inconsequential typos in Tab.1 and Tab 5 corrected. Neural parametrization available at http://sophia.ecm.ub.es/f2neura

    Preliminary results for a photo-identification-based assessment of southern right whales in South African waters

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    This working paper presents preliminary results of a photo-id based assessment of southern right whales in South African waters using the three-mature-stages (receptive, calving, resting) model of Cooke et al. (2003). The application of the approach is near-identical to that of Cooke et al. (2003), except that here the starting population is not assumed to reflect a steady age-structure corresponding to the Leslie matrix model describing the population dynamics. The photo-id data for grey-blazed female calves, which are identifiable when giving birth themselves, are used to link the dynamics of the mature females with the output of their reproduction by allowing for estimation of parameters for first-year mortality and the maturity ogive

    Evolution of Blood-Brain Barrier Permeability in Subacute Ischemic Stroke and Associations With Serum Biomarkers and Functional Outcome

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    Background and Purpose: In the setting of acute ischemic stroke, increased blood-brain barrier permeability (BBBP) as a sign of injury is believed to be associated with increased risk of poor outcome. Pre-clinical studies show that selected serum biomarkers including C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF alpha), matrix metallopeptidases (MMP), and vascular endothelial growth factors (VEGFs) may play a role in BBBP post-stroke. In the subacute phase of stroke, increased BBBP may also be caused by regenerative mechanisms such as vascular remodeling and therefore may improve functional recovery. Our aim was to investigate the evolution of BBBP in ischemic stroke using contrast-enhanced (CE) magnetic resonance imaging (MRI) and to analyze potential associations with blood-derived biomarkers as well as functional recovery in subacute ischemic stroke patients. Methods: This is an exploratory analysis of subacute ischemic stroke patients enrolled in the BAPTISe study nested within the randomized controlled PHYS-STROKE trial (interventions: 4 weeks of aerobic fitness training vs. relaxation). Patients with at least one CE-MRI before (v1) or after (v2) the intervention were eligible for this analysis. The prevalence of increased BBBP was visually assessed on T1-weighted MR-images based on extent of contrast-agent enhancement within the ischemic lesion. The intensity of increased BBBP was assessed semi-quantitatively by normalizing the mean voxel intensity within the region of interest (ROI) to the contralateral hemisphere ("normalized CE-ROI"). Selected serum biomarkers (high-sensitive CRP, IL-6, TNF-alpha, MMP-9, and VEGF) at v1 (before intervention) were analyzed as continuous and dichotomized variables defined by laboratory cut-off levels. Functional outcome was assessed at 6 months after stroke using the modified Rankin Scale (mRS). Results: Ninety-three patients with a median baseline NIHSS of 9 [IQR 6-12] were included into the analysis. The median time to v1 MRI was 30 days [IQR 18-37], and the median lesion volume on v1 MRI was 4 ml [IQR 1.2-23.4]. Seventy patients (80%) had increased BBBP visible on v1 MRI. After the trial intervention, increased BBBP was still detectable in 52 patients (74%) on v2 MRI. The median time to v2 MRI was 56 days [IQR 46-67]. The presence of increased BBBP on v1 MRI was associated with larger lesion volumes and more severe strokes. Aerobic fitness training did not influence the increase of BBBP evaluated at v2. In linear mixed models, the time from stroke onset to MRI was inversely associated with normalized CE-ROI (coefficient -0.002, Standard Error 0.007, p < 0.01). Selected serum biomarkers were not associated with the presence or evolution of increased BBBP. Multivariable regression analysis did not identify the occurrence or evolution of increased BBBP as an independent predictor of favorable functional outcome post-stroke. Conclusion: In patients with moderate-to-severe subacute stroke, three out of four patients demonstrated increased BBB permeability, which decreased over time. The presence of increased BBBP was associated with larger lesion volumes and more severe strokes. We could not detect an association between selected serum biomarkers of inflammation and an increased BBBP in this cohort. No clear association with favorable functional outcome was observed
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