Trajectories in a space with a spherically symmetric dislocation

We consider a new type of defect in the scope of linear elasticity theory, using geometrical methods. This defect is produced by a spherically symmetric dislocation, or ball dislocation. We derive the induced metric as well as the affine connections and curvature tensors. Since the induced metric is discontinuous, one can expect ambiguity coming from these quantities, due to products between delta functions or its derivatives, plaguing a description of ball dislocations based on the Geometric Theory of Defects. However, exactly as in the previous case of cylindric defect, one can obtain some well-defined physical predictions of the induced geometry. In particular, we explore some properties of test particle trajectories around the defect and show that these trajectories are curved but can not be circular orbits.Comment: 11 pages, 3 figure

Mechanisms of subcutaneous adipose tissue formation in experimental lymphedema model

no abstrac

Mechanisms of subcutaneous adipose tissue formation in experimental lymphedema model

no abstrac

O "Paradoxo" e a "Galinha": o Controle Organizacional e as Comunidades de Prática

Uma comunidade de prática (CdP) pode ser entendida como qualquer grupo cujas pessoas, possuindo prática e referência epistemológica em comum, reúnem-se regularmente para refletir sobre essa prática, aprendendo coletivamente a entendê-la e, principalmente, a fazê-la melhor. Mas o que acontece com uma CdP quando ela é “descoberta”, incentivada e gerida por uma organização? De que forma a cultura e o controle organizacionais tomam parte nessa relação? Os estudos organizacionais sobre CdP’s têm tido, predominantemente, uma abordagem funcionalista. Partindo de outra perspectiva, este texto pretende fazer uma análise teórico-conceitual sobre as CdP’s e sua relação com as organizações da produção e do trabalho, particularmente no que se referem a aspectos de controle organizacional presentes em tal relação, e tomando como base obras e estudos organizacionais recentes sobre o assunto. Conclui-se que a gestão de CdP’s nas organizações é uma impossibilidade conceitual, resultando num paradoxo: ao gerir-se uma CdP, ela deixa de existir

Investigating dimensionality and measurement bias of DSM-5 alcohol use disorder in a representative sample of the largest metropolitan area in South America

Background: Given the recent launch of a new diagnostic classification (DSM-5) for alcohol use disorders (AUD), we aimed to investigate its dimensionality and possible measurement bias in a non-U.S. sample. Methods: The current analyses were restricted to 948 subjects who endorsed drinking at least one drink per week in the past year from a sample of 5037 individuals. Data came from São Paulo Megacity Project (which is part of World Mental Health Surveys) collected between 2005 and 2007. First, exploratory factor analysis (EFA) was carried out to test for the best dimensional structure for DSM-5-AUD criteria. Then, item response theory (IRT) was used to investigate the severity and discrimination properties of each criterion of DSM-5-AUD. Finally, differential criterion functioning (DCF) were investigated by socio-demographics (income, gender, age, employment status, marital status and education). All analyses were performed in Mplus software taking into account complex survey design features. Results: The best EFA model was a one-dimensional model. IRT results showed that the criteria “Time Spent” and “Given Up” have the highest discrimination and severity properties, while the criterion “Larger/Longer” had the lowest value of severity, but an average value of discrimination. Only female gender had DCF both at criterion- and factor-level, rendering measurement bias. Conclusion: This study reinforces the existence of a DSM-5-AUD continuum in the largest metropolitan area of South America, including subgroups that had previously higher rates of alcohol use (lower educational/income levels). Lower DSM-5-AUD scores were found in women

Pacientes hipertensos muestran una mayor respuesta de la frecuencia cardíaca durante el ejercicio progre-sivo en relación con pares adultos normotensos: Proyecto Vascu-Health

Existe información limitada respecto a la respuesta de la frecuencia cardiaca (FC) a partir de fórmulas predictivas y prueba de ejercicio real entre adultos con hipertensión arterial (HTA) y normotensos, así como sobre las similitudes o diferencias vasculares entre muestras de diferente control de la presión arterial. El objetivo de este estudio fue describir y comparar la frecuencia cardiaca durante el ejercicio entre adultos con HTN y normotensos, así como describir parámetros de función endotelial y vasculares. Se realizó un estudio clínico descriptivo con 64 adultos (hombres y mujeres) que fueron divididos en tres grupos: hipertensión arterial (HTN n=26), presión arterial elevada (Ele n=16), o normotensos control (CG n=22). Los participantes se sometieron a una prueba de ejercicio, en la que se midió la FC (variable principal) y parámetros vasculares secundarios (clasificación percentil de la velocidad de la onda del pulso (%ILEPWVba), grosor máximo de la íntima-media carotídea (cIMTmax) y edad arterial entre otras. En la etapa 2 del test (50-100 vatios), el grupo HTN mostró una FC significativamente mayor vs. el grupo GC (+14 latidos/min), y vs. el grupo Ele (+15 latidos/min), ambos p<0,05; y en la etapa 5 (125-250 vatios) vs. el grupo GC (+22 latidos/min; p<0,05). El grupo HTN mostró una clasificación mayor de rigidez arterial %ILEPWVba, y de edad arterial que el grupo NT. En conclusión, los sujetos con HTA presentan una mayor respuesta de la FC durante el ejercicio que los normotensos. Sin embargo, todos los grupos mostraron una mayor HRpredicted en relación con la HRpeak real. Estos resultados se muestran con una clasificación en percentiles superiores de rigidez arterial y una mayor estimación de la edad arterial con relación a adultos normotensos.There is limited information regarding heart rate (HR) response from predictive formulae and actual exercise tests between arterial hypertension (HTN) and normotensive adults, as well as about vascular similarities or differences between samples of different blood pressure control. This study aimed 1) to describe and compare the HR during exercise between HTN and normotensive adults and 2) to describe the endothelial function and related vascular parameters in both groups. A descriptive clinical study was conducted with 64 adults (men and women) who were divided into three groups: arterial hypertension (HTN n=26), elevated blood pressure (Ele n=16), or normotensive control (CG n=22). The participants underwent a incremental cycling exercise test of 5 stages, where HR (primary outcome) was measured, and secondary vascular outcomes (percentile classification of the pulse wave velocity (%ILEPWVba), maximum carotid intima-media thickness (cIMTmax), and arterial age among others were measured. In stage 2 of the test (50-100 watts), the HTN group showed significantly higher HR vs. CG (+14 beats/min; p<0.05) and vs. Ele group (+15 beats/min; p<0.05), and in stage 5 (125-250 watts), HTN group showed vs. CG (+22 beats/min; p<0.05). HTN group showed a higher arterial stiffness by %ILEPWVba classification and arterial age estimation than the CG group. In conclusion, HTN patients reported a higher HR response only in two out of five stages of the Astrand cycling exercise test than normotensive peers. Moreover, all groups showed a higher HRpredicted than real HRpeak obtained from the exercise test. These results are displayed with more altered vascular parameters in the HTN group.This research was funded by Direccion General de In-vestigación, Vicerrectoria de Investigación y Doctorado, Concurso de Ciencias Biomédicas y Clínicas, Universidad Andres Bello 2022 Código N° DI-01-CBC/22”. Also, the main author (C.A.) was funded by the Exercise and Reha-bilitation Sciences Institute, School of Physical Therapy, Faculty of Rehabilitation Sciences, Universidad Andres Bello, Santiago, 7591538, Chile

DSM-5 latent classes of alcohol users in a population-based sample: Results from the São Paulo Megacity Mental Health Survey, Brazil

Background: We aimed to identify different categorical phenotypes based upon the DSM-V criteria of alcohol use disorders (AUD) among alcohol users who had at least one drink per week in the past year (n = 948). Methods: Data are from the São Paulo Megacity Mental Health Survey collected in 2005–2007, as part of the World Mental Health Survey Initiative. A latent class analysis of the 11 DSM-5-AUD criteria was performed using Mplus, taking into account complex survey design features. Weighted logistic regression models were used to examine demographic correlates of the DSM-5-AUD latent classes. Results: The best latent-class model was a three-class model. We found a “non-symptomatic class” (69.7%), a “use in larger amounts class” (23.2%), defined by high probability (>70%) of the “use in larger amounts” criterion only, and a “high-moderate symptomatic class” (7.1%), defined by high-moderate probability of all the 11 AUD criteria. Compared to those in the non-symptomatic class, individuals in the “high-moderate symptomatic class” were more likely to have been married, have lower educational attainment and to be unemployed or in non-regular/informal employment. Those on the “use in larger amounts class” were more likely to have been married or never married. Conclusion: The two symptomatic classes clearly represented the dimensionality of the new proposed AUD criteria, and could be more specifically targeted by different prevention or treatment strategies. DSM-5-AUD has the advantage of shedding light on risky drinkers included in the “use in larger amounts class”, allowing for preventive interventions, which will reach a large number of individuals

Produção de mudas.

Para implantação de um pomar de maracujazeiro é importante a obtenção/produção de mudas de qualidade e vigorosas. Apesar de propagados por métodos assexuais, como enxertia, estaquia e micropropagação, os pomares comerciais de maracujazeiro-amarelo ou do tipo azedo são formados, principalmente, por propagação sexuada, a partir de sementes, sejam comerciais ou obtidas a partir de seleção em pomares, conforme critérios apresentados neste tópico. O produtor deve sempre optar por mudas de qualidade e sadias, provenientes de cultivares indicadas pelos órgãos de pesquisa. No geral, a muda de qualquer espécie frutífera, incluindo o maracujazeiro, pode representar uma expressiva porcentagem do sucesso do pomar, o que significa dizer que o produtor consciente da importância da muda de qualidade terá maior êxito em seu plantio. Entretanto, a opção por mudas de qualidade não dispensa a utilização mais racional e técnica do manejo do pomar. Portanto, mudas de qualidade, associadas à realização das práticas culturais indispensáveis ao cultivo do maracujazeiro, podem levar os pomares a atingirem significativa produção.bitstream/item/223854/1/27147.pdfPublicação eletrônica