Comparing Observed Stellar Kinematics and Surface Densities in a Low-latitude Bulge Field to Galactic Population Synthesis Models

We present an analysis of Galactic bulge stars from Hubble Space Telescope Wide Field Camera 3 observations of the Stanek window (l, b = [0.25,-2.15]) from two epochs approximately two years apart. This data set is adjacent to the provisional Wide-field Infrared Survey Telescope (WFIRST) microlensing field. Proper motions are measured for approximately 115,000 stars down to 28th mag in V band and 25th mag in I band, with accuracies of 0.5 mas yr-1 (20 km s-1) at I ≈ 21. A cut on the longitudinal proper motion μ l allows us to separate disk and bulge populations and produce bulge-only star counts that are corrected for photometric completeness and efficiency of the proper-motion cut. The kinematic dispersions and surface density in the field are compared to the nearby SWEEPS sight line, finding a marginally larger-than-expected gradient in stellar density. The observed bulge star counts and kinematics are further compared to the Besançon, Galaxia, and GalMod Galactic population synthesis models. We find that most of the models underpredict low-mass bulge stars by ∼33% below the main-sequence turnoff, and upwards of ∼70% at redder J and H wavebands. While considering inaccuracies in the Galactic models, we give implications for the exoplanet yield from the WFIRST microlensing mission

Quantum rotor theory of spinor condensates in tight traps

In this work, we theoretically construct exact mappings of many-particle bosonic systems onto quantum rotor models. In particular, we analyze the rotor representation of spinor Bose-Einstein condensates. In a previous work it was shown that there is an exact mapping of a spin-one condensate of fixed particle number with quadratic Zeeman interaction onto a quantum rotor model. Since the rotor model has an unbounded spectrum from above, it has many more eigenstates than the original bosonic model. Here we show that for each subset of states with fixed spin F_z, the physical rotor eigenstates are always those with lowest energy. We classify three distinct physical limits of the rotor model: the Rabi, Josephson, and Fock regimes. The last regime corresponds to a fragmented condensate and is thus not captured by the Bogoliubov theory. We next consider the semiclassical limit of the rotor problem and make connections with the quantum wave functions through use of the Husimi distribution function. Finally, we describe how to extend the analysis to higher-spin systems and derive a rotor model for the spin-two condensate. Theoretical details of the rotor mapping are also provided here.Comment: 10 pages, 2 figure

Differential gene expression in Varroa jacobsoni mites following a host shift to European honey bees (Apis mellifera)

Background: Varroa mites are widely considered the biggest honey bee health problem worldwide. Until recently, Varroa jacobsoni has been found to live and reproduce only in Asian honey bee (Apis cerana) colonies, while V. destructor successfully reproduces in both A. cerana and A. mellifera colonies. However, we have identified an island population of V. jacobsoni that is highly destructive to A. mellifera, the primary species used for pollination and honey production. The ability of these populations of mites to cross the host species boundary potentially represents an enormous threat to apiculture, and is presumably due to genetic variation that exists among populations of V. jacobsoni that influences gene expression and reproductive status. In this work, we investigate differences in gene expression between populations of V. jacobsoni reproducing on A. cerana and those either reproducing or not capable of reproducing on A. mellifera, in order to gain insight into differences that allow V. jacobsoni to overcome its normal species tropism. Results: We sequenced and assembled a de novo transcriptome of V. jacobsoni. We also performed a differential gene expression analysis contrasting biological replicates of V. jacobsoni populations that differ in their ability to reproduce on A. mellifera. Using the edgeR, EBSeq and DESeq R packages for differential gene expression analysis, we found 287 differentially expressed genes (FDR ≤ 0.05), of which 91% were up regulated in mites reproducing on A. mellifera. In addition, mites found reproducing on A. mellifera showed substantially more variation in expression among replicates. We searched for orthologous genes in public databases and were able to associate 100 of these 287 differentially expressed genes with a functional description. Conclusions: There is differential gene expression between the two mite groups, with more variation in gene expression among mites that were able to reproduce on A. mellifera. A small set of genes showed reduced expression in mites on the A. mellifera host, including putative transcription factors and digestive tract developmental genes. The vast majority of differentially expressed genes were up-regulated in this host. This gene set showed enrichment for genes associated with mitochondrial respiratory function and apoptosis, suggesting that mites on this host may be experiencing higher stress, and may be less optimally adapted to parasitize it. Some genes involved in reproduction and oogenesis were also overexpressed, which should be further studied in regards to this host shift. © 2016 The Author(s)

Hubble Tarantula Treasury Project. IV. The extinction law

We report on the study of interstellar extinction across the Tarantula nebula (30 Doradus), in the Large Magellanic Cloud, using observations from the Hubble Tarantula Treasury Project in the 0.3 - 1.6 micron range. The considerable and patchy extinction inside the nebula causes about 3500 red clump stars to be scattered along the reddening vector in the colour-magnitude diagrams, thereby allowing an accurate determination of the reddening slope in all bands. The measured slope of the reddening vector is remarkably steeper in all bands than in the the Galactic diffuse interstellar medium. At optical wavelengths, the larger ratio of total-to-selective extinction, namely Rv = 4.5 +/- 0.2, implies the presence of a grey component in the extinction law, due to a larger fraction of large grains. The extra large grains are most likely ices from supernova ejecta and will significantly alter the extinction properties of the region until they sublimate in 50 - 100 Myr. We discuss the implications of this extinction law for the Tarantula nebula and in general for regions of massive star formation in galaxies. Our results suggest that fluxes of strongly star forming regions are likely to be underestimated by a factor of about 2 in the optical.Comment: 15 pages, 10 figures, accepted for publication in MNRAS; Updated references, corrected typos in Table

LEGUS Discovery of a Light Echo Around Supernova 2012aw

We have discovered a luminous light echo around the normal Type II-Plateau Supernova (SN) 2012aw in Messier 95 (M95; NGC 3351), detected in images obtained approximately two years after explosion with the Wide Field Channel 3 on-board the Hubble Space Telescope (HST) by the Legacy ExtraGalactic Ultraviolet Survey (LEGUS). The multi-band observations span from the near-ultraviolet through the optical (F275W, F336W, F438W, F555W, and F814W). The apparent brightness of the echo at the time was ~21--22 mag in all of these bands. The echo appears circular, although less obviously as a ring, with an inhomogeneous surface brightness, in particular, a prominent enhanced brightness to the southeast. The SN itself was still detectable, particularly in the redder bands. We are able to model the light echo as the time-integrated SN light scattered off of diffuse interstellar dust in the SN environment. We have assumed that this dust is analogous to that in the Milky Way with R_V=3.1. The SN light curves that we consider also include models of the unobserved early burst of light from the SN shock breakout. Our analysis of the echo suggests that the distance from the SN to the scattering dust elements along the echo is ~45 pc. The implied visual extinction for the echo-producing dust is consistent with estimates made previously from the SN itself. Finally, our estimate of the SN brightness in F814W is fainter than that measured for the red supergiant star at the precise SN location in pre-SN images, possibly indicating that the star has vanished and confirming it as the likely SN progenitor.Comment: 10 pages, 9 figures, to appear in the Astrophysical Journa

Like trainer, like bot? Inheritance of bias in algorithmic content moderation

The internet has become a central medium through which `networked publics' express their opinions and engage in debate. Offensive comments and personal attacks can inhibit participation in these spaces. Automated content moderation aims to overcome this problem using machine learning classifiers trained on large corpora of texts manually annotated for offence. While such systems could help encourage more civil debate, they must navigate inherently normatively contestable boundaries, and are subject to the idiosyncratic norms of the human raters who provide the training data. An important objective for platforms implementing such measures might be to ensure that they are not unduly biased towards or against particular norms of offence. This paper provides some exploratory methods by which the normative biases of algorithmic content moderation systems can be measured, by way of a case study using an existing dataset of comments labelled for offence. We train classifiers on comments labelled by different demographic subsets (men and women) to understand how differences in conceptions of offence between these groups might affect the performance of the resulting models on various test sets. We conclude by discussing some of the ethical choices facing the implementers of algorithmic moderation systems, given various desired levels of diversity of viewpoints amongst discussion participants.Comment: 12 pages, 3 figures, 9th International Conference on Social Informatics (SocInfo 2017), Oxford, UK, 13--15 September 2017 (forthcoming in Springer Lecture Notes in Computer Science

Connectivity between white shark populations off Central California, USA and Guadalupe Island, Mexico

Marine animals often move beyond national borders and exclusive economic zones resulting in a need for trans-boundary management spanning multiple national jurisdictions. Highly migratory fish vulnerable to over-exploitation require protections at international level, as exploitation practices can be disparate between adjacent countries and marine jurisdictions. In this study we collaboratively conducted an analysis of white shark connectivity between two main aggregation regions with independent population assessment and legal protection programs; one off central California, USA and one off Guadalupe Island, Mexico. We acoustically tagged 326 sub-adult and adult white sharks in central California (n=210) and in Guadalupe Island (n=116) with acoustic transmitters between 2008-2019. Of the 326 tagged white sharks, 30 (9.20%) individuals were detected at both regions during the study period. We used a Bayesian implementation of logistic regression with a binomial distribution to estimate the effect of sex, maturity, and tag location to the response variable of probability of moving from one region to the other. While nearly one in ten individuals in our sample were detected in both regions over the study period, the annual rate of trans-regional movement was low (probability of movement = 0.015 yr-1, 95% credible interval = 0.002, 0.061). Sub-adults were more likely than adults to move between regions and sharks were more likely to move from Guadalupe Island to central California, however, sex, and year were not important factors influencing movement. This first estimation of demographic-specific trans-regional movement connecting US and Mexico aggregations with high seasonal site fidelity represents an important step to future international management and assessment of the northeastern Pacific white shark population as a whole

Pilots for Space Tourism

This article sheds light on the key player needed for any space tourism adventure: the pilot who flies the spacecraft. The paper addresses the potential benefits of including a pilot at the controls when designing a space tourism spacecraft. It examines the basic qualifications and advanced skills required of space tourism pilots and discusses key training requirements for selected pilots and space pilots’ pay and benefits. In addition, the research concludes that, just as the pioneers of passenger transport in aviation entertained and captured the interest of their passengers, the space pilot should have the skills of a tour guide

OR.107. TIM-1 Plays a Crucial Role in the Expansion of Autopathogneic T-Cells and Regulation of Autoimmunity [abstract only]

T-cell immunoglobulin and mucin (TIM) family Members are differentially expressed on Th1 and Th2 cells. Polymorphisms of TIM-1 have been associated with susceptibility to asthma; however, its role in regulating autoimmunity has not been studied. Here, we have used an agonistic antiTIM-1 antibody (Ab, Clone 3B3) which has previously been shown to costimulate T-cell activation and expansion, to analyze the role of TIM-1 in the development and regulation of experimental autoimmune encephalomyelitis (EAE). Treatment with 3B3 dramatically enhances the severity of EAE as well as the frequency of encephalitogenic CD4+ T-cells and the production of IFN-g and IL-17 by these cells. Furthermore, administration of 3B3 breaks self-tolerance and induces EAE in the disease resistant B10.S strain. We have utilized another anti-TIM-1 Ab (RMT1-10) that does not costimulate T-cell activation in vitro. In contrast to 3B3, treatment with RMT1-10 inhibits the development of EAE and reduces the frequency of encephalitogenic CD4+ T-cells with a commensurate decrease in the production of IFN-g and IL-17. Treatment with RMT1-10 causes CD4+ T-cells to produce more IL-4 and IL-10. We provide evidence that both 3B3 and RMT1-10 bind to the same epitope in the Ig domain of TIM-1, but the binding affinity of 3B3 is much higher than that of RMT1-10. These data suggest that TIM-1 engagement with the agonistic Ab, along with TcR ligation, costimulates T-cell expansion with pro-inflammatory IFN-g and IL-17 production resulting in the breakdown of self-tolerance and development of autoimmunity, whereas blocking anti-TIM-1 Ab causes a decrease in the autopathogenic Th1/ThIL-17 responses. This study demonstrates that TIM-1 is a key cell surface molecule that regulates effector T-cell response and depending on hopw the molecule is engaged, autoimmune responses can be either enhanced or inhibited in vivo