Anthocyanin Profile and Antioxidant Property of Anti-asthma Flowers of Cordyline terminalis (L.) Kunth (Agavaceae)

Cordyline terminalis flower is traditionally used to treat asthma and the purple color of the flower is suggestive of anthocyanins. The purpose of this study was to characterize and determine the antioxidant property of anthocyanins from C. terminalis purple flowers. Five anthocyanins, cyanidin 3,5-di-O-β-glucopyranoside (2.6 ± 0.2 mg/g fr. wt) (1), peonidin 3,5-di-O-β-glucopyranoside (2.8 ± 0.3 mg/g fr. wt) (2), cyanidin 3-O-β-(6″-O-E-p-caffeoylglucopyranoside)-5-O-β-glucopyranoside (3.2 ± 0.2 mg/g fr. wt) (3), cyanidin 3-O-β-(6″-O-E-p-coumaroylglucopyranoside)-5-O-β-glucopyranoside (6.2 ± 0.4 mg/g fr. wt) (4), and peonidin 3-O-β-(6″-O-E-p-coumaroylglucopyranoside)-5-O-β-glucopyranoside (9.8 ± 0.2 mg/g fr. wt) (5), were isolated from the flowers of C. terminalis by a combination of chromatographic techniques. Their structures were established by UV-visible, NMR, and ESI-MS. The extract exhibited appreciable antioxidant activity (IC50 ± SD = 13.1 ± 0.8 μg/mL) against quercetin (IC50 ± SD = 4.5 ± 0.4 μg/mL) compared to the individual anthocyanins (IC50 ± SD = 13.8 ± 0.5 to 16.4 ± 0.7 μg/mL) when measured using the 2,2-diphenyl-1-picryl-hydrazyl method. Cordyline terminalis flowers extract may be justified for use and standardization as herbal remedy for asthma.publishedVersio

Patient safety culture improvements depend on basic healthcare education:a longitudinal simulation-based intervention study at two Danish hospitals

BACKGROUND: A growing body of evidence supports the existence of an association between patient safety culture (PSC) and patient outcomes. PSC refers to shared perceptions and attitudes towards norms, policies and procedures related to patient safety. Existing literature shows that PSC varies among health professionals depending on their specific profession and specialty. However, these studies did not investigate whether PSC can be improved. This study investigates whether length of education is associated with improvements in PCS following a simulation intervention. METHODS: From April 2017 to November 2018, a cross-sectional intervention study was conducted at two regional hospitals in Denmark. Two groups with altogether 1230 health professionals were invited to participate. One group included nurses, midwives and radiographers; the other group included doctors. A train-the-trainer intervention approach was applied consisting of a 4-day simulation instructor course that emphasised team training, communication and leadership. Fifty-three healthcare professionals were trained as instructors. After the course, instructors performed in situ simulation in their own hospital environment. OUTCOMES: The Safety Attitude Questionnaire (SAQ), which has 6 dimensions and 32 items, was used to collect main outcome variables. All employees from both groups were surveyed before the intervention and again four and nine months after the intervention. RESULTS: Mean baseline scores were higher among doctors than among nurses, midwives and radiographers for all SAQ dimensions. At the second follow-up, four of six dimensions improved significantly (p ≤ 0.05) among nurses, midwives and radiographers, whereas no dimensions improved significantly among doctors. CONCLUSION: Over time, nurses, midwives and radiographers improved more in PSC attitudes than doctors did

Classification and evaluation of the residential sector for the implementation of massive energy retrofit strategies

Se plantea evaluar el parque edilicio residencial existente de la Patagonia Argentina, utilizando como caso de estudio la ciudad de San Carlos de Bariloche, a partir de una clasificación tipológica construida en base a un relevamiento histórico y por muestreo para proponer estrategias de reciclado edilicio para minimizar el consumo de energía. Para tal fin se sistematizan y agrupan las viviendas que comparten características similares como sistemas constructivos, materialidad y consumos energéticos para climatización. Dicha clasificación se presenta mediante un “catálogo de tipologías representativas residenciales” que contiene la matriz base de tipos edilicios, y una “ficha específica y detallada” de cada tipo.The aim of this work is to evaluate the existing residential building stock of the Argentine Patagonia, using as case of study the city of San Carlos de Bariloche, in order to enable future studies that propose strategies to minimize the energy consumption of the sector. To achieve this, houses that share similar characteristics such as construction systems, materiality and energy consumption are systematized and grouped. This classification is presented through a “catalogue of residential representative typologies” that contains the base matrix of building types, and a “specific and detailed file” of each type. This study focuses on a typological classification based on a historical survey and an on-line survey.Fil: Andersen, Micaela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones y Políticas del Ambiente Construido. - Universidad Nacional de La Plata. Instituto de Investigaciones y Políticas del Ambiente Construido; ArgentinaFil: Martini, Irene. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones y Políticas del Ambiente Construido. - Universidad Nacional de La Plata. Instituto de Investigaciones y Políticas del Ambiente Construido; ArgentinaFil: Discoli, Carlos Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones y Políticas del Ambiente Construido. - Universidad Nacional de La Plata. Instituto de Investigaciones y Políticas del Ambiente Construido; Argentin