13,465 research outputs found

    First Collection Records of \u3ci\u3eHippodamia Variegata\u3c/i\u3e (Coleoptera: Coccinellidae) in Minnesota Corn and Soybean

    Get PDF
    The coccinellid Hippodamia variegata (Goeze) (Coleoptera: Coccinellidae) is a relatively recent addition to the North American coccinellid fauna. This species was first reported in 1984 near Montreal, Quebec (Gordon 1987). Since then, its range has expanded beyond northeastern North America with the newest records in the midwestern United States, including Michigan (Gardiner and Parson 2005), Ohio (Pavuk et al. 2007), Wisconsin (Williams and Young 2009), and most recently South Dakota (Hesler and Lundgren 2011). Here we provide the first records of H. variegata in Minnesota. In addition, our records further define the movement pattern of this beetle across the Midwest by documenting its presence in the gap between Wisconsin and South Dakota

    Parsing MetaMap Files in Hadoop

    Get PDF
    The UMLS::Association CUICollector module identifies UMLS Concept Unique Identifier bigrams and their frequencies in a biomedical text corpus. CUICollector was re-implemented in Hadoop MapReduce to improve algorithm speed, flexibility, and scalability. Evaluation of the Hadoop implementation compared to the serial module produced equivalent results and achieved a 28x speedup on a single-node Hadoop system

    Splanchnic vein thrombosis in myeloproliferative neoplasms: Pathophysiology and molecular mechanisms of disease

    Get PDF
    Myeloproliferative neoplasms (MPNs) are the most common underlying prothrombotic disorder found in patients with splanchnic vein thrombosis (SVT). Clinical risk factors for MPN-associated SVTs include younger age, female sex, concomitant hypercoagulable disorders, and the JAK2 V617F mutation. These risk factors are distinct from those associated with arterial or deep venous thrombosis (DVT) in MPN patients, suggesting disparate disease mechanisms. The pathophysiology of SVT is thought to derive from local interactions between activated blood cells and the unique splanchnic endothelial environment. Other mutations commonly found in MPNs, including CALR and MPL, are rare in MPN-associated SVT. The purpose of this article is to review the clinical and molecular risk factors for MPN-associated SVT, with particular focus on the possible mechanisms of SVT formation in MPN patients

    Predicting spatial spread of rabies in skunk populations using surveillance data reported by the public

    Get PDF
    Background: Prevention and control of wildlife disease invasions relies on the ability to predict spatio-temporal dynamics and understand the role of factors driving spread rates, such as seasonality and transmission distance. Passive disease surveillance (i.e., case reports by public) is a common method of monitoring emergence of wildlife diseases, but can be challenging to interpret due to spatial biases and limitations in data quantity and quality. Methodology/Principal findings: We obtained passive rabies surveillance data from dead striped skunks (Mephitis mephitis) in an epizootic in northern Colorado, USA. We developed a dynamic patch-occupancy model which predicts spatio-temporal spreading while accounting for heterogeneous sampling. We estimated the distance travelled per transmission event, direction of invasion, rate of spatial spread, and effects of infection density and season. We also estimated mean transmission distance and rates of spatial spread using a phylogeographic approach on a subsample of viral sequences from the same epizootic. Both the occupancy and phylogeographic approaches predicted similar rates of spatio-temporal spread. Estimated mean transmission distances were 2.3 km (95% Highest Posterior Density (HPD95): 0.02, 11.9; phylogeographic) and 3.9 km (95% credible intervals (CI95): 1.4, 11.3; occupancy). Estimated rates of spatial spread in km/year were: 29.8 (HPD95: 20.8, 39.8; phylogeographic, branch velocity, homogenous model), 22.6 (HPD95: 15.3, 29.7; phylogeographic, diffusion rate, homogenous model) and 21.1 (CI95: 16.7, 25.5; occupancy). Initial colonization probability was twice as high in spring relative to fall. Conclusions/Significance: Skunk-to-skunk transmission was primarily local (< 4 km) suggesting that if interventions were needed, they could be applied at the wave front. Slower viral invasions of skunk rabies in western USA compared to a similar epizootic in raccoons in the eastern USA implies host species or landscape factors underlie the dynamics of rabies invasions. Our framework provides a straightforward method for estimating rates of spatial spread of wildlife diseases

    How Important Is A Postdoc For A Teaching Career?

    Get PDF
    corecore