5 research outputs found
El uso de marcadores de resistencia farmacológica y marcadores poblacionales en malarias importadas como herramienta para valorar la evolución de la estrategia del tratamiento combinado con artemisininas en en continente africano
Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Medicina, Departamento de Medicina. Fecha 19 de Enero de 201
EducaFarma 11.0
Memoria ID2022-036. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2022-2023
Educafarma 10.0
Memoria ID-030. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2021-2022
EducaFarma 9.0
Memoria ID-020 Ayudas de la Universidad de Salamanca para la innovación docente, curso 2020-2021
Imported dengue infection in a Spanish hospital with a high proportion of travelers from Africa: a 9-year retrospective study
Epidemiological data on dengue in Africa are still scarce. We investigated imported dengue infection among travelers with a high proportion of subjects from Africa over a 9-year period. From January 2005 to December 2013, blood samples from travelers with clinical suspicion of dengue were analyzed. Dengue was diagnosed using serological, antigen detection, and molecular methods. Subjects were classified according to birthplace (Europeans versus non-Europeans) and last country visited. Overall, 10,307 serum samples corresponding to 8,295 patients
were studied; 62% were European travelers, most of them from Spain, and 35.9% were non-Europeans, the majority of whom were born in Africa (mainly Equatorial Guinea) and Latin America (mainly Bolivia, Ecuador, and Colombia). A total of 492 cases of dengue were identified, the highest number of cases corresponding to subjects who had traveled from Africa (N = 189), followed by Latin America (N = 174) and Asia (N = 113). The rate of cases for Africa (4.5%) was inferior to Asia (9%) and Latin America (6.1%). Three peaks of dengue were found (2007, 2010, and 2013) which correlated with African cases. A total of 2,157 of past dengue infections were diagnosed. Non-Europeans who had traveled from Africa had the highest rate of past infection (67.8%), compared with non-Europeans traveling from Latin America (38.7%) or Asia (35%). Dengue infection in certain regions of Africa is underreported and the burden of the disease may have a magnitude similar to endemic countries in Latin America.
It is necessary to consider dengue in the differential diagnosis of other febrile diseases in Africa.Sin financiación2.564 JCR (2017) Q2, 6/20 Tropical Medicine, 54/180 Public, Environmental and Occupational HealthUE