The atmospheric emissions in Spain: A regional analysis

The gas emissions to the atmosphere are one the main and more actual environmental problems in the world. The effects of greenhouse gas emissions have been studied and treated recently in the Climate Change Conference in Kyoto. In the approved Kyoto Protocol, the European Union would reduce emissions by 8%, the United States by 7%, and Japan by 6%. The data for each country are used to implement policies and to make global decisions regarding the level of emissions allowed in the future. For this reason, a study more in depth about the origin and level of emissions from a regional perspective become necessary, due to the implications on the regional development. In this paper we will provide detailed information regarding atmospheric emissions in Spanish regions. Moreover, we will show that in many cases the atmospheric emissions are not directly related to the economic situation of each region. For this reason, environmental policies should pay attention to the regional differences within a country.

Oxidative Stress Induced by Excess of Adiposity Is Related to a Downregulation of Hepatic SIRT6 Expression in Obese Individuals

Sirt6 is a member of the sirtuin family involved in physiological and pathological processes including aging, cancer, obesity, diabetes, and energy metabolism. This study is aimed at evaluating the relationship between liver SIRT6 gene expression and the oxidative stress network depending on adiposity levels in Zucker rats, an animal model of metabolic syndrome. We observed that liver-specific SIRT6 expression is reduced in an in vivo model of spontaneous obesity and metabolic syndrome. We also observed that SIRT6 expression in the liver is positively associated with SIRT1 and GST-M2 expressions, two proteins involved in antioxidant protection pathways and inversely related to body weight and plasmatic oxidative status. Interestingly, the SIRT6 expression is upregulated after energy restriction-induced weight loss concomitantly with an improvement in oxidative stress markers. These results suggest that SIRT6 may be a potential therapeutic target for the treatment of obesity and associated metabolic disorders, such as liver disease.Centro de Investigacion Biomedica en Red de Fisiopatologia de la Obesidad y Nutricion (CIBERobn)Instituto de Salud Carlos IIIEuropean Regional Development Fund (FEDER

Combater a pobreza infantil, superando os fatores sociais que estão na origem da desigualdade de acesso ao domínio da língua materna

Este trabalho surge como resultado de um estudo sobre uma intervenção desenvolvida entre 2015 e 2016 com um grupo de crianças, com idades compreendidas entre os 7 e os 9 anos, que frequentavam o 3º ano do 1º ciclo. Trata-se de um grupo de crianças proveniente de famílias pobres, socialmente excluídas, na sua maioria residentes na zona oriental da cidade do Porto em bairros sociais estigmatizados, cujo futuro parece condicionado desde os primeiros anos de vida. A forte interação estabelecida entre a autora e aquele grupo permitiu realizar em condições particulares de grande proximidade, uma intervenção sistemática envolvendo as crianças, a família e a própria Escola, num projeto denominado “Hora do Conto”, que tem como finalidade desenvolver as competências de língua materna, sociais, simbólicas e emocionais. Partiu-se do pressuposto de que, se a inclusão social destas crianças dependia do acesso a aprendizagens e qualificações escolares relevantes, seria igualmente importante reduzir a distância entre o universo escolar e o universo familiar, valorizando e reforçando a participação dos pais no processo educativo dos seus filhos e envolvendo a Escola num processo de partilha de saberes e de experimentação conjunta de práticas pedagógicas susceptíveis de responder às reais necessidades das crianças

Net Reductions or Spatiotemporal Displacement of Intentional Wildfires in Response to Arrests? Evidence from Spain

Research has not examined how the impacts of arrests manifest across space and time in environmental crimes. We evaluate whether arrests reduce or merely spatiotemporally displace intentional illegal outdoor firesetting. Using municipality-level daily wildfire count data from Galicia, Spain, from 1999 to 2014, we develop daily spatiotemporal ignition count models of agricultural, non-agricultural, and total intentional illegal wildfires as functions of spatiotemporally lagged arrests, the election cycle, seasonal and day indicators, meteorological factors, and socio-economic variables. We find evidence that arrests reduce future intentional illegal fires across space in subsequent time periods

An expert patient program to improve the empowerment and quality of life of people with multiple sclerosis: protocol for a multicenter pre-post intervention study

Health education; Multiple sclerosis; Quality of lifeEducación para la salud; Esclerosis múltiple; Calidad de vidaEducació sanitaria; Esclerosi múltiple; Qualitat de vidaIntroduction: Multiple sclerosis (MS) causes a progressive disability, which substantially impacts the quality of life (QoL). Health interventions that meet the needs and demands of people with MS are essential to minimize QoL impairment. Expert patient programs (EPPs) facilitate health-related empowerment through peer learning. Based on a previous focus group study, we designed an EPP for MS coordinated by nursing professionals for implementation in the different MS reference units of Catalonia (Southwestern Europe). This study aims to evaluate the effects on quality of life, disease-related knowledge, and self-management related to the health process of the participants of the Expert Patient Program Catalonia™ for people with multiple sclerosis (EPPC-MS). Methods: Pre-post intervention multicenter clinical study involving 12 groups of 12 participants: six groups including relapsing and six groups including progressive MS patients, with 144 participants from 7 MS reference units from all over Catalonia, organized in six teams. The intervention will consist of nine telematic learning peer-led sessions (one weekly session). The expert patient (EP) leading the sessions will be an individual with MS with disease-related knowledge, who will be further trained by nurses to lead the sessions. Study variables will be measured before and immediately after the intervention and 6 and 12 months after the end of the sessions and will include: QoL, emotional impact, activation of the person, MS-related knowledge, fatigue, habits and lifestyles, health services use, and program-related experience. Baseline characteristics considered will be sociodemographic data, date of MS diagnosis and type, family history, and treatment characteristics. Variables related to disease follow-up will be new relapses and characteristics and changes in the ongoing treatment. The number of sessions attended will also be collected. Study variables will be analyzed using a pre-post comparison. Discussion: Peer-led learning programs led by EP help empower people with chronic conditions and offer them tools to improve their autonomy and QoL. This study’s intervention will be performed remotely, offering advantages both for people with chronic conditions and the healthcare system regarding the facilitation of family and work conciliation, saving time, simplifying attendance to meetings, lowering costs, and using fewer material resources.This study was promoted by the MS unit at Vall d’Hebron Hospital Campus and had no external sponsor. The PhD candidate/first author was supported through the Strategic Plan for Research and Innovation in Health 2016–2020 (PERIS) (ref. BDNS 542793) funded by the Health Department of Catalonia. This study had been partially funded by the Official College of Nurses of Barcelona (www.coib.cat) as part of the Nurse Research Projects Grants (PRN-475/2021). None of the funders were involved in the design of the study, manuscript writing or data collection, and will not be involved in data analysis or interpretation and manuscript writing in the future. The only funders’ requirement is that any publications associate with this study must be open access and deposited in an institutional repository

Linking connectivity of deep brain stimulation of nucleus accumbens area with clinical depression improvements: a retrospective longitudinal case series.

Treatment-resistant depression is a severe form of major depressive disorder and deep brain stimulation is currently an investigational treatment. The stimulation's therapeutic effect may be explained through the functional and structural connectivities between the stimulated area and other brain regions, or to depression-associated networks. In this longitudinal, retrospective study, four female patients with treatment-resistant depression were implanted for stimulation in the nucleus accumbens area at our center. We analyzed the structural and functional connectivity of the stimulation area: the structural connectivity was investigated with probabilistic tractography; the functional connectivity was estimated by combining patient-specific stimulation volumes and a normative functional connectome. These structural and functional connectivity profiles were then related to four clinical outcome scores. At 1-year follow-up, the remission rate was 66%. We observed a consistent structural connectivity to Brodmann area 25 in the patient with the longest remission phase. The functional connectivity analysis resulted in patient-specific R-maps describing brain areas significantly correlated with symptom improvement in this patient, notably the prefrontal cortex. But the connectivity analysis was mixed across patients, calling for confirmation in a larger cohort and over longer time periods

Interacting effects of topography, vegetation, human activities and wildland-urban interfaces on wildfire ignition risk

Effective fire prevention requires a better understanding of the patterns and causes of fire ignition. In this study, we focus on the interacting factors known to influence fire ignition risk, such as the type of veg- etation, topographical features and the wildland-urban interface (WUI; i.e. where urban development meet or intermingle with wildland). We also analyze the human activities and motivations related to fires and whether they differ depending on the type of vegetation and the location within/outside WUI. There were significant interactions between topography, type of vegetation and location within/outside WUI. The risk of ignition was in general higher at lower elevations, and this tendency was more marked in forested land covers (all plantations and open woodlands), with the noticeable exception of native for- ests. North-facing sites had lower fire ignition risk outside the WUI, especially in native forests, while southern aspects showed higher fire ignition risk, especially in open shrublands. However, this effect of the aspect was only significant outside WUI areas. In relation to causes, there were also interactions between human activities/motivations related to fires, the type of vegetation and the location within/out- side WUI. All forestry plantations appeared clustered in relation to fire causes, especially in the WUI, with high incidence of deliberately caused fires related to violent or mentally ill people and rekindle fires. In contrast, native forests, despite structural similarities with forestry plantations, showed more similarity with agricultural areas and open woodlands in relation to fire causes. In shrublands, there was a relatively high incidence of fires related to ranching, especially outside the WUI. This pattern of interactions depicts a complex scenario in relation to fire ignition risk and prompts to the importance of taking this complex- ity into account in order to adjust fire management measures for improved effectiveness