Demonstration system of pumped heat energy storage (PHES) and its round-trip efficiency

Among the known energy storage technologies aiming to increase the efficiency and stability of power grids, Pumped Heat Energy Storage (PHES) is considered by many as a promising candidate because of its flexibility, potential for scale-up and low cost per energy storage unit. Whilst there are numerous demonstration systems under development, as it stands the only PHES demonstration system to be realised at scale is located in Hampshire, UK. This paper aims to present the results and analysis obtained from its commissioning and testing as part of an on-going study. The system was designed to offer a nominal power size of 150 kWe and energy storage capacity of 600 kWhe for an 8-hour storage cycle. This work presents evidence of the system Round-trip efficiency (RTE), which is considered as a fundamental performance metric for large-scale energy storage technologies. Recorded Pressure-Volume (P-V) measurements from recent heat pump/engine testing at part-load offers useful insight in terms of overall performance. Models are also developed to simulate the system to finally predict the performance at full-load conditions. The system and principle of operation are described first, followed by mathematical modelling outlining heat transfer mechanism and associated key losses involved in thermodynamic processes within components, and finally results are presented and compared at different operating conditions using different working gases. The results show good agreement with earlier studies, which indicate that expected electricity-to-electricity RTE is quite comparable to other mature technologies such as Pumped Hydropower Storage and Compressed Air Energy Storage. The cyclic operation of the system is also discussed. One-off storage cycle results in lower RTEs compared to a load-levelling cyclic operation where the efficiency is significantly improved due to stable packed-bed behaviour and better utilisation after an initial transient state

Experimental study and analysis of a novel layered packed-bed for thermal energy storage applications: A proof of concept

This paper presents a study carried out as part of commissioning and testing of world’s first grid-scale 150 kWe Pumped Heat Energy Storage (PHES) demonstration system. The system employs two novel layered packed-bed thermal stores. The present study experimentally investigates one of the stores designated as “hot thermal store”, which has an energy storage density of 1072 MJ/m3 and stores heat at 500 °C and 12 bar. The layered store is an enhancement of a normal packed-bed store and offers a higher degree of thermal stratification. Experiments show that layering results in about 64 % reduction in pressure loss along with yielding considerably narrower thermocline. Round-trip efficiency, storage capacity and utilisation were calculated based on 1st Law analysis considering both simple and layered mode operation at nominal design conditions. Two cycle control scenarios were considered: time-based and temperature-based. In the time-based scenario, the store shows nearly similar performance in both modes. However, in temperature-based scenario, layered mode outperforms. During cyclic operation, layered mode outperforms as it reaches steady-state in merely 3rd cycle, without any loss in efficiency, capacity and utilisation; simple mode yields competitive efficiency but capacity and utilisation deteriorate after each successive cycle and steady-state is achieved in 20th cycle. 2nd Law analysis was additionally performed to gain insight into various losses and their impact on the performance

Were late Gomphotheres (Plio-Pleistocene) of the Siwaliks at more Stress as compared to early Gomphotheres (middle to late Miocene)?

Gomphotheres existed in the Siwaliks from the middle Miocene (14.2Ma) to the middle Pleistocene (0.8Ma) and became extinct later on. In this paper, we tried to discuss the reasons of such extinction of gomphotheres in the lower Pleistocene time span by considering Linear Enamel Hypoplasia (LEH) among 114 isolated tooth samples to assess whether ecological changes correlate with the stress factor in gomphotheres. For this purpose, the Siwalik gomphotheres were divided into two Groups viz. early gomphotheres (middle Miocene to late Miocene) and late gomphotheres (Pliocene to middle Pleistocene). We presented the hypothesis, that as the gomphotheres are characterized by the brachydonty and relied on browsing for their feeding while inhabiting the semi forest land setting thus, expected to have higher stress in Plio-Pleistocene time span as vegetational change around ~6 Ma may have exerted stress on late gomphotheres. The results for the occurrence of frequency of LEH indicated severe ecological stress in late gomphotheres (33%). The significant differences were found (P < 0.05) among the early gomphotheres and late gomphotheres which can be correlated to the vegetational change from C3 to C4, higher aridity indices and intensified seasonality after the late Miocene vegetational shift which may have resulted in substantial faunal turnover, extinction and speciation. We assume that such palaeoecological changes forced a competition with more pronounced grazers like of family Elephantidae and Bovidae resulting in extinction of gomphotheres during the late Pleistocene in the Siwaliks of Pakistan

Safety and efficacy of ketamine xylazine along with atropine anesthesia in BALB/c mice

Anesthetics are an indispensable prerequisite for surgical intervention and pharmacological animal studies. The objective of present study was to optimize the dose of ketamine (K) and xylazine (X) along with atropine sulfate (A) in order to achieve surgical tolerance in BALB/c mice. Several doses of ketamine (100, 150, 200 mg/kg) and xylazine (10, 15, 20 mg/kg) were mixed and combination of nine doses (K/X: 100/10, 100/15, 100/20, 150/10, 150/15, 150/20, 200/10,200/15,200/20) were evaluated (n=9 per combination). A constant dose of atropine (0.05 mg/kg) was also used to counter side effect. Timerelated parameters were evaluated on the basis of reflexes. KX at dose 200/20 mg/kg produced surgical tolerance in all nine mice with duration 55.00±6.87 minutes. The induction time 0.97±0.09 minutes, sleeping time 90.67±5.81 minutes and immobilization time (102.23±6.83 minutes) were significantly higher than all combination. However, this combination was considered unsafe due to 11 % mortality. While, KX at dose 200/15 mg/kg results in none of the mortality, so was considered as safe. Moreover, this combination produces surgical tolerance in 89 % mice with duration (30.00±7.45 minutes). It was concluded that KX at dose 200/15 mg/kg along with atropine 0.05 mg/kg is safe for performing surgical interventions in BALB/c mice

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

SummaryBackground Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatoryactions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19.Methods In this randomised, controlled, open-label, adaptive platform trial (Randomised Evaluation of COVID-19Therapy [RECOVERY]), several possible treatments were compared with usual care in patients admitted to hospitalwith COVID-19 in the UK. The trial is underway at 176 hospitals in the UK. Eligible and consenting patients wererandomly allocated to either usual standard of care alone or usual standard of care plus azithromycin 500 mg once perday by mouth or intravenously for 10 days or until discharge (or allocation to one of the other RECOVERY treatmentgroups). Patients were assigned via web-based simple (unstratified) randomisation with allocation concealment andwere twice as likely to be randomly assigned to usual care than to any of the active treatment groups. Participants andlocal study staff were not masked to the allocated treatment, but all others involved in the trial were masked to theoutcome data during the trial. The primary outcome was 28-day all-cause mortality, assessed in the intention-to-treatpopulation. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936.Findings Between April 7 and Nov 27, 2020, of 16 442 patients enrolled in the RECOVERY trial, 9433 (57%) wereeligible and 7763 were included in the assessment of azithromycin. The mean age of these study participants was65·3 years (SD 15·7) and approximately a third were women (2944 [38%] of 7763). 2582 patients were randomlyallocated to receive azithromycin and 5181 patients were randomly allocated to usual care alone. Overall,561 (22%) patients allocated to azithromycin and 1162 (22%) patients allocated to usual care died within 28 days(rate ratio 0·97, 95% CI 0·87–1·07; p=0·50). No significant difference was seen in duration of hospital stay (median10 days [IQR 5 to >28] vs 11 days [5 to >28]) or the proportion of patients discharged from hospital alive within 28 days(rate ratio 1·04, 95% CI 0·98–1·10; p=0·19). Among those not on invasive mechanical ventilation at baseline, nosignificant difference was seen in the proportion meeting the composite endpoint of invasive mechanical ventilationor death (risk ratio 0·95, 95% CI 0·87–1·03; p=0·24).Interpretation In patients admitted to hospital with COVID-19, azithromycin did not improve survival or otherprespecified clinical outcomes. Azithromycin use in patients admitted to hospital with COVID-19 should be restrictedto patients in whom there is a clear antimicrobial indication

Were late Gomphotheres (Plio-Pleistocene) of the Siwaliks at more Stress as compared to early Gomphotheres (middle to late Miocene)?

Gomphotheres existed in the Siwaliks from the middle Miocene (14.2Ma) to the middle Pleistocene (0.8Ma) and became extinct later on. In this paper, we tried to discuss the reasons of such extinction of gomphotheres in the lower Pleistocene time span by considering Linear Enamel Hypoplasia (LEH) among 114 isolated tooth samples to assess whether ecological changes correlate with the stress factor in gomphotheres. For this purpose, the Siwalik gomphotheres were divided into two Groups viz. early gomphotheres (middle Miocene to late Miocene) and late gomphotheres (Pliocene to middle Pleistocene). We presented the hypothesis, that as the gomphotheres are characterized by the brachydonty and relied on browsing for their feeding while inhabiting the semi forest land setting thus, expected to have higher stress in Plio-Pleistocene time span as vegetational change around ~6 Ma may have exerted stress on late gomphotheres. The results for the occurrence of frequency of LEH indicated severe ecological stress in late gomphotheres (33%). The significant differences were found (P \u3c 0.05) among the early gomphotheres and late gomphotheres which can be correlated to the vegetational change from C3 to C4, higher aridity indices and intensified seasonality after the late Miocene vegetational shift which may have resulted in substantial faunal turnover, extinction and speciation. We assume that such palaeoecological changes forced a competition with more pronounced grazers like of family Elephantidae and Bovidae resulting in extinction of gomphotheres during the late Pleistocene in the Siwaliks of Pakistan

The development of a screen valve for reciprocating heat pump/engine applications

A novel screen valve with rectilinear ports is presented for use in advanced high-efficiency compressors, expanders, heat pumps, or engines. The novel design aims to minimize the pumping losses generated as the working gas flows through the valve by maximizing the effective opening cross-sectional area. In this work, various screen valve configurations have been investigated through a series of experimental tests conducted on a heavily modified research engine for high-speed, high-pressure valve testing. The valves were designed and tested to operate efficiently at both low and high engine speeds ranging between 1500 and 3000 rpm. The valve dynamics were optimized to meet two high-level criteria for performance—namely (1) high speed metrics quantified by its percentage of “maximum dynamic pressure” and (2) low speed metrics quantified by the valve “minimum closure angle.” The valves were tested to meet the objective of avoiding any friction-locking issues associated with the valve retainer design. Multiple tests were carried out in pursuit of attaining an improved design. The work concluded that by including a carrier frame (rather than a retainer frame) and upstands on the valve seat, the valve performance was improved significantly. The best design yielded results of 50.4% of maximum dynamic pressure and 25.1° as the minimum closure angle

Development of a hybrid mixed-mode solar dryer for product drying

Gefördert durch den Publikationsfonds der Universität Kasse