Antagonistic Effect of Native Bacillus Isolates against Black Root Rot of Faba Bean

Faba bean (Vicia faba L.) is one of the most important pulse crops grown in eastern Africa. Black root rot (Fusarium solani) is known to cause great yield losses in faba bean, especially in the highlands of Ethiopia. The objective of this study was to evaluate the biological control ability of native Bacillus species on the basis of their antagonistic effects against F. solani. The study was conducted in vitro and in a greenhouse. All tested Bacillus isolates significantly (P<0.05) reduced radial mycelial growth of the pathogen. Seven bacterial isolates restricted growth of the pathogen to <14 mm diameter, and showed 39-44% efficacy over the positive control. Isolate BP048 was the most effective, with 43.6% efficacy. The lowest inhibitory effects, 15.5 and 27.8%, were recorded from isolates BS083 and BS0102, respectively. The culture filtrate of the bacterial isolates also inhibited F. solani spore germination. In vivo, the isolates significantly reduced severity of black root rot on artificially inoculated faba bean seedlings. The antagonist Bacillus isolates kept black root rot severity low with more than 50% disease suppression, compared to the untreated control.Keywords: Ethiopia, Fusarium solani, Vicia faba

Newborn care seeking practices in Central and Southern Ethiopia and implications for community based programming

Background: In Ethiopia, close to 120,000 newborns die annually and newborn mortality now constitutes 42% of under-five deaths. The use of health care for newborn illnesses is very limited.Objective: To investigate local perspectives and practices related to newborn care-seeking and the factors affecting them.Methods: Key informant interviews with grandmothers and in-depth interviews with mothers, TBAs and fathers were used to collect data in four communities in Sidama Zone, Southern Nations, Nationalities and Peoples Region and East Shewa Zone and West Arsi Zone in Oromia Region. Analysis consisted of manual thematic coding of the data and synthesis for write-up.Results: Locally recognized signs and types of illness only partially conform to medically recognized danger signs. Households apply home therapies, traditional healers or health facilities to get treatment for sick newborns. Lack of resources, transportation and appropriate treatment are barriers to making use of health facilities.Conclusion: Local conceptions of newborn illnesses, inadequate recognition of danger signs, using traditional treatment, and lack of financial resources, transportation and appropriate treatment constrain or delay resorting to health facilities for newborn illnesses

Shear Zone-Hosted Base Metal Mineralization near Abraha Weatsebaha-Adidesta and Hawzein, Tigray Region, Northern Ethiopia

Low-grade basement rocks of Neoproterozoic age with well developed shear zones and posttectonic granitic intrusives from Hawzien area of northern Ethiopia were studied for field characteristics, mineralogy, textures, alteration assemblages and geochemistry to explore theirpotential for base metal mineralization. The basement rocks includes metavolcanic (mafic to felsic), metavolcaniclastic and metasedimentary rocks. The intrusive post-tectonic granitoids mark the end of Proterozoic. Field observation and petrographic data indicate the presence of NS, NE-SW trending shear zones; hydrothermal quartz (±calcite) veins of different generations; malachite stains; alterations like chloritisation, kaolinization, epidotization, sericitization; and presence of base metal sulfides in association with quartz and calcite veins. Geochemistry of surface and drill core samples indicate enrichment of zinc in shear zones with low concentrations of copper, lead, gold, arsenic and silver. Zn-rich base metal mineralization with Pb-Cu-Fe (±Ag-As-Au) is related to D2 deformation. Barite veins are although common, conspicuously occurring in E-W trending veins. Post-tectonic granitoids are facilitating the  hydrothermal activity and the source rock compositions controlling the  nature of the mineralization. A paragenetic scheme is suggested on the basis of texture, mineral association, alteration and deformation. Keywords: Abraha-Weatsebaha, Tigray, Ethiopia, Neoproterozoic, Shear zones, Paragenesis, Sulfide mineralizatio

Thoracic empyema: Cause and Treatment Outcome at Gondar University Teaching Hospital, Northwest Ethiopia

Background: Despite improved antimicrobial therapy and multiple options for drainage of infected pleural space, thoracic empyema (TE) continues to cause significant morbidity and mortality. The objectives of this study were to assess the causes and treatment outcome of patients with thoracic empyema.Methods: Patients aged ≥ 13year with TE who were admitted to Gondar University Teaching Hospital, Northwest Ethiopia, from Nov 1999 to Dec 2007 were included. Retrospectively, medical records were reviewed and demographic and clinical data were collected.Results: Records of 81 patients were analyzed; majority (82%) were below the age 50 year. The mean duration of symptoms prior to presentation and hospital stay was 97.4 and 38days, respectively. HIV/AIDS was detected in 60%. Causes of empyema were pulmonary tuberculosis (56%), pneumonia (36%) and lung abscess (7%). Closed chest tube was inserted in 86% of cases and was successful in 93% of them. Case-fatality was 12% and poor outcome occurred in 26%.Conclusions: Early identification of TE and aggressive management with antibiotics or antituberculosis, drainage with chest tube, and surgical treatment when closed tube drainage fails is recommended to improve the high mortality and morbidity

Climate change, income sources, crop mix, and input use decisions: Evidence from Nigeria

This paper combines panel data from nationally representative household-level surveys in Nigeria with long-term satellite-based spatial data on temperature and precipitation using geo-referenced information related to households. It aims to quantify the impacts of climate change on agricultural productivity, income shares, crop mix, and input use decisions. We measure climate change in harmful degree days, growing degree days, and changes in precipitation using long-term (30 year) changes in temperature and precipitation anomalies during the crop calendars. We find that, controlling for other factors, a 15 percent (one standard deviation) increase in change in harmful degree days leads to a decrease in agricultural productivity of 5.22 percent on average. Similarly, precipitation change has resulted in a significant and negative impact on agricultural productivity. Our results further show that the change in harmful degree days decreases the income share from crops and nonfarm self-employment, while it increases the income share from livestock and wage employment. Examining possible transmission channels for this effect, we find that farmers change their crop mix and input use to respond to climate changes, for instance reducing fertilizer use and seed purchases as a response to increases in extreme heat. Based on our findings, we suggest policy interventions that incentivize adoption of climate-resilient agriculture, such as small-scale irrigation and livelihood diversification. We also propose targeted pro-poor interventions, such as low-cost financing options for improving smallholders’ access to climate-proof agricultural inputs and technologies, and policy measures to reduce the inequality of access to livelihood capital such as land and other productive assets

Prevention and treatment of suspected pneumonia in Ethiopian children less than five years from household to primary care.

AIM: Ethiopia has implemented the integrated community case management to reduce mortality in childhood diseases. We analysed prevention, care seeking and treatment of suspected pneumonia from household to health facility in Ethiopia. METHODS: Analyses were based on a survey in four regions that included modules covering 5714 households, 169 health posts with 276 health extension workers and 155 health centres with 175 staff. Caregivers of children aged 2-59 months responded to questions on awareness of services and care seeking for suspected pneumonia. Pneumonia-related knowledge of health workers was assessed. RESULTS: When a child had suspected pneumonia, 46% (95% CI: 25,68) sought care at health facilities, and 27% (95% CI: 12,51) received antibiotics. Forty-one per cent had received full immunisation. One-fifth (21%, 95%: 19,22) of the caregivers were aware of pneumonia treatment. Sixty-four per cent of the health extension workers correctly mentioned fast or difficult breathing as signs of suspected pneumonia, and 88% suggested antibiotics treatment. CONCLUSION: The caregivers' awareness of suspected pneumonia treatment and the utilisation of these services were low. Some of the health extension workers were not knowledgeable about suspected pneumonia. Strengthening primary health care, including immunisation, and enhancing the utilisation of services are critical for further reduction of pneumonia mortality

Direct WIMP identification: Physics performance of a segmented noble-liquid target immersed in a Gd-doped water veto

We evaluate background rejection capabilities and physics performance of a detector composed of two diverse elements: a sensitive target (filled with one or two species of liquefied noble gasses) and an active veto (made of Gd-doped ultra-pure water). A GEANT4 simulation shows that for a direct WIMP search, this device can reduce the neutron background to O(1) event per year per tonne of material. Our calculation shows that an exposure of one tonne $\times$ year will suffice to exclude spin-independent WIMP-nucleon cross sections ranging from $10^{-9}$ pb to $10^{-10}$ pb.Comment: 17 pages, 5 figures. Version accepted for publication in JCA

Roles and Responsibilities in Newborn Care in four African Sites.

To explore roles and responsibilities in newborn care in the intra- and postpartum period in Nigeria, Tanzania and Ethiopia. Qualitative data were collected using in-depth interviews with mothers, grandmothers, fathers, health workers and birth attendants and were analysed through content and framework analyses. We found that birth attendants were the main decision-makers and care takers in the intrapartum period. Birth attendants varied across sites and included female relatives (Ethiopia and Nigeria), traditional birth attendants (Tanzania and Nigeria), spiritual birth attendants (Nigeria) and health workers (Tanzania and Nigeria). In the early newborn period, when the mother is deemed to be resting, female family members assumed this role. The mothers themselves only took full responsibility for newborn care after a few days or weeks. The early newborn period was protracted for first-time mothers, who were perceived as needing training on caring for the baby. Clear gender roles were described, with newborn care being considered a woman's domain. Fathers had little physical contact with the newborn, but played an important role in financing newborn care, and were considered the ultimate decision-maker in the family. Interventions should move beyond a focus on the mother-child dyad, to include other carers who perform and decide on newborn care practices. Given this power dynamic, interventions that involve men have the potential to result in behaviour change

Drug sensitivity of clinical isolates of Mycobacterium tuberculosis and its association with bacterial genotype in the Somali region, Eastern Ethiopia

Background: Drug resistance is becoming a major bottleneck for tuberculosis (TB) control programs in countries with high TB burdens. Although several studies were conducted on the drug sensitivity of Mycobacterium tuberculosis (M. tuberculosis) in central Ethiopia, there is a lack of data on the drug sensitivity of M. tuberculosis in the peripheral regions of the country including in the Somali region. Therefore, the objective of this study was to evaluate the drug sensitivity of M. tuberculosis and its association with bacterial genotype and evaluate the performance of Xpert MTB/RIF (Xpert) in detecting resistance to rifampicin (RIF). Methods: A total of 302 M. tuberculosis were tested using the BD BACTEC-Mycobacteria Growth Indicator Tube 960 (MGIT 960) system for their drug sensitivity to the first-line anti-TB drugs. Besides, the drug sensitivity of 10 multidrug-resistant (MDR) M. tuberculosis isolates was evaluated for the second-line anti-TB drugs. Additionally, 177 of the 302 isolates were tested for genotypic drug resistance using Xpert. Chi-square and Fisher's exact tests were used for the evaluation of the association between variables and drug sensitivity. Results: The overall prevalence of resistance to at least one drug was 11.6% (95% CI: 7.9-15.2%), while the prevalence of MDR was 3.3% (95% CI: 1.3-5.3%). Two of the 10 MDR isolates were resistant to capreomycin. The spoligotype Shared International Type (SIT) 149 was significantly associated with either monoresistance or MDR (p < 0.05). Of the 177 isolates tested by Xpert, 6.2% (11/177) were RIF-resistant. Discordant between Xpert and MGIT 960 was observed in one isolate and linked with probe-binding delay (DeltaCT max = 5.8). The sensitivity and specificity of the Xpert assay were 100 and 99.4%, respectively, while its positive and negative predictive values were 90.9 and 100%, respectively. Conclusion: The magnitude of MDR M. tuberculosis in the Somali region of Ethiopia was higher than the national prevalence of MDR-TB warranting the strengthening of the TB control program in the Somali region. Besides, drug resistance was associated with SIT 149 spoligotype (genotype). The Xpert assay was observed to have high sensitivity and specificity in detecting RIF-resistant M. tuberculosis, which is encouraging for its application widely

Entry points for enabling gender equality in agricultural and environmental innovation

Men and women on average report growing power and freedom to shape their lives as well as declining poverty in their villages across the 137 GENNOVATE village-level case studies. Wider forces in the macro environments as well as improvements in rural livelihoods due to agricultural innovation contribute importantly to these promising trends. Yet, beneath these broad patterns, the GENNOVATE data show strong differences in how men and women – and their communities – experience and benefit from innovation processes. The research communities experiencing more inclusive innovation processes and rapid poverty reduction offer valuable lessons on which agricultural research and development (R&D) can build