Effect of Perceived Nursing Work Environment on Nurses Job Outcomes at Primary Health Care Centers – Jeddah

During the new and modern era, the organizations are facing many challenge and diversity of workforces in the health care system because the nursing environment has energetic characteristics for nurses.  In addition, nurses are exposed to an unfavorable environment that affects their practice. Therefore, the healthy nursing work environment is essential for increasing satisfaction of their professional nurses needs through attracting, retaining, and rendering quality of patient care in the hospitals. This study aims to investigate the perception of the nursing work environment on nurses' job outcomes at primary health care centers- Jeddah. A descriptive correlational namely cross-sectional design was employed to collect data using non-probability convenience sampling technique from a group of nurses who accept to participate in the study and working at three primary health care centers affiliated to the Ministry of National Guard in Jeddah region namely; Al-Bahra, Alwaha, and Al-Eskan. The questionnaires were administered to the nurses for data collection using socio-demographic characteristics, Revised Nurse Working Index (NWI-R), Nurses' job outcome was measured through of (a) job satisfaction, (b) intention to leave, and (c) quality of nursing care. Statistical analysis was done using SPSS 20.0.  Also, data was analyzed by using descriptive statistics such as mean and standard deviation and inferential statistics such t-tests (two-tailed) and one way analysis of variance (ANOVA) and Pearson correlations were conducted to investigate the relationships of nursing work  environments and the nurses job outcome. In this study the level of significant was set at 0.05.The present study finds that majority of the nurses had a highest percentage of nursing work environment dimensions. For achieving a high level of nursing work environment it is found that there is statistically significant relationship with nurses' job outcomes in term of job satisfaction. Most of the nurses were satisfied with the work and have the highest means scores in term of growth satisfaction, followed by Co-workers and supervision. Job security was reported to have lowest means scores by nurses. There was a significant relationship between socio-demographic variables with the nursing work environment and nurses' job outcomes in term of primary health care centers, educational qualification, and age group. This study recommended that Hospital administrators should advocate and support the policies and regulations that foster nurses' satisfaction by providing a strong nursing work environment and recognizing more productivity for delivering nursing care in primary health care settings Keyword: nursing work environment, job satisfaction, intention to leave, primary health care DOI: 10.7176/JHMN/63-07 Publication date:June 30th 201

Association Between Lipid Profile and Diabetic Foot Ulcer

Diabetic foot ulcer is a serious disabling consequence of Diabetes Mellitus. They are characterized by the breakdown of skin and underlying tissues in the feet, and are a major cause of lower limb amputations. Various risk factors have been identified for the development of diabetic foot ulcers, including poor glycemic control, peripheral neuropathy, peripheral arterial disease, and impaired wound healing. it is considered that the lipid profile is one of many factors that contribute to the formation and progression of diabetic foot ulcers. To stratify the incidence of diabetic foot ulcers (DFUs), biomarkers are required. The aim of this review is to assess the relationship between the risk of DFU and lipid profile in diabetic patients

Efficacy of tranexamic acid administration in traumatic brain injury patients: A review

BackgroundAnti-fibrinolytic medications decrease traumatic intracranial haemorrhage (ICH). Tranexamic acid (TXA) is an anti-fibrinolytic, which recently has shown effectiveness in management of traumatic haemorrhage‎.AimsTo summarize the randomized control trials (RCTs) that evaluate the efficacy of tranexamic acid administration in traumatic brain ‎injury (TBI) patients‎.‎Methods An electronic literature review, including PubMed, Google Scholar, and EBSCO that examining RCTs, observational, and experimental studies which study the efficacy of TXA administration in (TBI) patients.ResultsThe current review included 7 randomized studies reported the efficacy of TXA in management of TBI. TXA limit secondary brain injury by preventing the expansion of ICH. Administration of TXA exhibited a tendency to decrease head trauma-related mortality.ConclusionTXA significantly lower the risk of ICU expansion m and prevent brain injury related deaths

SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues

Variability in SARS-CoV-2 susceptibility and COVID-19 disease severity between individuals is partly due to genetic factors. Here, we identify 4 genomic loci with suggestive associations for SARS-CoV-2 susceptibility and 19 for COVID-19 disease severity. Four of these 23 loci likely have an ethnicity-specific component. Genome-wide association study (GWAS) signals in 11 loci colocalize with expression quantitative trait loci (eQTLs) associated with the expression of 20 genes in 62 tissues/cell types (range: 1:43 tissues/gene), including lung, brain, heart, muscle, and skin as well as the digestive system and immune system. We perform genetic fine mapping to compute 99% credible SNP sets, which identify 10 GWAS loci that have eight or fewer SNPs in the credible set, including three loci with one single likely causal SNP. Our study suggests that the diverse symptoms and disease severity of COVID-19 observed between individuals is associated with variants across the genome, affecting gene expression levels in a wide variety of tissue types

A first update on mapping the human genetic architecture of COVID-19

peer reviewe

The Effectiveness of Facial Cues for Automatic Detection of Cognitive Impairment Using In-the-wild Data

The development of automatic methods for the early detection of cognitive impairment (CI) has attracted much research interest due to its crucial role in helping people get suitable treatment or care. People with CI may experience various changes in their facial cues, such as eye blink rate and head movement. This thesis aims to investigate the use of facial cues to develop an automatic system for detecting CI using in-the-wild data. Firstly, the 'in-the-wild data' term is defined, and associated challenges are identified by analysing datasets used in previous work. In-the-wild data can affect the reliability of the performance of state-of-the-art approaches. Second, this thesis investigates the automatic detection of neurodegenerative disorder, mild cognitive impairment and functional memory disorder, showing the applicability of detecting health conditions with similar symptoms. Then, a novel multiple thresholds (MTs) approach for detecting an eye blink rate feature is introduced. This approach addresses in-the-wild data challenges by generating multiple thresholds, resulting in a vector of blink rates for each participant. Then, the feasibility of this feature in detecting CI is examined. Other features considered are head turn rate, head turn statistical features, head movement statistical features and low-level features. The results show that these facial features significantly distinguish different health conditions