Anti-fungal bandages containing cinnamon extract

© 2019 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.Cinnamon-containing polycaprolactone (PCL) bandages were produced by pressurised gyration and their anti-fungal activities against Candida albicans were investigated. It was found that by preparing and spinning polymer solutions of cinnamon with PCL, fibres capable of inhibiting fungal growth could be produced, as observed in disk diffusion tests for anti-fungal susceptibility. Fascinatingly, compared with raw cinnamon powder, the novel cinnamon-loaded fibres had outstanding long-term activity. The results presented here are very promising and may indeed accelerate a new era of using completely natural materials in biomedical applications, especially in wound healing.Peer reviewe

Correlation between oral health-related quality of life (OHQoL) and oral disorders in a Turkish patient population

Objectives: The purpose of the present study is to determine the nature of the complaints that bring patients to our clinic and to what degree these complaints affect their quality of life (QoL). We also aimed to determine any associations between gender, education or harmful habits and each patient?s oral health-related quality of life (OHQoL). Methods: A total of 1090 patients, consisting of 651 females (59.7 %) and 439 males (40.3 %), were included in this study. Of these patients, 220 constituted healthy controls. Two patient-centered outcome measures, the 14 item OHIP-14 and the 16 item OHQoL-UK measures were used. Results: Most of the patients presented with toothache and caries (50.1 %), 11.2 % had suffered tooth loss and had denture needs, 9.2 % had periodontal problems, 1.8 % had temporomandibular joint (TMJ) disorders, 3.8 % had buried third molars, 2.4 % had orthodontic and aesthetic disorders, 1.3 % had suffered injury due to trauma, and 20.2 % came only for control checkups. OHQoL was best in the control group and the worst in patients who had suffered trauma. In addition, we noted correlations between gender, education and harmful habits, and that of the patient?s oral health-related quality of life. Conclusion: According to our results, OHQoL is associated with the oral complaints of patients. Furthermore, OHQoL may not only be associated with the oral health status of patients, but factors such as gender, education and harmful habits may also play a role

Nazal kavite ve osteomeatal kompleks anatomik varyasyonları

Objectives: The maxillary sinuses are important anatomical structures for dental procedures in dentistry. The normal function of the sinuses is effective in the success of these dental procedures. The continuation of the normal functions of the paranasal sinuses, the maxillary and osteomeatal complex (OMC) has an important role. In this study, we aimed to investigate the frequency of osteomeatal complex anatomic variations with cone-beam computed tomography. Material and Methods: In this retrospective study, in cone-beam computed topographies of 280 patients (154 men, 126 women), anatomic variations of paranasal sinuses (deviated septum, inferior turbinate hypertrophy, concha bullosa, paradoxical middle turbinate, Agger nasi, Haller’s cell, Onodi cell, pneumatized uncinate process (uncinate bulla), pneumatized crista galli, pneumatized septum) were analyzed. Results: In our study, septal deviation 85%; inferior turbinate hypertrophy 48.6%; middle concha bullosa 40%; Agger nasi cells 28.6%; Haller’s cells 9.6%; pneumatized septum 4.6%; paradoxical middle turbinate 2.5%; pneumatized uncinate process 2.5%; pneumatized crista galli 1.4%; Onodi %1.1 were found. Conclusion: Variations of the osteomeatal complex due to the effect of the paranasal sinuses should be considered in maxillary dental implant planning. Keywords: Anatomic variation, osteomeatal complex, cone-beam computed tomography.   ÖZETAmaç: Diş hekimliğinde maksiller sinüsler dental girişimler için önemli anatomik yapılardır. Bu girişimlerin başarısında sinüslerin normal fonksiyonları etkilidir. Maksiller ve diğer paranazal sinüslerin normal fonksiyonlarını sürdürmesinde osteomeatal kompleks (OMK) önemli bir role sahiptir. Bu çalışmada nazal fossa ve osteomeatal kompleks anatomik varyasyonlarının konik ışınlı bilgisayarlı tomografi (KIBT) ile sıklığının araştırılması amaçlandı. Gereç ve Yöntem: Bu retrospektif çalışmada 280 hastanın (154 erkek, 126 kadın) konik ışınlı bilgisayarlı tomografilerinde paranazal sinüslerin anatomik varyasyonları (Agger nazi hücresi, Haller hücresi, Onodi hücresi, orta konka bulloza, paradoksal orta konka, pnömatize unsinat proses (uncinate bulla), pnömatize krista galli, pnömatize septum, alt konka hipertrofisi, septum deviasyonu) incelendi. Bulgular: Çalışmamızda septum deviasyonu %85; alt konka hipertrofisi %48.6; orta konka bulloza %40; Agger nazi hücreleri %28.6; Haller hücreleri %9.6; pnömatize septum %4.6; paradoksal orta konka %2.5; unsinat proses pnömatizasyonu %2.5; pnömatize krista galli %1.4; Onodi hücresi %1.1 olarak bulundu. Sonuç: Osteomeatal kompleks varyasyonları paranasal sinüslere olan etkisi nedeniyle maksiller dental implant planlamalarında dikkate alınmalıdır

Macromol. Mater. Eng. 3/2018

Bacterial cellulose blended polymeric fibrous bandages made in a novel way, from a solution subjected to gyration under pressure to directly weave the bandages. The products show cellular attraction, mechanical and swelling properties in preliminary tests and heralds a very promising new route for the manufacture of wound care bandages. This is reported by Esra Altun, Mehmet Onur Aydogdu, Fatma Koc, Maryam Crabbe‐Mann, Francis Brako, Rupy Kaur‐Matharu, Gunes Ozen, Serap Erdem Kuruca, Ursula Edirisinghe, Oguzhan Gunduz, and Mohan Edirisinghein

Novel Making of Bacterial Cellulose Blended Polymeric Fiber Bandages

Bacterial cellulose (BC) is a very promising biological material. However, at present its utilization is limited by difficulties in shape forming it. In this Communication, it is shown how this can be overcome by blending it with poly(methylmethacrylate) (PMMA) polymer. BC:PMMA fibers are produced by pressurized gyration of blended BC:PMMA solutions. Subsequently, BC:PMMA bandage‐like scaffolds are generated with different blends. The products are investigated to determine their morphological and chemical features. Cell culture and proliferation tests are performed to obtain information on biocompatibility of the scaffolds

İnönü üniversitesi dişhekimliği fakültesine başvuran hastalarda taurodontizm görülme prevalansının retrospektif olarak değerlendirmesi

Objectives: The objective of this study was to determine the prevalence of taurodontism in patients admitting to Dentistry Faculty of Inonu University, and to examine the localization, distribution and the gender differences of taurodontism. Materials and Methods: This retpospective study was carried out using panoramic radiographs of the patients who came to İnönü Univercity Faculty of Dentistry, Departman of Dentomaksillofacial Radiology for dental problems.Results: Among the evaluated of 981 patients, 64 taurodont teeth were found in 31 patients, 8 of them were male (%25.8) and 23 of them were female(%74.2). Ten of cases were hypotaurodont (%15.63), 13 were mesotaurodont (%20.31),  26 were hypertaurodont (%40.62)  and 15 cases were  pyramidal (%23.44). The maxilla was affected more frequently than the mandible, the most common taurodont tooth was the  mandibular 2nd molar.Conclusions: As a result, the prevalence of taurodontism was found to be %3.2. ÖZETAmaç: Bu çalışmanın amacı İnönü Üniversitesi Diş Hekimliği Fakültesine başvuran hastalarda taurodontizm prevalansını belirlemek, lokalizasyonu, dağılımını, cinsiyetler arasındaki farklılığını incelemektir.Gereç ve Yöntem: Bu çalışmada çeşitli dental problemler nedeniyle İnönü Üniversitesi Diş Hekimliği Fakültesi Ağız Diş ve Çene Radyolojisi bölümüne başvuran hastaların dijital panoramik radyografları retrospektif olarak değerlendirildi.Bulgular:  Çalışmaya dahil edilen 981 hastadan 8’i erkek (%25,8), 23’ü kadın (%74,2), toplam 31 hastada 64 taurodont diş bulundu. Bunların 10 tanesi hipotaurodont (%15,63), 13 tanesi mezotaurodont (%20,31), 26 tanesi hipertaurodont (%40,62)   ve 15 tanesi piramidal (%23,44)  olarak belirlendi. Mandibulada maksillaya oranla daha sık görülmüştür. Taurodontizmin en sık rastlandığı diş mandibular 2. molar diştir.Sonuçlar: Taurodont diş prevalansı %3,2 oranında bulundu

Cone beam computed tomography imaging guides for ortodontic miniscrew placement

The aim of this retrospective study is to present a guide for the clinicians by detecting the best mini screw placement areas with the measurement of cortical bone thickness in the patients who have cone beam computed tomography (CBCT) images. Additionally to be protected from root damage and a potential damage to environmental anatomic tissues, related measurements will also be held in the determined areas.This study has been evaluated by using the images of 52 patients taken by cone beam computed tomography for diagnosis and cure.In the mandibular measurements which were done by using CBCT, the buccal cortical bone thickness has been found out to increase while going towards the posterior region and going down to the apical region at the same area. In addition, it was observed mostly between second premolar and first molar teeth at the farthest area from the top of the crest, along the mandibular canal. The distance between base of the nose and maxillar sinus floor to the hill of the crest has also been observed that decreased towards the posterior region.Although it can vary according to the person, in mini screw applications, mandibular cortical bone structure and the interradicular range is more suitable than the upper jaw. To be protected from the potential complications and for a better stability, radiologic analysis is recommended to the patient before the mini screw placement. [Med-Science 2019; 8(4.000): 931-5

The effects of proprioceptive neuromuscular facilitation, myofascial releasing maneuvers and home exercises on pain and jaw function in patients with bruxism

To evaluate the effects of proprioceptive neuromuscular facilitation exercises, myofascial releasing techniques and home exercises on temporamandibular joint pain and jaw function in patients with bruxism. This randomized, controlled experimental trial included 52 patients (42 females, 10 males) aged 16 to 50 years (a mean age of 28.9 ± 11.05 years) with bruxism. The patients were separated into 3 groups, as Group 1 (n: 20) treated with proprioceptive neuromuscular facilitation exercises + myofascial release techniques + home exercise, Group 2 (n: 15) treated with myofascial release + home exercise and Group 3 (n: 17), as the control group, treated with the classical methods of occlusal splint, antidepressant drugs and botox. The Visual Analog Scale, Jaw Restriction Scale and Oral Habits Checklist were used to evaluate pain, restriction of jaw movements and bad habits, respectively. All groups were evaluated at the end of 2 weeks and 6 weeks. When the pre-treatment and post-treatment parameters were compared between the groups, a decrease was determined in the parameters of pain, limitation of jaw function, and restriction of oral behavioursin Group1 and Group2 (p = 0.001, p = 0.05, respectively). This decrease was statistically greater in Group 1. No statistically significant difference was determined in Group 3 in respect of resting, active and night pain, limitation of jaw function and restriction of oral behaviour (p>0.05). Proprioceptive Neuromuscular Facilitation Exercises + myofascial releasing techniques + home exercise were found to be effective in reducing pain, improving restriction of jaw movement and oral behaviors in patients with bruxism. As the first such study, the results of this study can be considered to provide important contributions to the understanding and treatment of patients with bruxism. [Med-Science 2018; 7(3.000): 617-21

Die neuzeitliche Apotheke und ihre Kundenwerbung / Hrsg. Mitteldeutscher Pharmazie-Konzern e.V.

Bacterial Cellulose (BC) has over recent decades shown great versatility in wound healing dressings, but is difficult to spin fibers with at high concentrations. An investigation into the preparation of bandage-like fibrous meshes is carried out to determine the optimal blend of polycaprolactone (PCL) and polylactic acid (PLA) as a suitable carrier for BC. Using a simple centrifugal spinning setup, polymer blends of PCL, PLA and BC are investigated as a ternary system to determine the most suitable composition with a focus on achieving maximal BC concentration. It is found that BC content in the fibers above 10 wt % reduced product yield. By creating blends of PLA-PCL fibers, we can create a more suitable system in terms of yield and mechanical properties. The fibrous samples are examined for yield, fiber morphology using scanning electron microscopy, mechanical properties using tensile testing and chemical characteristics using Fourier-transform infrared spectroscopy. A fibrous scaffold with > 30 wt % BC was produced with enhanced mechanical properties owing to the blending of PLA and PCL