Audiographic-based instructional delivery

Issued as Quarterly report [1-3], and Final report, Project no. G-36-605Final report has title: Audiographic-based instructional delivery: an experiment in Georgia educatio

Analysis of the IBM-9000

Issued as Final report, Project no. G-36-60

Distributed combat service support advanced experimental demonstrations

Issued as Final report, Project no. G-36-61

Family planning regional data network

Issued as Implementation plan and schedule, Bimonthly progress summary [1-5], Network design, Preliminary assessment, and Final report, Project no. G-36-614Final report has title: System user's documentation for a family planning regional data networ

Chemical Variation In Lodgepole Pine With Sapwood/Heartwood, Stem Height, and Variety

The chemical variation in lodgepole pine over its geographical range with sapwood/heartwood, stem height, and variety was investigated. In both varieties, latifolia and murrayana, the heartwood was significantly higher in extractives than the sapwood, whereas the sapwood was significantly higher in holocellulose and alpha-cellulose than the heartwood. The sapwood and heartwood did not differ in pH and lignin content.Ash, lignin, and holocellulose content were positively correlated with stem height in latifolia and murrayana. Extractive and alpha-cellulose content were negatively correlated with stem height. The stem height variations appeared to be related to the heartwood/sapwood ratio, proportion of mature and juvenile wood, and the specific gravity.The variation between latifolia and murrayana in ash, extractive, and lignin content and pH was small. In contrast, the holocellulose and alpha-cellulose content was 2% higher in murrayana than in latifolia. The polysaccharide variation may be influenced by climate and site conditions as well as genetic differences

Comparison of reproducibility, accuracy, sensitivity, and specificity of miRNA quantification platforms

Given the increasing interest in their use as disease biomarkers, the establishment of reproducible, accurate, sensitive, and specific platforms for microRNA (miRNA) quantification in biofluids is of high priority. We compare four platforms for these characteristics: small RNA sequencing (RNA-seq), FirePlex, EdgeSeq, and nCounter. For a pool of synthetic miRNAs, coefficients of variation for technical replicates are lower for EdgeSeq (6.9%) and RNA-seq (8.2%) than for FirePlex (22.4%); nCounter replicates are not performed. Receiver operating characteristic analysis for distinguishing present versus absent miRNAs shows small RNA-seq (area under curve 0.99) is superior to EdgeSeq (0.97), nCounter (0.94), and FirePlex (0.81). Expected differences in expression of placenta-associated miRNAs in plasma from pregnant and non-pregnant women are observed with RNA-seq and EdgeSeq, but not FirePlex or nCounter. These results indicate that differences in performance among miRNA profiling platforms impact ability to detect biological differences among samples and thus their relative utility for research and clinical use

Greenland turbot Reinhardtius hippoglossoides of the eastern Bering Sea and Aleutian Islands region

Greenland turbot (Reinhardtius hippoglossoides) is a commercially important flounder in both the North Atlantic and North Pacific Oceans. In the latter, its center of abundance is in the eastern Bering Sea and along the Aleutian Islands chain where its population is managed as a single stock. Harvest levels in this region of the North Pacific during the period 1970-81 were comparable with those in the northwest and northeast Atlantic, with annual average catches of 53,000 metric tons (t). However, the catch in 1984 dropped sharply to 23,100 t, in part because of reduced quotas arising from concern over continued poor recruitment and declining catch-per-unit-effort. Recruitment failure was manifested in 1) the sharp decline in the catch rate of young flsh in annual research trawl surveys on the continental shelf of the eastern Bering Sea and 2) an increasing proportion of older and larger fish in the commercial catch from the continental slope of both the eastern Bering Sea and Aleutian Islands. The cause ofthe decline in recruitment could not be clearly identifled. Greenland turbot of the Bering Sea-Aleutian Islands share certain distributional features with the North Atlantic form. There is an apparent bathymetric change in the size and age of fish, with younger animals occupying continental shelf depths and the older individuals residing at depths of the continental slope. At shallow depths the young are exposed to temperature fluctuations, whereas older animals along the slope are exposed to relatively stable temperatures. A hypothesis is proposed for describing the temporal and spatial paths by which young animals reach the mature or spawning portion of the population. (PDF file contains 38 pages.

GALEX Observations of the Ultraviolet Halos of NGC 253 and M82

We present Galaxy Evolution Explorer (GALEX) images of the prototypical edge-on starburst galaxies M82 and NGC253. Our initial analysis is restricted to the complex of ultraviolet (UV) filaments in the starburst-driven outflows in the galaxy halos. The UV luminosities in the halo are too high to be provided by shock-heated or photoionized gas except perhaps in the brightest filaments in M82, suggesting that most of the UV light is the stellar continuum of the starburst scattered into our line of sight by dust in the outflow. This interpretation agrees with previous results from optical imaging polarimetry in M82. The morphology of the UV filaments in both galaxies shows a high degree of spatial correlation with H-alpha and X-ray emission. This indicates that these outflows contain cold gas and dust, some of which may be vented into the intergalactic medium (IGM). UV light is seen in the ``H-alpha cap'' 11 kpc North of M82. If this cap is a result of the wind fluid running into a pre-existing gas cloud, the gas cloud contains dust and is not primordial in nature but was probably stripped from M82 or M81. If starburst winds efficiently expel dust into the IGM, this could have significant consequences for the observation of cosmologically distant objects.Comment: This paper will be published as part of the Galaxy Evolution Explorer (GALEX) Astrophysical Journal Letters Special Issue. Links to the full set of papers will be available at http://www.galex.caltech.edu/PUBLICATIONS/ after November 22, 200