Uso del debate formal como herramienta de innovación docente para el desarrollo temprano de las habilidades de comunicación y el análisis crítico de los estudiantes de Ciencias de la Salud

Depto. de FisiologíaFac. de MedicinaFALSEsubmitte

Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial.

BACKGROUND: Remote ischaemic conditioning with transient ischaemia and reperfusion applied to the arm has been shown to reduce myocardial infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). We investigated whether remote ischaemic conditioning could reduce the incidence of cardiac death and hospitalisation for heart failure at 12 months. METHODS: We did an international investigator-initiated, prospective, single-blind, randomised controlled trial (CONDI-2/ERIC-PPCI) at 33 centres across the UK, Denmark, Spain, and Serbia. Patients (age >18 years) with suspected STEMI and who were eligible for PPCI were randomly allocated (1:1, stratified by centre with a permuted block method) to receive standard treatment (including a sham simulated remote ischaemic conditioning intervention at UK sites only) or remote ischaemic conditioning treatment (intermittent ischaemia and reperfusion applied to the arm through four cycles of 5-min inflation and 5-min deflation of an automated cuff device) before PPCI. Investigators responsible for data collection and outcome assessment were masked to treatment allocation. The primary combined endpoint was cardiac death or hospitalisation for heart failure at 12 months in the intention-to-treat population. This trial is registered with ClinicalTrials.gov (NCT02342522) and is completed. FINDINGS: Between Nov 6, 2013, and March 31, 2018, 5401 patients were randomly allocated to either the control group (n=2701) or the remote ischaemic conditioning group (n=2700). After exclusion of patients upon hospital arrival or loss to follow-up, 2569 patients in the control group and 2546 in the intervention group were included in the intention-to-treat analysis. At 12 months post-PPCI, the Kaplan-Meier-estimated frequencies of cardiac death or hospitalisation for heart failure (the primary endpoint) were 220 (8·6%) patients in the control group and 239 (9·4%) in the remote ischaemic conditioning group (hazard ratio 1·10 [95% CI 0·91-1·32], p=0·32 for intervention versus control). No important unexpected adverse events or side effects of remote ischaemic conditioning were observed. INTERPRETATION: Remote ischaemic conditioning does not improve clinical outcomes (cardiac death or hospitalisation for heart failure) at 12 months in patients with STEMI undergoing PPCI. FUNDING: British Heart Foundation, University College London Hospitals/University College London Biomedical Research Centre, Danish Innovation Foundation, Novo Nordisk Foundation, TrygFonden

Actividades para la enseñanza de inglés a través de contenidos en secundaria : (Curso PALE de Secundaria 2007, C.P.R. de Oviedo)

El Programa PALE (programa de apoyo al aprendizaje de lenguas extranjeras), cofinanciado por el Ministerio de Educación y Ciencia y las Comunidades Autónomas, pretende dar respuesta, desde el Sistema Educativo, a las necesidades derivadas de la mejora de la enseñanza y el aprendizaje de lenguas extranjeras en una sociedad como la actual, donde las lenguas se consideran conocimientos básicos que precisa la ciudadanía europea para su formación, para mejorar sus posibilidades de empleo, para la promoción del intercambio cultural y para la realización personal. Esta publicación es el fruto del grupo de trabajo constituido en la tercera fase del curso PALE 2007 para Secundaria del C.P.R. de Oviedo, tras la formación recibida en Asturias y en el extranjero. Se presentan una serie actividades para llevar a cabo en el aula a partir de los contenidos en Secundaria en las áreas de: Arte, Biología, Ciudadanía, Ciencias Sociales, Matemáticas, Música, Educación Física, Física y Química, y Tecnología. Las unidades trabajadas son respectivamente: Observation; Vertebrate animals; Human rights; 3-d shapes; Sound and its properties; Outdoor activities; Work and energy; Electricity; Technical materials. El libro está acompañado por 1 CD-ROM que muestra los contenidos en versión PDF y PowerPoint.AsturiasUniversidad de Oviedo. Facultad de Ciencias de la Educación; Calle Aniceto Sela s. n.; 33005 Oviedo; +34985103215; +34985103214;ES