6 research outputs found
The global retinoblastoma outcome study : a prospective, cluster-based analysis of 4064 patients from 149 countries
- Author
- Abdallah Elhassan
- Abdullahi Shehu U.
- Abdulqader Rula A.
- Abdulrahaman Aminatu A.
- Abouelnaga Sherif
- Ademola-Popoola Dupe S.
- Adio Adedayo
- Afifi Mahmoud A.
- Afshar Armin R.
- Aggarwal Priyanka
- Aghaji Ada E.
- Ahmad Alia
- Akib Indonesia Marliyanti N.R.
- Akinsete Adeseye
- Al Ani Mouroge H.
- Al Harby Lamis
- Al Mesfer Saleh
- Al-Badri Safaa A.F.
- Al-Dahmash Saad A.
- Al-Haddad Christiane E.
- Al-Hussaini Hamoud H.Y.
- Al-Jadiry Mazin F.
- Al-Janabi Allawi N. Hussein
- Al-Jumaily Usama
- Al-Mafrachi Ali A.R.M.
- Al-Shaheen Athar A.S.M.
- Al-Shammary Entissar H.
- Alcasabas Ana Patricia A.
- Aldana David Garcia
- Alejos Amanda
- Alemany-Rubio Ernesto
- Alfa Bio Amadou I.
- Ali Amany M.
- Alia Donjeta B.
- Alkatan Hind M.
- All-Eriksson Charlotta
- Almeida Argentino A.
- Alsawidi Khalifa M.
- Amankwaa-Frempong Doreen
- Amiruddin Primawita O.
- Anchaya Jacqueline Karina Vasquez
- Armytasari Inggar
- Astbury Nicholas J.
- Atalay Hatice T.
- Atchaneeyasakul La-ongsri
- Atsiaya Rose
- Autrata Rudolf
- Balaguer Julia
- Balayeva Ruhengiz
- Barranco Honorio
- Bartoszek Paulina
- Bartuma Katarina
- Bascaran Covadonga
- Bechrakis Nikolaos E.
- Begimkulova Ainura S.
- Benmiloud Sarra
- Berete Rokia C.
- Berry Jesse L.
- Bhaduri Anirban
- Bhat Sunil
- Bhattacharyya Arpita
- Biewald Eva M.
- Binkley Elaine
- Blum Sharon
- Bobrova Nadia
- Boldt H.C.
- Bonanomi Maria Teresa B.C.
- Bouda Gabrielle C.
- Bouguila Hedi
- Bowman Richard
- Bowman Richard
- Brennan Rachel C.
- Brichard Benedicte G.
- Buaboonnam Jassada
- Budiongo Aleine
- Burton Matthew J.
- Calderon-Sotelo Patricia
- Calvo Jesus Peralta
- Camuglia Jayne E.
- Cano Miriam R.
- Capra Michael
- Carreras Yvania Alfonso
- Caspi Shani
- Cassoux Nathalie
- Castela Guilherme
- Castillo Luis
- Catala-Mora Jaume
- Cavieres Isabel
- Chafla Edwin G. Villacis
- Chandramohan Arthika
- Chantada Guillermo L.
- Chantada Guillermo L.
- Chantada Guillermo L.
- Chaudhry Shabana
- Chawla Bhavna
- Chen Wensi
- Chiwanga Faraja S.
- Chuluunbat Tsengelmaa
- Cieslik Krzysztof
- Clark Antony
- Cockcroft Ruellyn L.
- Comsa Codruta
- Coronado Rosdali Y. Díaz
- Corson Timothy W.
- Couitchere Line
- Cowan-Lyn Kristin E.
- Csoka Monika
- Dangboon Wantanee
- Das Anirban
- Das Pranab
- Das Sima
- Davanzo Jacquelyn M.
- Davidson Alan
- De Francesco Sonia
- De Potter Patrick
- Demirci Hakan
- Desjardins Laurence
- Dimaras Helen
- Dod Charlotte Wolley
- Dodgshun Andrew J.
- Dragomir Monica D.
- Du Bruyn Magritha
- Du Plessis Johannes
- Du Yi
- Dudeja Gagan
- Eerme Katrin
- El Kettani Asmaa
- Elbahi Amal M.
- Elder James E.
- Elhaddad Alaa M.
- Elhassan Moawia M.A.
- Elzembely M.
- Ericksen Connor
- Essuman Vera A.
- Evina Ted Grimbert A.
- Ezegwui Ifeoma R.
- Fabian Ido Didi
- Fabian Ido Didi
- Fadoo Zehra
- Fandiño Adriana C.
- Faranoush Mohammad
- Fasina Oluyemi
- Fernandez Delia D.P.G.
- Fernandez-Teijeiro Ana
- Foster Allen
- Frenkel Shahar
- Fu Ligia D.
- Fuentes-Alabi Soad L.
- Garcia Juan L.
- Geel Jennifer A.
- Ghassemi Fariba
- Giron Ana V.
- Goenz Marco A.
- Gold Aaron S.
- Goldberg Hila
- Gomel Nir
- Gonzalez Efren
- Gonzalez-Rodriguez Liudmira
- Gopinathan Nair Akshay
- Gorfine Malka
- Graells Jaime
- Gregersen Pernille A.
- Grigorovski Nathalia D.A.K.
- Groznik Alenka Lavric
- Guedenon Koffi M.
- Gunasekera D. Sanjeeva
- Gupta Himika
- Gupta Sanjiv
- Gupta Vineeta
- Gündüz Ahmet K.
- Hadjistilianou Theodora
- Hamel Patrick
- Hamid Syed A.
- Hamzah Norhafizah
- Hansen Eric D.
- Harbour William
- Hartnett M. Elizabeth
- Hasanreisoglu Murat
- Hassan Muhammad
- Hassan Sadiq
- Hassan Shadab
- Hautz Wojciech
- Haydar Huda
- Hederova Stanislava
- Hessissen Laila
- Hongeng Suradej
- Hordofa Diriba F.
- Hubbard G. Baker
- Hummelen Marlies
- Husakova Kristina
- Ibanga Affiong
- Ida Russo
- Ilic Vesna R.
- Islamia Ispahani
- Islamov Ziyavuddin
- Jairaj Vivekaraj
- Jara Doris A. Calle
- Jeeva Irfan
- Ji Xunda
- Jo Dong Hyun
- Jones Michael M.
- Kabesha Amani Theophile B.
- Kabore Rolande L.
- Kaliki Swathi
- Kalinaki Abubakar
- Kamsang Pius
- Kapelushnik Noa
- Kardava Tamar
- Kebudi Rejin
- Keomisy Jonny
- Kepak Tomas
- Ketteler Petra
- Khan Zohora
- Khaqan Hussain A.
- Khetan Vikas
- Khodabande Alireza
- Khotenashvili Zaza
- Kim Jeong Hun
- Kim Jonathan W.
- Kiratli Hayyam
- Kivela Tero T.
- Klett Artur
- Kosh Komba Palet Jess Elio
- Ko~ Irem
- Krivaitiene Dalia
- Kruger Mariana
- Kulvichit Kittisak
- Kuntorini Mayasari W.
- Kyara Alice
- Lam Geoffrey C.
- Larson Scott A.
- Latinovic Slobodanka
- Laurenti Kelly D.
- Lavy Yotam
- Leiva Fanny F. Tarrillo
- Leverant Amy A.
- Li Cairui
- Li Kaijun
- Limbu Ben
- Liu Chun-Hsiu
- Llano Maria G. Correa
- Lopez Arturo M. Zapata
- Lopez Juan P.
- Lukamba Robert M.
- Luna-Fineman Sandra
- Lutfi Delfitri
- Lysytsia Lesia
- Macedo Carla R. Donato
- Madgar Shiran
- Magrath George N.
- Mahajan Amita
- Maitra Puja
- Maka Erika
- Makimbetov Emil K.
- Maktabi Azza
- Maldonado Carlos
- Mallipatna Ashwin
- Manudhane Rebecca
- Manzhuova Lyazat
- Martin-Begue Nieves
- Masud Sidra
- Matende Ibrahim O.
- Mattosinho Clarissa C.D.S.
- Matua Marchelo
- Mayet Ismail
- Mbumba Freddy B.
- McKenzie John D.
- Mehrvar Azim
- Mengesha Aemero A.
- Menon Vikas
- Mercado Gary John V.
- Mets Marilyn B.
- Midena Edoardo
- Midena Edoardo
- Miller Audra
- Mishra Divyansh K.C.
- Mndeme Furahini G.
- Mohamedani Ahmed A.
- Mohammad Mona T.
- Moll Annette C.
- Montero Margarita M.
- Morales Claudia R. Pascual
- Moreira Claude
- Mruthyunjaya Prithvi
- Msina Mchikirwa S.
- Msukwa Gerald
- Mudaliar Sangeeta S.
- Muma Kangwa I.M.
- Munier Francis L.
- Murray Timothy G.
- Musa Kareem O.
- Mushtaq Asma
- Musika Anne A.
- Mustak Hamzah
- Mustapha Tajudeen
- Muyen Okwen M.
- Myezo Khumo H.
- Naidu Gita
- Naidu Natasha
- Nair Akshay Gopinathan
- Natarajan Sundaram
- Naumenko Larisa
- Nency Yetty M.
- Neroev Vladimir
- Ng Yvonne
- Nikitovic Marina
- Nkanga Elizabeth D.
- Nkumbe Henry E.
- Numbi Marcel N.
- Nummi Kalle
- Nuruddin Murtuza
- Nyaywa Mutale
- Nyirenda Chinsisi
- Obono-Obiang Ghislaine
- Oliver Scott C .
- Oporto Joaquin
- Orozco Alma Janeth Sanchez
- Ortega-Hernández Miriam
- Oscar Alexander H.
- Ossandon Diego
- Pacheco Henry N. Garcia
- Pacheco Sonsoles San Roman
- Paintsil Vivian
- Paiva Luisa
- Palanivelu Mahesh Shanmugam
- Papyan Ruzanna
- Parrozzani Raffaele
- Paton Katherine E.
- Perez Graciela Gonzalez
- Peric Sanja
- Pe’er Jacob
- Pham Chau T.M.
- Philbert Remezo
- Plager David A.
- Pochop Pavel
- Polania Rodrigo A.
- Polyakov Vladimir
- Pompe Manca Tekavcic
- Ponce Jimena
- Popovic Maja Beck
- Portabella Silvia Alarcon
- Qadir Ali O.
- Qayyum Seema
- Qian Jiang
- Quah BoonLong
- Quintero D Karina
- Rahman Ardizal
- Rajkarnikar Purnima
- Ramanjulu Rajesh
- Ramasubramanian Aparna
- Ramirez-Ortiz Marco A.
- Randhawa Jasmeen K.
- Randrianarisoa Hoby Lalaina
- Raobela Lea
- Rashid Riffat
- Reddy M. Ashwin
- Refaeli David
- Renner Lorna A.
- Reynders David
- Ribadu Dahiru
- Ritter-Sovinz Petra
- Rogowska Anna
- Rojanaporn Duangnate
- Romero Livia
- Roth Paule Aida Ndoye
- Roy Soma R.
- Saab Raya H.
- Saakyan Svetlana
- Sabhan Ahmed H.
- Sagoo Mandeep S.
- Said Azza M.A.
- Saiju Rohit
- Salas Beatriz
- Sanchez Gissela L.
- Sayalith Phayvanh
- Scanlan Trish A.
- Schluter Sabrina
- Schwab Christoph
- Sedaghat Ahad
- Seth Rachna
- Sgroi Mariana
- Shah Ankoor S.
- Shakoor Shawkat A.
- Sharma Manoj K.
- Sherief Sadik T.
- Shields Carol L.
- Sia David
- Siddiqui Sorath Noorani
- Sidi cheikh Sidi
- Silva Sonia
- Singh Arun D.
- Singh Usha
- Singha Penny
- Sitorus Rita S.
- Skalet Alison H.
- Soebagjo Hendrian D.
- Sorochynska Tetyana
- Ssali Grace
- Stacey Andrew W.
- Staffieri Sandra E.
- Stahl Erin D.
- Steinberg David M.
- Stones David K.
- Strahlendorf Caron
- Suarez Maria Estela Coleoni
- Sultana Sadia
- Sun Xiantao
- Superstein Rosanne
- Supriyadi Eddy
- Surukrattanaskul Supawan
- Sutyawan I. Wayan Eka
- Suzuki Shigenobu
- Svojgr Karel
- Sylla Fatoumata
- Tamamyan Gevorg
- Tan Deborah
- Tandili Alketa
- Tang Jing
- Tashvighi Maryam
- Tateshi Bekim
- Teh Kok Hoi
- Tehuteru Edi S.
- Teixeira Luiz F.
- Thawaba Abdullah Dahan M.
- Theophile Tuyisabe
- Toledano Helen
- Trang Doan L.
- Traore Fousseyni
- Tripathy Devjyoti
- Tuncer Samuray
- Tyau-Tyau Harba
- Umar Ali B.
- Unal Emel
- Uner Ogul E.
- Urbak Steen F.
- Ushakova Tatiana L.
- Usmanov Rustam H.
- Valeina Sandra
- Valente Paola
- Van Hoefen Wijsard Milo
- Vaughan Leon O.
- Veleva-Krasteva Nevyana V.
- Verma Nishant
- Victor Andi A.
- Viksnins Maris
- Villegas Victor M.
- Vishnevskia-Dai Victoria
- Waddell Keith
- Wali Amina H.
- Wang Yi-Zhuo
- Wangtiraumnuay Nutsuchar
- Wetter Julie
- Widiarti Widiarti
- Wilson Matthew W.
- Wime Amelia D.C.
- Wiwatwongwana Atchareeya
- Wiwatwongwana Damrong
- Wong Emily S.
- Wongwai Phanthipha
- Wu Si-qi
- Xiang Daoman
- Xiao Yishuang
- Xu Bing
- Xue Kang
- Yaghy Antonio
- Yam Jason C.
- Yang Huasheng
- Yanga Jenny M.
- Yarovaya Vera A.
- Yarovoy Andrey A.
- Ye Huijing
- Yee Roberto I.
- Yousef Yacoub A.
- Yuliawati Putu
- Zein Ekhtelbenina
- Zhang Yi
- Zhilyaeva Katsiaryna
- Zia Nida
- Ziko Othman A.O.
- Zondervan Marcia
- Publication venue
- Elsevier
- Publication date
- 23/08/2022
- Field of study
DATA SHARING : The study data will become available online once all analyses are complete.BACKGROUND : Retinoblastoma is the most common intraocular cancer worldwide. There is some evidence to suggest that major differences exist in treatment outcomes for children with retinoblastoma from different regions, but these differences have not been assessed on a global scale. We aimed to report 3-year outcomes for children with retinoblastoma globally and to investigate factors associated with survival. METHODS : We did a prospective cluster-based analysis of treatment-naive patients with retinoblastoma who were diagnosed between Jan 1, 2017, and Dec 31, 2017, then treated and followed up for 3 years. Patients were recruited from 260 specialised treatment centres worldwide. Data were obtained from participating centres on primary and additional treatments, duration of follow-up, metastasis, eye globe salvage, and survival outcome. We analysed time to death and time to enucleation with Cox regression models. FINDINGS : The cohort included 4064 children from 149 countries. The median age at diagnosis was 23·2 months (IQR 11·0–36·5). Extraocular tumour spread (cT4 of the cTNMH classification) at diagnosis was reported in five (0·8%) of 636 children from high-income countries, 55 (5·4%) of 1027 children from upper-middle-income countries, 342 (19·7%) of 1738 children from lower-middle-income countries, and 196 (42·9%) of 457 children from low-income countries. Enucleation surgery was available for all children and intravenous chemotherapy was available for 4014 (98·8%) of 4064 children. The 3-year survival rate was 99·5% (95% CI 98·8–100·0) for children from high-income countries, 91·2% (89·5–93·0) for children from upper-middle-income countries, 80·3% (78·3–82·3) for children from lower-middle-income countries, and 57·3% (52·1-63·0) for children from low-income countries. On analysis, independent factors for worse survival were residence in low-income countries compared to high-income countries (hazard ratio 16·67; 95% CI 4·76–50·00), cT4 advanced tumour compared to cT1 (8·98; 4·44–18·18), and older age at diagnosis in children up to 3 years (1·38 per year; 1·23–1·56). For children aged 3–7 years, the mortality risk decreased slightly (p=0·0104 for the change in slope). INTERPRETATION : This study, estimated to include approximately half of all new retinoblastoma cases worldwide in 2017, shows profound inequity in survival of children depending on the national income level of their country of residence. In high-income countries, death from retinoblastoma is rare, whereas in low-income countries estimated 3-year survival is just over 50%. Although essential treatments are available in nearly all countries, early diagnosis and treatment in low-income countries are key to improving survival outcomes.The Queen Elizabeth Diamond Jubilee Trust and the Wellcome Trust.https://www.thelancet.com/journals/langlo/homeam2023Paediatrics and Child Healt
Clinical Characteristics of Individuals With Schizophrenia and Hallucinogen Persisting Perception Disorder: A Preliminary Investigation
- Author
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Treatment of autoinflammatory diseases: results from the Eurofever Registry and a literature review.
- Author
- Publication venue
- 'BMJ'
- Publication date
- 01/01/2013
- Field of study
Particle laden fluid interfaces: Dynamics and interfacial rheology
- Author
- Alexander
- Alexandrov
- Alma J. Mendoza
- Arriaga
- Bain
- Barentin
- Basavaraj
- Bellour
- Benjamins
- Bhattacharya
- Binks
- Binks
- Bonales
- Bonales
- Bonales
- Bresme
- Brooks
- Catapano
- Cervantes-Martinez
- Chen
- Choi
- Cicuta
- Cicuta
- Cicuta
- Cui
- Danov
- Danov
- Danov
- Dasgupta
- Degen
- Dhar
- Dhont
- Dimova
- Eduardo Guzmán
- Evans
- Felderhof
- Fernando Martínez-Pedrero
- Findley
- Fischer
- Fischer
- Francisco Ortega
- Frenkel
- Fuller
- Fuller
- Galvan-Miyoshi
- Gardel
- Grigoriev
- Guzmán
- Guzmán
- Guzmán
- Guzmán
- Guzmán
- Hasnain
- Hernán Ritacco
- Hiles
- Hiles
- Hilles
- Hilles
- Joos
- Keim
- Keim
- Kobayashi
- Konopka
- Kralchevsky
- Krall
- Krishnaswamy
- Krotov
- Krägel
- Krägel
- Langevin
- Law
- Lee
- Levine
- Liggieri
- Liggieri
- Liu
- Louit
- Lyklema
- Maas
- Madivala
- Madivala
- Maestro
- Maestro
- Maestro
- Maestro
- Maestro
- Maestro
- Mason
- Mason
- Masschaele
- Mazoyer
- Mazoyer
- Meinders
- Miller
- Miller
- Monroy
- Monroy
- Morse
- Moschakis
- Muñoz
- Ohshima
- Orsi
- Ortega
- Ou-Yang
- Pelipenki
- Peng
- Prasad
- Prasad
- Pusey
- Ramón G. Rubio
- Ravera
- Ravera
- Reinhard Miller
- Reynaert
- Reynaert
- Ritacco
- Romers
- Saffman
- Safouane
- Sagis
- Santini
- Santini
- Santini
- Santini
- Saxton
- Sickert
- Sickert
- Song
- Stocco
- Stone
- van den Tempel
- Vandebril
- Vandebril
- Verwijlen
- Victor M. Starov
- Vilaseca
- Volkov
- Wang
- Whitby
- Wu
- Wu
- Wu
- Wyss
- Yazhgur
- Zabiegaj
- Zang
- Zang
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part one
- Author
- A. Berman
- A. Cochino
- A. De Jesus
- A. Groll
- A. Insalaco
- A. Jansson
- A. Kazmirchyk
- A. Kozlova
- A. Lazar
- A. Martini
- A. Martini
- A. Martini
- A. Martini
- A. Martini
- A. Ombrello
- A. Pistorio
- A. Ravelli
- A. Simon
- A. Simon
- A. Simon
- A. Simon
- A. Speziale
- A. Speziale
- A. Speziale
- A. Speziale
- A. Speziale
- A. Zeft
- A. Zeft
- A. Zeft
- Abdullah Alsonbul
- Abdullah Calıskan
- Achille Marino
- Acute-JIA Study Group
- Adel Al-Wahadneh
- Adele Civino
- Adele D’Amico
- Adrian Liston
- Adriana Ivonne Cespedes-Cruz
- Adriana Rodriguez Vidal
- Adriana S. Díaz-Maldonado
- Agneza Marija Pasini
- Ahmet B. Cekgeloglu
- Ahmet Gul
- Aki Hanaya
- Akihiro Yachie
- Akihiro Yachie
- Akihiro Yachie
- Alain Fischer
- Alan Salama
- Alberto Garaventa
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Tommasini
- Alberto Tommasini
- Alberto Tommasini
- Alberto Vieira
- Aleksandra Czajkowska
- Aleksandra Szabat
- Aleksandre Kajrishvili
- Aleksandre Kajrishvili
- Aleksey Kozhevnikov
- Alena Torbyak
- Alenka Gagro
- Alessandra Meneghel
- Alessandra Russo
- Alessandro Cafarotti
- Alessandro Consolaro
- Alessandro Consolaro
- Alessandro De Fanti
- Alessandro Ventura
- Alessia Omenetti
- Alessia Omenetti
- Alessia Omenetti
- Alexandre Belot
- Alexandre Belot
- Alexandre Belot
- Alexandre Belot
- Alexey Maschan
- Alfonso Ragnar Torres-Jimenez
- Alfred Mahr
- Alice Grossi
- Alice Grossi
- Alma Nunzia Olivieri
- Alma Olivieri
- Almira Ćosićkić
- Amanda Ombrello
- Amanda Radulescu
- Amanda Saracino
- Amit Rawat
- Amit Rawat
- Amit Rawat
- Amra Adrovic
- Amra Adrovic
- Amra Adrovic
- Amra Adrovic
- Amra Adrovic
- Amra Adrovic
- An Goris
- Ana F. Mourão
- Ana M. Marín Sánchez
- Ana V. Villarreal
- Ana V. Villarreal Treviño
- Ana V. Villarreal-Treviño
- Ana Vieira
- Ana Villarreal
- Anders Fasth
- Andrea Magnolato
- Andrea Pession
- Andrea Petretto
- Andrea Taddio
- Andrea Taddio
- Andrea Taddio
- Andressa G. Alves
- Andressa G. Alves
- Andrew Henrey
- Angel J. Flores-Pineda
- Angela Aquilani
- Angela C. Mosquera
- Angela C. Mosquera
- Angela Cox
- Angela Mauro
- Angela Mauro
- Angela Mauro
- Angela McArdle
- Angela Miniaci
- Angela Pistorio
- Angela Pistorio
- Angela Rösen-Wolff
- Angelika Thon
- Angelo Ravelli
- Angelo Ravelli
- Angelo Ravelli
- Angelo Ravelli
- Angelo Ravelli
- Angelo Ravelli
- Angelo Ravelli
- Angelo Ravelli
- Anita Dhanrajani
- Anju Gupta
- Anju Gupta
- Anju Gupta
- Anju Gupta
- Anju Gupta
- Ankur Kumar
- Ankur Kumar
- Anna C. Schulz
- Anna Gruenpeter
- Anna Kozlova
- Anna Mondino
- Anna Pogodina
- Anna Rubartelli
- Anna Shcherbina
- Anna Simon
- Anna Vermé
- Annacarin Horne
- Annalisa Chiocchetti
- Annalisa Salis
- Anne Grethe Jurik
- Anne H. Spannow
- Anne Hinks
- Anne Hulin
- Anne Lohse
- Anne Pagnier
- Anne Thorwarth
- Anne-Laure Mathieu
- Anneleen Avau
- Annemarie van Nieuwenhuijze
- Annemieke S. Littooij
- Annette Jansson
- Annette Keylock
- Annette von Scheven-Gête
- Antje Nimtz-Talaska
- Anton Hospach
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Petaccia
- Antonella Petaccia
- Antonella Petaccia
- Antonia Kienast
- Antonio Fernández-Nebro
- Antonio L. Urda Cardona
- Antonio L. Urda Cardona
- Antonio Novelli
- Antonio Urda-Cardona
- Ariane Klein
- Ariane Standing
- Arinna Bertoni
- Arinna Bertoni
- Arinna Bertoni
- Arne Hørlyck
- Aygen Yılmaz
- Aysenur Pac Kısaarslan
- Aysenur Pac Kisaarslan
- Ayşen Bingöl
- Ayşenur Kısaarslan
- B. Flato
- B. Lauwerys
- B. Lauwerys
- Bahar Muezzinoglu
- Balahan Makay
- Balahan Makay
- Balahan Makay
- Banu Acar
- Banu Orak
- Barbara Stanimirovic
- Belinda Hernandez
- Belkisa Čolić
- Berenice Sanchez-Jara
- Berent Prakken
- Berent Prakken
- Beril Talim
- Berit Flato
- Berna E. Fidanci
- Berna Eren Fidanci
- Berta Lopez Montesinos
- Betul Sozeri
- Betul Sozeri
- Betul Sozeri
- Betül Sozeri
- Betül Sözeri
- Beverley Almeida
- Biagio Castaldi
- Bianca Lattanzi
- BIKER collaborative group
- Bilade Cherqaoui
- Biljana Djurdjevic-Banjac
- Biman Saikia
- Biman Saikia
- Birgitte T. Mahler
- Bita Arabshahi
- Bo Magnusson
- Bo Magnusson
- Board of the Swedish Pediatric Rheumatology Registry
- Bogumiła Szponar
- Boris Huegle
- Boris Hugle
- Brenden Dufault
- Brent Adler
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- Working Group “Juvenile Dermatomyositis” of the German Society for Paediatric and Adolescent Rheumatology (GKJR)
- X. Li
- X. Wei
- X. Xu
- Xiaomin Yu
- Y. Joubert
- Y. Joubert
- Y. Joubert
- Y. Joubert
- Y. Uziel
- Yanick Crow
- Yanick Crow
- Yanick Crow
- Yanick Crow
- Yanick J. Crow
- Yasar Karaaslan
- Yasin Bulut
- Yasuo Nakagishi
- Yasushi Kawaguchi
- Yavuz Tokgöz
- Yelda Bilginer
- Yelda Bilginer
- Yelda Bilginer
- Yelda Bilginer
- Yelda Bilginer
- Yiannis Ioannou
- Yiannis Ioannou
- Ying Hong
- Ying Hong
- Yoann Rose
- Yoann Rose
- Yonatan Butbul
- Yosef Uziel
- Yosef Uziel
- Yosef Uziel
- Yosef Uziel
- Yosuke Fujii
- Yukie Saito
- Yuksel Aliyazicioglu
- Yulia Kostina
- Yulia Kostina
- Yumi Tani
- Yunus Arıkan
- Yuridiana Ramirez
- Yuridiana Ramirez Loyola
- Yuridiana Ramírez
- Yvonne Kusche
- Z. Serap Arıcı
- Zehra Serap Arici
- Zelal Ekinci
- Zelal Ekinci
- Zelal Ekinci
- Zelal Ekinci Ekinci
- Zeno Sparchez
- Zeyad El-Habahbeh
- Zeynep Birsin Özçakar
- Zubeyde Gunduz
- Zubeyde Gunduz
- Zübeyde Gunduz
- Özge A. Gücenmez
- Özge Basaran
- Şebnem Sara Kılıc
- Publication venue
- place:236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
- Publication date
- 01/01/2017
- Field of study
The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries
- Author
- Abdallah Elhassan
- Abdullahi Shehu U.
- Abdulqader Rula A.
- Abdulrahaman Aminatu A.
- Abouelnaga Sherif
- Ademola-Popoola Dupe S.
- Adio Adedayo
- Afifi Mahmoud A.
- Afshar Armin R.
- Aggarwal Priyanka
- Aghaji Ada E.
- Ahmad Alia
- Akib Indonesia Marliyanti N. R.
- Akinsete Adeseye
- Al Ani Mouroge H.
- Al Harby Lamis
- Al Mesfer Saleh
- Al-Badri Safaa A. F.
- Al-Dahmash Saad A.
- Al-Haddad Christiane E.
- Al-Hussaini Hamoud Hy
- Al-Jadiry Mazin F.
- Al-Janabi Allawi N. Hussein
- Al-Jumaily Usama
- Al-Mafrachi Ali A. R. M.
- Al-Shaheen Athar A. S. M.
- Al-Shammary Entissar H.
- Alarcon Portabella Silvia
- Alcasabas Ana Patricia A.
- Alejos Amanda
- Alemany-Rubio Ernesto
- Ali Amany M.
- Alia Donjeta B.
- Alkatan Hind M.
- All-Eriksson Charlotta
- Almeida Argentino A.
- Alsawidi Khalifa M.
- Amani Theophile B. Kabesha
- Amankwaa-Frempong Doreen
- Amiruddin Primawita O.
- Armytasari Inggar
- Astbury Nicholas J.
- Atalay Hatice T.
- Ataseven Eda
- Atchaneeyasakul La-ongsri
- Atsiaya Rose
- Autrata Rudolf
- Balaguer Julia
- Balayeva Ruhengiz
- Barranco Honorio
- Bartoszek Paulina
- Bartuma Katarina
- Bascaran Covadonga
- Bechrakis Nikolaos E.
- Begimkulova Ainura S.
- Benmiloud Sarra
- Berete Rokia C.
- Berry Jesse L.
- Bhaduri Anirban
- Bhat Sunil
- Bhattacharyya Arpita
- Biewald Eva M.
- Binkley Elaine
- Bio Amadou I. Alfa
- Blum Sharon
- Bobrova Nadia
- Boldt H. C.
- Bonanomi Maria Teresa B. C.
- Bouda Gabrielle C.
- Bouguila Hedi
- Bowman Richard
- Brennan Rachel C.
- Brichard Benedicte G.
- Buaboonnam Jassada
- Budiongo Aleine
- Burton Matthew J.
- Calderon-Sotelo Patricia
- Calle Jara Doris A.
- Camuglia Jayne E.
- Cano Miriam R.
- Capra Michael
- Carreras Yvania Alfonso
- Caspi Shani
- Cassoux Nathalie
- Castela Guilherme
- Castillo Luis
- Catala-Mora Jaume
- Cavieres Isabel
- Chandramohan Arthika
- Chantada Guillermo L.
- Chaudhry Shabana
- Chawla Bhavna
- Cheikh Sidi Sidi
- Chen Wensi
- Chiwanga Faraja S.
- Chuluunbat Tsengelmaa
- Cieslik Krzysztof
- Clark Antony
- Cockcroft Ruellyn L.
- Coleoni Suarez Maria Estela
- Comsa Codruta
- Correa Llano Maria G.
- Corson Timothy W.
- Couitchere Line
- Cowan-Lyn Kristin E.
- Csoka Monika
- Dangboon Wantanee
- Das Anirban
- Das Pranab
- Das Sima
- Davanzo Jacquelyn M.
- Davidson Alan
- De Francesco Sonia
- De Potter Patrick
- Demirci Hakan
- Desjardins Laurence
- Diaz Coronado Rosdali Y.
- Dimaras Helen
- Dodgshun Andrew J.
- Donato Macedo Carla R.
- Dragomir Monica D.
- Du Bruyn Magritha
- Du Plessis Johannes
- Du Yi
- Dudeja Gagan
- Eerme Katrin
- El Kettani Asmaa
- Elbahi Amal M.
- Elder James E.
- Elhaddad Alaa M.
- Elhassan Moawia M. A.
- Elzembely M.
- Ericksen Connor
- Essuman Vera A.
- Evina Ted Grimbert A.
- Ezegwui Ifeoma R.
- Fabian Ido Didi
- Fadoo Zehra
- Fandino Adriana C.
- Faranoush Mohammad
- Fasina Oluyemi
- Fernandez Delia D. P. G.
- Fernandez-Teijeiro Ana
- Foster Allen
- Frenkel Shahar
- Fu Ligia D.
- Fuentes-Alabi Soad L.
- Garcia Aldana David
- Garcia Pacheco Henry N.
- Garcia Juan L.
- Geel Jennifer A.
- Ghassemi Fariba
- Giron Ana, V
- Goenz Marco A.
- Gold Aaron S.
- Goldberg Hila
- Gole Glen A.
- Gomel Nir
- Gonzalez Efren
- Gonzalez-Rodriguez Liudmira
- Gorfine Malka
- Graells Jaime
- Gregersen Pernille A.
- Grigorovski Nathalia D. A. K.
- Groznik Alenka Lavric
- Guedenon Koffi M.
- Gunasekera D. Sanjeeva
- Gunduz Ahmet K.
- Gupta Himika
- Gupta Sanjiv
- Gupta Vineeta
- Hadjistilianou Theodora
- Hamel Patrick
- Hamid Syed A.
- Hamzah Norhafizah
- Hansen Eric D.
- Harbour J. William
- Hartnett M. Elizabeth
- Hasanreisoglu Murat
- Hassan Muhammad
- Hassan Sadiq
- Hassan Shadab
- Hautz Wojciech
- Haydar Huda
- Hederova Stanislava
- Hessissen Laila
- Hongeng Suradej
- Hordofa Diriba F.
- Hubbard G. Baker
- Hummelen Marlies
- Husakova Kristina
- Ibanga Affiong
- Ida Russo
- Ilic Vesna R.
- Islamov Ziyavuddin
- Jairaj Vivekaraj
- Janjua Teyyeb
- Jeeva Irfan
- Ji Xunda
- Jo Dong Hyun
- Jones Michael M.
- Kabore Rolande L.
- Kaliki Swathi
- Kalinaki Abubakar
- Kamsang Pius
- Kantar Mehmet
- Kapelushnik Noa
- Kardava Tamar
- Kebudi Rejin
- Keomisy Jonny
- Kepak Tomas
- Ketteler Petra
- Khan Zohora
- Khaqan Hussain A.
- Khetan Vikas
- Khodabande Alireza
- Khotenashvili Zaza
- Kim Jeong Hun
- Kim Jonathan W.
- Kiratli Hayyam
- Kivela Tero T.
- Klett Artur
- Koc Irem
- Krivaitiene Dalia
- Kruger Mariana
- Kulvichit Kittisak
- Kuntorini Mayasari W.
- Kyara Alice
- Lam Geoffrey C.
- Larson Scott A.
- Latinovic Slobodanka
- Laurenti Kelly D.
- Lavy Yotam
- Leverant Amy A.
- Li Cairui
- Li Kaijun
- Limbu Ben
- Liu Chun-Hsiu
- Lopez Juan P.
- Lukamba Robert M.
- Luna-Fineman Sandra
- Lutfi Delfitri
- Lysytsia Lesia
- Madgar Shiran
- Magrath George N.
- Mahajan Amita
- Maitra Puja
- Maka Erika
- Makimbetov Emil K.
- Maktabi Azza
- Maldonado Carlos
- Mallipatna Ashwin
- Manudhane Rebecca
- Manzhuova Lyazat
- Martin-Begue Nieves
- Masud Sidra
- Matende Ibrahim O.
- Mattosinho Clarissa C. D. S.
- Matua Marchelo
- Mayet Ismail
- Mbumba Freddy B.
- McKenzie John D.
- Mehrvar Azim
- Mengesha Aemero A.
- Menon Vikas
- Mercado Gary John, V
- Mets Marilyn B.
- Midena Edoardo
- Miller Audra
- Mishra Divyansh K. C.
- Mndeme Furahini G.
- Mohamedani Ahmed A.
- Mohammad Mona T.
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- Montero Margarita M.
- Moreira Claude
- Mruthyunjaya Prithvi
- Msina Mchikirwa S.
- Msukwa Gerald
- Mudaliar Sangeeta S.
- Muma Kangwa I. M.
- Munier Francis L.
- Murray Timothy G.
- Musa Kareem O.
- Mushtaq Asma
- Musika Anne A.
- Mustak Hamzah
- Mustapha Tajudeen
- Muyen Okwen M.
- Myezo Khumo H.
- Naidu Gita
- Naidu Natasha
- Nair Akshay Gopinathan
- Natarajan Sundaram
- Naumenko Larisa
- Nency Yetty M.
- Neroev Vladimir
- Ng Yvonne
- Nikitovic Marina
- Nkanga Elizabeth D.
- Nkumbe Henry E.
- Numbi Marcel N.
- Nummi Kalle
- Nuruddin Murtuza
- Nyaywa Mutale
- Nyirenda Chinsisi
- Obono-Obiang Ghislaine
- Oliver Scott Cn
- Oporto Joaquin
- Ortega-Hernandez Miriam
- Oscar Alexander H.
- Ossandon Diego
- Pagarra Halimah
- Paintsil Vivian
- Paiva Luisa
- Palanivelu Mahesh Shanmugam
- Palet Jess Elio Kosh Komba
- Papyan Ruzanna
- Parrozzani Raffaele
- Pascual Morales Claudia R.
- Paton Katherine E.
- Pe&apos
- Peralta Calvo Jesus
- Perez Graciela Gonzalez
- Peric Sanja
- Pham Chau T. M.
- Philbert Remezo
- Plager David A.
- Pochop Pavel
- Polania Rodrigo A.
- Polyakov Vladimir
- Pompe Manca Tekavcic
- Ponce Jimena
- Popovic Maja Beck
- Qadir Ali O.
- Qayyum Seema
- Qian Jiang
- Quah BoonLong
- Quintero D Karina
- Rahman Ardizal
- Rajkarnikar Purnima
- Ramanjulu Rajesh
- Ramasubramanian Aparna
- Ramirez-Ortiz Marco A.
- Randhawa Jasmeen K.
- Randrianarisoa Hoby Lalaina
- Raobela Lea
- Rashid Riffat
- Reddy M. Ashwin
- Refaeli David
- Renner Lorna A.
- Reynders David
- Ribadu Dahiru
- Ritter-Sovinz Petra
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- Rojanaporn Duangnate
- Romero Livia
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- Roy Soma R.
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- Saakyan Svetlana
- Sabhan Ahmed H.
- Sagoo Mandeep S.
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- Saiju Rohit
- Salas Beatriz
- San Roman Pacheco Sonsoles
- Sanchez Orozco Alma Janeth
- Sanchez Gissela L.
- Sayalith Phayvanh
- Scanlan Trish A.
- Schlueter Sabrina
- Schwab Christoph
- Sedaghat Ahad
- Seth Rachna
- Sgroi Mariana
- Shah Ankoor S.
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- Sherief Sadik T.
- Shields Carol L.
- Sia David
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- Singh Usha
- Singha Penny
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- Skalet Alison H.
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- Sorochynska Tetyana
- Ssali Grace
- Stacey Andrew W.
- Staffieri Sandra E.
- Stahl Erin D.
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- Stones David K.
- Strahlendorf Caron
- Sultana Sadia
- Sun Xiantao
- Superstein Rosanne
- Supriyadi Eddy
- Surukrattanaskul Supawan
- Sutyawan I. Wayan Eka
- Suzuki Shigenobu
- Svojgr Karel
- Sylla Fatoumata
- Tamamyan Gevorg
- Tan Deborah
- Tandili Alketa
- Tang Jing
- Tarrillo Leiva Fanny F.
- Tashvighi Maryam
- Tateshi Bekim
- Teh Kok Hoi
- Tehuteru Edi S.
- Teixeira Luiz F.
- Thawaba Abdullah Dahan M.
- Theophile Tuyisabe
- Toledano Helen
- Trang Doan L.
- Traore Fousseyni
- Tripathy Devjyoti
- Tuncer Samuray
- Tyau-Tyau Harba
- Umar Ali B.
- Unal Emel
- Uner Ogul E.
- Urbak Steen F.
- Ushakova Tatiana L.
- Usmanov Rustam H.
- Valeina Sandra
- Valente Paola
- Vasquez Anchaya Jacqueline Karina
- Vaughan Leon O.
- Veleva-Krasteva Nevyana V.
- Verma Nishant
- Victor Andi A.
- Viksnins Maris
- Villacis Chafla Edwin G.
- Villegas Victor M.
- Vishnevskia-Dai Victoria
- Waddell Keith
- Wali Amina H.
- Wang Yi-Zhuo
- Wangtiraumnuay Nutsuchar
- Wetter Julie
- Widiarti Widiarti
- Wijsard Milo van Hoefen
- Wilson Matthew W.
- Wime Amelia Dc
- Wiwatwongwana Atchareeya
- Wiwatwongwana Damrong
- Wolley Dod Charlotte
- Wong Emily S.
- Wongwai Phanthipha
- Wu Si-qi
- Xiang Daoman
- Xiao Yishuang
- Xu Bing
- Xue Kang
- Yaghy Antonio
- Yam Jason C.
- Yang Huasheng
- Yanga Jenny M.
- Yaqub Muhammad A.
- Yarovaya Vera A.
- Yarovoy Andrey A.
- Ye Huijing
- Yee Roberto, I
- Yousef Yacoub A.
- Yuliawati Putu
- Zapata Lopez Arturo M.
- Zein Ekhtelbenina
- Zhang Yi
- Zhilyaeva Katsiaryna
- Zia Nida
- Ziko Othman A. O.
- Zondervan Marcia
- Publication venue
- Elsevier BV
- Publication date
- 01/08/2022
- Field of study
Background Retinoblastoma is the most common intraocular cancer worldwide. There is some evidence to suggest that major differences exist in treatment outcomes for children with retinoblastoma from different regions, but these differences have not been assessed on a global scale. We aimed to report 3-year outcomes for children with retinoblastoma globally and to investigate factors associated with survival. Methods We did a prospective cluster-based analysis of treatment-naive patients with retinoblastoma who were diagnosed between Jan 1,2017, and Dec 31,2017, then treated and followed up for 3 years. Patients were recruited from 260 specialised treatment centres worldwide. Data were obtained from participating centres on primary and additional treatments, duration of follow-up, metastasis, eye globe salvage, and survival outcome. We analysed time to death and time to enucleation with Cox regression models. Findings The cohort included 4064 children from 149 countries. The median age at diagnosis was 23.2 months (IQR 11.0-36.5). Extraocular tumour spread (cT4 of the cTNMH classification) at diagnosis was reported in five (0.8%) of 636 children from high-income countries, 55 (5.4%) of 1027 children from upper-middle-income countries, 342 (19. 7%) of 1738 children from lower-middle-income countries, and 196 (42.9%) of 457 children from low-income countries. Enudeation surgery was available for all children and intravenous chemotherapy was available for 4014 (98.8%) of 4064 children. The 3-year survival rate was 99.5% (95% CI 98.8-100.0) for children from high-income countries, 91.2% (89.5-93.0) for children from upper-middle-income countries, 80.3% (78.3-82.3) for children from lower-middle-income countries, and 57.3% (524-63-0) for children from low-income countries. On analysis, independent factors for worse survival were residence in low-income countries compared to high-income countries (hazard ratio 16.67; 95% CI 4.76-50.00), cT4 advanced tumour compared to cT1 (8.98; 4.44-18.18), and older age at diagnosis in children up to 3 years (1.38 per year; 1.23-1.56). For children aged 3-7 years, the mortality risk decreased slightly (p=0.0104 for the change in slope). Interpretation This study, estimated to include approximately half of all new retinoblastoma cases worldwide in 2017, shows profound inequity in survival of children depending on the national income level of their country of residence. In high-income countries, death from retinoblastoma is rare, whereas in low-income countries estimated 3-year survival is just over 50%. Although essential treatments are available in nearly all countries, early diagnosis and treatment in low-income countries are key to improving survival outcomes. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd.Y