609 research outputs found
Strain evolution in GaN Nanowires: from free-surface objects to coalesced templates
Top-down fabricated GaN nanowires, 250 nm in diameter and with various
heights, have been used to experimentally determine the evolution of strain
along the vertical direction of 1-dimensional objects. X-ray diffraction and
photoluminescence techniques have been used to obtain the strain profile inside
the nanowires from their base to their top facet for both initial compressive
and tensile strains. The relaxation behaviors derived from optical and
structural characterizations perfectly match the numerical results of
calculations based on a continuous media approach. By monitoring the elastic
relaxation enabled by the lateral free-surfaces, the height from which the
nanowires can be considered strain-free has been estimated. Based on this
result, NWs sufficiently high to be strain-free have been coalesced to form a
continuous GaN layer. X-ray diffraction, photoluminescence and
cathodoluminescence clearly show that despite the initial strain-free nanowires
template, the final GaN layer is strained
"Endomicrobia" and Other Bacteria Associated with the Hindgut of Dermolepida albohirtum Larvae
Symbiotic bacteria residing in the hindgut chambers of scarab beetle larvae may be useful in paratransgenic approaches to reduce larval root-feeding activities on agricultural crops. We compared the bacterial community profiles associated with the hindgut walls of individual Dermolepida albohirtum third-instar larvae over 2 years and those associated with their plant root food source among different geographic regions. Denaturing gradient gel electrophoresis analysis was used with universal and Actinobacteria-specific 16S rRNA primers to reveal a number of taxa that were found consistently in all D. albohirtum larvae but not in samples from their food source, sugarcane roots. These taxa included representatives from the "Endomicrobia," Firmicutes, Proteobacteria, and Actinobacteria and were related to previously described bacteria from the intestines of other scarab larvae and termites. These universally distributed taxa have the potential to form vertically transmitted symbiotic associations with these insects
Delivering computationally-intensive digital patient applications to the clinic: An exemplar solution to predict femoral bone strength from CT data
Background and objective:Whilst fragility hip fractures commonly affect elderly people, often causing permanent disability or death, they are rarely addressed in advance through preventive techniques. Quantification of bone strength can help to identify subjects at risk, thus reducing the incidence of fractures in the population. In recent years, researchers have shown that finite element models (FEMs) of the hip joint, derived from computed tomography (CT) images, can predict bone strength more accurately than other techniques currently used in the clinic. The specialised hardware and trained personnel required to perform such analyses, however, limits the widespread adoption of FEMs in clinical contexts. In this manuscript we present CT2S (Computed Tomography To Strength), a system developed in collaboration between The University of Sheffield and Sheffield Teaching Hospitals, designed to streamline access to this complex workflow for clinical end-users. Methods:The system relies on XNAT and makes use of custom apps based on open source software. Available through a website, it allows doctors in the healthcare environment to benefit from FE based bone strength estimation without being exposed to the technical aspects, which are concealed behind a user-friendly interface. Clinicians request the analysis of CT scans of a patient through the website. Using XNAT functionality, the anonymised images are automatically transferred to the University research facility, where an operator processes them and estimates the bone strength through FEM using a combination of open source and commercial software. Following the analysis, the doctor is provided with the results in a structured report. Results:The platform, currently available for research purposes, has been deployed and fully tested in Sheffield, UK. The entire analysis requires processing times ranging from 3.5 to 8 h, depending on the available computational power. Conclusions:The short processing time makes the system compatible with current clinical workflows. The use of open source software and the accurate description of the workflow given here facilitates the deployment in other centres
The Interaction between the ISM and Star Formation in the Dwarf Starburst Galaxy NGC 4214
We present the first interferometric study of the molecular gas in the
metal-poor dwarf starburst galaxy NGC 4214. Our map of the 12CO(1-0) emission,
obtained at the OVRO millimeter array, reveals an unexpected structural wealth.
We detected three regions of molecular emission in the north-west (NW),
south-east (SE) and centre of NGC 4214 which are in very different and distinct
evolutionary stages (total molecular mass: 5.1 x 10^6 M_sun). These differences
are apparent most dramatically when the CO morphologies are compared to optical
ground based and HST imaging: massive star formation has not started yet in the
NW region; the well-known starburst in the centre is the most evolved and star
formation in the SE complex started more recently. We derive a star formation
efficiency of 8% for the SE complex. Using high--resolution VLA observations of
neutral hydrogen HI and our CO data we generated a total gas column density map
for NGC 4214 (HI + H_2). No clear correlation is seen between the peaks of HI,
CO and the sites of ongoing star formation. This emphasizes the irregular
nature of dwarf galaxies. The HI and CO velocities agree well, so do the
H-alpha velocities. In total, we cataloged 14 molecular clumps in NGC 4214. Our
results from a virial mass analysis are compatible with a Galactic CO-to-H_2
conversion factor for NGC 4214 (lower than what is usually found in metal-poor
dwarf galaxies).Comment: accepted for publication in the AJ (February 2001), full ps file at:
ftp://ftp.astro.caltech.edu/users/fw/ngc4214/walter_prep.p
Reflectionless tunneling in ballistic normal-metal--superconductor junctions
We investigate the phenomenon of reflectionless tunneling in ballistic
normal-metal--superconductor (NS) structures, using a semiclassical formalism.
It is shown that applied magnetic field and superconducting phase difference
both impair the constructive interference leading to this effect, but in a
qualitatively different way. This is manifested both in the conductance and in
the shot noise properties of the system considered. Unlike diffusive systems,
the features of the conductance are sharp, and enable fine spatial control of
the current, as well as single channel manipulations. We discuss the
possibility of conducting experiments in ballistic semiconductor-superconductor
structures with smooth interfaces and some of the phenomena, specific to such
structures, that could be measured. A general criterion for the barrier at NS
interfaces, though large, to be effectively transparent to pair current is
obtained.Comment: published versio
A fourâcomponent classification of uncertainties in biological invasions: implications for management
Although uncertainty is an integral part of any science, it raises doubts in public perception about scientific evidence, is exploited by denialists, and therefore potentially hinders the implementation of management actions. As a relatively young field of study, invasion science contains many uncertainties. This may explain why, despite international policies aimed at mitigating biological invasions, the implementation of national- and regional-scale measures to prevent or control alien species has done little to slow the increase in extent of invasions and the magnitude of impacts. Uncertainty is therefore a critical aspect of invasion science that should be addressed to enable the field to progress further. To improve how uncertainties in invasion science are captured and characterized, we propose a framework, which is also applicable to other applied research fields such as climate and conservation science, divided into four components: the need (1) to clearly circumscribe the phenomenon, (2) to measure and provide evidence for the phenomenon (i.e., confirmation), (3) to understand the mechanisms that cause the phenomenon, and (4) to understand the mechanisms through which the phenomenon results in consequences. We link these issues to three major types of uncertainty: linguistic, psychological, and epistemic. The application of this framework shows that the four components tend to be characterized by different types of uncertainty in invasion science.We explain how these uncertainties can be detrimental to the implementation of management measures and propose ways to reduce them. Since biological invasions are increasingly tightly embedded in complex socio-ecological systems, many problems associated with these uncertainties have convoluted solutions. They demand the consensus of many stakeholders to define and frame the dimensions of the phenomenon, and to decide on appropriate actions. While many of the uncertainties cannot be eliminated completely, we believe that using this framework to explicitly identify and communicate them will help to improve collaboration between researchers and managers, increase scientific, political, and public support for invasion research, and provide a stronger foundation for sustainable management strategies
Phase coherent transport in hybrid superconducting structures: the case of d-wave superconductors
We examine the effect of d-wave symmetry on zero bias anomalies in
normal-superconducting tunnel junctions and phase-periodic conductances in
Andreev interferometers. In the presence of d-wave pairing, zero-bias anomalies
are suppressed compared with the s-wave case. For Andreev interferometers with
aligned islands, the phase-periodic conductance is insensistive to the nature
of the pairing, whereas for non-aligned islands, the nature of the zero-phase
extremum is reversed.Comment: 10 Pages, Revtex. 11 postscript figures available on reques
The prevalence and incidence of mental ill-health in adults with autism and intellectual disabilities
The prevalence, and incidence, of mental ill-health in adults with intellectual disabilities and autism were compared with the whole population with intellectual disabilities, and with controls, matched individually for age, gender, ability-level, and Down syndrome. Although the adults with autism had a higher point prevalence of problem behaviours compared with the whole adult population with intellectual disabilities, compared with individually matched controls there was no difference in prevalence, or incidence of either problem behaviours or other mental ill-health. Adults with autism who had problem behaviours were less likely to recover over a two-year period than were their matched controls. Apparent differences in rates of mental ill-health are accounted for by factors other than autism, including Down syndrome and ability level
HST/WFPC2 and VLA Observations of the Ionized Gas in the Dwarf Starburst Galaxy NGC 4214
We present new H alpha and [O III] 5007 narrow band images of the
starbursting dwarf galaxy NGC 4214, obtained with the WFPC2 onboard HST,
together with VLA observations of the same galaxy. The HST images resolve
features down to physical scales of 2-5 pc, revealing several young (<10 Myr)
star forming complexes of various ionized gas morphologies (compact knots,
complete or fragmentary shells) and sizes (10-200 pc). Our results are
consistent with a uniform set of evolutionary trends: The youngest, smaller,
filled regions that presumably are those just emerging from dense star forming
clouds, tend to be of high excitation and are highly obscured. Evolved, larger
shell-like regions have lower excitation and are less extincted due of the
action of stellar winds and supernovae. In at least one case we find evidence
for induced star formation which has led to a two-stage starburst. Age
estimates based on W(H alpha) measurements do not agree with those inferred
from wind-driven shell models of expanding H II regions. The most likely
explanation for this effect is the existence of a 2 Myr delay in the formation
of superbubbles caused by the pressure exerted by the high density medium in
which massive stars are born. We report the detection of a supernova remnant
embedded in one of the two large H II complexes of NGC 4214. The dust in NGC
4214 is not located in a foreground screen but is physically associated with
the warm ionized gas.Comment: 41 pages, including 9 figures and 7 tables. To appear in the November
issue of the Astronomical Journa
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