622 research outputs found

    On the complete analytic structure of the massive gravitino propagator in four-dimensional de Sitter space

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    With the help of the general theory of the Heun equation, this paper completes previous work by the authors and other groups on the explicit representation of the massive gravitino propagator in four-dimensional de Sitter space. As a result of our original contribution, all weight functions which multiply the geometric invariants in the gravitino propagator are expressed through Heun functions, and the resulting plots are displayed and discussed after resorting to a suitable truncation in the series expansion of the Heun function. It turns out that there exist two ranges of values of the independent variable in which the weight functions can be divided into dominating and sub-dominating family.Comment: 21 pages, 9 figures. The presentation has been further improve

    Propagators for p-forms in AdS_{2p+1} and correlation functions in the AdS_7/(2,0) CFT correspondence

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    In AdS_{2p+1} we construct propagators for p-forms whose lagrangians contain terms of the form A / d A. In particular we explore the case of forms satisfying ``self duality in odd dimensions'', and the case of forms with a topological mass term. We point out that the ``complete'' set of maximally symmetric bitensors previously used in all the other propagator papers is incomplete - there exists another bitensor which can and does appear in the formulas for the propagators in this particular case. Nevertheless, its presence does not affect the other propagators computed so far. On the AdS side of the correspondence we compute the 2 and 3 point functions involving the self-dual tensor of the maximal 7d gauged supergravity (sugra), S_{\mu\nu\rho}. Since the 7 dimensional antisymmetric self-dual tensor obeys first order field equations (S + * d S=0), to get a nonvanishing 2 point function we add a certain boundary term (to satisfy the variational principle on a manifold with boundary) to the 7d action. The 3 point functions we compute are of the type SSB and SBB, describing vertex interactions with the gauge fields B_{\mu}.Comment: 21 pages, Latex file, one reference adde

    eIF4E3 forms an active eIF4F complex during stresses (eIF4FS) targeting mTOR and re-programs the translatome.

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    The eIF4E are a family of initiation factors that bind the mRNA 5' cap, regulating the proteome and the cellular phenotype. eIF4E1 mediates global translation and its activity is controlled via the PI3K/AKT/mTOR pathway. mTOR down-regulation results in eIF4E1 sequestration into an inactive complex with the 4E binding proteins (4EBPs). The second member, eIF4E2, regulates the translatome during hypoxia. However, the exact function of the third member, eIF4E3, has remained elusive. We have dissected its function using a range of techniques. Starting from the observation that it does not interact with 4EBP1, we demonstrate that eIF4E3 recruitment into an eIF4F complex occurs when Torin1 inhibits the mTOR pathway. Ribo-seq studies demonstrate that this complex (eIF4FS) is translationally active during stress and that it selects specific mRNA populations based on 5' TL (UTR) length. The interactome reveals that it associates with cellular proteins beyond the cognate initiation factors, suggesting that it may have 'moon-lighting' functions. Finally, we provide evidence that cellular metabolism is altered in an eIF4E3 KO background but only upon Torin1 treatment. We propose that eIF4E3 acts as a second branch of the integrated stress response, re-programming the translatome to promote 'stress resistance' and adaptation

    Ewald method for polytropic potentials in arbitrary dimensionality

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    The Ewald summation technique is generalised to power-law 1/|r|^k potentials in three-, two- and one-dimensional geometries with explicit formulae for all the components of the sums. The cases of short-range, long-range and "marginal" interactions are treated separately. The jellium model, as a particular case of a charge-neutral system, is discussed and the explicit forms of the Ewald sums for such system are presented. A generalised form of the Ewald sums for a noncubic (nonsquare) simulation cell for three- (two-) dimensional geometry is obtained and its possible field of application is discussed. A procedure for the optimisation of the involved parameters in actual simulations is developed and an example of its application is presented.Comment: 41 pages, 3 figure

    The variation in the eating quality of beef from different sexes and breed classes cannot be completely explained by carcass measurements

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    Delivering beef of consistent quality to the consumer is vital for consumer satisfaction and will help to ensure demand and therefore profitability within the beef industry. In Australia, this is being tackled with Meat Standards Australia (MSA), which uses carcass traits and processing factors to deliver an individual eating quality guarantee to the consumer for 135 different ‘cut by cooking methods’ from each carcass. The carcass traits used in the MSA model, such as ossification score, carcass weight and marbling explain the majority of the differences between breeds and sexes. Therefore, it was expected that the model would predict with eating quality of bulls and dairy breeds with good accuracy. In total, 8128 muscle samples from 482 carcasses from France, Poland, Ireland and Northern Ireland were MSA graded at slaughter then evaluated for tenderness, juiciness, flavour liking and overall liking by untrained consumers, according to MSA protocols. The scores were weighted (0.3, 0.1, 0.3, 0.3) and combined to form a global eating quality (meat quality (MQ4)) score. The carcasses were grouped into one of the three breed categories: beef breeds, dairy breeds and crosses. The difference between the actual and the MSA-predicted MQ4 scores were analysed using a linear mixed effects model including fixed effects for carcass hang method, cook type, muscle type, sex, country, breed category and postmortem ageing period, and random terms for animal identification, consumer country and kill group. Bulls had lower MQ4 scores than steers and females and were predicted less accurately by the MSA model. Beef breeds had lower eating quality scores than dairy breeds and crosses for five out of the 16 muscles tested. Beef breeds were also over predicted in comparison with the cross and dairy breeds for six out of the 16 muscles tested. Therefore, even after accounting for differences in carcass traits, bulls still differ in eating quality when compared with females and steers. Breed also influenced eating quality beyond differences in carcass traits. However, in this case, it was only for certain muscles. This should be taken into account when estimating the eating quality of meat. In addition, the coefficients used by the Australian MSA model for some muscles, marbling score and ultimate pH do not exactly reflect the influence of these factors on eating quality in this data set, and if this system was to be applied to Europe then the coefficients for these muscles and covariates would need further investigation

    From Forbidden Coronal Lines to Meaningful Coronal Magnetic Fields

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    We review methods to measure magnetic fields within the corona using the polarized light in magnetic-dipole (M1) lines. We are particularly interested in both the global magnetic-field evolution over a solar cycle, and the local storage of magnetic free energy within coronal plasmas. We address commonly held skepticisms concerning angular ambiguities and line-of-sight confusion. We argue that ambiguities are in principle no worse than more familiar remotely sensed photospheric vector-fields, and that the diagnosis of M1 line data would benefit from simultaneous observations of EUV lines. Based on calculations and data from eclipses, we discuss the most promising lines and different approaches that might be used. We point to the S-like [Fe {\sc XI}] line (J=2 to J=1) at 789.2nm as a prime target line (for ATST for example) to augment the hotter 1074.7 and 1079.8 nm Si-like lines of [Fe {\sc XIII}] currently observed by the Coronal Multi-channel Polarimeter (CoMP). Significant breakthroughs will be made possible with the new generation of coronagraphs, in three distinct ways: (i) through single point inversions (which encompasses also the analysis of MHD wave modes), (ii) using direct comparisons of synthetic MHD or force-free models with polarization data, and (iii) using tomographic techniques.Comment: Accepted by Solar Physics, April 201

    ASCA and RXTE Observations of Non-Thermal X-ray Emission from Galactic Supernova Remnants: G156.2+5.7

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    (Abridged) We are conducting a survey of Galactic shell-type supernova remnants (SNRs) known or suspected to possess non-thermal components to their X-ray emission using new and archived observations made with such X-ray satellites as ROSAT, ASCA, RXTE, Chandra and XMM-Newton. This research is intended to probe the phenomenon of cosmic-ray acceleration by Galactic SNRs and estimate the maximum energy of cosmic-ray electrons accelerated by these sources. To illustrate this work, we examine the X-ray spectrum of the northwestern rim of an SNR suspected to have a non-thermal component to its X-ray emission, G156.2+5.7 (RX J04591+5147), over the energy range of approximately 0.7-12.0 keV using observations made by the ASCA GIS and the RXTE PCA. We compare fits made to the non-thermal component using two models, a simple power law and SRCUT. Both models give acceptable fits: the photon index derived from the fit made with the power law model, 2.0 (+0.2, -0.5), is comparable to values obtained for the bright rims of other SNRs with hard X-ray spectra. Using the SRCUT model, we derive a value of 2.42 (+0.24, -0.23) x 10^17 Hz for the cutoff frequency: based on this value and assuming a mean magnetic field strength of 14 microGauss, we estimate the cutoff energy of cosmic-ray electrons accelerated by G156.2+5.7 to be approximately 32 TeV. This energy value is well short of the "knee" feature of the cosmic-ray spectrum.Comment: 6 pages with 2 figures. This tex file uses the style file cospar.sty from Elvesier Science Publishers. To be published in Advances in Space Research, Proceedings of 34th COSPAR Assembly (October 2002), Symposium E1.4, "High Energy Studies of Supernova Remnants and Neutron Stars," eds. W. Hermsen and W. Becker (2003

    Untrained consumer assessment of the eating quality of European beef: 2. Demographic factors have only minor effects on consumer scores and willingness to pay

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    The beef industry must become more responsive to the changing market place and consumer demands. An essential part of this is quantifying a consumer’s perception of the eating quality of beef and their willingness to pay for that quality, across a broad range of demographics. Over 19 000 consumers from Northern Ireland, Poland, Ireland and France each tasted seven beef samples and scored them for tenderness, juiciness, flavour liking and overall liking. These scores were weighted and combined to create a fifth score, termed the Meat Quality 4 score (MQ4) (0.3×tenderness, 0.1×juiciness, 0.3×flavour liking and 0.3×overall liking). They also allocated the beef samples into one of four quality grades that best described the sample; unsatisfactory, good-every-day, better-than-every-day or premium. After the completion of the tasting panel, consumers were then asked to detail, in their own currency, their willingness to pay for these four categories which was subsequently converted to a proportion relative to the good-every-day category (P-WTP). Consumers also answered a short demographic questionnaire. The four sensory scores, the MQ4 score and the P-WTP were analysed separately, as dependant variables in linear mixed effects models. The answers from the demographic questionnaire were included in the model as fixed effects. Overall, there were only small differences in consumer scores and P-WTP between demographic groups. Consumers who preferred their beef cooked medium or well-done scored beef higher, except in Poland, where the opposite trend was found. This may be because Polish consumers were more likely to prefer their beef cooked well-done, but samples were cooked medium for this group. There was a small positive relationship with the importance of beef in the diet, increasing sensory scores by about 4% in Poland and Northern Ireland. Men also scored beef about 2% higher than women for most sensory scores in most countries. In most countries, consumers were willing to pay between 150 and 200% more for premium beef, and there was a 50% penalty in value for unsatisfactory beef. After quality grade, by far the greatest influence on P-WTP was country of origin. Consumer age also had a small negative relationship with P-WTP. The results indicate that a single quality score could reliably describe the eating quality experienced by all consumers. In addition, if reliable quality information is delivered to consumers they will pay more for better quality beef, which would add value to the beef industry and encourage improvements in quality

    A guanosine 5â€Č-triphosphate-dependent protein kinase is localized in the outer envelope membrane of pea chloroplasts

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    A guanosine 5-triphosphate (GTP)-dependent protein kinase was detected in preparations of outer chloroplast envelope membranes of pea (Pisum sativum L.) chloroplasts. The protein-kinase activity was capable of phosphorylating several envelope-membrane proteins. The major phosphorylated products were 23- and 32.5-kilo-dalton proteins of the outer envelope membrane. Several other envelope proteins were labeled to a lesser extent. Following acid hydrolysis of the labeled proteins, most of the label was detected as phosphoserine with only minor amounts detected as phosphothreonine. Several criteria were used to distinguish the GTP-dependent protein kinase from an ATP-dependent kinase also present in the outer envelope membrane. The ATP-dependent kinase phosphorylated a very different set of envelope-membrane proteins. Heparin inhibited the GTP-dependent kinase but had little effect upon the ATP-dependent enzyme. The GTP-dependent enzyme accepted phosvitin as an external protein substrate whereas the ATP-dependent enzyme did not. The outer membrane of the chloroplast envelope also contained a phosphotransferase capable of transferring labeled phosphate from [-32P]GTP to ADP to yield (-32P]ATP. Consequently, addition of ADP to a GTP-dependent protein-kinase assay resulted in a switch in the pattern of labeled products from that seen with GTP to that typically seen with ATP

    Review: The variability of the eating quality of beef can be reduced by predicting consumer satisfaction

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    Publication history: Accepted - 22 February 2018; Published online - 2 April 2018The Meat Standards Australia (MSA) grading scheme has the ability to predict beef eating quality for each ‘cut×cooking method combination’ from animal and carcass traits such as sex, age, breed, marbling, hot carcass weight and fatness, ageing time, etc. Following MSA testing protocols, a total of 22 different muscles, cooked by four different cooking methods and to three different degrees of doneness, were tasted by over 19 000 consumers from Northern Ireland, Poland, Ireland, France and Australia. Consumers scored the sensory characteristics (tenderness, flavor liking, juiciness and overall liking) and then allocated samples to one of four quality grades: unsatisfactory, good-every-day, better-than-every-day and premium. We observed that 26% of the beef was unsatisfactory. As previously reported, 68% of samples were allocated to the correct quality grades using the MSA grading scheme. Furthermore, only 7% of the beef unsatisfactory to consumers was misclassified as acceptable. Overall, we concluded that an MSA-like grading scheme could be used to predict beef eating quality and hence underpin commercial brands or labels in a number of European countries, and possibly the whole of Europe. In addition, such an eating quality guarantee system may allow the implementation of an MSA genetic index to improve eating quality through genetics as well as through management. Finally, such an eating quality guarantee system is likely to generate economic benefits to be shared along the beef supply chain from farmers to retailors, as consumers are willing to pay more for a better quality product.This research was supported by Meat and Livestock Australia and Murdoch University. Data were obtained through the financial contributions of the European research project ProSafeBeef (contract no. FOOD-CT-2006-36241), the Polish ProOptiBeef Farm to Fork project funded by the EU Innovative (POIG.01.03.01-00-204/09), the French ‘Direction GĂ©nĂ©rale de l’Alimentation’ and FranceAgriMer. For the Irish data, the authors acknowledge the financial support of the Department of Agriculture and the Marine (DAFM) under the Food Institutional Research Measure (FIRM). Furthermore, this project would not have been possible without the practical support of the Association Institut du Charolais, the Syndicat de DĂ©fense et du promotion de la Viande de Boeuf de Charolles and the gourmet restaurants ‘Jean Denaud’ and representatives of the beef industry across Europe. The international travel required for this project has been funded by ‘Egide/Fast’ funds from the French and Australian governments, respectively (project no. FR090054) and by ‘Egide/Polonium’ funds from the French and Polish governments, respectively. The assistance and participation of the Beef CRC and Janine Lau (MLA, Australia), Alan Gee (Cosign, Australia), Ray Watson (Melbourne University, Australia) and John Thompson (UNE) are also gratefully acknowledged
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