Avoidance of dental appointment due to cost and consequences for oral health-related quality of life: 25-yr follow-up of Swedish adults

We explored how socio-demographic and personal characteristics contribute to avoidance of dental appointment due to cost over time from age 55 (in 1997) to 75 (in 2017) and assessed the implications for oral health-related quality of life. In 1992, 6346 residents born in 1942 consented to participate in a prospective questionnaire survey, and 3060 (48.2%) of them completed postal follow-ups every fifth year until 2017. Oral health-related quality of life was assessed using the Oral Impact on Daily Performance inventory. The frequency of avoidance of dental appointment due to cost declined from 7.0% (in 1997) to 5.4% (in 2017), whereas the frequency of oral impacts declined from 26.0% in 2007 to 24.0% in 2017. Generalized Estimating Equation models revealed that avoidance of dental appointments due to cost was more likely reported in 1997 (OR: 1.5: 1.2–1.8) than in 2017, more likely in low educated people, and less likely in those using private dental care services. Avoidance of dental appointment due to cost was associated with impaired oral health-related quality of life. Social inequalities in avoidance of dental appointment due to cost and oral impacts did not vary across time but persisted into older ages despite the dental health care reforms that had been implemented.publishedVersio

RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia

Background While genome-wide association studies identified some promising candidates for schizophrenia, the majority of risk genes remained unknown. We were interested in testing whether integration gene expression and other functional information could facilitate the identification of susceptibility genes and related biological pathways. Results We conducted high throughput sequencing analyses to evaluate mRNA expression in blood samples isolated from 3 schizophrenia patients and 3 healthy controls. We also conducted pooled sequencing of 10 schizophrenic patients and matched controls. Differentially expressed genes were identified by t-test. In the individually sequenced dataset, we identified 198 genes differentially expressed between cases and controls, of them 19 had been verified by the pooled sequencing dataset and 21 reached nominal significance in gene-based association analyses of a genome wide association dataset. Pathway analysis of these differentially expressed genes revealed that they were highly enriched in the immune related pathways. Two genes, S100A8 and TYROBP, had consistent changes in expression in both individual and pooled sequencing datasets and were nominally significant in gene-based association analysis. Conclusions Integration of gene expression and pathway analyses with genome-wide association may be an efficient approach to identify risk genes for schizophrenia

A Cross-Disciplinary Outlook of Directions and Challenges in Industrial Electronics

[EN] How to build a sustainable society in view of industrial electronics has been discussed from energy, information and communication technologies, cyber-physical systems (CPSs), and other viewpoints. This paper presents a cross-disciplinary view that integrates the fields of human factors, professional education, electronic systems on chip, resilience and security for industrial applications, technology ethics and society, and standards. After explaining the efforts and challenges in these fields, this paper shows a methodology for cross-disciplinary technology that integrates the technical committees in Cluster 4, Industrial Electronics Society. A project, which was launched in March 2022, implements a 'Proof of Concept' trial of the methodology.The work of Jinhua Sh was supported by JSPS Grant-in-Aid for Scientific Research B under Grant 22H03998 (Japan).She, J.; Guzman-Miranda, H.; Huang, V.; Chen, AC.; Karnouskos, S.; Dunai, L.; Ma, C.... (2022). A Cross-Disciplinary Outlook of Directions and Challenges in Industrial Electronics. IEEE Journal of Emerging and Selected Topics in Industrial Electronics (Online). 3:375-391. https://doi.org/10.1109/OJIES.2022.3174218375391

Coexistence of Mobile Broadband IMT Systems and UWB Keyless Entry Systems above 6.5 GHz

The ever-increasing need for spectrum for mobile broadband systems has led to the recent allocation of spectral resources for International Mobile Telecommunication (IMT) services in the upper mid band (6.425 - 7.125 GHz) at the World Radio Conference (WRC-23) as well as to the creation of an agenda item on identifying future IMT bands in the frequency region 7.125 - 10.5 GHz at WRC-27. The severity of the impact of these frequency allocations on existing UWB systems, which have been using this part of the spectrum as a sub-secondary user for many years, is still subject to controversial discussions. This paper contributes a study on the impact of IMT on a real-world vehicular UWB keyless entry system to this discussion. It is shown that both the car's wireless on-board unit and a nearby basestation may drastically affect the system's performance

Infinite spin limit of semiclassical string states

Motivated by recent works of Hofman and Maldacena and Dorey we consider a special infinite spin limit of semiclassical spinning string states in AdS5 x S5. We discuss examples of known folded and circular 2-spin string solutions and demonstrate explicitly that the 1-loop superstring correction to the classical expression for the energy vanishes in the limit when one of the spins is much larger that the other. We also give a general discussion of this limit at the level of integral equations describing finite gap solutions of the string sigma model and argue that the corresponding asymptotic form of the string and gauge Bethe equations is the same.Comment: 38 pages, 3 figures; v2: comments on derivation of bound states of magnons from discrete Bethe equations added in section 4 and appendix C, references added, Imperial-TP-AT-6-4, HUTP-06/A002