Filamentation processes and dynamical excitation of light condensates in optical media with competing nonlinearities

We analyze both theoretically and by means of numerical simulations the phenomena of filamentation and dynamical formation of self-guided nonlinear waves in media featuring competing cubic and quintic nonlinearities. We provide a theoretical description of recent experiments in terms of a linear stability analysis supported with simulations, showing the possibility of experimental observation of the modulational instability suppression of intense light pulses travelling across such nonlinear media. We also show a novel mechanism of indirect excitation of {\em light condensates} by means of coalescence processes of nonlinear coherent structures produced by managed filamentation of high power laser beams.Comment: 6 pages, 4 figure

Analysis of an atom laser based on the spatial control of the scattering length

In this paper we analyze atom lasers based on the spatial modulation of the scattering length of a Bose-Einstein Condensate. We demonstrate, through numerical simulations and approximate analytical methods, the controllable emission of matter-wave bursts and study the dependence of the process on the spatial dependence of the scattering length along the axis of emission. We also study the role of an additional modulation of the scattering length in time.Comment: Submitted to Phys. Rev.

Determination of the species generated in atmospheric-pressure laser-induced plasmas by mass spectometry techniques

We present temporal information obtained by mass spectrometry techniques about the evolution of plasmas generated by laser filamentation in air. The experimental setup used in this work allowed us to study not only the dynamics of the filament core but also of the energy reservoir that surrounds it. Furthermore, valuable insights about the chemistry of such systems like the photofragmentation and/or formation of molecules were obtained. The interpretation of the experimental results are supported by PIC simulations

Plasma dynamics studies by mass spectrometry techniques

We present temporal information obtained by mass spectrometry techniques about the evolution of plasmas generated by laser filamentation in air. The experimental setup used in this work allowed us to study not only the dynamics of the filament core but also of the energy reservoir that surrounds it. Furthermore, valuable insights about the chemistry of such systems like the photofragmentation and/or formation of molecules were obtained. The interpretation of the experimental results are supported by PIC simulations

Two-Atom Collisions and the Loading of Atoms in Microtraps

We review light assisted collisions in a high-density far-off resonant optical trap (FORT). By tuning the parameters of the light that induces the collisions, the effects of the collisions can be controlled. Trap loss can be suppressed even at high atomic densities, allowing us to count the atoms using fluorescence detection. When only two atoms are trapped, individual loss events reveal new information about the process, and the simplicity of the system allows for a numerical simulation of the dynamics. By optimizing the experimental parameters, we implement an efficient method to prepare single atoms in the FORT. Our methods can be extended to load quantum registers for quantum information processing

Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data

Background: General anaesthesia (GA) during endovascular thrombectomy has been associated with worse patient outcomes in observational studies compared with patients treated without GA. We assessed functional outcome in ischaemic stroke patients with large vessel anterior circulation occlusion undergoing endovascular thrombectomy under GA, versus thrombectomy not under GA (with or without sedation) versus standard care (ie, no thrombectomy), stratified by the use of GA versus standard care. Methods: For this meta-analysis, patient-level data were pooled from all patients included in randomised trials in PuMed published between Jan 1, 2010, and May 31, 2017, that compared endovascular thrombectomy predominantly done with stent retrievers with standard care in anterior circulation ischaemic stroke patients (HERMES Collaboration). The primary outcome was functional outcome assessed by ordinal analysis of the modified Rankin scale (mRS) at 90 days in the GA and non-GA subgroups of patients treated with endovascular therapy versus those patients treated with standard care, adjusted for baseline prognostic variables. To account for between-trial variance we used mixed-effects modelling with a random effect for trials incorporated in all models. Bias was assessed using the Cochrane method. The meta-analysis was prospectively designed, but not registered. Findings: Seven trials were identified by our search; of 1764 patients included in these trials, 871 were allocated to endovascular thrombectomy and 893 were assigned standard care. After exclusion of 74 patients (72 did not undergo the procedure and two had missing data on anaesthetic strategy), 236 (30%) of 797 patients who had endovascular procedures were treated under GA. At baseline, patients receiving GA were younger and had a shorter delay between stroke onset and randomisation but they had similar pre-treatment clinical severity compared with patients who did not have GA. Endovascular thrombectomy improved functional outcome at 3 months both in patients who had GA (adjusted common odds ratio (cOR) 1·52, 95% CI 1·09–2·11, p=0·014) and in those who did not have GA (adjusted cOR 2·33, 95% CI 1·75–3·10, p<0·0001) versus standard care. However, outcomes were significantly better for patients who did not receive GA versus those who received GA (covariate-adjusted cOR 1·53, 95% CI 1·14–2·04, p=0·0044). The risk of bias and variability between studies was assessed to be low. Interpretation: Worse outcomes after endovascular thrombectomy were associated with GA, after adjustment for baseline prognostic variables. These data support avoidance of GA whenever possible. The procedure did, however, remain effective versus standard care in patients treated under GA, indicating that treatment should not be withheld in those who require anaesthesia for medical reasons