A investigação das atividades sociais e culturais dos intelectuais em redes sociais virtuais e seu impacto na cultura política estudantil

The present research is an applied one in terms of goals and in terms of the nature and type of study as a qualitative research and is an interpretative study that uses phenomenological research strategy to explain and interpret the essence of experience from the phenomenon of intellectuals’ social and cultural activities in virtual social networks and deep knowledge of this phenomenon on students' political culture. The results show that the role of intellectuals as conscious people and awakened conscience of society, whether in civil institutions and non-political social organizations, or in the state of belonging to political parties and political organizations, generally as individuals belonging to a social stratum, in some form it affects the political culture of the community, and contributes in the dynamics and awakening of the students' social and political consciousness, ultimately to the formation of national thought and feelings.La presente investigación es aplicada en términos de objetivos y en términos de la naturaleza y tipo de estudio como una investigación cualitativa y es un estudio interpretativo que utiliza una estrategia de investigación fenomenológica para explicar e interpretar la esencia de la experiencia del fenómeno de los intelectuales. y actividades culturales en redes sociales virtuales y conocimiento profundo de este fenómeno en la cultura política de los estudiantes. Los resultados muestran que el papel de los intelectuales como personas conscientes y conciencia despierta de la sociedad, ya sea en instituciones civiles y organizaciones sociales no políticas, o en el estado de pertenencia a partidos políticos y organizaciones políticas, generalmente como individuos pertenecientes a un estrato social, de alguna forma afecta la cultura política de la comunidad y contribuye en la dinámica y el despertar de la conciencia social y política de los estudiantes, en última instancia, a la formación del pensamiento y los sentimientos nacionales.Esta pesquisa é aplicada em termos de objetivos e em termos da natureza e tipo de estudo como uma pesquisa qualitativa e é um estudo interpretativo que utiliza uma estratégia de pesquisa fenomenológica para explicar e interpretar a essência da experiência do fenômeno de intelectuais e atividades culturais em redes sociais virtuais e profundo conhecimento desse fenômeno na cultura política dos alunos. Os resultados mostram que o papel dos intelectuais como pessoas conscientes e conscientes da sociedade, seja em instituições civis e organizações sociais não-políticas, seja no estado de pertencer a partidos políticos e organizações políticas, geralmente como indivíduos pertencentes a um estrato social, de alguma forma afeta a cultura política da comunidade e contribui para a dinâmica e o despertar da consciência social e política dos estudantes, em última instância, para a formação do pensamento e sentimentos nacionais

La investigación de las actividades sociales y culturales de intelectuales en las redes sociales virtuales y su impacto en la cultura política del estudiante

La presente investigación es aplicada en términos de objetivos y en términos de la naturaleza y tipo de estudio como una investigación cualitativa y es un estudio interpretativo que utiliza una estrategia de investigación fenomenológica para explicar e interpretar la esencia de la experiencia del fenómeno de los intelectuales. y actividades culturales en redes sociales virtuales y conocimiento profundo de este fenómeno en la cultura política de los estudiantes. Los resultados muestran que el papel de los intelectuales como personas conscientes y conciencia despierta de la sociedad, ya sea en instituciones civiles y organizaciones sociales no políticas, o en el estado de pertenencia a partidos políticos y organizaciones políticas, generalmente como individuos pertenecientes a un estrato social, de alguna forma afecta la cultura política de la comunidad y contribuye en la dinámica y el despertar de la conciencia social y política de los estudiantes, en última instancia, a la formación del pensamiento y los sentimientos nacionales

Effects of hyperbaric oxygen therapy on autistic behaviors and GRIN2B gene expression in valproic acid-exposed rats

IntroductionAutism is a complex neurodevelopmental condition characterized by deficits in social interaction, communication, and restricted repetitive behaviors. Hyperbaric oxygen therapy (HBOT) has emerged as a potential treatment for autism, although its effects on behavior and gene expression are not well understood. The GRIN2B gene, known for its involvement in encoding a glutamate receptor subunit crucial for neuron communication and associated with autism, was a focus of this study.MethodsUsing a rat model induced by prenatal exposure to valproic acid, we examined the impact of HBOT on autism-like behaviors and GRIN2B gene expression. Male Wistar rats were categorized into four groups: control, VPA (valproic acid-exposed), VPA+HBOT [2 atmosphere absolute (ATA)], and VPA+HBOT (2.5 ATA). The rats underwent several behavioral tests to assess social behavior, anxiety, stereotype and exploratory behaviors, and learning. Following the behavioral tests, the HBOT groups received 15 sessions of HBOT at pressures of 2 and 2.5 (ATA), and their behaviors were re-evaluated. Subsequently, real-time PCR was employed to measure GRIN2B gene expression in the frontal lobe.ResultsOur results indicated that HBOT significantly increased social interaction and exploratory behaviors in VPA-exposed rats, alongside elevated GRIN2B gene expression in their frontal lobe.DiscussionOur findings imply that HBOT might have a potential role in ameliorating autism-related behaviors in the VPA rat model of autism through potential modulation of GRIN2B gene expression. However, additional research is essential to fully comprehend the underlying mechanisms and refine the HBOT protocol for optimizing its effectiveness in improving autism-related symptoms

ERYTHROCYTE MEMBRANE FATTY ACIDS IN MULTIPLE SCLEROSIS PATIENTS AND HOT-NATURE DIETARY INTERVENTION WITH CO-SUPPLEMENTED HEMP-SEED AND EVENING-PRIMROSE OILS

The risk of developing multiple sclerosis (MS) is associated with increased dietary intake of saturated fatty acids. For many years it has been suspected that this disease might be associated with an imbalance between unsaturated and saturated fatty acids. We determined erythrocyte membrane fatty acids levels in Hot nature dietary intervention with co-supplemented hemp seed and evening primrose oils in multiple sclerosis patients. To determine the erythrocyte membrane fatty acids levels and correlate it with expanded disability status scale (EDSS) at baseline after 6 months intervention in MS patients by gas chromatography, in this double blind, randomized trial, 100 RRMS patients with EDS

Creating supply chain management strategy map with using causal loop diagram and balanced scorecard

Nowadays, organizations can use of main capabilities and competencies of other organizations to optimize abilities and increase the effectiveness of each other and elevate level of their customer satisfaction instead of having the best performance in all fields themselves. This participation requires an accurate and systematic management system and directing components’s goals of the chain in a common way as if it’s been neglected cause organization misses it’s competitive advantages and thus gives it’s competitive share to other competitors. Performance management system should facilitate balanced development in organization and play a key role in managing and mitigating conflicts within it. Moreover, it’s expected from Performance management system beside attention to financial measures, be able to reflect the characteristics that make advantages in modern business environment also beyond the financial standards, can consider other issues such human resources development, knowledge creation, innovation, processes development and promotion. More importantly, the performance management system should be linked with the vision and strategies. Balanced scorecard capabilities in covering the cases mentioned above cause it become a popular approach for performance management. This article points out some limitations of balanced scorecard approach and some potential and capacities of system dynamics as well, furthermore propose a new framework that is combining system dynamics causal loop diagram and balanced scorecard as a solution to improve the process of formulating a strategy map. Finally, after drawing the supply chain management causal loop diagram and creating balanced scorecard in related to it, supply chain management strategy map is achieved

Hepatoprotective effect of Crocus sativus (saffron) petals extract against acetaminophen toxicity in male Wistar rats

Objectives: Acetaminophen (APAP) toxicity is known to be common and potentially fatal. This study aims to investigate the protective effects of hydroalcoholic extract, remaining from Crocus sativus petals (CSP) against APAP-induced hepatotoxicity by measuring the blood parameters and studying the histopathology of liver in male rats. Materials and Methods: Wister rats (24) were randomly assigned into four groups including: I) healthy, receiving normal saline; II) Intoxicated, receiving only APAP (600 mg/kg); III) pre-treated with low dose of CSP (10 mg /kg) and receiving APAP (600 mg/kg); IV) pre-treated with high dose of CSP (20 mg/kg) and receiving APAP (600 mg/kg). Results: The APAP treatment resulted in higher levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and bilirubin, along with lower total protein and albumin concentration than the control group. The administration of CSP with a dose of 20 mg/kg was found to result in lower levels of AST, ALT and bilirubin, with a significant higher concentration of total protein and albumin. The histopathological results regarding liver pathology, revealed sever conditions including cell swelling, severe inflammation and necrosis in APAP-exposed rats, which was quiet contrasting compared to the control group. The pre-treated rats with low doses of ‍CSP showed hydropic degeneration with mild necrosis in centrilobular areas of the liver, while the same subjects with high doses of ‍CSP appeared to have only mild hepatocyte degeneration. Conclusions: Doses of 20 mg/kg of CSP ameliorates APAP–induced acute liver injury in rats. It was concluded that the antioxidant property of CSP resulted in reducing the oxidative stress complications of toxic levels of APAP in intoxicated rats

Anterior Chamber Contamination at the Conclusion of Phacoemulsification

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 </style> <![endif]--> <p>PURPOSE: To evaluate anterior chamber aspirates at the conclusion of phacoemulsification and intraocular lens implantation (PE+IOL) for bacterial and fungal contamination. METHODS: We prospectively evaluated 80 eyes of 80 patients undergoing routine PE+IOL by performing bacterial and fungal culture on aspirates obtained from the anterior chamber at the end of the surgery. RESULTS: Anterior chamber fluid aspirates were positive for bacteria in 5 eyes (6.33%) with coagulase-negative staphylococcus being the most common organism (three eyes). No instance of positive fungus culture was observed. One of the culture-positive eyes developed postoperative uveitis which resolved during a week of treatment with topical corticosteroids and antibiotics.  None of the eyes developed endophthalmitis. CONCLUSION: In the current series, the rate of anterior chamber contamination by bacteria at the end of phacoemulsification was in the lower range reported by previous studies.  </p> <!--[if gte mso 9]><xml> Normal 0 false false false MicrosoftInternetExplorer4 </xml><![endif]--><!--[if gte mso 9]><xml> </xml><![endif]--> <!--[if gte mso 10]> <style>
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Association of Expanded Disability Status Scale and Cytokines after Intervention with Co-supplemented Hemp Seed, Evening Primrose Oils and Hot-natured Diet in Multiple Sclerosis Patients

Introduction: Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Because of limited efficacy and adverse side effects, identifying novel therapeutic and protective agents is important. The aim of this study is to examine the correlations between expanded disability status scale (EDSS) and cytokines after intervention with co-supplemented hemp seed and evening primrose oils and hot-natured diet in patients with relapsing-remitting multiple sclerosis (RRMS). Methods: We studied a group of 23 patients with clinically definite RRMS, with EDSS<6 who received co-supplemented hemp seed and evening primrose oils with advising hot-natured diet. Clinically EDSS and immunological factors (plasma cytokines of IL-4, IFN-γ and IL-17) were assessed at baseline and after 6 months. Results: Mean follow-up was 180±2.9 days (N=23, 7 Male and 16 Females aged 25.0±7.5 years with disease duration 6.26±3.9 years). After 6 months, significant improvements in extended disability status score were found in the patients in agreement with decrease cytokines of IFN-γ and IL-17 and increase cytokines of IL-4. Clinical and immunological parameters showed improvement in the patients after the intervention. Conclusion: Our study shows that co-supplemented hemp seed and evening primrose oils with hot-natured diet can have beneficial effects in improving clinical symptoms in relapsing remitting MS patients and significant correlation was found between EDSS and immunological findings