Religious affiliation and extramarital sex among men in Brazil.

CONTEXT: Since 1990, HIV infection in Brazil has spread among the heterosexual population, particularly in the north. Containment of the epidemic can be informed by a better understanding of men's sexual risk behavior. METHODS: Logistic, Poisson and multilevel logit models were applied to data on married and cohabiting men who had participated in the 1996 Brazilian Demographic and Health Survey. RESULTS: Twelve percent of married or cohabiting men reported having had at least one extramarital partner in the previous 12 months; half of these had had two or more. The majority (77%) of partners were described as friends or lovers; 4% had been prostitutes and 15% strangers. Among men who had had sex with an extramarital partner in the last year, 40% reported having used condoms during last extramarital sex. Compared with members of evangelical religions, other men were significantly more likely to report having had an extramarital partner (odds ratios, 3.0-4.7) and unprotected extramarital sex in the last 12 months (3.4-7.9). Region of residence was also strongly correlated with extramarital sex: Compared with men in southern or central Brazil, those in the north had more than three times the odds of having had extramarital sex and unprotected extramarital sex in the last year (3.1-3.8). CONCLUSION: In Brazil, religious affiliation and region of residence exert a major influence on risk behavior

MAT-717: MECHANICAL PERFORMANCE OF HYBRID FIBRE-REINFORCED ENGINEERED CEMENTITIOUS COMPOSITE INCORPORATING NITISMA SHORT FIBRES

A new high-strength, high-tensile ductility hybrid fibre-reinforced engineered cementitious composite (HECCSMAF) incorporating randomly dispersed nickel-titanium shape memory alloy short fibres (NiTi-SMA) has been pioneered in this study. The mechanical properties of the HECC-SMAF produced with a combination of 2% polyvinyl-alcohol (PVA) and 0.5%, 1%, and 1.5% NiTi-SMA fibres by volume fraction have been explored. The experimental results indicate that utilizing a combination of those fibres can enhance the tensile capacity of ECC by up to 39% with a slight to no increase in compressive strength. An overall reduction in workability was observed compared to that of ECC made with only 2% PVA by volume fraction, which is typical of metallic fibre-reinforced cementitious systems. Among the tested ECC mixtures, HECC-SMAF made with 2% PVA and 1% NiTi-SMA presents the best mechanical performance

Optimization of growth and extracellular glucoamylase production by Candida famata isolate

Candida famata was isolated from traditional Moroccan sourdough. It exhibited high glucoamylase and biomass production. Starch induces high glucoamylase production C. famata with maximum glucoamylase activity at 5 g/L. Glucose stimulates good production in biomass but strongly inhibitsglucoamylase production. Among the sources of nitrogen tested, yeast extract and the (NH4)2HPO4 gave maximum glucoamylase and biomass after 72 h of incubation in liquid medium at 30°C, pH 5 and 105 rpm

Tioconazole and Chloroquine Act Synergistically to Combat Doxorubicin-Induced Toxicity via Inactivation of PI3K/AKT/mTOR Signaling Mediated ROS-Dependent Apoptosis and Autophagic Flux Inhibition in MCF-7 Breast Cancer Cells.

Cancer is a complex devastating disease with enormous treatment challenges, including chemo- and radiotherapeutic resistance. Combination therapy demonstrated a promising strategy to target hard-to-treat cancers and sensitize cancer cells to conventional anti-cancer drugs such as doxorubicin. This study aimed to establish molecular profiling and therapeutic efficacy assessment of chloroquine and/or tioconazole (TIC) combination with doxorubicin (DOX) as anew combination model in MCF-7 breast cancer. The drugs are tested against apoptotic/autophagic pathways and related redox status. Molecular docking revealed that chloroquine (CQ) and TIC could be potential PI3K and ATG4B pathway inhibitors. Combination therapy significantly inhibited cancer cell viability, PI3K/AkT/mTOR pathway, and tumor-supporting autophagic flux, however, induced apoptotic pathways and altered nuclear genotoxic feature. Our data revealed that the combination cocktail therapy markedly inhibited tumor proliferation marker (KI-67) and cell growth, along with the accumulation of autophagosomes and elevation of LC3-II and p62 levels indicated autophagic flux blockage and increased apoptosis. Additionally, CQ and/or TIC combination therapy with DOX exerts its activity on the redox balance of cancer cells mediated ROS-dependent apoptosis induction achieved by GPX3 suppression. Besides, Autophagy inhibition causes moderately upregulation in ATGs 5,7 redundant proteins strengthened combinations induced apoptosis, whereas inhibition of PI3K/AKT/mTOR pathway with Beclin-1 upregulation leading to cytodestructive autophagy with overcome drug resistance effectively in curing cancer. Notably, the tumor growth inhibition and various antioxidant effects were observed in vivo. These results suggest CQ and/or TIC combination with DOX could act as effective cocktail therapy targeting autophagy and PI3K/AKT/mTOR pathways in MCF-7 breast cancer cells and hence, sensitizes cancer cells to doxorubicin treatment and combat its toxicity

Morphological Variation between Life and Death Gastropod Populations in the Nile Delta: A Pollution-Induced Evolution

Wetland ecosystems of the Nile Delta face severe threats due to natural climatic changes and anthropogenic activities. Life and death assemblage comparisons can be implemented as a historical record to detect anthropogenic-induced environmental changes in the past few decades. A geometric morphometric approach was applied to quantify the pollution-induced morphological variation between life and death populations of the gastropod Melanoides tuberculata. The results indicated that life populations differ significantly from the death ones, where the first tend to be much smaller, more globular, and with a depressed aperture and whorl section. In addition, the phenetic diversity of the life populations was also decreased, and the allometric growth was shifted. These morphological changes in the life populations are well-known adaptations for reducing the cost of shell maintenance in polluted water. No distinct morphospace was found between life populations from different habitats, suggesting that habitats have no significant role in the current pollution-induced evolution.This work is funded by the Researchers Supporting Project number (RSP2023R455), King Saud University, Riyadh, Saudi Arabia

MAT-741: IMPACT BEHAVIOUR OF SHAPE MEMORY ALLOY HYBRID FIBRE-REINFORCED ENGINEERED CEMENTITIOUS COMPOSITE

An experimental study was conducted to evaluate the impact behaviour of an innovative hybrid-fibre engineered cementitious composite (ECC) incorporating randomly dispersed short shape memory alloy fibres (SMA). A modified drop weight test was conducted on specimens from various ECC mixtures with and without SMA fibres. The impact behaviour was evaluated and compared based on the ability to dissipate energy and sustain impact load without damage. Results show that the addition of SMA to ECC mixtures significantly enhanced their performance under impact loading. The amount of dissipated energy by ECC increased by about 51% as a result of SMA fibre addition. This highlights the potential benefits of incorporating SMA in composite materials exposed to impact loads, paving the way for a wider implementation in the field of fortified structures

Influence of Some Innovation Attributes on the Adoption of Growing Sunflower in Rahad Scheme

The vital economic importance of sunflower as one of the oil crops encouraged its introduction to the Sudan in the last twenty years. The production of sunflower crop began in Rahad scheme, as in other irrigated areas in the country, in 1992/93 growing season. Field survey was used to collect data from 100 sunflower growers (adopters) in Rahad Scheme (block 10) in 2002/2003 growing season selected from a total population of 1000-1100 farmers by using the simple random sample technique. An equal number of non-adopters was selected for comparison. The total number of interviewed farmers was 200. The collected data was statistically analyzed using the chi-square test. The results showed significant association (dependency) between adoption of growing sunflower (the innovation) and some of its attributes: Relative advantage on perceived production cost and income, compatibility with farmers need as cash crop and animal feed, complexity associated with use of technical package for sunflower. From the findings of this study, we can conclude that the adoption of this crop was dependent on some innovation attributes and the results were expected to reveal factors influencing adoption of the crop. The authors recommend that more attention should be given by agronomists to this crop in order to improve the yield of the crop and extension services should design special programs for the crop to promote its rate of adoption

The Conditions of Amplification for Nano Quantum Diodes

It is well known that nanomaterials are described by quantum laws. In this work quantum treatment for two metal contacts or diodes on a nanoscale was done. A useful expression for the input and output current is found by using the notion of the current density in quantum mechanics. The conditions required by this contact to act as a rectifier and amplifier are discussed. It found that certain restrictions should be imposed on the potential and the wave number for the metal contact to act as an amplifier. This requires the potential barrier to be positive this requires the region of incident current to have work function less than the transmuted one