Representação computacional das construções de sujeito-predicado do português do Brasil

Este trabalho apresenta uma proposta para representar computacionalmente construções do Português Brasileiro, no âmbito do Constructicon da FrameNet Brasil. Dessa forma, demonstra de que maneira as teorias irmãs da Semântica de Frames e da Gramática das Construções podem ser implementadas computacionalmente com vias a sustentar aplicações em Compreensão de Língua Natural. </p

Surgical aortic valve replacement and patient-prosthesis mismatch a meta-analysis of 108 182 patients

OBJECTIVES: This study sought to evaluate the impact of patient–prosthesis mismatch (PPM) on the risk of perioperative, early-, mid- and long-term mortality rates after surgical aortic valve replacement. METHODS: Databases were searched for studies published until March 2018. The main outcomes of interest were perioperative mortality, 1-year mortality, 5-year mortality and 10-year mortality. RESULTS: The search yielded 3761 studies for inclusion. Of these, 70 articles were analysed, and their data were extracted. The total num- ber of patients included was 108 182 who underwent surgical aortic valve replacement. The incidence of PPM after surgical aortic valve re- placement was 53.7% (58 116 with PPM and 50 066 without PPM). Perioperative mortality [odds ratio (OR) 1.491, 95% confidence interval (CI) 1.302–1.707; P < 0.001], 1-year mortality (OR 1.465, 95% CI 1.277–1.681; P < 0.001), 5-year mortality (OR 1.358, 95% CI 1.218–1.515; P < 0.001) and 10-year mortality (OR 1.534, 95% CI 1.290–1.825; P < 0.001) were increased in patients with PPM. Both severe PPM and moderate PPM were associated with increased risk of perioperative mortality, 1-year mortality, 5-year mortality and 10-year mortality when analysed together and separately, although we observed a higher risk in the group with severe PPM. CONCLUSIONS: Moderate/severe PPM increases perioperative, early-, mid- and long-term mortality rates proportionally to its severity. The findings of this study support the implementation of surgical strategies to prevent PPM in order to decrease mortality rates

AVALIAÇÃO DO RISCO DE QUEDAS E QUALIDADE DE VIDA DOS IDOSOS COM ACIDENTE VASCULAR ENCEFÁLICO

http://dx.doi.org/10.5902/2236583411720O presente estudo caracteriza-se por ser randomizado, sendo avaliados, risco de quedas, capacidade funcional, equilíbrio corporal e qualidade de vida, através da escala de Dawton, escala de Medida de Independência Funcional, escala de Berg, The Medical Outcomes Study 36-item Short-Form Health Survey (SF-36), respectivamente. Foram avaliados os idosos com Acidente Vascular Encefálico, sendo 10 idosos institucionalizados (grupo I) e 10 idosos não institucionalizados (grupo II). Ao avaliar o equilíbrio e risco de quedas em ambos os grupos obteve-se diferença estatisticamente significativa, sendo que as médias para ambos foram favoráveis para os idosos do grupo II demonstrando que os idosos do grupo I estão mais propensos a quedas. Os resultados para análise da capacidade funcional também apresentaram diferença estatisticamente significativa, sendo que os idosos do grupo I obtiveram menor capacidade funcional. Conclui-se que idosos com sequela de Acidente Vascular Encefálico do grupo I apresentaram alto índice de quedas, além de menor capacidade funcional

Brazilian recommendations on the safety and effectiveness of the yellow fever vaccination in patients with chronic immune-mediated inflammatory diseases

Background: In Brazil, we are facing an alarming epidemic scenario of Yellow fever (YF), which is reaching the most populous areas of the country in unvaccinated people. Vaccination is the only effective tool to prevent YF. In special situations, such as patients with chronic immune-mediated inflammatory diseases (CIMID), undergoing immunosuppressive therapy, as a higher risk of severe adverse events may occur, assessment of the risk-benefit ratio of the yellow fever vaccine (YFV) should be performed on an individual level. Main body of the abstract: Faced with the scarcity of specific orientation on YFV for this special group of patients, the Brazilian Rheumatology Society (BRS) endorsed a project aiming the development of individualized YFV recommendations for patients with CIMID, guided by questions addressed by both medical professionals and patients, followed an internationally validated methodology (GIN-McMaster Guideline Development). Firstly, a systematic review was carried out and an expert panel formed to take part of the decision process, comprising BRS clinical practitioners, as well as individuals from the Brazilian Dermatology Society (BDS), Brazilian Inflammatory Bowel Diseases Study Group (GEDIIB), and specialists on infectious diseases and vaccination (from Tropical Medicine, Infectious Diseases and Immunizations National Societies); in addition, two representatives of patient groups were included as members of the panel. When the quality of the evidence was low or there was a lack of evidence to determine the recommendations, the decisions were based on the expert opinion panel and a Delphi approach was performed. A recommendation was accepted upon achieving ≥80% agreement among the panel, including the patient representatives. As a result, eight recommendations were developed regarding the safety of YFV in patients with CIMID, considering the immunosuppression degree conferred by the treatment used. It was not possible to establish recommendations on the effectiveness of YFV in these patients as there is no consistent evidence to support these recommendations. Conclusion: This paper approaches a real need, assessed by clinicians and patient care groups, to address specific questions on the management of YFV in patients with CIMID living or traveling to YF endemic areas, involving specialists from many areas together with patients, and might have global applicability, contributing to and supporting vaccination practices. We recommended a shared decision-making approach on taking or not the YFV

AUTISMO E COMORBIDADES PSIQUIÁTRICAS: UMA ANÁLISE CRÍTICA NA LITERATURA - UMA REVISÃO SISTEMÁTICA COM ENFOQUE NA REVISÃO DE LITERATURA

The present study carries out a critical analysis of the literature on autism and its psychiatric comorbidities, focusing on a systematic review of existing research. Based on an extensive review of scientific articles, theses and relevant studies, this literature review aims to deepen the understanding of the complex interactions between autism and associated psychiatric disorders. By exploring the available evidence, we highlight the need for a critical approach to understanding the coexistence of autism with psychiatric conditions such as anxiety, depression and obsessive-compulsive disorder. The systematic review offers a synthesis of the most recent findings, addressing not only the diagnostic challenges, but also the clinical and therapeutic impacts of these comorbidities. Furthermore, this review emphasizes the importance of holistic intervention strategies, considering both the specific aspects of autism and the needs associated with psychiatric disorders. The study highlights gaps in the existing literature, pointing to areas in need of future research to improve understanding and clinical management of these complex conditions. In summary, the systematic review offers a significant contribution to the field, providing a critical and comprehensive overview of the relationships between autism and psychiatric comorbidities, shedding light on clinical challenges, recent advances, and promising directions for future research. critical to understanding not only the diagnostic aspects, but also the clinical and therapeutic impacts of psychiatric comorbidities in the context of autism. The study addresses the nuances in clinical manifestations, recognizing that the presence of disorders such as anxiety, depression and obsessive-compulsive disorder can significantly influence the trajectory and quality of life of individuals on the autism spectrum.O presente estudo realiza uma análise crítica da literatura sobre o autismo e suas comorbidades psiquiátricas, enfocando uma revisão sistemática da pesquisa existente. Com base em uma extensa revisão de artigos científicos, teses e estudos relevantes, esta revisão de literatura visa aprofundar a compreensão das complexas interações entre o autismo e distúrbios psiquiátricos associados. Ao explorar as evidências disponíveis, destacamos a necessidade de uma abordagem crítica para entender a coexistência do autismo com condições psiquiátricas, como ansiedade, depressão e transtorno obsessiva-compulsivos. A revisão sistemática oferece uma síntese das descobertas mais recentes, abordando não apenas os desafios diagnósticos, mas também os impactos clínicos e terapêuticos dessas comorbidades. Ademais, esta revisão enfatiza a importância de estratégias de intervenção holísticas, considerando tanto os aspectos específicos do autismo quanto as necessidades associadas aos transtornos psiquiátricos. O estudo destaca lacunas na literatura existente, apontando para áreas que necessitam de pesquisas futuras para aprimorar a compreensão e o manejo clínico dessas condições complexas. Em síntese, a revisão sistemática oferece uma contribuição significativa ao campo, proporcionando uma visão crítica e abrangente das relações entre o autismo e comorbidades psiquiátricas, lançando luz sobre desafios clínicos, avanços recentes e direções promissoras para pesquisas futuras A revisão destaca a importância de uma abordagem crítica para compreender não apenas os aspectos diagnósticos, mas também os impactos clínicos e terapêuticos das comorbidades psiquiátricas no contexto do autismo. O estudo aborda as nuances nas manifestações clínicas, reconhecendo que a presença de transtornos como ansiedade, depressão e transtorno obsessiva-compulsivos pode influenciar significativamente a trajetória e qualidade de vida de indivíduos no espectro do autismo